詹姆斯·布莱克（Black James，1924年6月14日～2010年3月22日），苏格兰药理学家，诺贝尔生理学或医学奖获得者，曾任英国邓迪大学校长。

詹姆斯·布莱克（Black James，1924-2010），苏格兰药理学家，因为在β-受体阻滞剂方面的工作，布莱克于1988年获得了诺贝尔生理学或医学奖。美国心脏病协会主席克莱德·杨西说：“数百万的病人轻松地就得到了β-受体阻滞疗法的帮助。”

詹姆斯·布莱克（James Black）1924年6月14日出生于英国苏格兰拉纳克郡，2010年3月22日逝世，享年85岁。因为在β-受体阻滞剂方面的工作，布莱克于1988年获得了诺贝尔生理学或医学奖。他发明了广泛使用的药物——心得安（propranolol），迄今还在被许多患有心脏病的病人所服用。2006年之前，他一直担任英国邓迪大学校长。

https://baike.baidu.com/item/%E8%A9%B9%E5%A7%86%E6%96%AF%C2%B7%E5%B8%83%E8%8E%B1%E5%85%8B/4446425?fromModule=lemma_inlink&fromtitle=%E8%A9%B9%E5%A7%86%E5%A3%AB%C2%B7W%C2%B7%E5%B8%83%E6%8B%89%E5%85%8B&fromid=8016380

https://pubmed.ncbi.nlm.nih.gov/18309531/

https://pubmed.ncbi.nlm.nih.gov/16134017/

summary-BlackJ-set.txt

Abstract

This lecture outlines the early stages in the discovery of adrenaline beta-receptor antagonists and of the histamine H2-receptor antagonists. It ends with a brief personal view about future research.

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Publication types

• Lecture

MeSH terms

• Adrenergic beta-Antagonists / pharmacology*

• Animals

• Biochemistry / methods*

• Biology / methods

• Chemistry, Pharmaceutical / methods

• Histamine / chemistry

• Histamine H2 Antagonists / chemistry

• Histamine H2 Antagonists / pharmacology*

• Hormones / chemistry

• Humans

• Kinetics

• Models, Chemical

• Nobel Prize

• Oxygen Consumption

• Receptors, Adrenergic, beta / chemistry*

• Receptors, Histamine H2 / drug effects

• Structure-Activity Relationship

Substances

• Adrenergic beta-Antagonists

• Histamine H2 Antagonists

• Hormones

• Receptors, Adrenergic, beta

• Receptors, Histamine H2

• Histamine

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