许培扬博客分享 http://blog.sciencenet.cn/u/xupeiyang 跟踪国际前沿 服务国内科研

博文

诺奖发现 神经退行性疾病

已有 1327 次阅读 2022-9-25 14:40 |个人分类:诺贝尔奖|系统分类:论文交流



长谷川成人,日本东京都医学科学研究所脑神经科学部主任

Virginia Man-Yee Lee,美国宾夕法尼亚大学病理学和实验医学系阿尔茨海默病研究John H. Ware 3rd 讲席教授、神经退行性疾病研究中心主任

获奖原因:发现TDP-43以及对神经退行性疾病研究的其他贡献。TDP-43是肌萎缩性脊髓侧索硬化症(ALS)和额颞叶变性(FTLD)的病理特征。

https://news.sciencenet.cn/htmlnews/2022/9/486641.shtm

https://pubmed.ncbi.nlm.nih.gov/17095949/



Review

 

Ann Pharm Fr

2006 Sep;64(5):291-307.

 doi: 10.1016/s0003-4509(06)75322-6.

[A Nematode Nobel Prize: Caenorhabditis elegans]

[Article in French]

J Savel 1F Clostre

Affiliations expand

Abstract

The Nematode Caenorhabditis elegans (C. elegans) is an established model increasingly used for studying human disease pathogenesis. C. elegans models are based on the mutagenesis of human disease genes conserved in this Nematode or on the transgenesis with disease genes not conserved in C. elegans. Genetic examinations will give new insights on the cellular and molecular mechanisms that are altered in some neurodegenerative diseases like Duchenne's muscular dystrophy, Huntington's disease and Alzheimer's disease. C. elegans may be used for primary screening of new compounds that may be used as drugs in these diseases.

Similar articles

See all similar articles

Publication types

  • English Abstract

  • Review

MeSH terms

  • Alzheimer Disease / genetics

  • Alzheimer Disease / physiopathology

  • Animals

  • Bacterial Infections / physiopathology

  • Caenorhabditis elegans / genetics

  • Caenorhabditis elegans / microbiology

  • Caenorhabditis elegans / physiology*

  • Disease Models, Animal

  • Gametogenesis

  • Humans

  • Huntington Disease / genetics

  • Huntington Disease / physiopathology

  • Muscular Dystrophy, Duchenne / genetics

  • Muscular Dystrophy, Duchenne / physiopathology

  • Neurobiology

  • Nobel Prize

  • Reproduction

Related information

LinkOut - more resources

http://www.pubmedplus.cn/P/SearchQuickResult?wd=89310736-f09f-4055-9212-0df3cd0b9bbb

01.20201 篇1.887%
02.20192 篇3.774%
03.20181 篇1.887%
04.20172 篇3.774%
05.20162 篇3.774%
06.20151 篇1.887%
07.20144 篇7.547%
08.20131 篇1.887%
09.20112 篇3.774%
10.20101 篇1.887%
11.20092 篇3.774%
12.20071 篇1.887%
13.20062 篇3.774%
14.20041 篇1.887%
15.20023 篇5.660%
16.20015 篇9.434%
17.20003 篇5.660%
18.19981 篇1.887%
19.199712 篇22.642%
20.19773 篇5.660%
21.19763 篇5.660%
01.nature5 篇9.434%
02.science4 篇7.547%
03.jama3 篇5.660%
04.lakartidningen3 篇5.660%
05.duodecim2 篇3.774%
06.lancet2 篇3.774%
07.ned tijdschr geneeskd2 篇3.774%
08.tidsskr nor laegeforen2 篇3.774%
09.acta paediatr1 篇1.887%
10.adv exp med biol1 篇1.887%
01.英国4 篇7.547%
02.美国3 篇5.660%
03.中国2 篇3.774%
04.荷兰2 篇3.774%
05.法国1 篇1.887%
06.芬兰1 篇1.887%
07.日本1 篇1.887%
08.瑞典1 篇1.887%
09.沙特阿拉伯1 篇1.887%
10.以色列1 篇1.887%
01.中国苏州1 篇1.887%
01.Nobel Prize53 篇100.000%
02.Humans46 篇86.792%
03.History, 20th Century36 篇67.925%
04.Animals23 篇43.396%
05.Prion Diseases18 篇33.962%
06.United States17 篇32.075%
07.Prions14 篇26.415%
08.History, 21st Century12 篇22.642%
09.Parkinson Disease11 篇20.755%
10.Kuru9 篇16.981%

常用聚类 分析报告导出

年份期刊国家中国城市境外城市主题词

www.newpubmed.com

关注微博公众号

地址:北京市海淀区远大路20号宝蓝世纪大厦F座5E




https://m.sciencenet.cn/blog-280034-1356768.html

上一篇:诗书画唱 70期 楷草二体书法作品 千字文
下一篇:诺奖发现 镰状细胞贫血

1 杨学祥

该博文允许注册用户评论 请点击登录 评论 (0 个评论)

数据加载中...

Archiver|手机版|科学网 ( 京ICP备07017567号-12 )

GMT+8, 2024-3-29 07:04

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社

返回顶部