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诺奖发现 论文代表作 发现RNA干扰——双链RNA引发的沉默现象

已有 609 次阅读 2022-10-6 08:02 |个人分类:诺贝尔奖|系统分类:论文交流



2006年

安德鲁·法厄

美国

斯坦福大学(美国)

发现RNA干扰——双链RNA引发的沉默现象

克雷格·梅洛

美国

马萨诸塞大学(美国)



https://baike.baidu.com/item/%E8%AF%BA%E8%B4%9D%E5%B0%94%E7%94%9F%E7%90%86%E5%AD%A6%E6%88%96%E5%8C%BB%E5%AD%A6%E5%A5%96/1310224


论文代表作

http://www.pubmedplus.cn/P/SearchQuickResult?wd=b7acd9d4-ff8e-419f-8501-e1c684adf6d8




https://pubmed.ncbi.nlm.nih.gov/18007671/

summary-18007671.txt

Cell Death Differ

2007 Dec;14(12):1998-2012.

 doi: 10.1038/sj.cdd.4402253.

Gene silencing by double-stranded RNA

Andrew Z Fire

Abstract

Thanks to the Nobel Foundation for permission to publish this Lecture. We report here the Nobel Lecture delivered by Professor Andrew Z Fire. Together with the accompanying lecture by Professor Mello this lecture describes the exciting years leading to the discovery of RNA interference (RNAi) and some of the underlying molecular mechanisms. Professor Fire nicely points out his own contribution and the contribution of other research groups to the development of this field. He also presents an interesting discussion on the role of RNAi in immunity and challenges us with a number of open questions. The lecture ends presenting the great potential of exploiting RNAi for therapeutical purposes.

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Publication types

  • Lecture

MeSH terms

  • Animals

  • Caenorhabditis elegans / genetics

  • Gene Silencing*

  • Immunity

  • Models, Biological

  • RNA Interference

  • RNA, Double-Stranded / metabolism*

Substances

  • RNA, Double-Stranded

Related information

LinkOut - more resources


相关文献检索分析结果如下

http://www.pubmedplus.cn/P/SearchQuickResult?wd=406c610a-1654-4f87-94b9-624a14fd85f4


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