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20130601 paper

已有 3021 次阅读 2013-6-1 23:07 |个人分类:paper reading|系统分类:科研笔记|关键词:学者

An Inherently Bifunctional Subset of Foxp3+ T Helper Cells Is Controlled by the Transcription Factor Eos

 

  • Highlights

  • A subset of Treg cells shows labile expression of the corepressor Eos

  • These Treg cells can reprogram into helper cells without losing Foxp3

  • Eos-labile Treg cells are constitutively present in thymus, lymph nodes, and spleen

  • Reprogrammed Treg cells can help support priming of effector T cells to new antigen



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