Cell—科学家使用TALENs编辑技术建立Rett综合征猴模型

Abstract

Summary

1.Generation of MECP2 Mutant Cynomolgus Monkeys via TALENs

2.Dynamic Changes of Cortical and Sub-cortical Volume Monitored by MRI Scanning

3.The EKG of MECP2 Mutant and WT Monkeys

4.Behavioral Phenotypes of MECP2 Mutant Monkeys

5.Eye-Tracking Patterns in MECP2 Mutants and WT Monkeys