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科学家 Patrick O Brown（基因组学）
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Patrick O Brown |
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| Head of Section: Genomics & Genetics > Genomics [ since 18 July 2001 ] |
部分论著与科研绩效：
http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0
pnas.org [HTML]MB Eisen, PT Spellman, PO Brown, … - Proceedings of the …, 1998 - National Acad Sciences
A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
is described that uses standard statistical algorithms to arrange genes according to similarity
in pattern of gene expression. The output is displayed graphically, conveying the ...
Cited by 9913 - Related articles - BL Direct - All 187 versions
A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
is described that uses standard statistical algorithms to arrange genes according to similarity
in pattern of gene expression. The output is displayed graphically, conveying the ...
Cited by 9913 - Related articles - BL Direct - All 187 versions
[CITATION] Quantitative monitoring of gene expression patterns with a complementary DNA microarray
Cited by 6923 - Related articles - BL Direct - All 22 versions
cmu.edu [PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, PO Brown, … - Nature, 2000 - nature.com
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have
prolonged survival, whereas the remainder succumb to the disease. We proposed that ...
Cited by 5096 - Related articles - BL Direct - All 82 versions
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have
prolonged survival, whereas the remainder succumb to the disease. We proposed that ...
Cited by 5096 - Related articles - BL Direct - All 82 versions
… , SX Zhu, PE Lønning, AL Børresen-Dale, PO Brown, D … - Nature, 2000 - nature.com
Human breast tumours are diverse in their natural history and in their responsiveness to treatments
1 . Variation in transcriptional programs accounts for much of the biological diversity of human
cells and tumours. In each cell, signal transduction and regulatory systems transduce ...
Cited by 3713 - Related articles - BL Direct - All 12 versions
Human breast tumours are diverse in their natural history and in their responsiveness to treatments
1 . Variation in transcriptional programs accounts for much of the biological diversity of human
cells and tumours. In each cell, signal transduction and regulatory systems transduce ...
Cited by 3713 - Related articles - BL Direct - All 12 versions
ramapo.edu [PDF]JL DeRisi, VR Iyer, PO Brown - Science, 1997 - sciencemag.org
DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
carry out a comprehensive investigation of the temporal program of gene expression accompanying
the metabolic shift from fermentation to respiration. The expression profiles observed for ...
Cited by 3645 - Related articles - BL Direct - All 91 versions
DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
carry out a comprehensive investigation of the temporal program of gene expression accompanying
the metabolic shift from fermentation to respiration. The expression profiles observed for ...
Cited by 3645 - Related articles - BL Direct - All 91 versions
molbiolcell.org [HTML]… , MB Eisen, PO Brown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol
In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance
during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
regulated have been identified using traditional methods, and it was estimated that some ...
Cited by 3383 - Related articles - BL Direct - All 84 versions
In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance
during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
regulated have been identified using traditional methods, and it was estimated that some ...
Cited by 3383 - Related articles - BL Direct - All 84 versions
pnas.org [HTML]… JC Matese, PO Brown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences
The purpose of this study was to classify breast carcinomas based on variations in gene expression
patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three ...
Cited by 2902 - Related articles - BL Direct - All 31 versions
The purpose of this study was to classify breast carcinomas based on variations in gene expression
patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three ...
Cited by 2902 - Related articles - BL Direct - All 31 versions
molbiolcell.org [HTML]… , MB Eisen, G Storz, D Botstein, PO Brown - Molecular biology of …, 2000 - Am Soc Cell Biol
We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding
to diverse environmental transitions. DNA microarrays were used to measure changes in transcript
levels over time for almost every yeast gene, as cells responded to temperature shocks, ...
Cited by 2151 - Related articles - BL Direct - All 54 versions
We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding
to diverse environmental transitions. DNA microarrays were used to measure changes in transcript
levels over time for almost every yeast gene, as cells responded to temperature shocks, ...
Cited by 2151 - Related articles - BL Direct - All 54 versions
ctu.edu.vn [PDF]PO Brown, D Botstein - nature genetics, 1999 - ctu.edu.vn
The genome project has revitalized exploration in biological research. Not long ago, it was possible
for biologists to imagine that the genes that had been discovered via mutations, selections and
cloning schemes represented a good approximation of the total universe of genes, and ...
Cited by 1919 - Related articles - View as HTML - BL Direct - All 82 versions
The genome project has revitalized exploration in biological research. Not long ago, it was possible
for biologists to imagine that the genes that had been discovered via mutations, selections and
cloning schemes represented a good approximation of the total universe of genes, and ...
Cited by 1919 - Related articles - View as HTML - BL Direct - All 82 versions
stanford.edu [PDF]J DeRisi, L Penland, PO Brown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu
... microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita
Penland2 & Patrick О ... with significantly higher expression (>10-fold) in the tumorigenic cells was
the human brown locus pro ... Filters were washed to a strin- gency of O.lx SSC at 42 °C for 20 ...
Cited by 1699 - Related articles - BL Direct - All 9 versions
... microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita
Penland2 & Patrick О ... with significantly higher expression (>10-fold) in the tumorigenic cells was
the human brown locus pro ... Filters were washed to a strin- gency of O.lx SSC at 42 °C for 20 ...
Cited by 1699 - Related articles - BL Direct - All 9 versions
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