1.题目和摘要

Indicate  the study’s design with a commonly used term in the title or the abstract.  Provide an informative and balanced summary of what was done and what was  found in the abstract.

在题目或摘要中用常用术语表明研究所采用的设计；在摘要中对所做工作和获得的结果做简要的总结

2.引言/背景

Explain  the scientific background and rationale for the investigation being reported.

解释研究的科学背景和依据

3. 目的

State  objectives and hypothesis.

阐明研究目的和假设

4.方法–研究设计

Summarize  study design, study dates, location, and follow-up. For cohorts, give  eligibility details, selection methods, any matching, etc. Define outcomes  and confounders.

总结研究设计、研究日期、地点和随访。对于研究队列，给出纳入标准细节、选择方法、配对等等。定义结局和混杂因素

5. 研究设置

Give  setting, locations, and relevant dates (recruitment, treatment, follow-up).

描述研究机构、研究地点和相关日期（招募、治疗、随访）

6. 参与者

Eligibility;  case, control and rationale; and methods used to select study subjects.

纳入标准；病例、对照和依据；确认选择参与者的方法

7. 变量

Define  outcomes, exposures, predictors, modifiers, and diagnostic groups.

明确定义结局、暴露、预测因子、修饰因素和诊断组别

8. 数据

For  any variable, give source and how it was assessed.

对任何变量，给出来源和测量方法

9. 偏倚

Point  out sources of bias.

指出偏倚的来源

10.样本大小

Indicate  how study size was determined.

描述样本量的确定方法

11.定量变量

How  were these variables analyzed?

这些定量变量是如何分析的

12.统计方法

State  which type of statistics with details, controls, interactions, lost data  handling, matching, and sensitivity.

描述所用的统计方法，包含细节、对照、交互作用、丢失数据的处理方法、配对和灵敏性

13.结果–队列数量

Include  possible and final numbers enrolled; and explain loss of study participants, if  any.

包括可能和最终参与者的人数；并解释参与者退出研究的原因（如果有）

14.队列描述

Demographics,  social, cultural information, confounders and absent data.

描述人口统计、社会、文化信息、混杂因素和数据缺失情况

15.结局数据

Include  as appropriate for type of study.

包含适合研究类型的数据

16.主要结果

Unadjusted,  confounder adjusted with precision; note boundaries; absolute vs relative.

未校正的估计值、混杂因素校正后的估计值及其精确度；给出范围；绝对危险vs相对危险

17.其他分析

Subgroup  and/or sensitivity analyses can be included.

可以包含亚组和/或灵敏性分析

18.讨论–关键结果

Summary  of key findings.

概括关键结果

19.讨论–局限性

Limitations  of study should be addressed.

讨论研究的局限性

20.讨论–解释

Cautious  evaluation of study findings.

谨慎给出研究结果的总体解释

21.讨论–结论

Short  summary of primary findings.

主要结果的简要总结

22.其他信息–资金来源

Who  supported the work financially?

提供研究资金的来源