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诺奖文集 2015年诺贝尔医学奖 坎贝尔 爱尔兰科学家

已有 1360 次阅读 2022-9-17 06:55 |个人分类:诺贝尔奖|系统分类:论文交流



William C. Campbell is an Irish scientist. In October 2015, because Kazuo and Kimura discovered a new drug called avermectin, its derivative ivermectin fundamentally reduced the incidence rate of river blindness and elephantiasis. [1] Together with Youyou Tu and Zhi Omura, they won the 2015 Nobel Prize in Physiology or Medicine. [2]

威廉·C·坎贝尔(William C. Campbell),爱尔兰科学家。2015年10月,因为和大村智发现了一种名为阿维菌素的新药,其衍生物伊维菌素(ivermectin)从根本上降低了河盲症象皮病的发病率。 [1]  和屠呦呦大村智一起荣获2015年诺贝尔生理学或医学奖 [2]https://baike.baidu.com/item/%E5%A8%81%E5%BB%89%C2%B7C%C2%B7%E5%9D%8E%E8%B4%9D%E5%B0%94/18694851?fromModule=lemma_inlink




https://pubmed.ncbi.nlm.nih.gov/27243156/

summary-CampbellWC-set.txt




Review

 

Angew Chem Int Ed Engl

2016 Aug 22;55(35):10184-9.

 doi: 10.1002/anie.201601492. Epub 2016 May 31.

Ivermectin: A Reflection on Simplicity (Nobel Lecture)

William C Campbell 1

Affiliations expand

Abstract

Parasitic diseases including river blindness and lymphatic filariasis affect hundreds of millions of people annually. The discovery of the drug ivermectin has provided humankind with a powerful new means to combat these severe diseases. To a very large extent the drug was brought about by "simple" science.

Keywords: anthelmintic activity; ivermectin; medicinal chemistry; river blindness; worm infections.

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