||
Mary-Claire King
美国华盛顿大学医学和基因组科学教授
获奖原因:证明了乳腺癌和卵巢癌的遗传易感性,并发现了BRCA1基因突变所造成的影响。
https://news.sciencenet.cn/htmlnews/2022/9/486643.shtmDBZ
代表作
1. Systematic misclassification of missense variants in BRCA1 and BRCA2 "coldspots".
Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, WA, USA.
cpritch@uw.edu
Genet Med (P 1530-0366 E 1098-3600) H指数:111 2020 年 22 卷 5 期 825-830 页
PMID:31911673 相似文献
文摘 DOI链接 Elsevier ScienceElsevier ScienceEurope PubMed CentralPubMed Central
英
汉
2. Mechanism for survival of homozygous nonsense mutations in the tumor suppressor gene BRCA1.
Department of Medicine, University of Washington, Seattle, WA 98195.
mcking@uw.edu
Proc Natl Acad Sci U S A (P 1091-6490 E 0027-8424) H指数:699 2018 年 115 卷 20 期 5241-5246 页
PMID:29712865 相似文献
英
汉
Department of Biochemistry, University of Washington, Seattle, WA 98195.
mcking@u.washington.edu
Proc Natl Acad Sci U S A (P 1091-6490 E 0027-8424) H指数:699 2018 年 115 卷 6 期 1316-1321 页
PMID:29367421 相似文献
英
汉
Division of Medical Genetics, Department of Medicine, University of Washington, Seattle
JAMA Oncol (P 2374-2445 E 2374-2437) H指数:61 2017 年 3 卷 12 期 1647-1653 页
PMID:28727877 相似文献
文摘 DOI链接 Silverchair Information SystemsEurope PubMed CentralOvid Technologies, Inc.PubMed Central
英
汉
5. Precision medicine meets public health: population screening for BRCA1 and BRCA2.
Ephrat Levy-Lahad,Amnon Lahad,Mary-Claire King
Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel (ELL); Faculty of Medicine, Hebrew University Medical School, Jerusalem, Israel (ELL, AL); Department of Family Medicine, Clalit Health Services, Jerusalem, Israel (AL); Department of Medicine and Department of Genome Sciences, University of Washington, Seattle, WA (MCK). lahad@szmc.org.il.
lahad@szmc.org.il
J Natl Cancer Inst (P 1460-2105 E 0027-8874) H指数:333 2015 年 107 卷 1 期 420 页
PMID:25550384 相似文献
文摘 DOI链接 Silverchair Information SystemsOvid Technologies, Inc.
英
汉
6. Inherited predisposition to breast cancer among African American women.
Department of Medicine, Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.
Breast Cancer Res Treat (P 1573-7217 E 0167-6806) H指数:139 2015 年 149 卷 1 期 31-9 页
PMID:25428789 相似文献
英
汉
7. BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma.
Division of Gynecologic Oncology, University of Washington Medical Center, Seattle, Washington 98195-6460, USA.
Cancer (P 1097-0142 E 0008-543X) H指数:277 2013 年 119 卷 2 期 332-8 页
PMID:22811390 相似文献
文摘 DOI链接 WileyEurope PubMed CentralOvid Technologies, Inc.PubMed Central
英
汉
Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington 98195, USA.
Cancer Res (P 1538-7445 E 0008-5472) H指数:411 2011 年 71 卷 6 期 2222-9 页
PMID:21285249 相似文献
文摘 DOI链接 Silverchair Information SystemsEurope PubMed CentralPubMed Central
英
汉
9. Ten genes for inherited breast cancer.
Department of Medicine, University of Washington, Seattle, Washington 98195, USA. twalsh@u.washington.edu
twalsh@u.washington.edu
Cancer Cell (P 1535-6108 E 1535-6108) H指数:295 2007 年 11 卷 2 期 103-5 页
PMID:17292821 相似文献
英
汉
Department of Medicine, Division of Medical Genetics, University of Washington School of Medicine, Seattle, WA 98195-7720, USA.
Mol Cancer Res (P 1541-7786 E 1541-7786) H指数:124 2007 年 5 卷 1 期 35-45 页
PMID:17259345 相似文献
英
汉
11. BRCA1 transcriptionally regulates genes involved in breast tumorigenesis.
Department of Medicine and Genome Sciences, University of Washington, Health Sciences Room K-160, Seattle, WA 98195-7720, USA.
Proc Natl Acad Sci U S A (P 0027-8424 E 0027-8424) H指数:699 2002 年 99 卷 11 期 7560-5 页
PMID:12032322 相似文献
英
汉
12. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
P S Brzovic,P Rajagopal,D W Hoyt,M C King,R E Klevit
Department of Biochemistry and Biomolecular Structure Center, University of Washington, Seattle, Washington 98195-7742, USA.
Nat Struct Biol (P 1072-8368 E 1072-8368) H指数:0 2001 年 8 卷 10 期 833-7 页
PMID:11573085 相似文献
英
汉
Department of Medicine, University of California San Diego, La Jolla, CA 92093-0665, USA.
Proc Natl Acad Sci U S A (P 0027-8424 E 0027-8424) H指数:699 2001 年 98 卷 1 期 130-5 页
PMID:11136250 相似文献
英
汉
14. Complex germline rearrangement of BRCA1 associated with breast and ovarian cancer.
Department of Genetics, University of Washington, Seattle, Washington 98195, USA.
Genes Chromosomes Cancer (P 1045-2257 E 1045-2257) H指数:114 2000 年 29 卷 1 期 58-62 页
PMID:10918394 相似文献
英
汉
15. Prevalence of founder BRCA1 and BRCA2 mutations among breast and ovarian cancer patients in Hungary.
M Van Der Looij,C Szabo,I Besznyak,G Liszka,B Csokay,T Pulay,J Toth,P Devilee,M C King,E Olah
Department of Molecular Biology, National Institute of Oncology, Budapest, Hungary.
Int J Cancer (P 0020-7136 E 0020-7136) H指数:212 2000 年 86 卷 5 期 737-40 页
PMID:10797299 相似文献
英
汉
16. Insights into the functions of BRCA1 and BRCA2.
Departments of Medicine and Genetics, Box 357720, University of Washington, Seattle, WA 98195-7720, USA. piri@u.washington.edu
piri@u.washington.edu
Trends Genet (P 0168-9525 E 0168-9525) H指数:208 2000 年 16 卷 2 期 69-74 页
PMID:10652533 相似文献
英
汉
P S Brzovic,J Meza,M C King,R E Klevit
Department of Biochemistry and Biomolecular Structure Center, University of Washington, Seattle, Washington 98195-7742, USA.
J Biol Chem (P 0021-9258 E 0021-9258) H指数:477 1998 年 273 卷 14 期 7795-9 页
PMID:9525870 相似文献
英
汉
18. Founding BRCA1 mutations in hereditary breast and ovarian cancer in southern Sweden.
Department of Oncology, University Hospital, Lund, Sweden.
Am J Hum Genet (P 0002-9297 E 0002-9297) H指数:280 1996 年 58 卷 3 期 441-50 页
PMID:8644702 相似文献
英
汉
19. BRCA1 is secreted and exhibits properties of a granin.
Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-5310, USA.
Nat Genet (P 1061-4036 E 1061-4036) H指数:527 1996 年 12 卷 3 期 303-8 页
PMID:8589722 相似文献
英
汉
20. Growth retardation and tumour inhibition by BRCA1.
J T Holt,M E Thompson,C Szabo,C Robinson-Benion,C L Arteaga,M C King,R A Jensen
Department of Cell Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2175, USA.
Nat Genet (P 1061-4036 E 1061-4036) H指数:527 1996 年 12 卷 3 期 298-302 页
PMID:8589721 相似文献
http://www.pubmedplus.cn/P/SearchQuickResult?wd=f2a7cb45-13e1-4e64-90ab-066e9397b0bd
01. | 2020 | 1 篇 | 1.923% |
02. | 2018 | 2 篇 | 3.846% |
03. | 2017 | 2 篇 | 3.846% |
04. | 2016 | 1 篇 | 1.923% |
05. | 2015 | 3 篇 | 5.769% |
06. | 2014 | 1 篇 | 1.923% |
07. | 2013 | 1 篇 | 1.923% |
08. | 2011 | 3 篇 | 5.769% |
09. | 2010 | 1 篇 | 1.923% |
10. | 2007 | 2 篇 | 3.846% |
11. | 2006 | 3 篇 | 5.769% |
12. | 2003 | 1 篇 | 1.923% |
13. | 2002 | 1 篇 | 1.923% |
14. | 2001 | 3 篇 | 5.769% |
15. | 2000 | 4 篇 | 7.692% |
16. | 1998 | 4 篇 | 7.692% |
17. | 1997 | 3 篇 | 5.769% |
18. | 1996 | 6 篇 | 11.538% |
19. | 1995 | 3 篇 | 5.769% |
20. | 1994 | 5 篇 | 9.615% |
21. | 1993 | 2 篇 | 3.846% |
01. | am j hum genet | 8 篇 | 15.385% |
02. | proc natl acad sci u s a | 8 篇 | 15.385% |
03. | nat genet | 4 篇 | 7.692% |
04. | breast cancer res treat | 3 篇 | 5.769% |
05. | cancer res | 3 篇 | 5.769% |
06. | hum mol genet | 3 篇 | 5.769% |
07. | cancer | 2 篇 | 3.846% |
08. | int j cancer | 2 篇 | 3.846% |
09. | jama | 2 篇 | 3.846% |
10. | br j cancer | 1 篇 | 1.923% |
01. | 美国 | 43 篇 | 82.692% |
02. | 以色列 | 5 篇 | 9.615% |
03. | 巴西 | 1 篇 | 1.923% |
04. | 加拿大 | 1 篇 | 1.923% |
05. | 葡萄牙 | 1 篇 | 1.923% |
06. | 瑞典 | 1 篇 | 1.923% |
07. | 土耳其 | 1 篇 | 1.923% |
08. | 匈牙利 | 1 篇 | 1.923% |
09. | 英国 | 1 篇 | 1.923% |
10. | 智利 | 1 篇 | 1.923% |
没有聚类出数据 |
01. | Humans | 49 篇 | 94.231% |
02. | Female | 47 篇 | 90.385% |
03. | Breast Neoplasms | 41 篇 | 78.846% |
04. | Ovarian Neoplasms | 39 篇 | 75.000% |
05. | BRCA1 Protein | 27 篇 | 51.923% |
06. | Mutation | 25 篇 | 48.077% |
07. | Genetic Predisposition to Disease | 18 篇 | 34.615% |
08. | Neoplasm Proteins | 18 篇 | 34.615% |
09. | Transcription Factors | 18 篇 | 34.615% |
10. | Male | 17 篇 | 32.692% |
Archiver|手机版|科学网 ( 京ICP备07017567号-12 )
GMT+8, 2024-3-29 07:00
Powered by ScienceNet.cn
Copyright © 2007- 中国科学报社