Stuart H. Orkin

美国哈佛医学院David G. Nathan特聘儿科教授、霍华德·休斯医学研究所研究员

获奖原因：对血液病遗传基础展开基础性研究，以及推进镰状细胞贫血症和β－地中海贫血症的基因治疗

https://news.sciencenet.cn/htmlnews/2022/9/486643.shtm

代表作

• 1. Emerging Genetic Therapy for Sickle Cell Disease.

  
  

  Stuart H Orkin,Daniel E Bauer

  Dana Farber/Boston Children's Cancer and Blood Disorders Center, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA; email: Daniel.Bauer@childrens.harvard.edu.

  Daniel.Bauer@childrens.harvard.edu

  Annu Rev Med (P 1545-326X E 0066-4219) H指数：148 2019 年 70 卷 257-271 页

  PMID：30355263 相似文献

  文摘 DOI链接 Atypon

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  2. Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.

  
  

  Christian Brendel,Swaroopa Guda,Raffaele Renella,Daniel E Bauer,Matthew C Canver,Young-Jo Kim,Matthew M Heeney,Denise Klatt,Jonathan Fogel,Michael D Milsom,Stuart H Orkin,Richard I Gregory,David A Williams

  
  

  
  

  J Clin Invest (P 1558-8238 E 0021-9738) H指数：447 2016 年 126 卷 10 期 3868-3878 页

  PMID：27599293 相似文献

  文摘 DOI链接 American Society for Clinical InvestigationEurope PubMed CentralOvid Technologies, Inc.PubMed Central

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  3. Mathematical modeling of erythrocyte chimerism informs genetic intervention strategies for sickle cell disease.

  
  

  Philipp M Altrock,Christian Brendel,Raffaele Renella,Stuart H Orkin,David A Williams,Franziska Michor

  Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.

  
  

  Am J Hematol (P 1096-8652 E 0361-8609) H指数：92 2016 年 91 卷 9 期 931-7 页

  PMID：27299299 相似文献

  文摘 DOI链接 WileyEurope PubMed CentralOvid Technologies, Inc.PubMed Central

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  4. MEDICINE. Paying for future success in gene therapy.

  
  

  Stuart H Orkin,Philip Reilly

  Dana Farber Cancer Institute and Boston Children's Hospital, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA. stuart_orkin@dfci.harvard.edu philip@thirdrockventures.com.

  stuart_orkin@dfci.harvard.edu

  Science (P 1095-9203 E 0036-8075) H指数：1058 2016 年 352 卷 6289 期 1059-61 页

  PMID：27230368 相似文献

  文摘 DOI链接 AtyponOvid Technologies, Inc.

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  5. Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease.

  
  

  Megan D Hoban,Stuart H Orkin,Daniel E Bauer

  Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Department of Pediatrics, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA; and.

  
  

  Blood (P 1528-0020 E 0006-4971) H指数：426 2016 年 127 卷 7 期 839-48 页

  PMID：26758916 相似文献

  文摘 DOI链接 Elsevier ScienceElsevier ScienceSilverchair Information SystemsEurope PubMed CentralPubMed Central

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  6. 2014 William Allan Award: A hematologist's pursuit of hemoglobin genetics.

  
  

  Stuart H Orkin

  Dana Farber Cancer Institute - Boston Children's Hospital Cancer and Blood Disorders Center, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA 02215, USA. Electronic address: stuart_orkin@dfci.harvard.edu.

  stuart_orkin@dfci.harvard.edu

  Am J Hum Genet (P 1537-6605 E 0002-9297) H指数：280 2015 年 96 卷 3 期 354-60 页

  PMID：25748351 相似文献

  文摘 DOI链接 Elsevier ScienceElsevier ScienceEurope PubMed CentralPubMed Central

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