SJ Benkovic, S Hammes-Schiffer - Science, 2003 - sciencemag.org The seminal hypotheses proposed over the years for enzymatic catalysis are scrutinized. The historical record is explored from both biochemical and theoretical perspectives. Particular attention is given to the impact of molecular motions within the protein on the enzyme's catalytic ... Cited by 341 - Related articles - All 10 versions