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Start A-Literature C-Literature B-list Filter Literature

A-query: cancer therapy C-query: matrix metalloproteinase inhibitors The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 897 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 30844 and can be accessed from the start page after you leave this session. There are 1391 terms on the current B-list (658 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

job id # 30844 started Tue Dec 28 01:30:11 2010
Max_citations: 50000
Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
30844 Search ARROWSMITH A
A_query_raw: cancer therapy Tue Dec 28 01:31:01 2010

A query = cancer therapy started Tue Dec 28 01:31:01 2010
A query resulted in 50000 titles
30844 Search ARROWSMITH C
C_query_raw: matrix metalloproteinase inhibitors Tue Dec 28 01:31:12 2010

C: matrix metalloproteinase inhibitors 11118

A: pubmed_query_A 327242

AC: ( cancer therapy ) AND ( matrix metalloproteinase inhibitors ) 897

C query = matrix metalloproteinase inhibitors started Tue Dec 28 01:31:13 2010
C query resulted in 11118 titles
A AND C query resulted in 897 titles
18686 B-terms ready on Tue Dec 28 01:34:15 2010

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
1391 B-terms left after filter executed Tue Dec 28 01:45:40 2010

B-list on Tue Dec 28 01:47:44 2010
1 endostatin
2 adiponectin
3 cox-2
4 toll receptor
5 rankl
6 jnk
7 wnt
8 jak2
9 akt
10 vegf
11 k ras
12 mek1
13 jak stat
14 single nucleotide polymorphism
15 mtor
16 stat3
17 erk1
18 angiopoietin-2
19 c jun n
20 cd147
21 p38 mapk
22 vegfr-2
23 amphiregulin
24 beta catenin
25 smad
26 caspase-3
27 ppargamma
28 signal regulated kinase
29 caspase
30 cyclin dependent kinase
31 emmprin
32 phosphatidylinositol 3-kinase
33 egr-1
34 pi3k
35 ets
36 her2
37 nk4
38 rho kinase
39 ctgf
40 sp1
41 janus kinase
42 cxcr4
43 pten
44 her-2
45 map kinase
46 metastasis suppressor
47 stat5
48 survivin
49 timp-1
50 estrogen receptor alpha
51 mt1-mmp
52 adam9
53 tissue inhibitor metalloproteinase
54 microrna
55 flt1
56 cannabinoid receptor
57 nkg2d
58 c jun
59 clusterin
60 cxcl8
61 syk
62 microsatellite
63 cd40
64 il-12
65 mek
66 fasl
67 runx2
68 statin
69 p27
70 tumstatin
71 cyclin d1
72 angiopoietin
73 jak
74 her-2 neu
75 matrix metalloproteinase
76 nm23-h1
77 fgfr2
78 autotaxin
79 cd40 ligand
80 endostatin gene
81 comfa
82 mmp-2
83 e cadherin
84 adenovirus mediated gene
85 ikappab
86 galectin-3
87 eralpha
88 erbb2
89 foxo3a
90 il-18
91 vegf a
92 cdk4
93 erbb-2
94 vegfr2
95 disintegrin
96 mmp-9
97 metabolic syndrome
98 integrin alpha v
99 aromatase
100 oncostatin m
101 adam10
102 c met
103 cd40l
104 bcl-2
105 integrin alpha
106 estrogen receptor beta
107 gsk-3beta
108 p38
109 progesterone receptor
110 xiap
111 chemokine
112 nf kappab
113 calcium sensing receptor
114 receptor tyrosine kinase
115 metastasis suppressor gene
116 adenoviral gene
117 promoter polymorphism
118 cd44
119 bax
120 endoglin
121 psa
122 p42
123 vegi
124 furin
125 sdf-1
126 cox2
127 s100a8
128 promoter hypermethylation
129 ikk
130 c flip
131 stat-3
132 ppar gamma
133 jnk1
134 decorin
135 chemokine receptor
136 ox40
137 c src
138 il-10
139 ppar
140 tgfbeta
141 caveolin-1
142 histone deacetylase
143 il-6
144 p70s6k
145 b16
146 th1
147 inos
148 notch1
149 cd34
150 hepatocyte growth factor
151 hur
152 cadherin
153 pai-1
154 tlr
155 il-15
156 rnai
157 trpv1
158 ap-1
159 rac1
160 rhoa
161 promoter methylation
162 stat1
163 pkcdelta
164 nf kappa b
165 erbb
166 raf-1
167 bcr abl
168 mmp2
169 ck2
170 telomerase reverse transcriptase
171 integrin linked kinase
172 ret transgenic
173 rheumatoid arthritis synovial
174 galectin-1
175 pkc
176 il-21
177 egfr signaling
178 axl
179 muc1
180 abl
181 alpha2b
182 aav
183 cll
184 catalytic domain
185 hmgb1
186 transcription factor
187 cytosolic phospholipase a2
188 gene breast
189 fak
190 notch-1
191 retinoic acid receptor
192 eif4e
193 hsp90
194 ets-1
195 ikkalpha
196 cpg
197 inflammatory bowel disease
198 synovial fibroblast
199 cd20
200 upar
201 src
202 pi3 kinase
203 reck
204 cd163
205 hif-1alpha
206 tweak
207 promoter activity
208 egfr
209 cxcl12
210 autophagy
211 erk
212 endothelin
213 leptin
214 cxcr3
215 erbeta
216 tyrosine kinase
217 wnt5a
218 tgf beta1
219 gene breast cancer
220 tgf beta
221 cyclin
222 toll
223 tnfalpha
224 angiotensin receptor
225 rhoc
226 nfat
227 aryl hydrocarbon receptor
228 yb-1
229 fhit
230 sirt1
231 her2 neu
232 egfr antibody
233 calreticulin
234 gene silencing
235 pdgfr
236 bone morphogenetic protein
237 il-8
238 expression gene
239 il-1beta
240 hmg coa reductase
241 nrf2
242 c ebp
243 hb egf
244 differentially expressed gene
245 ret
246 myd88
247 anti egfr
248 dlc1
249 jun
250 cyp3a
251 pten gene
252 heparan sulfate proteoglycan
253 anti egfr antibody
254 foxm1
255 nm23
256 metastatic gene
257 scfv
258 ubiquitin
259 estrogen receptor
260 n cadherin
261 cytokine gene
262 bcr
263 cell cycle progression
264 hcc
265 cathepsin l
266 dna methyltransferase
267 mkp-1
268 hsp70
269 p53 gene
270 il-13
271 gitr
272 cdk5
273 glycogen synthase
274 cdc25a
275 ctl
276 sparc
277 bcl
278 gm csf
279 annexin
280 h ras
281 cd151
282 tumor suppressor
283 topoisomerase
284 akt pkb
285 abl kinase
286 p21
287 nude
288 s100a4
289 ret transgenic mice
290 tnf alpha
291 kruppel factor
292 fli1
293 copd
294 ccr5
295 mmp-1
296 iiia
297 myc
298 reelin
299 bmp
300 adrenomedullin
301 cyr61
302 cd82
303 hyaluronan synthase
304 il-1
305 jak1
306 foxp3
307 egf
308 timp
309 marck
310 pkb
311 p53
312 cd8
313 parp
314 grape
315 hdac
316 lysyl oxidase
317 androgen receptor
318 creb
319 notch
320 upa
321 p65
322 neu
323 promoter demethylation
324 gene promoter
325 synergistic effect rapamycin
326 metalloprotease
327 yy1
328 growth factor gene
329 nur77
330 fgf
331 trail
332 sphingosine kinase
333 oncogene
334 gene transfection
335 fractalkine
336 adenoviral mediated gene
337 il-17
338 mta1
339 mda
340 flt-1
341 cdna
342 epha2
343 raf
344 ep4
345 c myc
346 endo180
347 genome wide
348 bfgf
349 vitamin d receptor
350 promyelocytic leukemia
351 icam-1
352 heparanase
353 egf r
354 inhibition egfr
355 cd16
356 extracellular matrix protein
357 odn
358 sonic hedgehog
359 flk-1
360 leukemia inhibitory factor
361 klf6
362 igf-1
363 notch4
364 cd9
365 dr5
366 heat shock protein
367 egfr mediated
368 gastrin releasing peptide
369 fgf receptor
370 tnf
371 g csf
372 u87
373 janus
374 cd13
375 transcription factor ets-1
376 epidermal growth factor
377 tgf alpha
378 hes1
379 tumor suppressor gene
380 e selectin
381 related gene
382 cytokine
383 rhamm
384 casein kinase
385 ccn1
386 proteoglycan
387 integrin
388 decoy
389 ifn
390 interferon alpha
391 tyrosine phosphatase
392 c jun nh2-terminal
393 cinc-1
394 gene transfer
395 exon
396 shp-1
397 connexin
398 sapk
399 candidate gene
400 pi3
401 claudin-1
402 il-1ra
403 thrombospondin
404 retinoblastoma
405 mri
406 fibroblast activation protein
407 id-1
408 promoter a
409 transgene
410 nadph oxidase
411 anaplastic lymphoma kinase
412 erk2
413 protein tyrosine phosphatase
414 hgf
415 retinoic acid induced
416 insulin growth factor
417 nf
418 synovial
419 il-7
420 rg3
421 pet
422 ephrin
423 cerebral cavernous malformation
424 timp2
425 cathepsin b
426 gene human breast
427 role egfr
428 syndecan-4
429 cb1
430 trkb
431 epha1
432 pcdgf
433 tumor necrosis factor
434 ccl2
435 pc3
436 adam17
437 alfa
438 caga
439 serum amyloid a
440 pkc delta
441 vpr
442 e7
443 protein kinase b
444 metalloproteinase-2 gene
445 g1
446 expression synovial
447 tie2
448 protein kinase
449 nk
450 fibronectin
451 histone acetyltransferase
452 erbb1
453 laminin receptor
454 experimental autoimmune myocarditis
455 galectin
456 growth regulated oncogene
457 retinoblastoma protein
458 jab1
459 promoter
460 cxcl11
461 serum response factor
462 trefoil factor
463 serine protease inhibitor
464 lyn
465 lc
466 cd27
467 il-2
468 frizzled related protein
469 th2
470 nef
471 glioma
472 tenascin c
473 igf ir
474 igf
475 t bet
476 neurotrophin
477 gp130
478 jnk2
479 metalloproteinase gene
480 kdr
481 adam
482 activin
483 tsp-1
484 repressor
485 annexin a2
486 pdt
487 il-6r
488 plasminogen
489 tnfr1
490 ib
491 matrix metalloproteinase gene
492 vegf gene
493 bnp
494 stat
495 gene human prostate
496 adam12
497 cathepsin
498 apc
499 macrophage activation
500 metastasis associated gene
501 cited2
502 gnrh
503 camkii
504 activating transcription factor
505 bone mineral density
506 meningioma
507 cell synergistic
508 guanylyl cyclase
509 parp-1
510 moyamoya disease
511 gene encoding
512 pkcepsilon
513 mmp13
514 desmoglein
515 trk
516 pyk2
517 ykl-40
518 tie-2
519 mdx
520 oxide synthase gene
521 cd45
522 cytokine production
523 inflammatory gene
524 aib1
525 sp1 transcription factor
526 genomic
527 interleukin
528 igf-1r
529 foxo1a
530 expression promoter
531 interleukin receptor
532 cd14
533 acrosin
534 gata-3
535 igf i
536 9l
537 prostate cancer
538 protein tyrosine kinase
539 ifn beta
540 protein kinase c
541 lipocalin
542 tea
543 click
544 p75
545 a2a
546 ing4
547 analysis gene
548 wilm tumor
549 lxr
550 gonadotropin releasing hormone
551 cd95l
552 ror2
553 fas
554 lrp5
555 iib
556 rt
557 senescence
558 glucocorticoid receptor
559 tumor suppression
560 rhogtpase
561 terminal repeat
562 rho
563 metallothionein
564 histone
565 matrix metalloproteinase-2 gene
566 gene matrix metalloproteinase
567 gene patient
568 tcf
569 tace
570 p300
571 e7 gene
572 hsp27
573 mmp
574 receptor kinase
575 enhancer
576 gene microrna
577 adam-10
578 fibroblast growth factor
579 node
580 metastasis associated
581 cystatin c
582 lpa
583 cathepsin k
584 cell adhesion molecule
585 ifn gamma
586 defensin
587 emt
588 laminin
589 neuregulin
590 wnt1
591 ifn alpha
592 met signaling promote
593 prognostic value e
594 il-4
595 thymoma
596 3d
597 thymosin
598 kit
599 ro
600 elastin
601 tat
602 trka
603 sp3
604 cd26
605 ep2
606 wnt3a
607 heat shock factor
608 thrombopoietin
609 a4
610 crp
611 reduced expression
612 nucleophosmin
613 dr4
614 intron
615 suppressor gene
616 fret
617 hedgehog
618 rante
619 cathepsin s
620 bmp-2
621 junb
622 ca1
623 c6
624 immediate early gene
625 transferrin receptor
626 chaperone
627 novel gene
628 gene expressed
629 ep3
630 versican
631 factor gene
632 beta3
633 cd99
634 killer
635 jak3
636 scid
637 calpain
638 cortactin
639 erythropoietin
640 ornithine decarboxylase
641 inducible
642 tetraspanin
643 beta1
644 cystatin
645 cathepsin g
646 bcr abl induced
647 domain
648 carbonic anhydrase
649 adam15
650 snp
651 gene human
652 gene matrix
653 ldl
654 retroviral gene
655 cd4
656 serpin
657 pro opiomelanocortin
658 gtpase

Start A-Literature C-Literature B-list Filter Literature

AB literature   B-term   BC literature   cancer therapy rankl matrix metalloproteinase inhib... 1: Combined therapy with the RANKL inhibitor RANK-Fc and rhApo2L/TRAIL/dulanermin reduces bone lesions and skeletal tumor burden in a model of breast cancer skeletal metastasis. 2010 Add to clipboard 2: Targeting RANK/RANKL in the treatment of solid tumours and myeloma. 2010 Add to clipboard 3: Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. 2010 Add to clipboard 4: Combined Inhibition of the BMP pathway and the RANK-RANKL axis in a Mixed Lytic/blastic Prostate Cancer Lesion. 2010 Add to clipboard 5: Influence of simultaneous targeting of the bone morphogenetic protein pathway and RANK/RANKL axis in osteolytic prostate cancer lesion in bone. 2009 Add to clipboard 6: Zerumbone abolishes RANKL-induced NF-kappaB activation, inhibits osteoclastogenesis, and suppresses human breast cancer-induced bone loss in athymic nude mice. 2009 Add to clipboard 7: RANKL/RANK as key factors for osteoclast development and bone loss in arthropathies. 2009 Add to clipboard   1: IL-17 induces myocardial fibrosis and enhances RANKL/OPG and MMP/TIMP signaling in isoproterenol-induced heart failure. 2009 Add to clipboard 2: Poly(adp-ribose) polymerase-1 regulates Tracp gene promoter activity during RANKL-induced osteoclastogenesis. 2008 Add to clipboard 3: The synthetic triterpenoid TP-222 inhibits RANKL stimulation of osteoclastogenesis and matrix metalloproteinase-9 expression. 2007 Add to clipboard 4: Water extract of Cordyceps sinensis (WECS) inhibits the RANKL-induced osteoclast differentiation. 2007 Add to clipboard 5: Cytokine pattern determines the progression of experimental periodontal disease induced by Actinobacillus actinomycetemcomitans through the modulation of MMPs, RANKL, and theirphysiological inhibitors. 2006 Add to clipboard 6: mu-Calpain regulates receptor activator of NF-kappaB ligand (RANKL)-supported osteoclastogenesis via NF-kappaB activation in RAW 264.7 cells. 2005 Add to clipboard 7: RANKL and vascular endothelial growth factor (VEGF) induce osteoclast chemotaxis through an ERK1/2-dependent mechanism. 2003 Add to clipboard

 

 

 

 

 

 

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