文章:An ORFome assembly approach to metagenomics sequences analysis 杂志:J Bioinform Comput Biol 年份:2009 宏基因组组装的挑战: 1) metagenomics projects often apply NGS technique, and produce shorter reads . As a result, many short repeats may increase the complexity of t ...
文章: Metagenomic Pyrosequencing and Microbial Identification 杂志: Clin Chem 年份:2009 80% of bacteria identified by metagenomic sequencing were considered noncultivable.(80%的菌是不能体外培养的) Pathogen identification in infectious diseases relies mostly on routine c ...
文章: Statistical Methods for Detecting Differentially Abundant Features in Clinical Metagenomic Samples 杂志 : PLoS Comput Biol. 年份:2009 原始数据: 数据格式如下,其中具体的值可以是任何要分析的值。原文描述是 the relative abundance of specific features ...
文章: Ethical, legal, and social considerations in conducting the Human Microbiome Project 杂志:Genome Research 讨论了HMP计划的伦理、法律等方面的问题; 样品收集,用了排除法,原则是有可能影响肠道菌群稳定的情况进行了排除: 1) taking specific medications (e.g., antibiotics, immunosuppr ...
文章: Ganoderma lucidum reduces obesity in mice bymodulating the composition of the gut microbiota 杂志:Nature Communication 研究方案: 1)8周龄的小鼠随机分成6组,每组5-7只小鼠;分别是正常饮食(chow)、正常饮食加8%的灵芝水提物(chow+8%WEGL)、高脂饮食(HFD)、高脂饮食加2 ...