上个80年代由Weinberg提出基因突变致癌的理论始终是癌症研究的主流。但是近年来细胞转化的进展一日千里,人们终于发现如果从受精卵到神经细胞,心脏细胞等等的复杂变化引起的细胞分化不需要基因突变的话,为什么癌症的细胞变化就只盯着基因突变呢? 今天的《细胞》杂志发表了无基因突变的癌症的产生,无疑是Cancer Att ...
Sydney Brenner is one of pioneers of molecular biology with Watson and Crick. He involved in coding problem, gene network for development of C. Elegan, genome sequencing and comparative genomics. This is the talk which he gave in TATA institute of theoretical study, which revealed his insight on t ...