Ten simple rules towards healthier research labs 让实验室运行更加健康与快乐的十条准则 作者：Fernando T. Maestre, 2019 Maestre教授认为， 在竞争激烈的学术环境中， 快乐、善良和谦逊的力量被低估了，他坚信它们是一种有利于科学实践的变革力量 。 Maestre认为，科研工作和生活可以更好地平衡，这些原则 ...
Title: Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro Published in Emerging Microbes Infections on January 06, 2022 Abstract: Coronavirus disease 2019 (COVID-19) caused by the emerging seve ...
题目Title: Reduced neutralization of SARS-CoV-2 B.1.617 variant by convalescent and vaccinated sera 共同第一作者Co-first author: Jie Hu (胡杰)、Xiao-yu Wei（魏晓宇）、Jin Xiang（向进） 摘要Abstract: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory sy ...
《 Frontiers in Cellular and Infection Microbiology 》 本期特刊 Metabolic Rewiring and Viral Infection 专题 简介 About this Research Topic Viruses are intracellular pathogens that rely on hijacking host resources to complete their life cycle. Specifically, upon infect ...
课题组今年2月在CMI期刊发表的新冠病毒阿尔法（B.1.1.7）和贝塔(B.1.351) 突变株 的文章入选ESI高被引论文。 Jie Hu # , Pai Peng # , Kai Wang # , Liang Fang, Fei-yang Luo, Ai-shun Jin, Bei-zhong Liu*, Ni Tang*, Ai-long Huang*, Emerging SARS-CoV-2 variants reduce neutralization sen ...
课题组在爱思唯尔（ Elsevier ）金色开放获取（ OA ）期刊 Genes Diseases 上发表的文章 Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-2 上线后一年内的全球总下载量居前列，在同季度 生命科学 中国作者论 ...
O-GlcNAc modified-TIP60/KAT5 is required for PCK1 deficiency-induced HCC metastasis 摘要： Aberrant glucose metabolism and elevated O-linked β- N-acetylglucosamine modification (O-GlcNAcylation) are hallmarks of hepatocellular carcinoma (HCC). Loss of phosphoenolpyruvate carboxykinase 1 ( ...
2021 年 9 月 5 日，中国科学院王祥喜团队与北京大学、复旦大学、中国食品和药品检定研究院、广州实验室、广东省疾病预防控制中心、浙江省疾病预防控制中心以及科兴生物（ SINOVAC 科兴）合作在 medRxiv 上发表题为 “ A third dose of inactivated vaccine augments the potency, breadth, and dura ...
在疫苗诱导的免疫和自然感染诱导的机体免疫反应中，细胞免疫和体液免疫在清除 SARS-CoV-2 和防止新冠病毒再感染方面的相对贡献仍然不明确。The relative contributions of cellular and humoral immunity in the clearance of SARS-CoV-2 and protection from reinfection remain poorly defined in both vaccine-i ...
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