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JANEWANGJK55 发表了评论   2019-3-26 05:44
2019-03-26
5:00am wake up   开始早起工作模式
JANEWANGJK55 发表了评论   2019-4-11 17:29
https://pubmlst.org/bigsdb?db=pubmlst_ecoli_achtman_seqdef&set_id=4&page=batchSequenceQuery
JANEWANGJK55 发表了评论   2019-4-11 17:32
https://pubmlst.org/escherichia/
JANEWANGJK55 发表了评论   2019-4-11 17:32
https://pubmlst.org/bigsdb?db=pubmlst_rmlst_seqdef_kiosk  
Identified species
JANEWANGJK55 发表了评论   2019-4-11 17:34
https://pubmlst.org/databases.shtml
JANEWANGJK55 发表了评论   2019-6-10 15:56
T, from the whole-genome sequence data of ESBL-EC submitted to the NCBI database, over 75% of isolates carried mcr-1within the CTX-M-55–positive ESBL-EC, which was much higher than other CTX-M type isolates.he high diversity of sequence-type clades of mcr-1-harboring strains further confirms the wide distribution of mcr-1-carrying E. coli and the colistin resistance is mediated mainly by plasmids rather than adapted dominant bacterial clones (Shen et al., 2018a). Such phenomena may be attributed to the co-selection of antibiotic resistance caused by improper combination usage of multiple classes of broad-spectrum antibiotics. The presence of these multiple drug resistance phenotypes further indicated that the co-existence of ESBLs with other resistance genes in E. coli strains results in an expansion of their resistance spectrum to β-lactam antibiotics or to other antibiotics, which poses a serious challenge to the application of antibiotics in the poultry industry. Therefore, ESBL-EC may be used as an indicator for the surveillance of multiple-drug-resistant E. coli in food animal production.  …..Recently https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849743/ The co-rising of the ESBL-EC and MECPEC can be traced back to 2008 from this study, which is highly synchronized with the rapid growth of veterinary drug consumption, especially of amoxicillin/clavulanic acid and colistin, in the poultry industry.
JANEWANGJK55 发表了评论   2019-8-2 13:07
QXGO01000080            1329 bp
QXGO01000090             612 bp
QXGO01000093             510 bp
QXGO01000094             444 bp
QXGO01000095             443 bp
QXGO01000100             415 bp



QXGP01000001          219119 bp
QXGP01000100            4414 bp  



QXGP01000200             227 bp  
QXGP01000150             660 bp
QXGP01000152             556 bp
QXGP01000153             555 bp
QXGP01000155             509 bp
QXGP01000156             490 bp


NZ_QUON01000001  QUON01000001  QUON01000107
QUOM01000001    QUOM01000089  







https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA480178
JANEWANGJK55 发表了评论   2019-8-2 13:39
F81 (QXGP01000001 to QXGP01000155), F89 (QXGO01000001 to QXGO01000093), Dog1 (QUON01000001 to QUON01000107) and CY69 (QUOM01000001 to QUOM01000089).
JANEWANGJK55 发表了回复   2020-7-14 10:18
中巴(两国)畜禽重要病原菌耐药性检测与控制技术研究

规模猪场养殖环境中耐药质粒多态性及转移机制研究
JANEWANGJK55 发表了回复   2021-10-18 16:01
, more C. perfringens isolates from sheep were positive for toxin gene cpb2
JANEWANGJK55 发表了回复   2021-10-20 15:42
回复王娟养殖业广泛使用甚至滥用抗菌药,也造成了畜禽病原菌的耐药率快速上升,耐药水平越来越高,耐药谱越来越广,这使我国成为世界上畜禽病原菌耐药性最严重的国家之一。
动物源细菌耐药性问题不仅影响我国养殖业持续健康发展,也威胁着公众健康。
长期以来,抗菌药为畜牧业的健康发展一直起着保驾护航的重要作用,并且在将来较长时期内,抗菌药仍是集约化养殖业防治细菌病的主要手段。但随着抗菌药在养殖业的广泛使用,耐药菌的出现有可能使人类重新回到对多种感染无药可用的“前抗生素”黑暗时代,抗菌药的耐药性逐渐发展成为全球面临的挑战性问题。
进入21世纪以来,多种病原菌对抗菌药产生了耐药、多重耐药、泛耐药甚至全耐药现象,给人医和兽医临床带来巨大挑战。我国是畜禽养殖大国,也是兽用抗菌药物生产和使用大国。抗菌药在我国畜牧业的可持续发展中功不可没。与此同时,养殖业广泛使用甚至滥用抗菌药,也造成了畜禽病原菌的耐药率快速上升,耐药水平越来越高,耐药谱越来越广,这使我国成为世界上畜禽病原菌耐药性最严重的国家之一。如果不加以控制,细菌耐药性问题不仅会影响我国畜牧业的可持续健康发展,也将会给食品安全、人类健康、公共卫生方面也带来一系列的危害。

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