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- JANEWANGJK55
- https://pubmlst.org/bigsdb?db=pubmlst_ecoli_achtman_seqdef&set_id=4&page=batchSequenceQuery
- JANEWANGJK55
- https://pubmlst.org/bigsdb?db=pubmlst_rmlst_seqdef_kiosk
Identified species
- JANEWANGJK55
- T, from the whole-genome sequence data of ESBL-EC submitted to the NCBI database, over 75% of isolates carried mcr-1within the CTX-M-55–positive ESBL-EC, which was much higher than other CTX-M type isolates.he high diversity of sequence-type clades of mcr-1-harboring strains further confirms the wide distribution of mcr-1-carrying E. coli and the colistin resistance is mediated mainly by plasmids rather than adapted dominant bacterial clones (Shen et al., 2018a). Such phenomena may be attributed to the co-selection of antibiotic resistance caused by improper combination usage of multiple classes of broad-spectrum antibiotics. The presence of these multiple drug resistance phenotypes further indicated that the co-existence of ESBLs with other resistance genes in E. coli strains results in an expansion of their resistance spectrum to β-lactam antibiotics or to other antibiotics, which poses a serious challenge to the application of antibiotics in the poultry industry. Therefore, ESBL-EC may be used as an indicator for the surveillance of multiple-drug-resistant E. coli in food animal production. …..Recently https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849743/ The co-rising of the ESBL-EC and MECPEC can be traced back to 2008 from this study, which is highly synchronized with the rapid growth of veterinary drug consumption, especially of amoxicillin/clavulanic acid and colistin, in the poultry industry.
- JANEWANGJK55
- QXGO01000080 1329 bp
QXGO01000090 612 bp
QXGO01000093 510 bp
QXGO01000094 444 bp
QXGO01000095 443 bp
QXGO01000100 415 bp
QXGP01000001 219119 bp
QXGP01000100 4414 bp
QXGP01000200 227 bp
QXGP01000150 660 bp
QXGP01000152 556 bp
QXGP01000153 555 bp
QXGP01000155 509 bp
QXGP01000156 490 bp
NZ_QUON01000001 QUON01000001 QUON01000107
QUOM01000001 QUOM01000089
https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA480178
- JANEWANGJK55
- F81 (QXGP01000001 to QXGP01000155), F89 (QXGO01000001 to QXGO01000093), Dog1 (QUON01000001 to QUON01000107) and CY69 (QUOM01000001 to QUOM01000089).
- JANEWANGJK55
- 回复王娟养殖业广泛使用甚至滥用抗菌药，也造成了畜禽病原菌的耐药率快速上升，耐药水平越来越高，耐药谱越来越广，这使我国成为世界上畜禽病原菌耐药性最严重的国家之一。
动物源细菌耐药性问题不仅影响我国养殖业持续健康发展，也威胁着公众健康。
长期以来，抗菌药为畜牧业的健康发展一直起着保驾护航的重要作用，并且在将来较长时期内，抗菌药仍是集约化养殖业防治细菌病的主要手段。但随着抗菌药在养殖业的广泛使用，耐药菌的出现有可能使人类重新回到对多种感染无药可用的“前抗生素”黑暗时代，抗菌药的耐药性逐渐发展成为全球面临的挑战性问题。
进入21世纪以来，多种病原菌对抗菌药产生了耐药、多重耐药、泛耐药甚至全耐药现象，给人医和兽医临床带来巨大挑战。我国是畜禽养殖大国，也是兽用抗菌药物生产和使用大国。抗菌药在我国畜牧业的可持续发展中功不可没。与此同时，养殖业广泛使用甚至滥用抗菌药，也造成了畜禽病原菌的耐药率快速上升，耐药水平越来越高，耐药谱越来越广，这使我国成为世界上畜禽病原菌耐药性最严重的国家之一。如果不加以控制，细菌耐药性问题不仅会影响我国畜牧业的可持续健康发展，也将会给食品安全、人类健康、公共卫生方面也带来一系列的危害。
