近期病毒免疫学领域的一些有趣的文献，有些具有很强的启发性！有些我也没有来得及精读，留在这里慢慢看吧。其中有一篇是我自己的，算自卖自夸吧。

Teijaro JR, Ng C, Lee AM, Sullivan BM, Sheehan KC, Welch M, Schreiber RD, de la Torre JC, Oldstone MB. Persistent LCMV infection is controlled by blockade of type I interferon signaling. Science. 2013 Apr 12;340(6129):207-11. doi: 10.1126/science.

Li, J., Liu, K., Liu, Y., Xu, Y., Zhang, F., Yang, H., Liu, J., et al. (2013). Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity. Nature Immunology, 14(8), 793–803. doi:10.1038/ni.2647

Python S, Gerber M, Suter R, Ruggli N, Summerfield A. Efficient Sensing of Infected Cells in Absence of Virus Particles by Blasmacytoid Dendritic Cells Is Blocked by the Viral Ribonuclease  E(rns.). PLoS Pathog. 2013 Jun;9(6):e1003412. doi: 10.1371/journal.ppat.1003412. Epub  2013 Jun 13.

Schlesinger S, Lee AH, Wang GZ, Green L, Goff SP. (2013) Proviral Silencing in Embryonic Cells Is Regulated by Yin Yang 1. Cell Rep. 2013 Jun 26. pii: S2211-1247(13)00279-9. doi: 10.1016/j.celrep.2013.06.003. [Epub ahead of print]

Xu, Z., Qiu, Q., Tian, J., Smith, J.S., Conenello, G.M., Morita, T., and Byrnes, A.P. (2013). Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement. Nat Med 19, 452–457.

Weekes MP, Tan SY, Poole E, Talbot S, Antrobus R, Smith DL, Montag C, Gygi SP, Sinclair JH, Lehner PJ. (2013) Latency-associated degradation of the MRP1 drug transporter during latent human cytomegalovirus infection. Science Apr 12;340(6129):199-202

Lusic, M., Marini, B., Ali, H., Lucic, B., Luzzati, R., & Giacca, M. (2013). Proximity to PML Nuclear Bodies Regulates HIV-1 Latency in CD4+ T Cells. Cell Host and Microbe, 13(6), 665–677. Elsevier Inc. doi:10.1016/j.chom.2013.05.006

Cooper, A., García, M., Petrovas, C., Yamamoto, T., Koup, R. A., & Nabel, G. J. (2013). HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration. Nature. doi:10.1038/nature12274

Diner, E. J., Burdette, D. L., Wilson, S. C., Monroe, K. M., Kellenberger, C. A., Hyodo, M., Hayakawa, Y., et al. (2013). The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING. CellReports, 3(5), 1355–1361. The Authors. doi:10.1016/j.celrep.2013.05.009

Amini-Bavil-Olyaee, S., Choi, Y.J., Lee, J.H., Shi, M., Huang, I.-C., Farzan, M., and Jung, J.U. (2013). The Antiviral Effector IFITM3 Disrupts Intracellular Cholesterol Homeostasis to Block Viral Entry. Cell Host Microbe 13, 452–464.

Bitzegeio, J., Sampias, M., Bieniasz, P.D., and Hatziioannou, T. (2013). Adaptation to the IFN-induced antiviral state by human and simian immunodeficiency viruses. Journal of Virology.

Dai, L., Lidie, K.B., Chen, Q., Adelsberger, J.W., Zheng, X., Huang, D., Yang, J., Lempicki, R.A., Rehman, T., Dewar, R.L., et al. (2013). IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation. J Exp Med 210, 517–534.

Feng, Z., Hensley, L., McKnight, K.L., Hu, F., Madden, V., Ping, L., Jeong, S.-H., Walker, C., Lanford, R.E., and Lemon, S.M. (2013). A pathogenic picornavirus acquires an envelope by hijacking cellular membranes. Nature 496, 367–371.

Ferguson, B.J., Mansur, D.S., Peters, N.E., Ren, H., and Smith, G.L. (2012). DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. eLife 1, e00047–e00047.

Galão, R.P., Le Tortorec, A., Pickering, S., Kueck, T., and Neil, S.J.D. (2012). Innate Sensing of HIV-1 Assembly by Tetherin Induces NFκB-Dependent Proinflammatory Responses. Cell Host Microbe 12, 633–644.

Hasan, M., Koch, J., Rakheja, D., Pattnaik, A.K., Brugarolas, J., Dozmorov, I., Levine, B., Wakeland, E.K., Lee-Kirsch, M.A., and Yan, N. (2013). Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes. Nat Immunol 14, 61–71.

Horan, K.A., Hansen, K., Jakobsen, M.R., Holm, C.K., Søby, S., Unterholzner, L., Thompson, M., West, J.A., Iversen, M.B., Rasmussen, S.B., et al. (2013). Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors. J Immunol.

Malfavon-Borja, R., Wu, L.I., Emerman, M., and Malik, H.S. (2013). Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes. Proc Natl Acad Sci USA.

Rowe, H.M., Kapopoulou, A., Corsinotti, A., Fasching, L., Macfarlan, T.S., Tarabay, Y., Viville, S., Jakobsson, J., Pfaff, S.L., and Trono, D. (2013). TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells. Genome Res. 23, 452–461.

Sun, L., Wu, J., Du, F., Chen, X., and Chen, Z.J. (2013). Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339, 786–791.

Wu, J., Sun, L., Chen, X., Du, F., Shi, H., Chen, C., and Chen, Z.J. (2013). Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339, 826–830.