Yanzy的个人博客分享 http://blog.sciencenet.cn/u/Yanzy

博文

Molecular Plant∣复旦大学揭示全基因组复制对被子植物物种多...

已有 2245 次阅读 2018-1-8 13:29 |系统分类:论文交流|关键词:学者

2018年1月6日,Molecular Plant在线发表了题为“Wide-Spread Whole Genome Duplications Contribute to Genome Complexity and Species Diversity in Angiosperms”的文章。该文章由复旦大学马红教授和戚继教授共同完成。


通过对59个公共基因组/转录组和46个新测序的转录组进行比较基因组和系统发育分析,发现了许多新的WGDs。提出了不同被子植物谱系的WGDs的指数基因损失率模型。检测到的大多数WGD与具有较大物种丰富度的谱系相关,这表明WGD对物种扩散的作用。


摘要:

基因复制(GDs)为产生新功能提供了进化潜力,而多倍体化或全基因组复制(WGD)最初使染色体倍增,并导致成千上万的保留重复。许多物种丰富的真核生物谱系中常见的证据,强烈的支持WGDs,因此WGDs被认为是物种多样化的主要驱动力。我们对59个公共基因组/转录组进行了比较基因组和系统发育分析,并对被子植物的主要谱系进行了46个新的转录组检测,通过对数以万计的基因家族树进行调查来检测大规模的基因复制事件。这些分析证实了以前报道的大部分WGDs,并为许多谱系中新的WGD提供了有力证据。检测到的WGD支持进化过程中的指数基因丢失模型,其估计半衰期约为2160万年,并且与高度多样化的谱系出现和全球气候变化相关。本文采用的新的数据集和分析方法检测到了许多在被子植物进化过程中广泛传播的新型WGDs,揭示了基本功能在基本细胞代谢中的优先保留,为WGD在促进被子植物扩散和增强其适应环境变化方面的作用提供了线索。


Abstract:

Gene duplications (GDs) provide evolutionary potentials for generating novel functions, while polyploidization or whole genome duplication (WGD) doubles the chromosomes initially and results in hundreds to thousands of retained duplicates. WGDs are strongly supported by evidence commonly found in many species-rich lineages of eukaryotes, thus are considered as a major driving force in species diversification. We performed comparative genomic and phylogenomic analyses on 59 public genomes/transcriptomes and 46 newly sequenced transcriptomes covering major lineages of angiosperms, to detect large-scale gene duplication events by survey of tens of thousands of gene family trees. These analyses confirmed most of the previously reported WGDs and provided strong evidence for novel ones in many lineages. The detected WGDs supported a model of exponential gene loss during evolution with an estimated half-life of approximately 21.6 million years, and were correlated with both the emergence of lineages with high degrees of diversification and periods of global climate changes. The new datasets and analyses here detected many novel WGDs widely spread during angiosperm evolution, uncovered preferential retention of gene functions in essential cellular metabolisms, and provided clues for the roles of WGD in promoting angiosperm radiation and enhancing their adaption to environmental changes.








https://m.sciencenet.cn/blog-634883-1093700.html

上一篇:Nature∣寄生植物菟丝子miRNA调节宿主植物靶mRNA的机制研究
下一篇:Plant Cell∣乔红研究组揭示组蛋白去乙酰化酶介导乙烯诱导的...

0

该博文允许注册用户评论 请点击登录 评论 (0 个评论)

数据加载中...
扫一扫,分享此博文

Archiver|手机版|科学网 ( 京ICP备07017567号-12 )

GMT+8, 2024-3-29 15:37

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社

返回顶部