Proc Natl Acad Sci U S A. 2013 Sep 16. A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis. abstract: In multicellular organisms, germ cells carry the hereditary material from one generation to the ne ...
给某校招聘的老板发信找postdoc position,他研究方向和我比较match比较有意思(就不告诉你我是因为他长得帅才想申的⊙﹏⊙),可惜已经没有职位了,但那位老板人还是挺nice的不到一个小时就回了信: Hi, I recently filled a post-doctoral position and have no positions open currently. You ...
Cell minireview: Long Noncoding RNAs Usher In a New Era in the Biology of Enhancers summary: Enhancer-associated long noncoding RNAs act over long distances and across chromosomes to activate transcription at distal promoters. Here, we address the latest advances made toward understand ...
22 August, 2013 Volume 51, Issue 4 On the cover: A man is shown reflecting on how ribosomes are made. Ribosome biogenesis is an extremely complex process involving 200 trans -acting assembly factors in budding yeast. Knowledge on ribosome assembly factors was seriously lagging in humans ...
RNA结构好火啊,这一期cell好几篇相关的文章。 On the cover: A virus must achieve a number of functions in its life cycle, often using a compact genome with a limited number of encoded proteins. As a result, many viral proteins are multifunctional. In this issue, Bornholdt, et al. (pp. 7 ...
The germ-cell lineage ensures the continuity of life through the generation of male and female gametes, which unite to form a totipotent zygote.Wehave previously demonstrated that, by using cytokines, embryonic stem cells and induced pluripotent stem cells can be induced into epiblast-like cells ( ...