Genetic and Neural Mechanisms that Inhibit Drosophila from Mating with Other Species 3 July, 2013 Volume 154, Issue 1 On the cover: Developmental mechanisms generate interspecies hybrids that cannot propagate, as alluded to by the artist's depiction of the mythical Minotaur's labyri ...
Androgen deprivation therapy (ADT) is widely used in the treatment of metastatic, recurrent and locally advanced prostate cancer. However, ADT, which leads to castrate testosterone level, is associated with numerous side effects, such as sexual dysfunction, osteoporosis, obesity and cardiovascu ...
ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing Hélène Royo, Haydn Prosser, Yaroslava Ruzankina, et al Genes Dev. 2013 27: 1484-1494 Access the most recent version at doi:10.1101/gad.219477.113 Abstract In mammals, homologs that fail to ...
Commons: On the cover: In th is issue, Goke, et al. (844–855) study the genome-wide chromatin interactions of the kinase ERK2 in human embryonic stem cells (hESCs). The interactions are part of a larger network, visualized on the cover as the railway system of Singapore. E ...
最新Nat Rev Genet： the epigenetic states imposed by PIWI on targets may actually drive piRNA production itself. These findings start to couple small RNA biogenesis with small - RNA -mediated epigenetics. C.elegans-Effects of PIWI pathways on chromatin. ...
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