1. 祝贺夏云生同学，其论文 Ultrasound-assisted nanocasting fabrication and high catalytic activity of three-dimensionally ordered mesoporous chromia for the combustion of formaldehyde, acetone, and methanol 被 Applied Catalysis B: Environmental 杂志录用。 2. 祝贺夏云生同学，其论文 Three-dimensionally ordered and wormhole-like mesoporous iron oxide catalysts highly active for the oxidation of acetone and methanol 被 Journal of Hazardous Materials 杂志录用。 3. 祝贺孟雪同学，其论文 Surfactant-assisted hydrothermal fabrication and visible-light-driven photocatalytic degradation of methylene blue over multiple morphological BiVO 4 single-crystallites 被 Materials Chemistry and Physics 杂志录用。 4. 祝贺赵振璇同学，其论文 Surfactant-assisted solvo- or hydrothermal fabrication and characterization of high-surface-area porous calcium carbonate with multiple morphologies 被 Microporous and Mesoporous Materials 杂志录用。 5. 祝贺邓积光同学，其论文 Single-crystalline mesoporous CaO supported Cr-V b inary oxide s: Highly active catalysts for the oxidative dehydrogenation of isobutane 被 Catalysis Today 杂志录用。
王 应 宽 2010-02-27 Beijing , China 第一篇被 SCI 收录的合作署名文章发表 2009 年在明尼苏达大学做访问学者期间，参与了合作导师 Roger Ruan 领导团队的科研工作。其间，有幸与团队里的博士后 Wang Liang ( 汪靓 ) 等合作署名发表论文一篇（ Cultivation of Green Algae Chlorella sp . in Different Wastewaters from Municipal Wastewater Treatment Plant ， http://www.springerlink.com/content/b46086hr6261610x/ ） 。文章内容是海藻生物油制取项目中关于在城市污水处理厂用不同成分污水养殖绿藻的研究成果。论文发表在 Springer 旗下期刊 Applied Biochemistry and Biotechnology （应用生物化学与生物技术），属于化学和材料科学类期刊，系 SCI 收录源刊，目前影响因子 1.643 。虽然影响因子不高，但文章的价值和影响较大，主要源于该研究系目前世界关注的热点，老板在此领域又处于国际领先地位，而且研究成果的应用前景广阔。海藻被认为是新一代生物质能源新的希望，对优质藻种，其含油量高，生长繁殖速度快，可以在污水中养殖，不与粮争地，不与人争粮，而且其通过藻类的养殖可以有效去除污水中的氮磷等富营养物，既能生产能源，又具有环保生态效益，因而具有良好的前景。 说来惭愧，此文乃有本人署名的第一篇 SCI 收录文章。个人水平低、不长进，从事编辑出版工作为人作嫁是一方面，但主要还是因为学科门类和研究方向不同的缘故。本人从事的专业为农业机械化（本科和硕士研究生专业）和编辑出版学（博士研究生专业）。前者属于农业工程学科领域，该领域的研究成果一般难以发表在 SCI 收录的期刊， SCI 收录农业工程学科领域的期刊也比较少。农业工程学科领域被 SCI 收录的论文大多是借了与其他学科交叉的势。很多该领域的成果大都发表在被工程索引（ Engineering Index, Ei Compendex ）收录的期刊。本人此前发表的农业工程方面的文章多被 EI 收录。后来转了向，投入较多精力从事编辑出版、开放存取、网络学术传播等方面的研究，发表论文数十篇，但属于人文社科领域，与 SCI 相去更远了。当然，也因为发表的这些文章大都是中文的，如果将来在国外期刊发些这方面的英文文章，也可能被 SSCI 收录（《社会科学引文索引》（ Social Science Citation Index ，简称 SSCI ），也算与 SCI 的亲戚攀上点关系了！ 论文第一作者靓妹系出名门，在国内时就读于同济大学和上海交通大学，赴美留学在明尼苏达大学获得博士学位，然后从事博士后研究。她天资聪颖，勤学不辍，发表了不少高水平论文。最近得知她又去亚利桑那州立大学的一个非常有名的 Algae实验室 Laboratory for Algae Research and Biotechnology （ http://larb.asu.edu/ ） 高就了。靓妹的爱国心令人感动，一心想着在美国多方学习提高，待学成后回国效力。她说：美国虽好，但还是时常想家，相信游子总有回到母亲怀抱的一天的。衷心希望国内各方为海外游子回国创业营造良好环境，以不辜负他们的赤子爱国心！在明尼苏达大学访学期间，在我的怂恿下，靓妹也在科学网开了博客（ http://www.sciencenet.cn/u/eversci/ ）。欢迎大家关注和支持！ 论文中文摘要如下。论文的英文全文 PDF 附后，欢迎感兴趣的同行斧正。 城市污水处理厂不同成分废水中绿藻培养 汪 靓1，民 敏1，李叶丛1，陈 灵1，陈以峰1，刘玉环1，王应宽1，阮榕生*1,2 1 Center for Biorefining, and Department of Bioproducts and Biosystems Engineering, University of Minnesota, 1390 Eckles Avenue, St. Paul, MN55108, USA 2南昌大学生物质转化教育部工程研究中心，生命科学与食品工程学院，南昌 330047 收稿日期 : 2009-08-21 接受日期： 2009-11-09 在线发表日期： 2009-11-24 摘 要： 该研究旨在评价绿藻在当地城市污水处理厂工艺流程中 4 个不同位置取样的污水中的生长状况，以及绿藻的生长对污水中氮、磷、化学需氧量 COD 和金属离子的去除效果。 4 种废水样品为：初级沉淀前的废水 #1 ，初级沉淀后的废水 #2 ，活性污泥槽中的废水 #3 ，污泥离心渗滤液 #4 （污泥离心渗滤后产生的废水）。在 4 种废水 #1 、 #2 、 #3 、 #4 中，绿藻在指数阶段的平均生长速率分别为 0.412, 0.429, 0.343, 和 0.948day1 。绿藻对废水 #1 、 #2 、 #4 中铵态氮（ NH4N ）的去除率分别为 82.4%, 74.7%, 和 78.3% 。废水 #3 中的硝态氮去除较明显，对无机氮主要形态的 NO3N 的去除率达 62.5%, 是养藻所产生的 NO2N 的 6.3 倍。绿藻对废水 #1 、 #2 、 #4 中磷的去除率分别为 83.2%, 90.6%, 和 85.6% ，对 COD 的去除率分别为 50.9%, 56.5%, 和 83.0% 。而 #3 废水中磷的去除率仅为 4.7% ， COD 的含量在绿藻生长后反而略有上升，可能是因为绿藻中小的有机分子光合作用产生排泄物所致。试验显示，离心渗滤液中的金属离子，特别是 Al, Ca, Fe, Mg 和 Mn 在绿藻养殖后被有效的去除了。研究结果表明，在营养富集的离心渗滤液中养殖海藻，为城市污水处理厂利用海藻养殖工艺循环利用渗滤液去除废水中的营养成分提供了新的途径，达到环保去污和生产有价值的生物燃油原料的双重目的。 关键词 ：城市污水，离心渗滤液，海藻，营养物去除，金属，绿藻 Cultivation of Green Algae Chlorella sp. in Different Wastewaters from Municipal Wastewater Treatment Plant LiangWang 1 , MinMin 1 , YecongLi 1 , PaulChen 1 , YifengChen 1 , YuhuanLiu 1 , YingkuanWang 1 and RogerRuan 1, 2 1 Center for Biorefining, and Department of Bioproducts and Biosystems Engineering, University of Minnesota, 1390 Eckles Avenue, St. Paul, MN55108, USA 2 Nanchang University, Nanchang, China Received: 21August2009 Accepted: 9November2009 Published online: 24November2009 Abstract: The objective of this study was to evaluate the growth of green algae Chlorella sp. on wastewaters sampled from four different points of the treatment process flow of a local municipal wastewater treatment plant (MWTP) and how well the algal growth removed nitrogen, phosphorus, chemical oxygen demand (COD), and metal ions from the wastewaters. The four wastewaters were wastewater before primary settling (#1 wastewater), wastewater after primary settling (#2 wastewater), wastewater after activated sludge tank (#3 wastewater), and centrate (#4 wastewater), which is the wastewater generated in sludge centrifuge. The average specific growth rates in the exponential period were 0.412, 0.429, 0.343, and 0.948day1 for wastewaters #1, #2, #3, and #4, respectively. The removal rates of NH4N were 82.4%, 74.7%, and 78.3% for wastewaters #1, #2, and #4, respectively. For #3 wastewater, 62.5% of NO3N, the major inorganic nitrogen form, was removed with 6.3-fold of NO2N generated. From wastewaters #1, #2, and #4, 83.2%, 90.6%, and 85.6% phosphorus and 50.9%, 56.5%, and 83.0% COD were removed, respectively. Only 4.7% was removed in #3 wastewater and the COD in #3 wastewater increased slightly after algal growth, probably due to the excretion of small photosynthetic organic molecules by algae. Metal ions, especially Al, Ca, Fe, Mg, and Mn in centrate, were found to be removed very efficiently. The results of this study suggest that growing algae in nutrient-rich centrate offers a new option of applying algal process in MWTP to manage the nutrient load for the aeration tank to which the centrate is returned, serving the dual roles of nutrient reduction and valuable biofuel feedstock production. Keywords ：Municipal wastewater，Centrate，Algae，Nutrients removal，Metal，Chlorella 附注： Applied Biochemistry and Biotechnology 期刊简介 Part A: Enzyme Engineering and Biotechnology Editor-in-Chief: Ashok Mulchandani ISSN: 0273-2289 (print version) ISSN: 1559-0291 (electronic version) Journal no. 12010 Humana Press 期刊 Applied Biochemistry and Biotechnology 出版社 Humana Press Inc. ISSN 0273-2289 (Print) 1599-0291 (Online) DOI 10.1007/s12010-009-8866-7 学科分类 化学和材料科学 SpringerLink Date 2009 年 11 月 24 日 This journal is devoted to publishing the highest quality innovative papers in the fields of biochemistry and biotechnology. The typical focus of the journal is to report applications of novel scientific and technological breakthroughs, as well as technological subjects that are still in the proof-of-concept stage. Applied Biochemistry and Biotechnology provides a forum for case studies and practical concepts of biotechnology, utilization, including controls, statistical data analysis, problem descriptions unique to a particular application, and bioprocess economic analyses. The journal publishes reviews deemed of interest to readers, as well as book reviews, meeting and symposia notices, and news items relating to biotechnology in both the industrial and academic communities. In addition, Applied Biochemistry and Biotechnology often publishes lists of patents and publications of special interest to readers. Related subjects Biochemistry Biophysics - Biotechnology Impact Factor: 1.643 * Journal Citation Reports, Thomson Reuters Abstracted/Indexed in: abstracted_indexed Abstracts in Anthropology, Academic OneFile, AGRICOLA, ASFA, Biochemistry and Biophysics Citation Index, Biological Abstracts, BIOSIS Previews, Biotechnology Citation Index, CAB Abstracts, CAB International, CEABA-VtB, Chemical Abstracts Service (CAS), ChemWeb, Compendex, CSA/Proquest, Current Abstracts, Current Awareness in Biological Sciences (CABS), Current Contents/ Agriculture, Biology Environmental Sciences, Current Contents/Life Sciences, DECHEMA, Elsevier Biobase, EMBASE, Food Science and Technology Abstracts, Gale, GeoRef, Global Health, Google Scholar, Health Reference Center Academic, IBIDS, INIS Atomindex, Journal Citation Reports/Science Edition, OCLC, PubMed/Medline, Reaction Citation Index, Science Citation Index, Science Citation Index Expanded (SciSearch), SCOPUS, Summon by Serial Solutions, TOC Premier 原文 Full-text PDF Cultivation of Green Algae Chlorella sp. in Differ
利用免疫调节来保护大脑 Nature med 阅读脾切除和最近德国关于免疫细胞保护大脑研究论文的感想. 去年看到过关于切除脾脏来保护大脑损伤的研究，感觉很有意思。 研究的思路是这样的，来自韩国的一个小组发现外周注射神经干细胞能保护脑出血后神经系统损伤。很自然，要能在脑内寻找这些外来的神经干细胞，结果很意外，发现脑内神经干细胞很少，不能解释其保护效应，但更奇怪的是，他们发现这些干细胞大部分达到脾脏。这个问题就来了，神经干细胞到脾脏能保护大脑吗？于是他们就把脾脏切除，结果发现，单纯切除脾脏就能保护大脑。 我回头找了一些文献，发现切除脾对保护中枢以外的器官已经有一些研究，例如保护肺损伤，其思路是这些器官损伤与炎症有关，而脾脏是促进炎症反应的，那么切脾脏保护这些炎症损伤的器官就理所当然了。 继续看，结果发现有人利用CdCL3来封闭巨噬细胞也能代替脾脏切除发挥对这些器官的保护作用，就是说巨噬细胞是其中比较重要的炎症细胞。 按理说，这些思路有意思，但也没什么大不了的。 最近德国学者在自然医学报道的另一个文章又让我对上述研究有些回忆，见 特殊细胞可在中风后保护大脑 , 英文全文 ,并感觉对自己非常失望。 德国学者的研究是，发现来自胸腺的Treg细胞是神经保护细胞。这个研究的本质是，这类细胞是抑制免疫或者炎症反应的重要细胞，能在中枢系统损伤的时候进入大脑，通过抑制免疫反应达到保护神经系统的作用。 这个工作应该与脾脏切除的研究属于一个整体，就是说：炎症反应在中枢神经系统损伤中非常重要，而炎症反应肯定要受到免疫系统的调节，调节炎症肯定存在两个不同的内容，一种是促进炎症发生的细胞或系统，另一种是抑制炎症反应的细胞或者系统。那么通过对这两种不同方向的免疫反应进行调节，就可以实现控制炎症，保护损伤的目的。这样的一个分析应该早就能想到，可惜我没有。现在感觉很遗憾。不过我想，将来可以用同样的思路对其他各类损伤开展深入研究。随着对Treg细胞的认识，例如找到如何调节的方法或药物，就可以用来治疗这些炎症了。另外对中枢神经系统来讲，因为血脑屏障的存在，一直是药物治疗的一个很大障碍，那么这些炎症调节细胞都能通过。也就是说可以作为药物的载体进行治疗神经损伤，不仅他们自己能治疗疾病，而且能带一些药物进入脑内，可以作为一种研究的思路。 另外一个值得大家注意的是，Preconditioning在各类器官保护中的研究，至今没有与免疫进行紧密联系，实际上免疫耐受与缺血耐受甚至其他各种耐受现象肯定存在重要联系。初步检索，没有发现任何有关报道。如果把 Precon与treg细胞结合起来，将是一个非常有意思的研究课题。 Brain. 2008 Mar;131(Pt 3):616-29. Epub 2007 Dec 20. Links Comment in: Brain. 2008 Aug;131(Pt 8):e100; author reply e101. Brain. 2008 Mar;131(Pt 3):604-5. Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke.Lee ST, Chu K , Jung KH, Kim SJ, Kim DH, Kang KM, Hong NH, Kim JH, Ban JJ, Park HK, Kim SU, Park CG, Lee SK, Kim M, Roh JK. Stroke Stem Cell Laboratory, Clinical Research Institute, Stem Cell Research Center, Department of Neurology, Seoul National University Hospital, Seoul, South Korea. Neural stem cell (NSC) transplantation has been investigated as a means to reconstitute the damaged brain after stroke. In this study, however, we investigated the effect on acute cerebral and peripheral inflammation after intracerebral haemorrhage (ICH). NSCs (H1 clone) from fetal human brain were injected intravenously (NSCs-iv, 5 million cells) or intracerebrally (NSCs-ic, 1 million cells) at 2 or 24 h after collagenase-induced ICH in a rat model. Only NSCs-iv-2 h resulted in fewer initial neurologic deteriorations and reduced brain oedema formation, inflammatory infiltrations (OX-42, myeloperoxidase) and apoptosis (activated caspase-3, TUNEL) compared to the vehicle-injected control animals. Rat neurosphere-iv-2 h, but not human fibroblast-iv-2 h, also reduced the brain oedema and the initial neurologic deficits. Human NSCs-iv-2 h also attenuated both cerebral and splenic activations of tumour necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and nuclear factor-kappa B (NF-kappa . However, we observed only a few stem cells in brain sections of the NSCs-iv-2 h group; in the main, they were detected in marginal zone of spleens. To investigate whether NSCs interact with spleen to reduce cerebral inflammation, we performed a splenectomy prior to ICH induction, which eliminated the effect of NSCs-iv-2 h transplantation on brain water content and inflammatory infiltrations. NSCs also inhibited in vitro macrophage activations after lipopolysaccharide stimulation in a cell-to-cell contact dependent manner. In summary, early intravenous NSC injection displayed anti-inflammatory functionality that promoted neuroprotection, mainly by interrupting splenic inflammatory responses after ICH. 这个研究发现外周注射干细胞是通过与脾脏相互作用 , 通过抑制全身免疫反应 , 发挥治疗脑出血损伤的 . 不知道是否在其他器官损伤也存在类似的情况吗 ? 例如肾脏和肝脏 . 这值得深入研究和思考 .: J Neurosci Res. 2008 Aug 1;86(10):2227-34. Links The spleen contributes to stroke-induced neurodegeneration.Ajmo CT Jr, Vernon DO, Collier L, Hall AA, Garbuzova-Davis S, Willing A, Pennypacker KR. Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida 33216, USA. Stroke, a cerebrovascular injury, is the leading cause of disability and third leading cause of death in the world. Recent reports indicate that inhibiting the inflammatory response to stroke enhances neurosurvival and limits expansion of the infarction. The immune response that is initiated in the spleen has been linked to the systemic inflammatory response to stroke, contributing to neurodegeneration. Here we show that removal of the spleen significantly reduces neurodegeneration after ischemic insult. Rats splenectomized 2 weeks before permanent middle cerebral artery occlusion had a 80% decrease in infarction volume in the brain compared with those rats that were subjected to the stroke surgery alone. Splenectomy also resulted in decreased numbers of activated microglia, macrophages, and neutrophils present in the brain tissue. Our results demonstrate that the peripheral immune response as mediated by the spleen is a major contributor to the inflammation that enhances neurodegeneration after stroke. 相关文献: pdf T reg cells prevent delayed lesion expansion in an IL-10dependent manner. They also temper the proinflammatory cytokine burst starting early time points after ischemia. Injection of IL-10 in the brain reduces infarct volume. TNF- , tumor necrosis factor- ; IFN- , interferon- . Katie Vicari 文章附件资料
标签: SCI论文
