博主:受 周公朴的博 文启发,刚才做了知识发现的分析,供大家研究参考。 喝咖啡与颈椎病 周公朴的博客 http://www.sciencenet.cn/m/user_content.aspx?id=392236#t1 我的怀疑是:喝咖啡可能会引起颈椎疾病 我以前不喝咖啡,大约5-6年前,第一次喝咖啡时,觉得颈项后面两侧有分别有两股流上冲,至头顶后侧的两边,人不是变精神了,而是发困,有一种被麻醉的感觉。以后再喝咖啡的时候,脖子后面有流(也许是神经电流?)上冲的情况,慢慢就弱化了,现在基本没有了。这个不细说了。 关键是,喝了几次,感觉到脖子转动颈椎骨头就开始嘎嘎作响。一直到现在,不喝咖啡就好些,喝了咖啡转脖子的响声就大些,骨头之间的阻力也大些。怀疑喝咖啡会引起钙的流失。呵呵。也许是疑心病。 本周开始决定不喝咖啡了,等一段时间,再看结果。 如果有人有同样的感受,或者你正在做这项研究。希望我的陈述对你有帮助。 http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi Start A-Literature C-Literature B-list Filter Literature A-query: cervical spondylosis C-query: Coffee The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 0 articles appeared in both literatures. The results of this search are saved under id # 4234 and can be accessed from the start page after you leave this session. There are 242 terms on the current B-list (27 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms. Rank Prob B-term 10.97bone mineral density 20.93moyamoya disease 30.90twin 40.83vitamin d receptor 50.83diabetes 60.79mri 70.78ct 80.73parkinson disease 90.73bone mineral content 100.72carpal tunnel syndrome 110.72hip 120.70e genotype 130.69meta 140.68diabetes mellitus 150.63axis 160.62neurofibromatosis 170.59bph 180.58apolipoprotein e 190.56pain 200.55cleft 210.48estrogen receptor 220.47nail 230.46osteo 240.45gtp binding protein 250.45cord 260.40kk 270.35proteoglycan 280.33candidate gene 290.33mass 300.33cholesterol 310.33men 320.33hole 330.30segment 340.29femur 350.25gas 360.25pth 370.24obesity 380.22amyotrophic lateral sclerosis 390.22sand 400.21ige 410.21weight 420.20rod 430.19blind 440.19hiv 450.18locomotor activity 460.17allele 470.16aaa 480.15fat 490.14fusion 500.13cyst 510.12lip 520.11sars 530.11hypertension 540.11nmr 550.10ant 560.10bar 570.09male 580.09phospholipase 590.08rf 600.08pilot 610.07leg 620.07low 630.07tumor necrosis factor 640.07ex 650.07aldolase 660.07spin 670.07dystonia 680.07image 690.06alopecia 700.06receptor gene 710.06multiple sclerosis 720.06total 730.05fast 740.05flip 750.05vitamin e 760.05arm 770.04coal 780.04limb 790.04term 800.04air 810.04benign 820.04impact 830.04superoxide dismutase 840.04year 850.03pseudo 860.03li 870.03tube 880.03or 890.03wave 900.03slip 910.03hand 920.02gene 930.02breast cancer 940.02fear 950.02glass 960.02sex 970.02cox 980.02al 990.02parathyroid hormone 1000.02variant 1010.02cold 1020.02ten 1030.02spa 1040.02cape 1050.02nine 1060.02gt 1070.01section 1080.01signal 1090.01death 1100.01double 1110.01kit 1120.01skip 1130.01scar 1140.01gel 1150.01dog 1160.01white 1170.01line 1180.01minor 1190.01ligand 1200.01domain 1210.01clamp 1220.01skin 1230.01family 1240.01stop 1250.01grass 1260.01unknown 1270.01novel 1280.01shear 1290.00body weight 1300.00region 1310.00brown 1320.00cat 1330.00mice 1340.003d 1350.00old 1360.00great 1370.00ca 1380.00node 1390.00trap 1400.00pygmy 1410.00eye 1420.00re 1430.00area 1440.00pre 1450.00phase 1460.00steel 1470.00tip 1480.00doc 1490.00pig 1500.00cod 1510.00protein 1520.00rotating 1530.00modification 1540.00vein 1550.00bag 1560.00ni 1570.00care 1580.00iv 1590.00receptor 1600.00past 1610.00large 1620.00alpha 1630.00ectopic 1640.00flat 1650.00beta 1660.00man 1670.00non 1680.00ray 1690.00fiber 1700.00group 1710.00ear 1720.00os 1730.00c3 1740.00map 1750.00contact 1760.00time 1770.00wind 1780.00block 1790.00cr 1800.00early 1810.00oh 1820.00nervous 1830.00sense 1840.00phosphate 1850.00mark 1860.00kinase 1870.00cell 1880.00base 1890.00slow 1900.00not 1910.00camp 1920.00angel 1930.00bank 1940.00safe 1950.00mid 1960.00red 1970.00membrane 1980.00a2 1990.00task 2000.00activity 2010.00amp 2020.00co 2030.00xi 2040.00fragment 2050.00damage 2060.00enhancement 2070.00bad 2080.00l a 2090.00spatial 2100.00reductase 2110.00sea 2120.00bi 2130.00end 2140.00neuro 2150.00vs 2160.00dry 2170.00key 2180.00spring 2190.00thin 2200.00point 2210.00tran 2220.00mode 2230.00band 2240.00fact 2250.00blue 2260.00march 2270.00hint 2280.00enigma 2290.00far 2300.00simple 2310.00little 2320.00genesis 2330.00ring 2340.00fate 2350.00secretion 2360.00best 2370.00set 2380.00gamma 2390.00aid 2400.00side 2410.00inhibitor 2420.00abnormal Restrict by semantic categories? 咖啡与颈椎病 相关基因与生物学研究的知识发现(知识点),对科研选题和研究有重要参考价值。 http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/view_b_txt.cgi?ID=4234 job id # 4234 started Fri Dec 10 04:00:52 2010 Max_citations: 50000 Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed Ngram_max: 3 4234 Search ARROWSMITH A A_query_raw: cervical spondylosis Fri Dec 10 04:01:16 2010 A query = cervical spondylosis started Fri Dec 10 04:01:16 2010 A query resulted in 5754 titles 4234 Search ARROWSMITH C C_query_raw: Coffee Fri Dec 10 04:01:55 2010 C: Coffee 7920 A: pubmed_query_A 5754 AC: ( cervical spondylosis ) AND ( Coffee ) 0 C query = Coffee started Fri Dec 10 04:01:55 2010 C query resulted in 7920 titles A AND C query resulted in 0 titles 3247 B-terms ready on Fri Dec 10 04:02:54 2010 Sem_filter: Genes Molecular Sequences, and Gene Protein Names 242 B-terms left after filter executed Fri Dec 10 04:04:31 2010 B-list on Fri Dec 10 04:06:06 2010 1 bone mineral density 2 moyamoya disease 3 twin 4 vitamin d receptor 5 diabetes 6 mri 7 ct 8 parkinson disease 9 bone mineral content 10 carpal tunnel syndrome 11 hip 12 e genotype 13 meta 14 diabetes mellitus 15 axis 16 neurofibromatosis 17 bph 18 apolipoprotein e 19 pain 20 cleft 21 estrogen receptor 22 nail 23 osteo 24 gtp binding protein 25 cord 26 kk 27 proteoglycan 咖啡与骨矿物质密度的关系;颈椎病与骨矿物质密度的关系的研究课题。 http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/show_sentences.cgi Start A-Literature C-Literature B-list Filter Literature AB literature B-term BC literature cervical spondylosis 颈椎病 bone mineral density 骨矿物质密度 Coffee 咖啡 1: High bone mineral density in pycnodysostotic patients with a novel mutation in the propeptide of cathepsin K.2007 Add to clipboard 2: Intra-individual variation in lumbar bone mineral density as a measure of spondylotic deformity in the elderly.2003 Add to clipboard 3: Inverse relation between osteoporosis and spondylosis in postmenopausal women as evaluated by bone mineral density and semiquantitative scoring of spinal degeneration.2003 Add to clipboard 4: 1999 Add to clipboard 5: Degenerative lumbar listhesis and bone mineral density in elderly women. The study of osteoporotic fractures.1999 Add to clipboard 6: Correlation between bone mineral density and intervertebral disc degeneration.1998 Add to clipboard 1: Coffee consumption and CYP1A2 genotype in relation to bone mineral density of the proximal femur in elderly men and women: a cohort study.2010 Add to clipboard 2: Bone mineral density and perceived menopausal symptoms: factors influencing low back pain in postmenopausal women.2009 Add to clipboard 3: Coffee consumption and bone mineral density in dialysis patients.2008 Add to clipboard 4: Diet and lifestyle associated with increased bone mineral density : cross-sectional study of Japanese elderly women at an osteoporosis outpatient clinic.2007 Add to clipboard 5: Habitual tea drinking and bone mineral density in postmenopausal Turkish women: investigation of prevalence of postmenopausal osteoporosis in Turkey (IPPOT Study).2007 Add to clipboard 6: Effects of coffee consumption and smoking habit on bone mineral density .2006 Add to clipboard 7: Evaluation of methods for prediction of bone mineral density by clinical and biochemical variables in perimenopausal women.2001 Add to clipboard 8: Tea drinking and bone mineral density in older women.2000 Add to clipboard 9: Is caffeine associated with bone mineral density in young adult women?2000 Add to clipboard 10: 2000 Add to clipboard 11: Bone mineral density and aortic calcification: the Study of Osteoporotic Fractures.1997 Add to clipboard 12: 1996 Add to clipboard