http://www.sciencedirect.com/science?_ob=ArticleURL_udi=B6T1B-4YYD7BT-2_user=9230734_coverDate=05%2F14%2F2010_rdoc=1_fmt=high_orig=search_origin=search_sort=d_docanchor=view=c_acct=C000059499_version=1_urlVersion=0_userid=9230734md5=f3c7d17c1c912957a6ae216db4153b1csearchtype=a Volume 375, Issue 9726 , 8 May 2010-14 May 2010, Pages 1624-1633 doi:10.1016/S0140-6736(10)60551-X | How to Cite or Link Using DOI Copyright 2010 Elsevier Ltd All rights reserved. Cited By in Scopus (6) Permissions Reprints Fast track Articles Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer : a multicentre randomised controlled trial Prof Wendy S Atkin PhD a , , , Rob Edwards PhD b , Ines Kralj-Hans PhD a , Kate Wooldrage MSc a , Andrew R Hart MD c , Prof John MA Northover MS d , D Max Parkin MD e , Prof Jane Wardle PhD f , Prof Stephen W Duffy MSc b , Prof Jack Cuzick PhD b and UK Flexible Sigmoidoscopy Trial Investigators a Department of Surgery and Cancer, Imperial College London, London, UK b Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK c School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK d Department of Surgery, St Mark's Hospital, Harrow, Middlesex, UK e Clinical Trials Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK f Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, London, UK Available online 27 April 2010. Refersto: Can endoscopy protect against colorectal cancer? An RCT The Lancet , Volume 375, Issue 9726 , 8 May 2010-14 May 2010 , Pages 1582-1584 , David F Ransohoff PDF (197 K) | Referredtoby: Can endoscopy protect against colorectal cancer? An RCT The Lancet , Volume 375, Issue 9726 , 8 May 2010-14 May 2010 , Pages 1582-1584 , David F Ransohoff PDF (197 K) | http://www.gopubmed.org/web/gopubmed/1?WEB1mOWEB10O00d000j10020001000h00100090000 flexible sigmoidoscopy and screening and prevention and colorectal cancer 315 documents semantically analyzed 1 2 Top Years Publications 2002 23 2005 21 2003 20 1999 19 2000 19 2001 19 1998 17 2004 16 1996 16 2007 13 2006 13 2008 12 1997 12 2009 11 1995 10 1992 10 1993 9 2010 8 1987 8 1994 7 1 2 1 2 Top Countries Publications USA 163 United Kingdom 31 Norway 17 Italy 9 Israel 8 Australia 7 Canada 6 Japan 4 Switzerland 3 Germany 3 Sweden 3 Hong Kong 2 Spain 2 Greece 2 China 2 Denmark 2 Singapore 1 Iran 1 New Zealand 1 Belgium 1 1 2 1 2 3 ... 7 Top Cities Publications London 14 Boston 11 Bethesda 10 Philadelphia 10 Minneapolis 9 Oslo 8 Pittsburgh 6 New York City 6 Atlanta 6 Washington, USA 6 Tel Aviv-Yafo 4 Ann Arbor 4 Houston 4 Cleveland 4 Indianapolis 3 Portland, USA 3 Los Angeles 3 Seattle 3 Oakland 3 Porsgrunn 3 1 2 3 ... 7 1 2 3 ... 7 Top Journals Publications Gut 12 Am J Gastroenterol 12 Gastroenterology 11 Prev Med 10 J Med Screen 9 Cancer 9 Am Fam Physician 8 Scand J Gastroenterol 7 Postgrad Med 7 Endoscopy 6 Ann Intern Med 6 Clin Gastroenterol Hepatol 6 Am J Prev Med 6 Lancet 5 Cancer Epidemiol Biomarkers Prev 5 J Gen Intern Med 5 Med J Aust 5 Cancer Detect Prev 5 Gastrointest Endosc 5 J Fam Pract 5 1 2 3 ... 7 1 2 3 ... 51 Top Terms Publications Sigmoidoscopy 315 Humans 311 Colorectal Neoplasms 290 Mass Screening 252 Middle Aged 205 Occult Blood 179 Colonoscopy 167 Patients 164 Hematologic Tests 160 Aged 149 Mortality 105 Health Planning Guidelines 92 Adenoma 87 Adult 83 Evaluation Studies as Topic 81 Methods 75 Colonic Neoplasms 72 Physicians 67 Incidence 62 Sensitivity and Specificity 58 1 2 3 ... 51 1 2 3 ... 51 Top Authors Publications Hoff G 18 Grotmol T 12 Bretthauer M 12 Wardle J 10 Atkin W 10 Gondal G 8 Hofstad B 7 Thiis-Evensen E 7 Weissfeld J 6 Eide T 6 Levin T 6 Borum M 5 Nadel M 5 McCaffery K 5 Skovlund E 5 Bond J 5 Bresalier R 4 Schn R 4 Hayes R 4 Gohagan J 4 1 2 3 ... 51
文献分析结果 http://www.gopubmed.org/web/gopubmed/1?WEB01qc7z5ow6e238I2dI3pI00h001000j100200010 All colonoscopy and interval cancer Colorectal Neoplasms 635 of 20,903 documents semantically analyzed top author statistics 1 2 Top Years Publications 2009 64 2006 64 2008 63 2007 51 2005 50 2004 43 2010 42 2003 36 2001 27 2002 26 1995 26 2000 21 1999 21 1996 15 1998 13 1993 12 1997 11 1994 9 1992 7 1988 7 1 2 1 2 3 Top Countries Publications USA 312 United Kingdom 48 Japan 36 South Korea 24 Italy 21 Netherlands 20 Germany 19 France 19 Australia 18 Canada 16 Norway 10 Israel 9 Denmark 8 Taiwan 8 China 5 Sweden 5 Spain 4 Switzerland 4 Belgium 3 Hong Kong 3 1 2 3 1 2 3 ... 11 Top Cities Publications New York 22 Seoul 19 Boston 19 Indianapolis 18 Bethesda 17 Seattle 16 Chapel Hill 15 Minneapolis 12 Pittsburgh 12 Heidelberg 11 Los Angeles 11 Fukuoka 11 Cleveland 11 London 9 Rome 9 Toronto 9 Tucson 8 Portland 7 Ann Arbor 7 Oakland 7 1 2 3 ... 11 1 2 3 ... 10 Top Journals Publications Gastroenterology 43 Am J Gastroenterol 41 Cancer Epidem Biomar 35 Dis Colon Rectum 34 Clin Gastroenterol Hepatol 25 Gut 23 Am J Epidemiol 18 Cancer 17 J Natl Cancer I 14 New Engl J Med 14 Arch Intern Med 13 Gastrointest Endosc 12 Cancer Cause Control 12 J Clin Gastroenterol 10 J Natl Cancer Inst 9 Jama 9 Scand J Gastroentero 9 N Engl J Med 8 Endoscopy 8 Br J Surg 8 1 2 3 ... 10 1 2 3 ... 85 Top Terms Publications Humans 612 Colonoscopy 568 Colorectal Neoplasms 528 Middle Aged 491 Confidence Intervals 431 Aged 423 Patients 400 Adenoma 329 Adult 266 Odds Ratio 262 Risk Factors 228 Colonic Neoplasms 187 Evaluation Studies as Topic 181 Mass Screening 180 Sigmoidoscopy 170 Diagnosis 157 Incidence 156 Aged, 80 and over 156 Neoplasms 138 Colonic Polyps 128 1 2 3 ... 85 1 2 3 ... 160 Top Authors Publications Sandler R 19 Bond J 17 Haile R 16 Rex D 14 Neugut A 13 Weissfeld J 12 Schatzkin A 10 Waye J 10 Potter J 10 Newcomb P 10 Schn R 10 Bostick R 10 Lieberman D 9 Baron J 9 Giovannucci E 9 Levin T 8 Church T 8 Forde K 8 Lee E 8 Frankl H 8 1 2 3 ... 160 最新研究进展 N Engl J Med. 2010 May 13;362(19):1795-803. Quality indicators for colonoscopy and the risk of interval cancer. Kaminski MF , Regula J , Kraszewska E , Polkowski M , Wojciechowska U , Didkowska J , Zwierko M , Rupinski M , Nowacki MP , Butruk E . Department of Gastroenterology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland. Abstract BACKGROUND: Although rates of detection of adenomatous lesions (tumors or polyps) and cecal intubation are recommended for use as quality indicators for screening colonoscopy, these measurements have not been validated, and their importance remains uncertain. METHODS: We used a multivariate Cox proportional-hazards regression model to evaluate the influence of quality indicators for colonoscopy on the risk of interval cancer. Data were collected from 186 endoscopists who were involved in a colonoscopy-based colorectal-cancer screening program involving 45,026 subjects. Interval cancer was defined as colorectal adenocarcinoma that was diagnosed between the time of screening colonoscopy and the scheduled time of surveillance colonoscopy. We derived data on quality indicators for colonoscopy from the screening program's database and data on interval cancers from cancer registries. The primary aim of the study was to assess the association between quality indicators for colonoscopy and the risk of interval cancer. RESULTS: A total of 42 interval colorectal cancers were identified during a period of 188,788 person-years. The endoscopist's rate of detection of adenomas was significantly associated with the risk of interval colorectal cancer (P=0.008), whereas the rate of cecal intubation was not significantly associated with this risk (P=0.50). The hazard ratios for adenoma detection rates of less than 11.0%, 11.0 to 14.9%, and 15.0 to 19.9%, as compared with a rate of 20.0% or higher, were 10.94 (95% confidence interval , 1.37 to 87.01), 10.75 (95% CI, 1.36 to 85.06), and 12.50 (95% CI, 1.51 to 103.43), respectively (P=0.02 for all comparisons). CONCLUSIONS: The adenoma detection rate is an independent predictor of the risk of interval colorectal cancer after screening colonoscopy. 2010 Massachusetts Medical Society PMID: 20463339 Publication Types, MeSH Terms Publication Types: Research Support, Non-U.S. Gov't MeSH Terms: Adenoma/diagnosis* Adult Aged Clinical Competence* Colonic Polyps/diagnosis* Colonoscopy/standards* Colorectal Neoplasms/diagnosis* Early Detection of Cancer/standards Humans Middle Aged Multivariate Analysis Poland Proportional Hazards Models Quality Indicators, Health Care* Risk Factors LinkOut - more resources Full Text Sources: HighWire Press Ovid Technologies, Inc. Swets Information Services Medical: Benign Tumors - MedlinePlus Health Information Colonic Polyps - MedlinePlus Health Information Colonoscopy - MedlinePlus Health Information Colorectal Cancer - MedlinePlus Health Information Endoscopy - MedlinePlus Health Information 相关文献 Related citations Variation in polyp detection rates at screening colonoscopy. Gastrointest Endosc. 2009 Jun; 69(7):1288-95. Variations between endoscopists in rates of detection of colorectal neoplasia and their impact on a regional screening program based on colonoscopy after fecal occult blood testing. Gastrointest Endosc. 2010 Feb; 71(2):335-41. Epub 2009 Nov 17. Five-year risk of colorectal neoplasia after negative screening colonoscopy. N Engl J Med. 2008 Sep 18; 359(12):1218-24. Review Dtsch Med Wochenschr. 2008 Nov; 133(47):2458-62. Epub 2008 Nov 12. Review Colonoscopy: a review of its yield for cancers and adenomas by indication. Am J Gastroenterol. 1995 Mar; 90(3):353-65. See reviews... | See all...
http://www.gopubmed.org/web/gopubmed/ 3,432 documents semantically analyzed top author statistics 1 2 Top Years Publications 2008 449 2009 420 2007 315 2006 312 2005 309 2003 250 2004 218 2002 165 2001 129 2010 113 2000 111 1999 83 1998 76 1997 66 1996 59 1994 48 1993 42 1991 42 1995 41 1990 35 1 2 1 2 3 4 5 Top Countries Publications USA 1,019 Japan 208 Germany 174 United Kingdom 161 Italy 160 France 138 Turkey 119 Canada 110 Spain 109 Australia 77 Netherlands 64 China 55 Brazil 53 Taiwan 52 Poland 47 Sweden 39 Switzerland 37 India 36 Belgium 33 Austria 32 1 2 3 4 5 1 2 3 ... 35 Top Cities Publications New York 74 Boston 72 Ankara 59 London 53 Paris 53 Baltimore 46 Tokyo 36 Madrid 36 Toronto 27 Minneapolis 27 Chicago 26 So Paulo 25 Los Angeles 25 Rochester, MN, USA 24 Okinawa 24 Bethesda 24 Taipei 23 Barcelona 23 Seoul 23 Osaka 23 1 2 3 ... 35 1 2 3 ... 41 Top Journals Publications Am J Kidney Dis 206 Nephrol Dial Transpl 153 Kidney Int 125 J Am Soc Nephrol 118 Nephrol Dial Transplant 64 Clin J Am Soc Nephrol 64 Transplant P 63 J Nephrol 56 Clin Nephrol 53 Pediatr Nephrol 53 Renal Failure 49 Transplantation 44 Kidney Int Suppl 39 Semin Dialysis 38 Am J Nephrol 37 Semin Nephrol 36 Nefrologia 35 Adv Chronic Kidney Dis 34 Nephron Clin Pract 32 Ren Fail 31 1 2 3 ... 41 1 2 3 ... 295 Top Terms Publications Humans 3,318 Risk Factors 2,981 Patients 2,744 Kidney Failure, Chronic 2,568 Middle Aged 1,736 Kidney 1,692 Adult 1,499 Aged 1,321 Kidney Diseases 1,263 Chronic Disease 1,199 Dialysis 1,041 Renal Dialysis 1,032 Diagnosis 947 Kidney Failure 932 Hypertension 866 Mortality 831 Prevalence 797 Evaluation Studies as Topic 796 Serum 762 Incidence 717 1 2 3 ... 295 1 2 3 ... 720 Top Authors Publications Zoccali C 26 Iseki K 25 Mallamaci F 21 Levey A 20 Tripepi G 20 McCullough P 19 Covic A 18 Haberal M 16 Ozdemir F 15 Chertow G 15 Nishizawa Y 15 Levin A 15 Abbott K 15 Coresh J 15 Agodoa L 15 Klag M 14 London G 14 Parfrey P 14 Gurin A 13 McClellan W 12 1 2 3 ... 720 最新研究报道 Adv Chronic Kidney Dis. 2010 May;17(3):237-45. Risk factors and screening for chronic kidney disease. Vassalotti JA , Fox CH , Becker BN . National Kidney Foundation Inc., New York, NY, USA. joseph.vassalotti@mssm.edu Abstract The asymptomatic nature of chronic kidney disease (CKD) makes explicit screening strategies for individuals at risk as the only means of early detection. This will allow more time for interventions to alter the natural history of the disease by delaying or preventing kidney disease progression and its complications. Patient awareness of CKD remains low. Utilization of CKD tests for patients at risk and interpretation of those tests to detect CKD by primary care physicians remain suboptimal. There is insufficient evidence to support general population screening. Diabetes, hypertension, and age 60 or greater are the primary CKD screening target conditions, based on assessments representative of the general populations in America and Norway. Although cardiovascular disease, family history of CKD, and ethnic and racial minorities are important predictors of CKD risk, they do not contribute significantly beyond the scope of diabetes, hypertension, and older age. Challenges remain to define the roles in the community of the primary physician and nephrologist to implement intensive blood pressure control, use of renin-angiotensin system blockers for proteinuric patients and nephrology referral as indicated. The electronic medical record holds the most promise in CKD screening through improvements in the flow of information and application of clinical decision support. Copyright 2010 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved. PMID: 20439092
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