http://www.gopubmed.org/web/gopubmed/1?WEB0yn7s8004ktz4IjI1I00f01000j100500001001100000011140030701200300 检索策略:cancer misdiagnosis Neoplasms 20,528 of 20,871 documents semantically analyzed Term: Neoplasms Description: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. Synonyms: Cancer, Tumor, Cancers, Tumors, Benign Neoplasm, Neoplasm, Benign Neoplasms 1 2 3 Top Years Publications 2008 984 2007 921 2004 893 2006 891 2005 885 2003 857 2002 796 2009 766 2000 713 2001 674 1998 622 1999 620 1997 609 1996 526 1995 508 1990 468 1986 453 1994 452 1993 448 1989 432 1 2 3 1 2 3 ... 6 Top Countries Publications USA 4,210 United Kingdom 1,003 Japan 857 Italy 741 Germany 738 France 455 Netherlands 440 China 364 Spain 352 Canada 344 Australia 282 South Korea 220 Turkey 205 India 174 Sweden 159 Belgium 156 Taiwan 155 Denmark 138 Austria 137 Israel 113 1 2 3 ... 6 1 2 3 ... 60 Top Cities Publications New York 329 Boston 242 London 240 Houston 185 Philadelphia 178 Chicago 175 Seoul 159 Tokyo 128 Amsterdam 128 Paris 120 Toronto 118 Baltimore 116 Pittsburgh 114 Rome 106 Washington 103 Bethesda 102 Seattle 100 Ann Arbor 100 San Francisco 97 Cleveland 92 1 2 3 ... 60 1 2 3 ... 117 Top Journals Publications Cancer 488 Radiology 457 Acta Cytol 450 Clin Nucl Med 314 Am J Roentgenol 306 Diagn Cytopathol 237 Am J Clin Pathol 227 Lancet 173 J Nucl Med 171 Arch Pathol Lab Med 162 Am J Surg Pathol 155 Rofo-fortschr Rontg 154 J Urology 154 Eur Radiol 135 Acad Radiol 133 Clin Radiol 129 Urology 122 Cytopathology 122 Int J Radiat Oncol 117 Jama-j Am Med Assoc 114 1 2 3 ... 117 1 2 3 ... 585 Top Terms Publications Humans 20,157 Patients 9,576 Middle Aged 8,630 Diagnosis 8,560 Diagnostic Errors 7,855 Adult 7,806 Aged 6,541 Neoplasms 6,424 False Positive Reactions 5,279 Evaluation Studies as Topic 5,214 False Negative Reactions 5,034 Diagnosis, Differential 4,294 Carcinoma 4,278 Biopsy 4,062 Breast Neoplasms 3,254 Sensitivity and Specificity 3,204 Observer Variation 2,997 Tomography, X-Ray Computed 2,314 Neoplasm Metastasis 2,226 Adolescent 2,119 1 2 3 ... 585 http://www.dailymail.co.uk/news/article-1238818/Miracle-baby-cancer-girl-Nieka-Chetwyn-left-infertile.html Miracle baby for cancer girl 'left infertile' By James Tozer Last updated at 12:56 AM on 28th December 2009 Comments ( 32 ) Add to My Stories She grew up longing to have a baby one day, but believing it would be impossible. Nieka Chetwyn was a child when she became a victim of one of Britain's worst cancer misdiagnosis scandals and was told the gruelling treatment had probably left her infertile. Today, however, 25-year-old Nieka and her family are celebrating what they say is a 'miracle' after she gave birth to a healthy boy. Son Joscar arrived two weeks early on December 17 weighing 7lb 14oz. Simply wonderful: Nieka Chetwyn with Joscar 'I'd always wanted to have children but I thought I'd have to adopt so this is simply wonderful,' Nieka, a paediatric nurse, said yesterday. In 1993, when she was eight, Nieka's plight was highlighted on the front page of the Daily Mail after she lost her hair to chemotherapy. She was given the aggressive treatment based on a consultant's incorrect diagnosis of her cancer and doctors had to break the news that she would almost certainly never have children. Thousands more patients' test results had to be rechecked and scores received compensation after doctors discovered they may have gone through the trauma of cancer treatment unnecessarily. Nieka's parents didn't receive a penny, however, as she had indeed been suffering from cancer, but of a different type to the one diagnosed. Enlarge Flashback: Nieka Chetwyn, from the Mail in 1993 The family were left wondering whether her future had been permanently blighted and if such aggressive treatment had actually been necessary. With the help of dedicated cancer specialists Nieka was eventually given the all-clear, but no one ever dared give her hope that she would be able to conceive naturally. 'I remember walking with her at a time when she had no hair because of the treatment,' said her mother, Kren. 'She said, But Mummy, I'd like to have a baby one day. It brought tears to my eyes. My husband told her, We'll do whatever it takes, we'll even sell the house and get you the best medical treatment. So for Nieka to have a child, and for us to have our first grandchild, it really is a miracle.' Nieka, of Prestwich, Greater Manchester, and her partner Sean O'Donovan, 27, were shocked to find she was pregnant not least because she was taking the Pill to regulate her hormones. 'I couldn't 100 per cent accept I was pregnant until I actually gave birth!' she said. She was seven when a suspicious lump was found in her calf. Doctors carried out a biopsy which was sent to Selly Oak Hospital in Birmingham for analysis by Dr Carol Starkie, who diagnosed a Ewing's sarcoma. After surgery Nieka had 18 gruelling sessions of chemotherapy at Royal Manchester Children's Hospital. In the meantime concern was being raised at Dr Starkie's performance and she retired on health grounds as more than 2,000 cases were rechecked. Tests revealed that Nieka had actually been suffering from a different type of cancer, called a rhabdomyosarcoma. But by now doctors had to persist with the original course of treatment. Her father, Philip, said: 'The awful thing is that we'll never know if a less arduous treatment would have done the trick.' Read more: http://www.dailymail.co.uk/news/article-1238818/Miracle-baby-cancer-girl-Nieka-Chetwyn-left-infertile.html#ixzz0b9isCIGp http://www.sciencenet.cn/htmlnews/2009/12/226646.shtm 英国患癌女子奇迹般产下男婴 曾被断定无法生育 据《每日邮报》12月28日报道,英国儿科护士妮卡-奇特温(NiekaChetwyn)8岁的时候因医生误诊接受癌症治疗,结果被断定永远失去生育能力。然而,两周前,妮卡却在医院产下一个健康的宝宝,一家人在狂喜中见证了奇迹的诞生。 妮卡今年25岁,是 英国最严重的一起癌症误诊丑闻的受害者, 当时她被告知,漫长的治疗可能已令其永远不能实现母亲梦。但是,经过不懈努力,妮卡终于在12月17日产下一名男婴,重7磅14盎司(约合3.57公斤),取名乔斯卡(Joscar)。妮卡27日在接受采访时说:我一直期待着拥有自己的孩子,可我想实现这一愿望只能靠收养了,所以说,这真的是个奇迹。 1993年,8岁的妮卡因化疗头发全掉光,《每日邮报》当时曾在头版报道了她的遭遇。由于误诊,她接受了积极的癌症治疗,结果身体遭受了严重伤害,医生当时称小妮卡几乎肯定失去生育能力。英国卫生当局还对数千患者的检查结果重新核对,发现很多患者可能因不必要的癌症治疗而遭遇创伤,这些人因此获得了补偿。 然而,妮卡的父母并未得到一分钱的补偿,因为她的确患有癌症,但这却是一种不同于被诊断类型的癌症。家人一直想搞清小妮卡是否会永远活在这起意外事故的阴影下,这种积极的治疗是否真的有必要。在多位癌症专家的帮助下,妮卡最终被确定不会有生命危险,但没人敢保证她将来有一天可以自然受孕。 妮卡7岁那年,父母在她的腿肚子上发现了一个可疑肿块。医生随后进行了活组织检查,并将检查结果送到伯明翰塞利-奥克医院供卡罗尔-斯塔基(Carol Starkie)博士分析,后者断定妮卡患上了尤文氏肉瘤。妮卡随后进行了手术,并在曼彻斯特皇家儿童医院接受了18个疗程的漫长化疗。 与此同时,有人对斯塔基的医术提出了质疑,英国卫生当局于是对2000多个斯塔基接手的病例进行了复检。复检结果表明, 妮卡的确患有癌症,但不是尤文氏肉瘤,而是横纹肌肉瘤。 尽管如此,由于贻误了治疗的最佳时机,主治医生不得不坚持原来的方案。妮卡的父亲菲利普说:糟糕的是,我们恐怕永远不清楚更为稳妥的治疗是否可以治愈妮卡所患的疾病。 更多阅读 《每日邮报》相关报道(英文)