2011年度罗伯特·科赫奖揭晓 奖励生物医学领域研究者 http://news.sciencenet.cn/htmlnews/2011/2/244167.shtm Robert Koch Awards 2011 for pioneer research in the fields of microbiology and molecular biology and for major contributions to a sustainable development of the German and European Science System http://www.robert-koch-stiftung.de/index.php?article_id=81clang=1 http://scholar.google.com.hk/scholar?hl=enq=Gal%C3%A1n+J++BacteriolbtnG=Searchas_sdt=0%2C5as_ylo=as_vis=0 Type III secretion machines: bacterial devices for protein delivery into host cells from ucsd.edu JE Galán … - Science, 1999 - sciencemag.org ... K. Eichelberg, C. Ginocchio, JE Galán , J . Bacteriol . 176, 4501 (1994) ; F. Fan and RM Macnab, J . Biol. Chem. 271, 31981 (1996) . ... Microbiol. 16, 291 (1995) ; K. Kaniga, D. Trollinger, JE Galán , J . Bacteriol . ... Cited by 822 - Related articles - BL Direct - All 11 versions Supramolecular structure of the Salmonella typhimurium type III protein secretion system …, J Uralil, M Lara-Tejero, A Sukhan, JE Galán … - Science, 1998 - sciencemag.org ... Downloaded from Page 5. FC Soncini, F. Solomon, EA Groisman, ibid., p. 7800. 4. C. Collazo and JE Galán , Mol. Microbiol. ... 6. Salmonella typhimurium strains were derivatives of SJW1103 from pnas.org JE Galán , R Curtiss - … of the National Academy of Sciences …, 1989 - National Acad Sciences ... (cell invasion/bacterial pathogenesis/bacterial adhesion/TnphoA) JORGE E. GALAN * AND RoY CURTISS III Department of Biology, Washington University, Saint Louis, MO 63130 Communicated by Emil C. Gotschlich, May 5, 1989 ... Page 2. 6384 Microbiology: Galan and Curtiss ... Cited by 504 - Related articles - All 8 versions S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells from psu.edu …, LM Chen, KE Schuebel, XR Bustelo, JE Galán - Cell, 1998 - Elsevier ... Responses in Host Cells. Wolf-Dietrich Hardt 1 , § , Li-Mei Chen 1 , Kornel E. Schuebel 2 , Xosé R. Bustelo 2 and Jorge E. Galán Corresponding Author Contact Information , E-mail The Corresponding Author , 1 , ‡. 1 Department of ... Cited by 481 - Related articles - BL Direct - All 19 versions Molecular characterization and assembly of the needle complex of the Salmonella typhimurium type III protein secretion system from pnas.org …, SI Aizawa, JE Galán - Proceedings of the …, 2000 - National Acad Sciences ... Eichelberg K,; Ginocchio C,; Galán JE. (1994) J Bacteriol 176:4501–4510, pmid:8045880. ↵: Collazo CM,; Zierler MK,; Galán JE. (1995) Mol Microbiol 15:25–38, pmid:7752894. ... Kaniga K,; Trollinger D,; Galán JE. (1995) J Bacteriol 177:7078–7085, pmid:8522512. ... Cited by 223 - Related articles - BL Direct - All 15 versions Protein delivery into eukaryotic cells by type III secretion machines from yale.edu JE Galán … - Nature, 2006 - nature.com ... PubMed | ISI | ChemPort |; Sukhan, A., Kubori, T., Wilson, J . Galán , JE Genetic analysis of assembly of the Salmonellaenterica serovar Typhimurium type III secretion-associated needle complex. J . Bacteriol . 183, 1159–1167 (2001) | Article | PubMed | ChemPort |; Kubori, T ... Cited by 313 - Related articles - BL Direct - All 12 versions Contact with epithelial cells induces the formation of surface appendages on Salmonella typhimurium …, SB Olmsted, CL Wells, JE Galán - Cell, 1994 - Elsevier ... Galan , JE, Ginocchio, C., and Costeas, P. (1992). Molecular and functional characterization of the Salmonella typhimurlum invasion gene invA: homology of InvA to members of a new protein family. J . Bacteriol . 17, 43384349. Galan , JE, Pace, J ., and Hayman, MJ (1992). ... Cited by 209 - Related articles - BL Direct - All 9 versions A secreted Salmonella protein with homology to an avirulence determinant of plant pathogenic bacteria from pnas.org …, JE Galán - … of the National Academy of Sciences …, 1997 - National Acad Sciences ... Kaniga K,; Tucker SC,; Trollinger D,; Galán JE. (1995) J Bacteriol 177:3965–3971, pmid:7608068. Abstract/FREE Full Text. ↵: Kaniga K,; Trollinger D,; Galán JE. (1995) J Bacteriol 177:7078–7085, pmid:8522512. Abstract/FREE ... Cited by 170 - Related articles - BL Direct - All 12 versions A substrate of the centisome 63 type III protein secretion system of Salmonella typhimurium is encoded by a cryptic bacteriophage from pnas.org WD Hardt, H Urlaub, JE Galán - Proceedings of the …, 1998 - National Acad Sciences ... Proc Natl Acad Sci USA 89:5976–5980, pmid:1631083. Abstract/FREE Full Text. ↵: Galán JE,; Ginocchio C,; Costeas P. (1992) J Bacteriol 17:4338–4349. ↵: Groisman EA,; Ochman H. (1993) EMBO J 12:3779–3787, pmid:8404849. ... Cited by 152 - Related articles - BL Direct - All 14 versions Striking a balance: modulation of the actin cytoskeleton by Salmonella from pnas.org JE Galán , D Zhou - … of the National Academy of Sciences …, 2000 - National Acad Sciences ... Kaniga K,; Trollinger D,; Galán JE. (1995) J Bacteriol 177:7078–7085, pmid:8522512. Abstract/FREE Full Text. ↵: Kaniga K,; Tucker SC,; Trollinger D,; Galán JE. (1995) J Bacteriol 177:3965–3971, pmid:7608068. Abstract/FREE ... Cited by 180 - Related articles - BL Direct - All 19 versions JE Galán , K Nakayama, R Curtiss - Gene, 1990 - Elsevier ... Vac cine 6 (1988a) 155160. Curtiss III, RK, Kelly, SM, Gulig, PA, GentryWeeks, CR and Galan , JE: Avirulent Salmonella expressing virulence antigens from other pathogens for use as orallyadministered vaccines. ... J . Bacteriol . 169 (1987) 43494354. ... Cited by 160 - Related articles - All 5 versions Salmonella spp. are cytotoxic for cultured macrophages …, K Kaniga, JE Galán - Molecular microbiology, 1996 - interscience.wiley.com ... Li Mei Chen, Koné Kaniga y and Jorge E. Galán * Department of Molecular Genetics and Microbiology, School of Medicine, State University of New York at Stony Brook, Stony Brook, New York 11794–5222, USA. Summary ... E-mail galan @as- terix.bio.sunysb.edu; Tel. ... Cited by 289 - Related articles - BL Direct - All 7 versions Chaperone release and unfolding of substrates in type III secretion from yale.edu …, JE Galán - Nature, 2005 - nature.com ... 1355 (2003) | Article | PubMed | ISI | ChemPort |; Akeda, Y. Galan , JE Genetic analysis of the Salmonella enterica type III secretion-associated ATPase InvC defines discrete functional domains. J . Bacteriol . 186, 2402−2412 (2004) | Article | PubMed | ISI | ChemPort |; Kaniga, K ... Cited by 137 - Related articles - BL Direct - All 13 versions The invasion‐associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cell …, JE Galán - Molecular microbiology, 1997 - Wiley Online Library ... J Bacteriol 177: 7078–7085. Kaniga, K., Tucker, SC, Trollinger, D., and Galán , JE (1995b) Homologues of the Shigella IpaB and IpaC inva- sins are required for Salmonella typhimurium entry into cultured epithelial cells. J Bacteriol 177: 3965–3971. ... Cited by 212 - Related articles - BL Direct - All 7 versions The invasion-associated type-III protein secretion system in Salmonella-a review1 from psu.edu …, JE Galán - Gene, 1997 - Elsevier ... Carmen M. Collazo and Jorge E. Galán *. ... For a recent discussion of other subjects related to the interactions of Salmonella with host cells, readers are referred to other reviews (Finlay, 1994; Galán , 1994 Galán , 1995). 2. General features of the type-III protein secretory systems. ... Cited by 126 - Related articles - All 10 versions Interaction of Salmonella with host cells through the centisome 63 type III secretion system from yale.edu JE Galán - Current opinion in microbiology, 1999 - Elsevier ... Infect Immun (1998) in press.. 9••. T Kubori, Y Matsushima, D Nakamura, J Uralil, M Lara-Tejero, A Sukhan, JE Galán and SI Aizawa, Supramolecular structure of the Salmonella typhimurium type III protein secretion system. Science 280 (1998), pp. ... Cited by 117 - Related articles - BL Direct - All 7 versions The Salmonella typhimurium tyrosine phosphatase SptP is translocated into host cells and disrupts the actin cytoskeleton Y Fu, JE Galán - Molecular microbiology, 1998 - Wiley Online Library ... PubMed. 20 Kaniga, K., Tucker, SC, Trollinger, D., Galán , JE (1995b) Homologues of the Shigella IpaB and IpaC invasins are required for Salmonella typhimurium entry into cultured epithelial cells. J Bacteriol 177: 3965–3971. PubMed. 21 Kaniga, K., Uralil, J ., Bliska, JB, Galán ... Cited by 171 - Related articles - BL Direct - All 7 versions Salmonella entry into host cells: the work in concert of type III secreted effector proteins …, J Galán - Microbes and Infection, 2001 - Elsevier ... All rights reserved. Cited By in Scopus (113). Permissions Reprints. Salmonella entry into host cells: the work in concert of type III secreted effector proteins. Daoguo Zhou Corresponding Author Contact Information , E-mail The Corresponding Author , a and Jorge Galán b. ... Cited by 154 - Related articles - All 5 versions Virulence and vaccine potential of phoP mutants of Salmonella typhimurium* 1 JE Galán , R Curtiss - Microbial pathogenesis, 1989 - Elsevier ... Vaccine 1988; 6: 15560. Curtiss Rill, Kelly SM, Gulig PA, GentryWeeks CR, Galan JE. ... 28. Kier LD, Weppelman R, Ames BN. Resolution and purification of two phosphatases and a cyclic phosphodiesterase of S. typhimurium. J Bacteriol 1977; 130: 4208. 29. ... Cited by 112 - Related articles - All 4 versions Delivery of epitopes by the Salmonella type III secretion system for vaccine development from psu.edu H Rüssmann, H Shams, F Poblete, Y Fu, JE Galán … - Science, 1998 - sciencemag.org ... K. Kaniga, D. Trollinger, J . E. Galán , J . Bacteriol . 177, 7078 (1995) . A. Deckhut, et al., J . Immunol. ... SptP 35-62 -IVNP 366-374 , which carries a mutation within the binding site of SicP, the SptP-specific chaperone Molecular and functional characterization of the Salmonella typhimurium invasion gene invA: homology of InvA to members of a new protein family JE Galán , C Ginocchio… - J . Bacteriol , 1992 Cited by 51 - Related articles Molecular genetic bases of Salmonella entry into host cells JE Galán - Molecular microbiology, 1996 - interscience.wiley.com ... Mutagenesis analysis has revealed that it is likely that no more invasion functions are encoded upstream of invH (G. Otto, K. Kaniga and J . Galan , unpublished). However, it is not known if additional invasion determinants are encoded downstream of orgA. ... 268 J . E. Galan ... Cited by 309 - Related articles - BL Direct - All 5 versions SALMONELLA INTERACTIONS WITH HOST CELLS from psu.edu JE Galán - Annu. Rev. Cell Dev. Biol, 2001 - Citeseer ... Type III Secretion at Work Jorge E. Galán Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06536; e-mail: jorge. galan @yale.edu ... 1993, Galán et al. 1992, Garcia-del Portillo Finlay 1994). ... Cited by 366 - Related articles - View as HTML - BL Direct - All 10 versions Cross-talk between bacterial pathogens and their host cells JE Galán , JB Bliska - Annual review of cell and developmental …, 1996 - annualreviews.org ... 12: 221-255 (Volume publication date November 1996). Jorge E. Galán and James B. Bliska. Department of Molecular Genetics and Microbiology, State University of New York at Stony Brook, Stony Brook, New York 11794-5222. ... Cited by 124 - Related articles - BL Direct - All 4 versions Salmonella type III secretion‐associated chaperones confer secretion‐pathway specificity from psu.edu …, JE Galán - Molecular microbiology, 2004 - Wiley Online Library ... Fu, Y., and Galán , JE (1998) Identification of a specific chaperone for SptP, a substrate of the centisome 63 type III secretion system of Salmonella typhimurium. J Bacteriol 180. Cited by 95 - Related articles - BL Direct - All 13 versions Temporal regulation of Salmonella virulence effector function by proteasome-dependent protein degradation from cell.com …, JE Galán - Cell, 2003 - Elsevier ... Temporal Regulation of Salmonella Virulence Effector Function by Proteasome-Dependent Protein Degradation. Tomoko Kubori a and Jorge E. Galán Corresponding Author Contact Information , a , E-mail The Corresponding Author. ... 2002) and (Stebbins and Galán 2001). ... Cited by 119 - Related articles - All 23 versions A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurlum …, J Uralil, JB Bliska, JE Galán - Molecular …, 1996 - interscience.wiley.com ... sine phosphatases. 0 f 996 Blackwell Science Ltd, Molecular Microbiology, 21, 633-641 Page 4. 636 K, Kaniga, J . Uralil, J . B. Bliska and J . E. Galan 1u. Human gastrin 1 - 17 * SptP ... Page 6. 638 K. Kaniga, J . Uralil, JB Bliska and J . E. Galan lglewski, 1984; Apodaca etal., 1995). ... Cited by 149 - Related articles - BL Direct - All 4 versions Unique features of a highly pathogenic Campylobacter jejuni strain from nih.gov …, C Perbost, T Jarvie, L Du, JE Galán - Infection and …, 2006 - Am Soc Microbiol ... Dirk Hofreuter, 1 Jennifer Tsai, 2 Robert O. Watson, 1 Veronica Novik, 1 Bill Altman, 2 Michelle Benitez, 2 Christina Clark, 2 Clotilde Perbost, 2 Thomas Jarvie, 2 Lei Du, 2 and Jorge E. Galán 1 * ... S6 in the supplemental material; J , see Fig. 2; K, see Fig. 6A). ... Cited by 101 - Related articles - BL Direct - All 14 versions Cloning and molecular characterization of a gene involved in Salmonella adherence and invasion of cultured epithelial cells …, I Rosenshine, BB Finlay, JE Galán - Molecular …, 1993 - interscience.wiley.com ... 1988). A number of phoA gene fusions in Salmonella yielding enzymatically active alkaline phosphatase have been shown to exhibit a non-specific toxic effect resulting in diminished levels of invasion { J , Galan , unpublished). In ... Cited by 94 - Related articles - BL Direct - All 5 versions