somewhere i have never travelled, gladly beyond any experience, 很多我未旅行过的地方，欣然存在于任何经验之外。 your eyes have their silence: 你的眼神多么寂静， in your most frail gesture are things which enclose me, 至柔的手势中有力量将我关闭。 or which i cannot touch because they are too near 我无法触及，因为它太靠近。 slightest look easily will unclose me 你轻轻的一瞥，便轻易地将我开启， though i have closed myself as fingers, 虽然我关闭自己，如握紧手指， you open always petal by petal myself as Spring opens (touching skilfully, mysteriously) her first rose 你总是一瓣一瓣地解开我，如春天一样神秘轻巧的碰触它开启的第一朵蔷薇。 or if your wish be to close me, 若是你要关闭我， i and my life will shut very beautifully, suddenly, 我和我的生命将合拢。很美丽地，很骤然地， as when the heart of this flower imagines the snow carefully everywhere descending... 正如这朵花的心脏，梦幻中雪花一般小心翼翼地四处落下。
美国《外交政策》杂志11月号发表了国务卿希拉里·克林顿的署名文章：《美国的太平洋世纪》。顾“题”思义，文章的核心思想是要向全世界、特别是亚太地区宣告，美国的战略中心已经东移；太平洋是“美国的天下”，美国要领导太平洋。下面是其具体内容： America’s Pacific Century 美国的太平洋世纪 Op-Ed by U.S. Secretary of State Hillary Rodham Clinton 美国国务卿希拉里·克林顿 The future of politics will be decided in Asia, not Afghanistan or Iraq, and the United States will be right at the center of the action. 未来的政治将决定于亚洲，而不是阿富汗或伊拉克。美国将置身于行动的中心。 As the war in Iraq winds down and America begins to withdraw its forces from Afghanistan, the United States stands at a pivot point. Over the last 10 years, we have allocated immense resources to those two theaters. In the next 10 years, we need to be smart and systematic about where we invest time and energy, so that we put ourselves in the best position to sustain our leadership, secure our interests, and advance our values. One of the most important tasks of American statecraft over the next decade will therefore be to lock in a substantially increased investment — diplomatic, economic, strategic, and otherwise — in the Asia-Pacific region. 随着伊拉克战争接近尾声以及美国开始从阿富汗撤军，美国现在处于一个转折点。在过去10年中，我们向上述两个战区投入了巨大的资源。在今后10年中，我们对在哪里投入时间和精力需要做到灵活并有系统性，从而让我们自己处于最有利的地位，以保持我们的领导作用，保障我们的利益，推进我们的价值观。因此，今后10年美国外交方略的最重要的使命之一将是把大幅增加的投入——在外交、经济、战略和其他方面——锁定于亚太地区。 The Asia-Pacific has become a key driver of global politics. Stretching from the Indian subcontinent to the western shores of the Americas, the region spans two oceans — the Pacific and the Indian — that are increasingly linked by shipping and strategy. It boasts almost half the world’s population. It includes many of the key engines of the global economy, as well as the largest emitters of greenhouse gases. It is home to several of our key allies and important emerging powers like China, India, and Indonesia. 亚太地区已成为全球政治的一个关键的驱动力。这个地区从印度次大陆一直延伸到美洲西海岸，横跨太平洋和印度洋两个大洋，由于交通运输和战略因素而日益紧密地联系在一起。亚太地区的人口几乎占到世界总人口的一半。这个地区拥有很多全球经济的重要引擎，也有最大的温室气体排放国。该地区有我们的一些重要盟国，还有中国、印度和印度尼西亚等重要的新兴强国。 At a time when the region is building a more mature security and economic architecture to promote stability and prosperity, U.S. commitment there is essential. It will help build that architecture and pay dividends for continued American leadership well into this century, just as our post-World War II commitment to building a comprehensive and lasting transatlantic network of institutions and relationships has paid off many times over — and continues to do so. The time has come for the United States to make similar investments as a Pacific power, a strategic course set by President Barack Obama from the outset of his administration and one that is already yielding benefits. 在亚太地区建设一个更成熟的安全和经济架构以增进稳定和繁荣之时，美国对这个地区的承诺至关重要。这将有助于建立起上述架构，同时使美国受益，让我们在整个世纪继续发挥领导作用，正如我国在二战过后致力于建立一个全面、持久的跨大西洋的机构和关系网络的努力已获得多倍收益，而且我们还在继续受益。现在正是美国作为一个太平洋大国作出同样投入的时候，这条战略路线是巴拉克·奥巴马总统在本届政府就任之初便确定的，现在已经产生效益。 With Iraq and Afghanistan still in transition and serious economic challenges in our own country, there are those on the American political scene who are calling for us not to reposition, but to come home. They seek a downsizing of our foreign engagement in favor of our pressing domestic priorities. These impulses are understandable, but they are misguided. Those who say that we can no longer afford to engage with the world have it exactly backward — we cannot afford not to. From opening new markets for American businesses to curbing nuclear proliferation to keeping the sea lanes free for commerce and navigation, our work abroad holds the key to our prosperity and security at home. For more than six decades, the United States has resisted the gravitational pull of these “come home” debates and the implicit zero-sum logic of these arguments. We must do so again. 由于伊拉克和阿富汗仍处于过渡时期，我们本国也面临着严重的经济挑战，美国政坛上有些人叫我们不要重新定位，而是掉头回家。他们寻求减少我们的国外参与，主张优先解决紧迫的国内问题。这些冲动是可以理解的，但也是受到误导的。那些说我们不能再继续参与全球事务的人完全是本末倒置——不参与的后果远非我们所能承受。从为美国企业打开新市场到遏制核扩散，再到保持商务和航运的自由通行，我们在国外的工作正是我们国内繁荣和安全的关键所在。60多年来，美国顶住了此类“回家”论调的牵引力和这些论点所隐含的零和逻辑。我们必须再次这样做。 Beyond our borders, people are also wondering about America’s intentions — our willingness to remain engaged and to lead. In Asia, they ask whether we are really there to stay, whether we are likely to be distracted again by events elsewhere, whether we can make — and keep — credible economic and strategic commitments, and whether we can back those commitments with action. The answer is: We can, and we will. 在我们的边界之外，人们也在揣测美国的意图，不知道我们是否愿意继续参与并发挥领导作用。在亚洲，他们问我们是否真的会长期驻留，我们是否有可能再次因别处发生的事件而转移注意力，我们是否能够作出——并保持——可信的经济和战略承诺，以及我们是否能够以行动来落实这些承诺。答案是：我们能够而且一定会这样做。 Harnessing Asia’s growth and dynamism is central to American economic and strategic interests and a key priority for President Obama. Open markets in Asia provide the United States with unprecedented opportunities for investment, trade, and access to cutting-edge technology. Our economic recovery at home will depend on exports and the ability of American firms to tap into the vast and growing consumer base of Asia. Strategically, maintaining peace and security across the Asia-Pacific is increasingly crucial to global progress, whether through defending freedom of navigation in the South China Sea, countering the proliferation efforts of North Korea, or ensuring transparency in the military activities of the region’s key players. 利用亚洲的增长和活力是美国的经济和战略利益的核心，也是奥巴马总统确定的一项首要任务。亚洲开放的市场为美国进行投资、贸易及获取尖端技术提供了前所未有的机遇。我国国内的经济复苏将取决于出口和美国公司开发亚洲广阔和不断增长的消费基群的能力。在战略上，无论是通过捍卫南中国海的航行自由、应对北韩的扩散问题还是确保该地区主要国家的军事活动的透明度，保障整个亚太地区的和平与安全对全球的发展越来越至关重要。 Just as Asia is critical to America’s future, an engaged America is vital to Asia’s future. The region is eager for our leadership and our business — perhaps more so than at any time in modern history. We are the only power with a network of strong alliances in the region, no territorial ambitions, and a long record of providing for the common good. Along with our allies, we have underwritten regional security for decades — patrolling Asia’s sea lanes and preserving stability — and that in turn has helped create the conditions for growth. We have helped integrate billions of people across the region into the global economy by spurring economic productivity, social empowerment, and greater people-to-people links. We are a major trade and investment partner, a source of innovation that benefits workers and businesses on both sides of the Pacific, a host to 350,000 Asian students every year, a champion of open markets, and an advocate for universal human rights. 正如亚洲对美国的未来极其重要一样，一个积极参与的美国对亚洲的未来也极其重要。该地区渴求我们的领导作用和我们的商业贸易——也许比现代史上任何时期都更迫切。我们是在该地区拥有一个强大的联盟网络的唯一大国，没有领土方面的野心，却有维护共同利益的长期业绩。与我们的盟友一起，我们几十年来保障了地区安全——在亚洲的海上航道巡逻并维护稳定——这反过来又帮助创造了经济增长的条件。我们通过刺激经济生产力、 增进社会权益及扩大人民与人民之间的联系，已经帮助整个地区数十亿人融入全球经济。我们是一个主要的贸易和投资伙伴、让太平洋两岸的工人和企业受益的创新源泉、每年接待35万亚洲学生的东道国、以及开放市场的先行者和普世人权的倡导者。 原文见 http://blog.ifeng.com/article/14789034.html
空气净化瓦 一句话评价：除了阳光之外，不消耗任何能量。 如何应对日益严重的环境尤其是空气污染，可以说让人们费尽了心力与财力。而下面这项简单有效的创新或许提供了一些新的思路。 借助一系列创新的化学处理，常见的瓷砖瓦片就可以由普通的标准建材让沉默不语的建筑们一跃成为对抗空气污染的超级武器：碳化硼铝瓦片外层涂有的二氧化钛，能够与烟雾中的氮氧化物粒子发生反应，并将其中和。而最终产生的副产品亦是无害的，借助雨水便可冲洗干净。与其他防污手段相比，这种巧妙而简易的化学净气法绝对是最优秀的：它无需调用机械，不必安装设备，除了阳光之外，不消耗任何能量。 The 10 Most Innovative Tech Products of 2011 BoralPure Smog-Eating Tile Using some creative chemistry, Boral Roofing has turned a standard building material into a formidable weapon—not just against sun and rain, but also air pollution. The tile's coating contains TiO2 (titanium dioxide), which reacts with and neutralizes NO X (nitrogen oxide) particles in smog. The byproduct is a harmless precipitate that accumulates on the roof and washes away in the rain. That's pollution removal at its best. No machinery. No moving parts. No energy input other than sunlight. Just a clever, air-cleansing chemical reaction. (Price: approximately $650 more than a standard 2500-sq.-ft. tile roof) Read more: The 10 Most Innovative Tech Products of 2011 - Popular Mechanics 空气净化瓦
http://www.the-scientist.com/blog/display/57686/ News: Top 7 hidden jewels Posted by Megan Scudellari View comments(2) | Comment on this news story #1 Long fingers, long toes Darwin suggested that bipedal locomotion allowed our hands to evolve the necessary dexterity for tool handling, but a new study proposes that human hands and feet coevolved: Selection on the toes led to parallel changes in the hands. Photo by Pierre79, Wikimedia Commons C. Rolian et al., The coevolution of human hands and feet, Evolution, 64:1558-68, 2010. Eval by Daniel Weinreich and David Rand, Brown University. ID: 4935958 #2 New targets for hypertension Mice lacking the ability to oxidize fatty acids do not develop abnormally high blood pressure in the arteries of the lungs, suggesting new potential therapeutic targets for hypertension. G. Sutendra et al., Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension, Sci Transl Med, 2:44ra58, 2010. Eval by Vincenzo Lionetti and Fabio Recchia, New York Medical College. ID: 4956956 #3 Feeling blue, seeing gray A new study points to a possible objective medical test for depression: Depressed patients, medicated or not, are less able to detect contrast between colors. E. Bubl et al., Seeing gray when feeling blue? Depression can be measured in the eye of the diseased, Biol Psychiatry, 68:205-8, 2010. Eval by Eric Stone, New York University Langone School of Medicine. ID: 4916985 #4 Chaperones speed evolution E. coli proteins dependent on molecular chaperones for correct folding are buffered from the detrimental consequences of misfolding-related mutations, allowing them to evolve up to 35 percent faster than other proteins. D. Bogumil and T. Dagan, Chaperonin-dependent accelerated substitution rates in prokaryotes, Genome Biol Evol, 2:602-8, 2010. Eval by William Martin, University of Duesseldorf, Germany. ID: 4886956 #5 Animal extremists pose risk The public is misinformed about the realities and importance of animal testing, a review article argues, and scientists conducting the research should play a bigger role in correcting this misunderstanding. D.L. Ringach and J.D. Jentsch, We must face the threats, J Neurosci, 29:11417-8, 2009. Eval by Matteo Carandini, University College London; S. Murray Sherman, University of Chicago, et al. (17 evaluators). ID: 1164890 #6 Silencing sequencing noise Despite the advantages of RNA sequencing technologies, many RNA-seq studies aren't rigorously designed to separate valuable data from technical noise. Appropriate statistical designs can be used to insure accuracy. P.L. Auer and R.W. Doerge, Statistical design and analysis of RNA sequencing data, Genetics, 185:405-16, 2010. Eval by Stuart Macdonald, University of Kansas. ID: 4930969 #7 Making synthetic antibodies Synthetic antibodies can be generated with affinities comparable to those of natural antibodies, but only using the right amino acids, according to new data. S. Birtalan et al., The functional capacity of the natural amino acids for molecular recognition, Mol Biosyst, 6:1186-94, 2010. Eval by Gideon Schreiber, Weizmann Institute of Science, Israel. ID: 4916956 The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period (as of September 9, 2010) on Faculty of 1000 among Hidden Jewel journals, defined as those that are less obvious. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com. Related stories: Top 7 papers in neuroscience Top 7 immunology papers Read more: Top 7 hidden jewels - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/blog/display/57686/#ixzz0zeH0orxb
http://www.the-scientist.com/blog/display/57606/ News: Top 7 hidden jewels Posted by Jef Akst View comments(2) | Comment on this news story #1 Malfunctioning microtubules Disruption to cellular microtubules during development had the surprising result of increasing the mechanical stiffness of frog embryos, leading to morphological defects and suggesting microtubules play an even more crucial role in cell movement and shape. J. Zhou, et al., Macroscopic stiffening of embryonic tissues via microtubules, RhoGEF and the assembly of contractile bundles of actomyosin, Development , 137(16):2785-94, 2010. Eval by John Wallingford, University of Texas at Austin. #2 Crucial carbon compounds Image of the mitotic spindle in a human cell showing microtubules in green, chromosomes in blue, and kinetochores in red. Image: Wikimedia commons, Afunguy By analyzing genes expressed by a coastal ocean bacterial community, the authors identify compounds that may be critical to the flow of organic carbon in the seawater and provide a novel way to study the function of marine bacteria in global carbon cycling. R.S. Poretsky, et al., Transporter genes expressed by coastal bacterioplankton in response to dissolved organic carbon, Environ Microbiol , 12(3):616-27, 2010. Eval by John Hobbie, The Ecosystems Centre. #3 Say no to natural drugs Additional sources of synthetic small molecules may be required to target all the root causes of human disease. New findings show that small-molecule natural products target proteins with more protein-protein interactions than is typical of disease gene products, suggesting that natural products may not be the most suitable starting points for targeting many proteins linked to disease. V. Danck, et al., Distinct biological network properties between the targets of natural products and disease genes, J Am Chem Soc , 132(27):9259-61, 2010. Eval by David Triggle, SUNY at Buffalo. #4 How muscles grow Researchers unraveled the mechanism of an important regulator of skeletal muscle development, mammalian target of rapamycin (mTOR). They found that it acts by controlling the transcription of a muscle-specific microRNA known as miR-1 during the differentiation of muscle precursor cells and skeletal muscle regeneration. Y. Sun, et al., Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis, J Cell Biol , 189(7):1157-69, 2010. Eval by Denis Guttridge, Ohio State University. #5 Animal extremists pose risk The public is misinformed about the realities and importance of animal testing, a review article argues, and that the scientists conducting the research should play a bigger role is correcting this misunderstanding. D.L. Ringach and J.D. Jentsch, We must face the threats, J Neurosci , 29(37):11417-8, 2009. Eval by Matteo Carandini, University College London, S. Murray Sherman, University of Chicago, et al. (17 evaluators). #6 Nameless flowers The number of flowering plants is 10 to 20 percent higher than the current number of documented species, identifying an important source of biodiversity that remains to be discovered. L.N. Joppa, et al., How many species of flowering plants are there? Proc Biol Sci , Epub 2010 Jul 7. Eval by Navjot Sodhi, National University of Singapore. #7 Most important plant patents A few of the nearly 2,000 patents in the field of plant transgenic technology are likely the most significant, according to the review, which highlights new advancements and novel approaches in the field, including a number of inventions that engineer plants for higher stress tolerance. X. Yin and Z.J. Zhang, Recent patents on plant transgenic technology, Recent Pat Biotechnol , 4(2):98-111, 2010. Eval by Ramon Serrano, Universidad Politecnica de Valencia-CSIC, Spain. The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period (as of July 29) on Faculty of 1000 among Hidden Jewel journals, defined as those that are less obvious. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com. Related stories: Top 7 papers in neuroscience Top 7 immunology papers Top 7 cell biology papers Top 7 biochemistry papers Read more: Top 7 hidden jewels - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/blog/display/57606/#ixzz0vaXYQZoc
http://f1000biology.com/top10/jewels/ 1 Exceptional F1000 Factor 13.8 Confirmation Hypothesis New Finding Controversial We must face the threats. Ringach DL, Jentsch JD J Neurosci 2009 Sep 16 29 (37):11417-8 Selected by | MatteoCarandini / S. MurraySherman / Michele A.Basso / JohnReynolds / AndrewKing / Richard GMMorris / PeterKnig / CorinnaDarian-Smith / MarinaPicciotto / RogerLemon / Kevan A.Martin / Jose-ManuelAlonso / WendySuzuki / Douglas Ruff and BevilConway / AlainDestexhe / VivienCasagrande / BruceCumming First evaluation 21Sep2009 | Latest evaluation 11Nov2009 2 Must Read F1000 Factor 6.4 Hypothesis Controversial Four stages of a scientific discipline; four types of scientist. Shneider AM Trends Biochem Sci 2009 May 34 (5):217-23 Selected by | EtienneJoly / Armen Mulkidjanian and MichaelGalperin First evaluation 3Aug2009 | Latest evaluation 10Aug2009 3 Exceptional F1000 Factor 9.0 New Finding Functional recovery after lesion of a central pattern generator. Sakurai A, Katz PS J Neurosci 2009 Oct 21 29 (42):13115-25 Selected by | SergeRossignol Evaluated 8Jan2010 4 Recommended F1000 Factor 3.0 Tech Advance Tape-Arabidopsis Sandwich - a simpler Arabidopsis protoplast isolation method. Wu FH, Shen SC, , Chan MT, Lin CS Plant Methods 2009 5 :16 Selected by | JuliaKehr Evaluated 4Jan2010 5 Must Read F1000 Factor 6.0 Hypothesis New Finding Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Xu J, Watts JA, , Zaret KS, Smale ST Genes Dev 2009 Dec 15 23 (24):2824-38 Selected by | Cheng-MingChiang Evaluated 5Jan2010 6 Recommended F1000 Factor 3.0 Tech Advance Quantitative phenotyping via deep barcode sequencing. Smith AM, Heisler LE, , Giaever G, Nislow C Genome Res 2009 Oct 19 (10):1836-42 Selected by | Tao Xu and AnujKumar Evaluated 23Dec2009 7 Must Read F1000 Factor 6.0 New Finding Non-sequence-specific interactions can account for the compaction of proteins unfolded under native conditions. Kohn JE, Gillespie B, Plaxco KW J Mol Biol 2009 Nov 27 394 (2):343-50 Selected by | KunihiroKuwajima Evaluated 13Jan2010 8 Exceptional F1000 Factor 9.0 Hypothesis New Finding A novel membrane fusion-mediated plant immunity against bacterial pathogens. Hatsugai N, Iwasaki S, , Nishimura M, Hara-Nishimura I Genes Dev 2009 Nov 1 23 (21):2496-506 Selected by | EricLam Evaluated 11Jan2010 9 Must Read F1000 Factor 6.0 Hypothesis New Finding Interneurons produced in adulthood are required for the normal functioning of the olfactory bulb network and for the execution of selected olfactory behaviors. Breton-Provencher V, Lemasson M, Peralta MR, Saghatelyan A J Neurosci 2009 Dec 2 29 (48):15245-57 Selected by | MichaelEhlers Evaluated 11Jan2010 10 Must Read F1000 Factor 6.0 Confirmation The nature of cell-cycle checkpoints: facts and fallacies. Khodjakov A, Rieder CL J Biol 2009 8 (10):88 Selected by | TomoyukiTanaka Evaluated 12Jan2010
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