B.J.Zhu, H.Yan, Y.Zhong, J.K.Chen, Y.F.Du, H.H.Cheng, Dave.A.Yuen, Relativistic HPIC-LBM and its Application in Large Temporal-spatial Turbulent Magnetic Reconnection. Part I. Model Development and Validation. Applied Mathematical Modelling. https://doi.org/10.1016/j.apm.2019.09.043 B.J.Zhu, H.Yan, Y.Zhong, J.K.Chen, Y.F.Du, H.H.Cheng, Dave.A.Yuen, Relativistic HPIC-LBM and its application in large temporal-spatial turbulent magnetic reconnection. Part II. Role of turbulence in the flux rope interaction. Applied Mathematical Modelling. https://doi.org/10.1016/j.apm.2019.05.027 衷心感谢2015.7~至今 国家超算中心广州中心天河二号各位老师的支持和帮助! 楼的地基框架、基础有了(RHPIC-LBM),可以考虑盖楼的事儿了(LTSTMR)!
I would ignore the poor title. Some Asians' college strategy: Don't check 'Asian' http://news.yahoo.com/asians-college-strategy-dont-check-asian-174442977.html
NATURE METHODS APPLICATION NOTES e-UPDATE: 09 November 2010 Now available at: http://links.ealert.nature.com/ctt?kn=1m=35969874r=Mzg0ODUxNzc1OQS2b=2j=ODYyOTMwNTcS1mt=1rt=0 Application Notes bring you the latest information about innovative tools and technologies and their applications in the lab. We hope that you will find this service useful and informative and encourage you to sign up for future Updates to ensure that you never miss one! Register to continue receiving Application Notes e-Updates: http://links.ealert.nature.com/ctt?kn=20m=35969874r=Mzg0ODUxNzc1OQS2b=2j=ODYyOTMwNTcS1mt=1rt=0 ===================================================================== -------------------------------------------- FEATURED APPLICATION NOTE: CAPROTEC -------------------------------------------- Capture Compounds for the functional isolation of nucleotide interacting proteins www.caprotec.com/ The innovative Capture Compound mass spectrometry (CCMS) technology allows the functional reduction of biological sample complexity. Small synthetic molecules (Capture Compounds(TM)) are used to interrogate native and even transmembrane proteins. Using nucleotide derivates as bait molecules allows discovery, isolation and profiling of interacting proteins from complex biological samples. Nucleotide-derived Capture Compounds are available as ready-to-use caproKits(TM) for proteomic research. http://links.ealert.nature.com/ctt?kn=8m=35969874r=Mzg0ODUxNzc1OQS2b=2j=ODYyOTMwNTcS1mt=1rt=0 ---------------------- LOT - Oriel ---------------------- Analyzing signaling pathway activity in FFPE tissue sections for cancer research and drug development www.lot-oriel.com/ Simultaneously image and quantify multiple cancer markers using immunohistochemistry (IHC) or immunofluorescence (IF) http://links.ealert.nature.com/ctt?kn=16m=35969874r=Mzg0ODUxNzc1OQS2b=2j=ODYyOTMwNTcS1mt=1rt=0 ---------------------- Epicentre Biotechnologies ---------------------- Novel methods for rRNA removal and directional, ligation-free RNA-seq library preparation www.epibio.com/ Existing library preparation methods for deep sequencing of mRNA (mRNA-seq) are time-consuming, multistep processes that are dependent on intact (nondegraded) total RNA samples, efficient removal of ribosomal RNA (rRNA), ligation of platform-specific adaptors, and multiple clean-up steps to generate di-tagged cDNA. We describe novel methods for rRNA removal from intact and fragmented RNA (Ribo-Zero(TM) technology) and for rapid preparation of directional, di-tagged mRNA-seq libraries (ScriptSeq(TM) technology), which together address the shortcomings of existing mRNA-seq library preparation workflows. http://links.ealert.nature.com/ctt?kn=5m=35969874r=Mzg0ODUxNzc1OQS2b=2j=ODYyOTMwNTcS1mt=1rt=0 ---------------------- ReGenX Biosciences ---------------------- ReGenX AAV Vector Technology: a tool for in vivo screening www.regenxbio.com/ Transgenic and knockout mice have been used to create disease models and understand gene function. However, such mice are complex to create, breeding colonies must be established, and some models are not viable. Somatic gene transfer with vectors such as adeno-associated virus (AAV) can overcome these limitations. ReGenX's AAV Vector Technology gives extremely efficient and stable gene expression in neonatal and adult animals, and can be used to create disease models and to study gene function and target validation. http://links.ealert.nature.com/ctt?kn=6m=35969874r=Mzg0ODUxNzc1OQS2b=2j=ODYyOTMwNTcS1mt=1rt=0 ---------------------- OLINK Bioscience ---------------------- Visualization and quantification of protein-protein interactions in cells and tissues www.olink.com/ Olink Bioscience has developed a protein detection assay that allows precise detection and quantification of proteins, protein interactions and modifications in fixed cells and tissue samples. Duolink(R) immunoassay reagents are based on in situ proximity ligation assays (PLA(TM)), and the assay reports proteins or protein complexes as countable distinct fluorescent or chromogenic spots visualized by standard microscopy. This allows for robust validation of protein-interaction data to show an interaction in the correct cellular context at physiologically relevant expression levels. http://links.ealert.nature.com/ctt?kn=17m=35969874r=Mzg0ODUxNzc1OQS2b=2j=ODYyOTMwNTcS1mt=1rt=0 ---------------------- Accuri Cytometers ---------------------- Expanding fluorescence detection options with the Accuri(R) C6 Flow Cytometer(R) System www.accuricytometers.com/ The innovative design of the Accuri C6 Flow Cytometer System combines usability and versatility. With Accuri's new Selectable Lasers Module, the numerous fluorophore combinations that the C6 can detect are further expanded through the use of alternative optical filters and adjustable detector-laser associations. Here we demonstrate the increased versatility by using alternative filters and selectable lasers to optimize the detection of specific fluorophore and fluorescent protein combinations. http://links.ealert.nature.com/ctt?kn=19m=35969874r=Mzg0ODUxNzc1OQS2b=2j=ODYyOTMwNTcS1mt=1rt=0 ---------------------- nanoink ---------------------- Direct deposition of micro- and nanoscale hydrogels using Dip Pen Nanolithography (DPN) www.nanoink.net Dip Pen Nanolithography(R) (DPN(TM)) is the controlled delivery of material from nanoscale tips to a surface. Its advantages over other lithography techniques include low operating costs, high resolution, nanoscale registry and multiplexed deposition capabilities. With NanoInk's latest nanolithography tools and new biocompatible patterning protocols, any scientist can easily and rapidly create arbitrary hydrogel patterns with subcellular feature sizes to be used for cell adhesion, cell migration and drug delivery studies. http://links.ealert.nature.com/ctt?kn=18m=35969874r=Mzg0ODUxNzc1OQS2b=2j=ODYyOTMwNTcS1mt=1rt=0
NATURE METHODS APPLICATION NOTES e-UPDATE: 10 June 2010 Now available at: http://links.ealert.nature.com/ctt?kn=1m=34967645r=Mzg0ODUxNzc1OQS2b=2j=NzUzOTM4OTMS1mt=1rt=0 Application Notes bring you the latest information about innovative tools and technologies and their applications in the lab. We hope that you will find this service useful and informative and encourage you to sign up for future Updates to ensure that you never miss one! Register to continue receiving Application Notes e-Updates: http://links.ealert.nature.com/ctt?kn=20m=34967645r=Mzg0ODUxNzc1OQS2b=2j=NzUzOTM4OTMS1mt=1rt=0
NATURE METHODS APPLICATION NOTES e-UPDATE: 13 May 2010 Now available at: http://links.ealert.nature.com/ctt?kn=1m=34881053r=Mzg0ODUxNzc1OQS2b=2j=NzM2NTE2MzAS1mt=1rt=0 Application Notes bring you the latest information about innovative tools and technologies and their applications in the lab. We hope that you will find this service useful and informative and encourage you to sign up for future Updates to ensure that you never miss one! Register to continue receiving Application Notes e-Updates: http://links.ealert.nature.com/ctt?kn=21m=34881053r=Mzg0ODUxNzc1OQS2b=2j=NzM2NTE2MzAS1mt=1rt=0
Now, lets plant some seeds, which is a list put together by the student, his parents, and his counselor, for colleges that match the students needs. This list will grow first (expanding), and then shrink down to 6-8 schools for the student to actually apply. Mr. Obenchain started to introduce 15 colleges, most of them I never heard of. He would briefly go over each of them. My son wrote down the name of each school on a pink paper in the left column. To the right of the pink paper, there is a column for Admission odds*. The * is noted at the bottom of the paper for codes to be used for this column: (L) for Likely (90-95% likelihood of acceptance), (P) for Probably (75%), (C) for Core (50% likelihood), and (R) for Reach (5-50% likelihood). Then, Mr. Obenchain took out a crystal ball, a 3-inch-thick Data Book, a binder that lists all the colleges with enough (to be statistically meaningful) Punahou students admitted during 2006-2009. Each page is for a college, say UW (U. of Washington). The far-left column lists from top to bottom GPAs (in a descending order), 4.0, 3.75, 3.5, etc. The second column shows the data for students admitted each year, so each 9 represents one student admitted in 2009. To the right, there is a column showing the number of applicants who were declined and the (likely) reasons. So, for the same GPA (usually at the lower end of admitted), one could be rejected. At the bottom of each page, three SAT score ranges are given for the middle 50% accepted by the college. This info is available to the public at the College Board Web site. Mr. O would show the page, say for Lawrence Univ. We can tell what the range of GPAs is for Punahou students admitted by Lawrence in the past, which GPAs may be too low, and the schools middle 50% SAT. My son would be asked to pick a code for his chance/odds to be accepted by this school. At the end of this exercise, I saw mostly L and two C on the pink paper. There was not even one R. The reason is the person who selected these seeds knew my son well not to add, say Yale, on the list. Then, Mr. O showed us how to grow the list using Naviance , which helps to track each students progress on college application. My son logged into his account, and there is a list of schools selected by his father and his counselor. Yes, parents have access to this account to keep an eye on their child, so does the college counselor. The system offers lots of tools and info. Mr. O quickly showed us how to tell if the school is a teaching college or research type. For each school on my sons list, the system will recommend a list of similar schools. So, one can spend lots of time surfing Naviance (To be continued.)
Before I move on to selecting colleges for my son (or yours), lets talk about Punahous philosophy of Good Match Appropriate Fit. I want to first cite something from Punahous college counseling Web site: Punahou seeks to provide both students and parents with the best information on college choices and admission requirements to aid in the application process. Its college counseling philosophy is to stress the importance of focusing on a 'good fit', rather than what some may call a 'good school'. Yes, this concept may be new to many Chinese parents, including myself, but please try to consider it. I thought my aunt was great at saying: Marriage is like fitting shoes to your feet. They may look pretty, but only you know how well they fit you. Well, I am not sure she discovered that by herself, but here is a quote you may have heard yourself. The shoe that fits one person pinches another by Carl_Jung (Swiss psychologist; 1875-1961). One of the take-home brochures from Punahou is College Quest 101: Finding the schools that fit me. In this brochure, it lists Parent/Guardians Role as Give ownership of the process to the student Withhold judgment Stress good fit, not good reputation In short, the pertinent question for the student in high school is not Can I get into X College? but rather, Will I be happy and successful at X College? (To be continued.)
Lets talk about SAT . Many years ago, I reconnected with a grade school classmate. She told me that her only son got 2400 on SAT. Hearing silence over the phone line, she asked me if I knew about SAT. I said I only knew SAT is a test used for college admission but had no idea about the score itself. Well, 800 is the perfect score for each component of the test, and SAT (reasoning) test has three parts: reading, math, and writing. So, her son had a perfect SAT test score! I hear more about SAT scores since then. My son also took PSAT, twice, as required and paid for by his school, and finally his first SAT last December on his 17th birthday. What I learned from Mr. Obenchain is how college admission offices view SAT vs. GPA. He added two more numbers to the Bell Curve he draw for the GPA: 500 and 600s. These are the corresponding cutoffs for each SAT component, say math. These two numbers are matched with the two GPAs, 3.0 and 3.6 (see Part 2 of my Blog), namely 500 and 3.0 are for below average. Mr. Obenchain pointed out that my sons SAT scores are closer to the high cutoff than his GPA. What does this mean? Since SAT measures ones (reasoning) ability and GPA reflects ones efforts, higher SAT than GPA suggests laziness. Well, I knew my son was not doing his best, and now Mr. O sees that, too. The college admission office will see it as well! Unlike the Gao Kao in China, SAT can be taken many times. However, statistics show that scores dont change much for the same student when he takes SAT many times, at least for U.S. students. My son was encouraged to take it one more time, since his writing score was much lower than expected (based on his PSAT, which is not part of the application package). Then, Mr. O said writing is all about grammars. Since teachers in the U.S. dont teach grammars any more, you can imagine how good the students do in SAT. (On the other hand, SAT Prep classes can really boost writing score. Punahou offers SAT Prep, for about $600. I definitely would recommend it to other parents.) At that point, Mr. O asked my son to sign on to his SAT account, and helped him to input some important data. This will ensure that when I register him for the 2nd SAT, all his scores will be collected in the same place for college admission offices to view. What if my son gets a better writing score next time, but slips on his reading? Dont worry, Mr. O said. The admission picks the higher score for each component. There are SAT subject tests, too. I guess only those very motivated students will go for it. There is also ACT (American College Test). Some students do better at ACT since it does not panelize for wrong answers. Mr. O does not recommend my son to take ACT since his SAT scores are strong already. So, I will sign him up for the June SAT, and use October as the safety net in case the June test date does not work out for some reason. (To be continued.)
Lets first talk about grades, GPA (Grade Point Average). GPA is a numerical way to describe how well a student did in class. Each letter grade has a numerical equivalent: A=4, B=3, C=2, and so forth. Punahou School GPA can be viewed online. Mr. Obenchain draw a Bell Curve, with two cutoff values of 3.0 and 3.6 clearly marked. If a students GPA is less than 3.0, then he is below average. Lets say my son is an average student, like most of his classmates. For these average students, the college admission officer may look at his GPA in two ways: annual average for each year, and the trend. If a students annual-average GPA increases in time, then the trend is positive. This is a good thing. Mr. Obenchain also examined my sons course selection for his senior year, noted two AP courses listed. Another good thing (but these courses require HARD work to get decent grades). Mr. O pointed out one thing that is missing from my sons senior year course sheet: college applications. It takes time to complete each package, and my son is asked to apply to 6-8 schools. (I hope he will apply to 3-4 schools.) The difficult part of each package is the essay, because each school has its own requirement. My son was told to spread the workload of writing essays evenly throughout the school year, and I hope he will remember this excellent piece of advice. It will be good for my son to get even higher GPA for the senior year, to keep the positive trend. There will be a Deans Letter for each student that goes to the colleges admission office. How is the letter written? Well, the letter will be based on the students own voices (through his own writing), drafted by the counselor, revised many times, and finalized by the dean. (Each grade from 9th to 12th, there are two deans who will follow these students through their high school years. Each student is assigned to one of the deans, but he is free to go to any dean if he has an issue to discuss. I am not sure he can fire his dean.) (To be continued.)
There are 4,000 colleges and universities in the U.S. to choose from... Where will my only child be in the fall of 2011? I have no experience in terms of helping a child to apply for colleges in the U.S. Am I nervous about the process? Not really. This is because I am counting on Punahou_School , the largest independent school in the States, to guide us through the process. There are about 430 graduates each year, guided by 8-10 college counselors. Not all college counselors are very good, as I was told. However, my son is very lucky, because his counselor, Mr. Obenchain, is the best. I can tell you Mr. O is a great college counselor after having spent 90 mins with him and my son this morning (yes, on April Fools Day, but this Blog is no joke). My son and I have spent very limited time talking about colleges, often on our way to school in the morning when he is willing to chat or listen. However, he has had a semester on college application, and I have attended an evening meeting at Punahou for juniors parents. (I was going to Blog about that meeting, but didnt get to.) I had a list of questions, and my son had some questions, too, for todays meeting. Some background info first: Each student has submitted many pieces of writing about himself, what he wants for college life, etc. So, the counselor knows (probably better than the parents) what the student has been thinking (or daydreaming). Mr. Obenchain intended to cover four areas during the meeting, and he did very well. They are: 1) Transcripts (more important than SAT scores), including annual averages and trend; 2) SAT test scores; 3) Seed of colleges (a list of colleges to start with, which will grow and then shrink to 6-8 at the end of the process); 4) $$$$$ (how much does it cost). I will go over each in more details. So, stay tuned