可控制癌症基因开关的分子首次合成 http://news.sciencenet.cn/htmlnews/2010/9/238029.shtm http://www.nature.com/nature/journal/vnfv/ncurrent/abs/nature09504.html http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi Start A-Literature C-Literature B-list Filter Literature A-query: bromodomain C-query: Epigenetic proteins The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 25 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here . The results of this search are saved under id # 9291 and can be accessed from the start page after you leave this session. There are 264 terms on the current B-list ( 151 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms. job id # 9291 started Mon Sep 27 02:24:36 2010 Max_citations: 50000 Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed Ngram_max: 3 9291 Search ARROWSMITH A A_query_raw: bromodomain and extra-terminal Mon Sep 27 02:26:23 2010 A query = bromodomain and extra-terminal started Mon Sep 27 02:26:24 2010 A query resulted in 4 titles 9291 Search ARROWSMITH A A_query_raw: bromodomain Mon Sep 27 02:27:26 2010 A query = bromodomain started Mon Sep 27 02:27:26 2010 A query resulted in 361 titles 9291 Search ARROWSMITH C C_query_raw: Epigenetic proteins Mon Sep 27 02:27:35 2010 C: Epigenetic proteins 9242 A: pubmed_query_A 361 AC: ( bromodomain ) AND ( Epigenetic proteins ) 25 C query = Epigenetic proteins started Mon Sep 27 02:27:35 2010 C query resulted in 9242 titles A AND C query resulted in 25 titles 1547 B-terms ready on Mon Sep 27 02:28:26 2010 Sem_filter: Genes Molecular Sequences, and Gene Protein Names 264 B-terms left after filter executed Mon Sep 27 02:29:44 2010 B-list on Mon Sep 27 02:33:10 2010 1 e2f 2 wnt 3 mecp2 4 zinc finger protein 5 brca1 6 stat3 7 cancer testis antigen 8 swi snf 9 gcn5 10 interferon regulatory factor 11 sp1 12 ash1 13 kap1 14 creb binding protein 15 swi2 16 pcaf 17 mll 18 iswi 19 aurora b 20 retinoic acid receptor 21 chromatin remodeling 22 cbp 23 histone acetyltransferase 24 swi 25 h2ax 26 p300 27 creb 28 gene promoter 29 homeotic gene 30 eralpha 31 transporter gene 32 homeotic 33 c myc 34 myod 35 pml 36 brg1 37 hdac1 38 testis specific 39 histone acetylation gene 40 tif1alpha 41 p tefb 42 tefb 43 rdna 44 chaperone 45 e2f-1 46 rna polymerase i 47 containing gene 48 mek 49 acetylation gene 50 histone deacetylase 51 repressor 52 cbp p300 53 exon 54 snf 55 prb 56 phd finger 57 myb 58 genome reprogramming 59 transcription factor 60 histone h4 61 e2f1 62 genome wide 63 norc 64 e1a 65 tata binding protein 66 chromatin remodeling protein 67 erk 68 h2a 69 rbp2 70 novel gene 71 cyclin 72 wstf 73 snf2 74 tumor suppressor gene 75 rna polymerase 76 gene silencing 77 kap-1 78 c jun 79 ret 80 candidate tumor suppressor 81 tata 82 receptor tyrosine kinase 83 estrogen receptor 84 asf1 85 tyrosine kinase 86 myc 87 expression gene 88 ets 89 sumo 90 p53 91 dna binding 92 glycogen synthase 93 vdr 94 androgen receptor 95 intron 96 ribosomal gene 97 testis specific gene 98 tif1beta 99 oncogene 100 h2a z 101 h4 102 gene encoding 103 atf-2 104 high mobility group 105 cdna 106 brahma 107 brm 108 oncogene expression 109 glucocorticoid receptor 110 histone gene 111 tbp 112 gene chromosome 3p21 113 cell cycle progression 114 tat 115 tumor suppressor 116 nuclear localization signal 117 c fos 118 gene repression 119 bet 120 hmr 121 isoform 122 response element 123 orc 124 gene chromosome 125 gene acute myeloid 126 chromatin template 127 promoter 128 acetyltransferase 129 viral oncogene 130 ku 131 g1 132 c myb 133 gene associated 134 suppressor gene 135 rb 136 box 137 open reading frame 138 male genome reprogramming 139 reading frame 140 gene euchromatin 141 jun 142 gtpase 143 ras 144 phd 145 barr 146 genomic 147 gene involved 148 prostate cancer 149 human gene 150 nuclear protein 151 histone 152 acf
标签: 癌症基因开关
