干细胞 Stem Cell - SC 发表文献量 Publications: 39,678 | 文献被引量 Citation Count: 581,291 检索用词 Stemming Variations: Stem cells, Stems Cells, stem cellness 干细胞的概念定义 Definition Context (1) Stem cells are defined as undifferentiated cells that have the capacity to self-renew and to differentiate into various mature cells at a single cell level . Stem cells support normal embryogenesis and postnatal life. Stem cells serve to renew tissue throughout an individual’s postnatal life by replacing the cells that are lost owing to everyday wear and tear in our bodies. Bone marrow contains two types of stem cells: hematopoietic stem cell (HSC) and mesenchymal stem cells (MSCs). HSCs are able to give rise to all cells in the hematopoietic system ... Yao-Hua Song , et al. Differentiation and Plasticity of Stem Cells for Tissue Engineering 作者分布 Authors (107337) Irving L. Weissman 110 Johnny Huard 98 Mariusz Z. Ratajczak 87 Peter J. Quesenberry 75 Connie J. Eaves 74 会议信息 Conferences (101) EMBC 48 NEBEC 21 IEEE International Symposium on Biomedical Imaging 16 BMEI 11 ENBENG 10 期刊分布 Journals (2823) Nature 1047 BONE MARROW TRANSPLANT 864 PNAS 854 Plos One 657 Science 540 研究主题 Keywords (2063) Adult Stem Cell Bone Marrow Cancer Stem Cell Cell Therapy Embryonic Stem Cell Growth Factor Hematopoietic Stem Cell Human Embryonic Stem Cell Neural Stem Cell Progenitor Cell Regenerative Medicine Stem Cell Transplant Tissue Engineering embryonics mesenchymal stem cell 详细信息见 http://academic.research.microsoft.com/Keyword/68628/stem-cell
荟萃分析 meta analysis 发表文献量 Publications: 32,152 | 文献被引量 Citation Count: 647,239 Stemming Variations: meta analysis Cumulative Annual 荟萃分析的概念定义 Definition Context (5) Meta-analysis (MA) is the quantitative integration of empirical studies that address the same or similar issues. It provides overall estimates of ef fect size, and can thus guide practical application of research findings. It can also identify moderati ng variables, and thus contribute to theorybuilding and research planning. It overcomes many o f the disadvantages of null hypothesis significance testing... Geoff Cumming . META-ANALYSIS: PICTURES THAT EXPLAIN HOW EXPERIMENTAL FINDINGS CAN BE ... Meta-analysis is a statistical procedure to do syntheses of evidences. In the production of scientific knowledge, in spite of paradigmatic skips of quality, the rising of the accumulation of acquired knowledge (based in camed studies) is, in the general, the way as science moves forward to accomplish new discoveries and to confirm other already obtained. The methods developed for the attainment of the meta-analysis, analysis of analyses previously accomplished, have been developed during this century... Paulo Alfonso Bracarense Costa , et al. Fuzzy approach to meta-analysis Meta-analysis is a systematic review of a focused topic in the literature that provides a quantitative estimate for the effect of a treatment intervention or exposure. The key to designing a high quality meta-analysis is to identify an area where the effect of the treatment or exposure is uncertain and where a relatively homogenous body of literature exists. The techniques used in meta-analysis provide a structured and standardized approach for analyzing prior findings in a specific topic in the literature... Mark W. Russo . How to Review a Meta-analysis Meta-analysis is a statistical method of synthesizing quantitative results across studies examining a common research question. This chapter discusses the logic and methods of meta-analysis with specific application to the field of criminology and criminal justice. A key feature of meta-analysis is the effect size, which encodes the study findings on a common index, such as the standardized mean difference, correlation coefficient, or odds-ratio... David B. Wilson . Meta-analysis Meta-analysis is a statistical technique that allows one to combine the results from multiple studies to glean inferences on the overall importance of various phenomena. This method can prove to be more informative than common ''vote counting,'' in which the number of significant results is compared to the number with nonsignificant results to determine whether the phenomenon of interest is globally important. While the use of metaanalysis is widespread in medicine and the social sciences, only recently has it been applied to ecological questions... Dean C. Adams , et al. Resampling Tests for Meta-Analysis of Ecological Data 作者分布 Authors (75787) Ruut Veenhoven 254 John P. A. Ioannidis 136 Alexander J. Sutton 84 Andre G. Uitterlinden (André G. Uitterlinden) 78 Matthew E. Falagas 68 会议信息 Conferences (123) HICSS 12 EMBC 7 CHI 6 FECS 4 METRICS 3 期刊分布 Journals (3800) PSYCHOL BULL 388 Plos One 338 BMJ 276 Gastroenterology 269 J APPL PSYCHOL 248 研究主题分布 Keywords (2474) Clinical Trial Confidence Interval Controlled Trial Effect Size Individual Patient Data Odd Ratio Polymorphism Publication Bias Random Effects Model Randomised Controlled Trial Randomized Controlled Trial Randomized Trial Relative Risk Systematic Review case-control study 详细信息见： http://academic.research.microsoft.com/Keyword/24994/meta-analysis
系统综述 Systematic Review 发表文献量 Publications: 26,829 | 文献被引量 Citation Count: 355,885 同义词 Stemming Variations: systematically reviews, systematically review, systematic reviews, systematically reviewed, systematic reviewers 系统综述的概念定义 Definition Context (4) A systematic review is a carefully planned and conducted study designed to answer a specific focused clinical question. A systematic review differs from the frequently encountered narrative review article. Systematic review must be completed using a prespecified methodology... Dereck L. Hunt , et al. How to read a systematic review Systematic review is a type of research that attempts to identify and summarize all of the evidence related to a specific research question... Stephen Bent , et al. The use of systematic reviews and meta-analyses in infection control a... Systematic review is a method to identify, assess and analyse published primary studies to investigate research questions... Mark Staples , et al. Experiences using systematic review guidelines Systematic reviews are defined as convenient evidential summaries for clinicians which serve as a powerful tool for patient care decisions. They are considered to be the basis for guidelines of medical practice suggesting directions for new research. These scientific reviews, constructed through well-defined methods, have key role in Evidence-Informed Health Care which means to apply new therapies and treatments, which are proved to be effective for a particular treatment by authentic and quality researches, in clinical practice... Hydrie MZ , et al. Systematic Reviews and their role in Evidence - Informed Health Care 文献的作者分布 Authors (61473) Edzard Ernst 205 Khalid Saeed Khan 102 Victor M. Montori 91 David Moher 80 Gordon H. Guyatt 71 会议信息 Conferences (111) ESEM 31 ICSE 7 SPIN 7 ICSP 4 JSAI Workshops 4 文献的期刊分布 Journals (3187) BMJ 402 VALUE HEALTH 305 Plos One 207 J CLIN EPIDEMIOL 201 AMER J GASTROENTEROL 159 文献的主要关键词（研究主题分布） Keywords (1993) Clinical Trial Confidence Interval Controlled Trial Data Extraction Literature Search Odd Ratio Outcome Measure Random Effects Model Randomised Controlled Trial Randomized Controlled Trial Randomized Trial Relative Risk Risk Factors Systematic Literature Review meta analysis 详细信息见： http://academic.research.microsoft.com/Keyword/41241/systematic-review
全球临床试验研究项目计量分析报告 ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world. ClinicalTrials.gov临床试验网 currently lists 137,539 studies 项目数量with locations in all 50 states and in 182 countries国家数量. ClinicalTrials.gov receives more than 95 million page views per month and 60,000 unique visitors daily 日访问量(as of February 2012). Contents Locations of Registered Studies Locations of Recruiting Studies Map of Studies Registered on ClinicalTrials.gov Types of Registered Studies Number of Registered Studies over Time Number of Registered Studies with Posted Results over Time Locations of Registered Studies This chart shows the distribution of locations for all studies registered on ClinicalTrials.gov. Total N = 137,539 studies (Data as of December 18, 2012) Legend for Recruiting Study location pie chart image Pie Color Location Non-U.S. Only (43%) U.S. Only (41%) Not Specified (9%) Both U.S. Non-U.S. (6%) Distribution of locations for all studies registered on ClinicalTrials.gov" Location Number of Registered Studies and Percentage of Total Non-U.S. Only 58,698 (43%) U.S. Only 56,983 (41%) Not Specified* 12,983 (9%) Both U.S. Non-U.S. 8,875 (6%) Total 137,539 * Not Specified: The location of the study was not provided by the Sponsor. (Data as of December 18, 2012) Locations of Recruiting Studies This chart shows the distribution of locations for recruiting studies registered on ClinicalTrials.gov. Total N = 29,400 studies (Data as of December 18, 2012) Legend for Recruiting Study location pie chart image Pie Color Location Non-U.S. Only (49%) U.S. Only (45%) Both U.S. Non-U.S. (6%) Distribution of locations for recruiting studies registered on ClinicalTrials.gov Location Number of Recruiting Studies and Percentage of Total Non-U.S. Only 14,378 (49%) U.S. Only 13,118 (45%) Both U.S. Non-U.S. 1,904 (6%) Total 29,400 (Data as of December 18, 2012) To Top Map of Studies Registered on ClinicalTrials.gov See Studies on a Map for an interactive map of studies that are registered on ClinicalTrials.gov. To Top Types of Registered Studies This table shows the number and types of studies that are registered and for which results are available on ClinicalTrials.gov. (Data as of December 18, 2012) Study and intervention types with number of registered studies and with number of studies having posted results Study and Intervention Type Number of Registered Studies and Percentage of Total Number of Studies With Posted Results and Percentage of Total*** Total 137,539 7,679 Interventional 111,598 (81%) 7,159 (93%) Type of Intervention* Drug or biologic 75,606 6,133 Behavioral, other 26,611 750 Surgical procedure 12,574 293 Device** 9,490 639 Observational 25,315 (18%) 520 (6%) Expanded Access 186 N/A * A study may include more than one type of intervention (that is, a single study may be counted more than once). Because of this, the sum of counts by type of intervention do not equal the total number of interventional studies. ** A total of 440 applicable device clinical trials were submitted as "delayed posting" under the Food and Drug Administration Amendments Act of 2007 (FDAAA). That is, the Responsible Party has indicated that such a trial includes a device not previously approved or cleared by the U.S. FDA for any use. These are not included in the count of trials with at least one device. *** Results are only required to be submitted for certain trials. For example, results submission is generally not required for trials of drugs, biologics, or devices that have not been approved by FDA; observational studies; and trials completed before 2008. N/A = not applicable To Top Number of Registered Studies Over Time The graph below shows the total number of studies registered on ClinicalTrials.gov since 2000, based on the First Received Date. The first version of ClinicalTrials.gov was made available to the public on February 29, 2000. (Data as of December 18, 2012) Key ICMJE: Indicates when the International Committee of Medical Journal Editors began requiring trial registration as a condition of publication under the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (URM) (September 2005). FDAAA: Indicates when the expanded registration requirements of FDAAA began and were implemented on ClinicalTrials.gov (December 2007). Years with numbers of registered studies Year Total Number of Registered Studies 2000 5,647 2001 7,000 2002 8,598 2003 10,279 2004 12,081 2005 25,041 2006 35,984 2007 49,399 2008 66,448 2009 83,636 2010 101,356 2011 119,482 (Data as of December 18, 2012) To Top Number of Registered Studies With Posted Results Over Time The graph below shows the number of registered studies with results posted on ClinicalTrials.gov, based on the Results First Received Date. ClinicalTrials.gov launched its results database in September 2008, at which time sponsors or investigators were allowed to begin submitting results for their registered studies. The results database was developed to accommodate results submission requirements outlined in FDAAA. (Data as of December 18, 2012) Years with numbers of registered studies having posted results Year Total Number of Registered Studies With Posted Results 2009 1,795 2010 3,459 2011 5,742 (Data as of December 18, 2012) This page last reviewed in August 2012 To Top 数据来源： http://clinicaltrials.gov/ct2/resources/trends See Studies on Map Map of All Studies in ClinicalTrials.gov Click on the map below to show a more detailed map (when available) or search for studies (when map not available). Region Name Number of Studies World 137539 Africa 3094 Central America 1827 East Asia 11668 Japan 2555 Europe 36903 Middle East 5582 North America 72205 Canada 10420 Mexico 1772 United States 65858 North Asia 2530 Pacifica 3834 South America 4650 South Asia 2472 Southeast Asia 2763 Hints: Click on a link to show a map of that region Click on a link to search for studies in that region. Use the back button to return to this list and try another region. Studies with no locations are not included in the counts or on the map. Studies with multiple locations are included in each region containing locations. See Studies on Map Map of All Studies in ClinicalTrials.gov Click on the map below to show a more detailed map (when available) or search for studies (when map not available). Region Name Number of Studies World 137539 East Asia 11668 China 3434 Hong Kong 771 Korea, Republic of 3902 Mongolia 6 Taiwan 2836 Hints: Click on a link to show a map of that region Click on a link to search for studies in that region. Use the back button to return to this list and try another region. Studies with no locations are not included in the counts or on the map. Studies with multiple locations are included in each region containing locations. 数据来源： http://clinicaltrials.gov/ct2/search/map?map=ES
军事医学、灾害医学、急救医学三者关系研究信息分析报告 检索策略 ("military medicine" OR ("military" AND "medicine" ) OR "military medicine" ) AND ("medicine" OR "medicine" ) AND ("emergency medicine" OR ("emergency" AND "medicine" ) OR "emergency medicine" ) 信息分析平台 http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/AnneOTate_summarize.cgi?ID=24954t=fw=m 信息分析结果 Topics Frq 1 Military Medicine 916 2 Emergency Medical Services 511 3 Military Personnel 326 4 War 264 5 Wounds and Injuries 217 6 Emergency Medicine 169 7 Triage 141 8 Disaster Planning 131 9 Emergency Service, Hospital 125 10 Disasters 124 11 Great Britain 115 12 Transportation of Patients 113 13 Hospitals, Military 110 14 USSR 103 15 History, 20th Century 96 16 Emergency Treatment 79 17 Naval Medicine 77 18 Emergencies 75 19 Retrospective Studies 73 20 Emergency Medical Technicians 72 Important words Frq 1 military 710 2 battlefield 91 3 austere 41 4 casualty 257 5 civilian 191 6 emergency 770 7 medic 63 8 combat 191 9 katrina 6 10 afghanistan 58 11 tactical 54 12 disaster 144 13 army 138 14 iraq 56 15 triage 92 16 soldier 89 17 evacuation 127 18 tsunami 10 19 deployed 66 20 battalion 20 Author frq 1 Deuster PA 40 2 De Lorenzo RA 18 3 Smith JE 18 4 Gerhardt RT 16 5 Hodgetts TJ 16 6 Holcomb JB 16 7 Blackbourne LH 14 8 Singh A 14 9 Bebarta VS 10 10 Burkle FM 10 11 Mahoney PF 10 12 Cinar O 9 13 Hodgetts T 9 14 Nechaev EA 9 15 O'Connor FG 9 16 Poth M 8 17 Russell R 8 18 Bland SA 7 19 Deuster P 7 20 Eryilmaz M 7 Affiliations frq 1 USA 323 2 Department of Emergency Medicine 225 3 Bethesda 100 4 Uniformed Services University of the Health Sciences 76 5 Fort Sam Houston 73 6 Department of Military and Emergency Medicine 62 7 Texas 45 8 Department of Surgery 43 9 Brooke Army Medical Center 41 10 Royal Centre for Defence Medicine 36 11 San Antonio 33 12 San Diego 30 13 Ankara 27 14 Birmingham 26 15 TX 26 16 Maryland 25 17 Israel 24 18 MD 24 19 Academic Department of Military Emergency Medicine 22 20 Gulhane Military Medical Academy 22 Journals frq 1 Mil Med 278 2 Voen Med Zh 190 3 J R Army Med Corps 122 4 Ann Emerg Med 56 5 J Trauma 42 6 Aviat Space Environ Med 34 7 Prehosp Disaster Med 32 8 J Emerg Med 29 9 Acad Emerg Med 27 10 Am J Emerg Med 22 11 J Spec Oper Med 19 12 J R Nav Med Serv 17 13 Prehosp Emerg Care 17 14 Injury 14 15 Emerg Med J 13 16 US Army Med Dep J 13 17 Emerg Med Clin North Am 12 18 JAMA 11 19 Vojnosanit Pregl 11 20 Crit Care Med 9 Years 1 2012 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 2 2011 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 3 2010 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 4 2009 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 5 2008 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 6 2007 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 7 2006 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 8 2005 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 9 2004 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 10 2003 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 11 2002 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 12 2001 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 13 2000 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 14 1999 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 15 1998 xxxxxxxxxxxxxxxxxxxxxxxxx 16 1997 xxxxxxxxxxxxxxxxxxxxxxx 17 1996 xxxxxxxxxxxxxxxxxxxxxxxxxxx 18 1995 xxxxxxxxxxxxxxxxxxxxxxxxx 19 1994 xxxxxxxxxxxxxxxxxxxxxxx 20 1993 xxxxxxxxxxxxx Topics Frq Most recent articles 217 1 Emergency Medical Services 511 2 Military Personnel 326 3 War 264 4 Wounds and Injuries 217 5 Emergency Medicine 169 6 Disaster Planning 131 7 Emergency Service, Hospital 125 8 History, 20th Century 96 9 Emergency Treatment 79 10 Naval Medicine 77 11 Emergencies 75 12 Emergency Medical Technicians 72 13 Aerospace Medicine 48 14 Prospective Studies 43 15 Exercise 17 Miscellaneous 215 附件 214篇文献 pubmed_result.txt.gzip
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