Call for Papers for “Wind Power Generation” Guest Editors: Prof. Jinji GAO (高金吉院士), Beijing University of Chemical Technology Prof. Zheng YOU (尤政院士), Tsinghua University Prof. Fulei CHU (褚福磊教授), Tsinghua University Prof. Tielin SHI (史铁林教授), Huazhong University of Science and Technology Frontiers of Mechanical Engineering is an international peer-reviewed academic journal sponsored by the Chinese Academy of Engineering. The journal seeks to provide a forum for a broad blend of high-quality academic papers in order to promote rapid communication and exchange between researchers, scientists, and engineers in the field of mechanical engineering. Due to the high failure rate of large scale wind turbines, it is necessary to develop efficient maintenance strategy including dynamic modelling, condition monitoring and diagnosis tailored to wind turbine technology. The main objective of this Special Issue is to bring together ideas from the international research community, to present the latest developments, and to advance the fields of wind turbine condition monitoring. Subject Coverage We invite authors to submit original research to this Special Issue in following potential topics. The topics will include, but not limited to: ● Dynamic modelling of wind turbine ● Wind turbine condition monitoring and fault diagnosis ● Measuring and testing technique for wind turbine Notes for Prospective Authors The submitted papers should not have been previously published nor be currently under consideration for publication elsewhere. All papers are refereed through a peer review process. A guide for authors, sample copies and other relevant information for submitting papers are available on the Guidelines for Authors ( http://journal.hep.com.cn/fme ). Important Dates Submission Deadline: 15th Jul, 2016 Publication date: Dec, 2016 Manuscripts submission: http://mc.manuscriptcentral.com/fome For enquiries regarding this Special Issue please contact the editorial office Tingting Guo Xixi Chen guott@hep.com.cn fme@hust.edu.cn
Call for Papers - Journal of Chemistry (SCI-indexed, IF=0.772) Special Issue on: Recent Advances in Synthesis and Catalysis of 3D Transition Metal Oxides http://www.hindawi.com/journals/jchem/si/364648/cfp/ Call for Papers Transition metal oxides constitute a major area of catalytic materials and have been receiving widespread and continuous attention in the catalysis research community. Due to the earthbundance of 3d transition metal oxides, they are extensively used as heterogeneous catalysts or catalyst supports for noble metals in industrial catalysis for a variety of applications, such as chemical manufacturing, petroleum refinery, plastic production, and biomass upgrading. Enormous efforts have also been dedicated to the design and development of new 3d transition metal oxide‐based nanostructured materials for replacing high‐cost noble metal-based analogues. For example, morphologically controlled synthesis of 3d transition metal oxide nanostructureswith preferentially exposed crystal surfaces leads to distinct catalytic properties. It further allows for establishing a structure‐property relationship that provides deep insights in designing new catalytic materials. In addition to the applications in heterogeneous catalysis, most 3d transition metal oxides are semiconductors and exhibit significant photocatalytic properties in reactions of water-splitting, CO 2 reduction, and organic pollutants degradation. Currently, great challenges lie in the development of photocatalytic materials with high efficiency in solar energy harvesting and transformation. Synthesis and engineering of 3d transition metal oxidenanostructures with enhanced quantum efficiency offers a solution to tackle these challenges. This special issue aims to present recently developed novel synthetic strategies of 3d transition metal oxide nanostructures and their catalytic or photocatalytic applications. It is open to both original research articles and review articles. Potential topics include, but are not limited to: 1. Size and shape‐controlled synthesis of 3d transition metal oxide nanostructures 2. Synthesis and characterization of mixed transition metal oxides 3. Synthesis of microporous or mesoporous 3d transition metal oxides 4. Studies on growth mechanisms of 3d transition metal oxide nanostructures 5. Characterization of surface structures of 3d transition metal oxides in relation to catalytic properties 6. Oxygen vacancy and phase transition of 3d transition metal oxides 7. Engineering 3d transition metal oxides for improved performances in photocatalysis 8. Studies of metal‐support interaction on 3d transition metal oxides 9. In situ studies of 3d transition metal oxide based nanocatalysts under reaction conditions or during catalysis Authors can submit their manuscripts via the Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jchem/materials.chemistry/3dtm/ . Manuscript Due Friday, 23 September 2016 First Round of Reviews Friday, 16 December 2016 Publication Date Friday, 10 February 2017 Lead Guest Editor Shiran Zhang , University of Notre Dame, Notre Dame, USA Guest Editors Sihui Zhan , Nankai University, Tianjin, China Xiaoli Gu , Nanjing Forestry University, Nanjing, China Chunhua Cui , University of Zurich, Zürich, Czech Republic Zhaoyang Lin , University of California, Los Angeles, USA
http://aclweb.org/anthology/docs/mtcl.html#2600 Mechanical Translation and Computational Linguistics This listing is reproduced by permission from the Machine Translation Archive for the benefit of the computational linguistics community. To the Machine Translation Archive Home Page » Toggle Table of Contents 1968 Mechanical Translation and Computational Linguistics, Volume 11, Numbers 1 and 2, March and June 1968, published July 1970 Mechanical Translation and Computational Linguistics, Volume 11, Numbers 3 and 4, September and December 1968, published October 1970 1967 Mechanical Translation and Computational Linguistics, Volume 10, Numbers 1 and 2, March and June 1967, published January 1968 Mechanical Translation and Computational Linguistics, Volume 10, Numbers 3 and 4, September and December 1967, published Februray 1969 1966 Mechanical Translation and Computational Linguistics, Volume 9, Number 1, March 1966, published June 1966 Mechanical Translation and Computational Linguistics, Volume 9, Number 2, June 1966, published January 1967 Mechanical Translation and Computational Linguistics, Volume 9, Numbers 3 and 4, September and December 1966, published March 1967 1965 Mechanical Translation and Computational Linguistics, Volume 8, Number 2, February 1965, published April 1965 Mechanical Translation and Computational Linguistics, Volume 8, Numbers 3 and 4, June and October 1965, published October 1965 1964 Mechanical Translation, Volume 8, Number 1, August 1964, published August 1964 1963 Mechanical Translation, Volume 7, Number 2, August 1963, published September 1963 1962 Mechanical Translation, Volume 7, Number 1, July 1962, published July 1962 1961 Mechanical Translation, Volume 6, November 1961, published December 1961 1958 Mechanical Translation, Volume 5, Number 1, July 1958, published December 1958 Mechanical Translation, Volume 5, Number 2, September 1958, published July 1959 Mechanical Translation, Volume 5, Number 3, December 1958, published March 1960 1957 Mechanical Translation, Volume 4, Number 1-2, November 1957, published March 1958 Mechanical Translation, Volume 4, Number 3, December 1957, published July 1958 1956 Mechanical Translation, Volume 3, Number 1, July 1956, published August 1956 Mechanical Translation, Volume 3, Number 2, November 1956, published March 1957 Mechanical Translation, Volume 3, Number 3, December 1956, published August 1957 1955 Mechanical Translation, Volume 2, Number 1, July 1955 Mechanical Translation, Volume 2, Number 2, November 1955, published December 1955 Mechanical Translation, Volume 2, Number 3, December 1955, published April 1956 1954 Mechanical Translation, Volume 1, Number 1, March 1954 Mechanical Translation, Volume 1, Number 2, August 1954 Mechanical Translation, Volume 1, Number 3, December 1954 Mechanical Translation and Computational Linguistics, Volume 11, Numbers 1 and 2, March and June 1968, published July 1970 p.1-13 : Robert F. Simmons; John F. Burger A semantic analyzer for English sentences p.14-21 : A. Ljudskanov Is the generally accepted strategy of machine-translation research optimal? p.22-31 : Julie Beth Lovins Development of a stemming algorithm p.32-57 : Itiroo Sakai Some mathematical aspects of syntactic description Mechanical Translation and Computational Linguistics, Volume 11, Numbers 3 and 4, September and December 1968, published October 1970 p.59-72 : Yorick Wilks On-line semantic analysis of English texts p.73-74 : Joseph E. Grimes; John R. Alsop; and Alan Wares Computer backup for field work in phonology p.75-77 : David Woodhouse A note on the translation of Swahili into English p.78-88 : P. W. Culicover Paraphrase generation and information retrieval from stored text p.89-102 : D. Kathryn Weintraub The English relative clause Mechanical Translation and Computational Linguistics, Volume 10, Numbers 1 and 2, March and June 1967, published January 1968 p.1-10 : David B. Orr; Victor H. Small Comprehensibility of machine-aided translations of Russian scientific documents p.11-17 : Henrik Birnbaum Some notes on Russian predicative infinitives in automatic translation p.18-25 : L. L. Earl; B. V. Bhimani; R. P. Mitchell Statistics of operationally defined homonyms of elementary words p.26-37 : John M. Dolan A note on Quine's theory of radical translation Mechanical Translation and Computational Linguistics, Volume 10, Numbers 3 and 4, September and December 1967, published Februray 1969 p.39-52 : Robert M. Schwarcz Steps toward a model of linguistic performance: a preliminary sketch p.53-67 : Lois L. Earl Automatic determination of parts of speech of English words p.68-84 : James Gough On the German locative: a study in symbols Mechanical Translation and Computational Linguistics, Volume 9, Number 1, March 1966, published June 1966 p.2-3 : Paul L. Garvin Some comments on algorithm and grammar in the automatic parsing of natural languages p.4-9 : Jane Robinson Endocentric constructions in the Cocke parsing logic p.10-14 : Wayne A. Lea The
原文地址: http://glmigratorybirds.org/resources.html A selection of key stopover papers These papers were selected from among the Huge Stopover Bibliography to include studies of each of the bird groups (landbirds, shorebirds, and waterfowl) that (1) may be generally applicable throughout the Great Lakes region, and (2) that have been done in different parts of the Great Lakes basin. Many other papers cited in the bibliography complement the papers noted below, including detailed site-specific information that will be useful for implementing on the ground conservation strategies. Hover over the title to get a brief description of the article. Bonter, D.N., S.A. Gauthreaux, Jr., and T.M. Donovan. 2009. Characteristics of important stopover locations for migrating birds: Remote sensing with radar in the Great Lakes basin. Conservation Biology 23:440-448. Buler, J.J. and D.K. Dawson. 2014. Radar analysis of fall migration stopover sites in the northeastern U.S. The Condor Ornithological Applications 116:357-370. Diehl, R.H., R.P. Larkin, and J.E. Black. 2003. Radar observations of bird migration over the Great Lakes. The Auk 120:278-290. Dunn, E.H. 2000. Temporal and spatial patterns of mass gain of Magnolia Warblers during migration. The Auk 117:12-21. Ewert, D.N., G.J. Soulliere, R.D. Macleod, M.C. Shieldcastle, P.G. Rodewald, E. Fujimura, J. Shieldcastle, and R.J. Gates. 2006. Migratory bird stopover site attributes in the western Lake Erie basin. Final report, George Gund Foundation. Ewert, D.N., M.J. Hamas, R.J. Smith, M.E. Dallman, and S.W. Jorgensen. 2011. Distribution of migratory landbirds along the northern Lake Huron shoreline. Wilson Journal of Ornithology 123:536-547. Faaborg, J., R.T. Holmes, A.D. Anders, K.L. Bildstein, K.M. Dugger, S.A. Gauthreaux, Jr., P. Heglund, K.A. Hobson, A. E. Jahn, D.H. Johnson, S.C. Latta, D.J. Levey, P.P. Marra, C.L. Merkford, E. Nol, S.I. Rothstein, T.W. Sherry, T.S. Sillett, F.R. Thompson III, and N. Warnock. 2010. Conserving migratory land birds in the New World: Do we know enough? Ecological Applications 20:398-418. France, K.E., M. Burger, M.D. Schlesinger, K.A. Perkins, M. MacNeil, D. Klein and D.N. Ewert. 2012. Final report for Lake Ontario Migratory Bird Stopover Project. Prepared by The Nature Conservancy for the New York State Department of Environmental Conservation (Grant C303907 from the New York Great Lakes Protection Fund). Available from www.nature.org/nybirds . Lott, K.D., M. Seymour, and B. Russell. 2011. Mapping pelagic bird distribution and abundance as a decision-making tool for offshore wind turbine development and conservation planning. Available from: hyperlink Petit, D.R. 2000. Habitat use by landbirds during Nearctic-Neotropical migration routes: implications for conservation of stopover habitats. Studies in Avian Biology 20: 15-33. Potter, B.A., R.J. Gates, G.J. Soulliere, R.P. Russell, D.A. Granfors, and D.N. Ewert. 2007. Upper Mississippi River and Great Lakes Joint Venture Shorebird Habitat Conservation Strategy. U.S. Fish and Wildlife Service, Fort Snelling, MN. 101 pp. Soulliere, G.J., B.A. Potter, J.M. Coluccy, R.C. Gatti, C.L. Roy, D.R. Luukkonen, P.W. Brown, and M.W. Eicholz. 2007. Upper Mississippi River and Great Lakes Region Joint Venture Waterfowl Habitat Conservation Strategy. U.S. Fish and Wildlife Service, Fort Snelling, Minnesota, USA.
SCI论文作者甄别软件设计及应用 于健1, 吴霞2, 赵春梅2 1. 中国科学院国家科学图书馆 北京 100190; 2. 中国科学院高能物理研究所 北京 100049 Design and Application of Author Discrimination Software on Papers Indexed by SCI Yu Jian1, Wu Xia2, Zhao Chunmei2 1. National Science Library, Chinese Academy of Sciences, Beijing 100190, China; 2. Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China 摘要 结合机构产出SCI论文统计需求,设计一款自动甄别目标机构作者和实验室的软件。 可辅助论文统计部门快速准确识别机构论文作者和实验室(部门),进而获得机构作者和实验室的论文产出分布情况。 从技术上实现综合利用相同研究单元内作者合作较多的科研特点、自定义作者唯一关键词或合作者字段以及SCI数据库作者相关字段的文本特征来甄别目标机构作者。 允许用户通过目标机构人员名单维护来实现SCI论文作者甄别的自动化和高准确度。 有效解决SCI论文中文作者因拼音写法多样且易重名而造成作者相关论文数据难以准确统计的问题,其设计思路也适用于EI及其他数据库论文作者甄别。 该软件在实现甄别功能的同时也具有清理机构论文数据的功能, 排除用户目标机构名称唯一标识词输入不全的因素, 提取不到目标机构作者信息的论文很 可能不是目标机构所发表的论文。 关键词 : 论文统计 , 作者甄别 , SCI , 软件设计 Abstract : The software to discriminate one scientific institute's authors of scientific papers is designed to meet demands of the statistics of papers indexed by SCI. It can be used to help the department of statistical analysis on papers in SCI to determine Chinese characters for the Chinese author name belong to their institute and its corresponding lab. Author discrimination is implemented technically by the comprehensive utilization of one characteristics of scientific research that people from the same research units are more likely to co-author papers, custom unique keywords or co-authors and text features of author fields in SCI. Automation and high accuracy of author discrimination can be achieved based on maintenance of a personnel list of one scientific institute. It effectively solves the duplication problem of Chinese names during the analysis of papers in SCI and its design ideas also apply to other databases such as EI and Inspec. Key words : Papers statistics Author discrimination SCI Software design 致谢基金资助: 本文系中国科学院研究所情报分析可持续服务能力建设子项目“中科院高能所情报分析可持续服务能力建设”(项目编号:院1105)和中国科学院国家科学图书馆青年人才领域前沿项目“学科化知识服务辅助工具优化设计”(项目编号:Q1209)的研究成果之一。 致谢 中科院高能所文献信息部于润升主任的选题 鼓励 和 指导 。感谢现代图书情报技术编辑部的多次专业修改建议! 全文pdf下载链接: http://www.infotech.ac.cn/CN/Y2014/V30/I4/78 通讯作者: 于健 E-mail:yuj@mail.las.ac.cn E-mail: yuj@mail.las.ac.cn
发表的期刊论文的列表 Full list of journal papers 5. Predicting Subcellular Localization of Non-Coding RNAs Based Only on Their Sequences Information. (being prepared) 4. An Ensemble Classifier for Predicting the Subcellular Localization of Archaea Proteins. (being prepared) 3. A Novel Multi-Label Ensemble Classifier for Predicting Protein Subnuclear Localization by Incorporating Four Kinds of Features. (being prepared) 2. DNA sequence-dependent physical properties are predictive for identifying 5′/3′ splicing sites. (submitted) 1. PreDNA: accurate prediction of DNA-binding sites in proteins by integrating sequence and geometric structure information.
P. Zhao, J. Zhang, Y. Yuan, J. Dong , S. L., and X. Zhang, "In-line polarization-dependent microfiber interferometers and their applications in UWB signal generation," Opt. Express,in press, 2013 S. Tan, J. Dong , and X. Zhang, "Optical Computation System for Solving Differential Equations Based on Optical Intensity Differentiator," Opt. Express, in press, 2013. J. Dong , A. Zheng, D. Gao, S. Liao, L. Lei, D. Huang, and X. Zhang, "High order photonic differentiator employing on-chip cascaded microring resonators," Optics Letters,vol. 38, pp. 628–630, 2013. J. Dong , A. Zheng, D. Gao, L. Lei, D. Huang, and X. Zhang, "Compact, flexible and versatile photonic differentiator using silicon Mach-Zehnder interferometers," Opt. Express, in press, 2013. J. Dong , A. Zheng, D. Gao, D. Huang, and X. Zhang, "High-order Photonic Differentiator using On-chip Cascaded Mach-Zehnder Interferometers," OFC/NFEOC, Anaheim, CA, USA,OW3D.6, 2013. J. Dong , L. Liu, D. Gao, Y. Yuan, A. Zheng, T. Yang, and X. Zhang, "Compact notch microwave photonic filters using on-chip integrated microring resonators," Photonics Journal, in press, 2013. Y. Zhang, J. Dong, L. Lei, H. He, Y. Yu, and X. Zhang, "Reconfigurable Four-Input Photonic Logic Minterms and Maxterms Generation Using SOAs," Photonics Technology Letters, IEEE, vol. 24, pp. 985-987, 2012. Y. Yu, J. Dong , X. Li, and X. Zhang, "UWB Monocycle Generation and Bi-phase Modulation Based on Mach-Zehnder Modulator and Semiconductor Optical Amplifier," Photonics Journal, vol. 4, pp. 327-339, 2012. B. Luo, T. Yang, J. Dong , Y. Yu, D. Huang, and X. Zhang, "All-Optical Millimeter-Wave Ultrawideband Signal Generation Using a Nonlinear Optical Loop Mirror," Photonics Journal, IEEE, vol. 4, pp. 350-356, 2012. B. Luo, J. Dong , Y. Yu, and X. Zhang, "Bandwidth-tunable single-carrier UWB monocycle generation using a nonlinear optical loop mirror," Photonics Technology Letters, vol. 24, pp. 1646 - 1649, 2012. B. Luo, J. Dong, Y. Yu, T. Yang, and X. Zhang, "Photonic generation of ultra-wideband doublet pulse using a semiconductor-optical-amplifier based polarization-diversified loop," Opt. Lett., vol. 37, pp. 2217-2219, 2012. L. Lei, J. Dong, Y. Yu, S. Tan, and X. Zhang, "All-Optical Canonical Logic Units-Based Programmable Logic Array (CLUs-PLA) Using Semiconductor Optical Amplifiers," Journal of lightwave technology, vol. 30, pp. 3532-3539, 2012.
ASSA ( Advances in Systems Science and Applications ) http://www.ijassa.net:8080/assa/kwjs_en.jsp 欢迎国内在统计物理、复杂系统与复杂性科学、复杂网络、交通流、数据挖掘、信息物理、社会物理、生物物理、经济物理、系统科学及其应用等领域从事研究与教学的各位老师同学踊跃投稿! 稿件可以直接投给编辑部,也可以发给我,由我推荐审稿。 Journal Information Introduction The International Institute for General Systems Studies (IIGSS) was inaugurated in the U.S.A. onJanuary1, 1994.It wasfounded · To promote the fundamental research of general systems theory and applications in all branchesof knowledge, · To establish scientific communications among researchers and practitioners with similar interests inorder toexchange mostrecent ideas and developments in related areas, · To gain international visibility of the advances of the research in general systems theory andapplications and show a unitedcommitment to the arrival of the new era, when all branches of knowledge will be unified under the name of systems, · To provide public relations benefits, · To bring diverse international groups and individuals together as a unified effort to contribute tomultiple endeavors, and · To provide an umbrella for individual members or groups of members of the institute to gain accessofdifferent funding sources, among other things. In the past years, the IIGSS has hosted various workshops, conference, and events. A good numberofrenowned scholarsfrom around the world have been actively involved in IIGSS’ endeavors. Among others, the IIGSS has published an official international journal, entitled Advances in Systems Science and Applications (ASSA). It was originally established as an electronic publication in the 1990s and isnow since the start of the year 2000 a regular hard-copy peer refereed journal. The ASSA aims to reflect the most recent advancement of systems research and welcomes the submission of top qualityresearch papers. Editorial Board ADVANCES IN SYSTEMS SCIENCE AND APPLICATIONS An official journal of the International Institute for General Systems Studies Editor-in-chief: Jeffrey Yi-Lin Forrest President of International Institute for General Systems Studies Department of Mathematics Pennsylvania State System of Higher Education at Slippery Rock Slippery Rock, PA 16057, U.S.A. e-mail: Jeffrey.forrest@sru.edu; Jeffrey.forrest@yahoo.com Associate Editors: Tadeusz Kaczorek Member of Polish Academy of Sciences Faculty of Electrical Engineering, Bia?ystok Technical University ul. Wiejska 45D, 15–351 Bia?ystok, Poland Electrical Engineering, Bialystok University of Technology, Bialystok,. e-mail: kaczorek@isep.pw.edu.pl Kyoich Jim Kijima Graduate School of Decision Science and Technology Tokyo Institute of Technology, 2-12-1 Ookayama , Meguro-ku,Tokyo. 152-8552, Japan e-mail: kijima@valdes.titech.ac.jp Associate Editor/Managing: Dejun Chen School of Information Engineering Wuhan University of Technology Luoshi Road 122, Hongshan District, Wuhan, Hubei 430070 e-mail: mrchendj@163.com Board of Editors: Tsan-Ming (Jason) Choi, Hong Kong Rm ST740, Institute of Textiles and Clothing The Hong Kong Polytechnic University, Hong Kong e-mail: tcjason@inet.polyu.edu.hk Franois Dubois, France President of AFSCET (French Association for Systems Science) since 2008. University Professor at Conservatoire National des Arts et Métiers (Paris). Conservatoire National des Arts et Metiers (CNAM), Mathematiques, 292 rue Saint Martin, 75141 Paris Cedex 03, FranceParis Cedex 03, France e-mail: francois.dubois@cnam.fr Zeraoulia Elhadj, Algeria Department of Mathematics Tébessa University, Tébessa (12002), Algeria. e-mail: zelhadj12@yahoo.fr and zeraoulia@mail.univ-tebessa.dz. Yan Gao, China Executive Dean, Business School University of Shanghai for Science and Technology 516 Jungong Road, Shanghai 200093, PR China e-mail: gaoyan@usst.edu.cn Tseyaye Habtemariam Dean of College of Veterinary Medicine, Nursing Allied Health Tuskegee University, Tuskegee, AL 36088 Phone: 334-727-8174 Fax#: 334-727-8177 e-mail: habtemart@mytu.tuskegee.edu Cheng-Hsiung Hsieh (xie zhengxun), Taiwan Dept Computer Science/Information Engineering Chaoyang University of Technology 168, Jifeng E Rd, Wufeng District Taichung, 41349, Taiwan, ROC e-mail: chhsieh@cyut.edu.tw Jeffrey Johnson, UK (President of Complex Systems Society) The Design Group, Faculty of Maths, Computing and Technology, The Open University, Walton Hall, Milton Keynes, MK7 6AA, UK e-mail: j.h.johnson@open.ac.uk Janusz Kacprzyk, Poland Full Member, Polish Academy of Sciences Systems Research Institute Polish Academy of Sciences ul. Newelska 6, 01-447 Warsaw, Poland e-mail: Janusz.Kacprzyk@ibspan.waw.pl Konstantino Karamanos, Belgium Center for Nonlinear Phenomena and Complex Systems Campus Plaine - CP 231 Université Libre de Bruxelles B-1050 Brussels - Belgium E-mail: kkaraman@ulb.ac.be; koskaraman@gmail.com Qiaoxing Li, China School of Management Lanzhou University Lanzhou, Gansu, PR China e-mail: qxli13@hotmail.com; liqx@lzu.edu.cn Rafael Pla Lopez, Spain Vice-president of the Spanish Society of General Systems Departament de Matemàtica Aplicada, Universitat de València, C/Dr.Moliner, 50, 46100 Burjassot, Spain e-mail: rafael_pla@alteritat.net;Rafael.Pla@uv.es Nicholas A. Nechval, Latvia Department of Applied Mathematics University of Latvia Raina bulv. 19, Riga, LV-1050, Latvia E-mail: nechval@junik.lv Dmitry Novikov, Russia Member of Russian Academy of Sciences PROFSOJUZNAYA ST., 65, Institute of Control Sciences Russian Academy of Sciences MOSCOW, 117997, RUSSIA e-mail: novikov@tushino.com Duc Truong Pham, UK OBE FREng FLSW FSME BE PhD DEng FIET FIMechE Chance Professor and Head of the School of Mechanical Engineering University of Birmingham Edgbaston Birmingham B15 2TT United Kingdom e-mail: http://d.t.pham@bham.ac.uk Jose Perez Rios, Spain E.T.S. Ingenieria Informatica Universidad de Valladolid Campus Miguel Delibes s/n ES-47011 Valladolid, Spain e-mail: rios@uva.es Ganti Prasada Rao Inventive Pathways- Management consultancy PO Box 2623, Abu Dhabi, UAE. e-mail: gant irao@emirates.net.ae Emil Scarlat, Romania Department of Informatics and Economic Cybernetics Bucharest University of Economic Studies 15-17, Calea Dorobantilor, Room 2621 010552, Bucharest , Romania e-mail: emil.scarlat@csie.ase.ro; emil.scarlat@yahoo.com Vladimir Tsurkov, Russia Member of Russian Academy of Sciences Head, Department of Complex Systems of Computing Center Russian Academy of Sciences Vavilov str., 40, Moscow, 119333, Russia e-mail: tsurkov@ccas.ru; tsurkov@gmail.com Edward Tunstel, USA Vice president of IEEE Society of Systems, Man and Cybernetics Applied Physics Laboratory The Johns Hopkins University 11100 Johns Hopkins Road Laurel, Maryland 20723 e-mail: tunstel@gmail.com and tunstel@ieee.org Tom Vaneker, The Netherlands President of European Triz Association Faculty of Engineering Technology University of Twente Drienerlolaan 5, 7522 NB Enschede, The Netherlands e-mail: T.Vaneker@utwente.nl Binghong Wang, China Institute of Theoretical Physics Department of Modern Physics University of Science and Technology of China Hefei, Anhui 230026, P.R.China e-mail: bhwang@ustc.edu.cn; bhwangustc@gmail.com Guo Wei, USA Department of Mathematics and Computer Science University of North Carolina at Pembroke Pembroke, North Carolina, 28372-1510, USA; e-mail: guo.wei@uncp.edu Paul Peng Wen, Australia Deputy Head of Discipline: Electrical and Electronic Engineering Professor, Department of Mathematics and Computing Faculty of Sciences University of Southern Queensland TOOWOOMBA QUEENSLAND 4350 AUSTRALIA e-mail: pengwen@usq.edu.au John Wood, England Emeritus Professor in Design Goldsmiths, University of London, New Cross, London, SE14 6NW, UK e-mail: maxripple@googlemail.com; j.wood@gold.ac.uk Guosheng Zhang, China Associate Dean, School of International Economics and Trade Beijing International Studies University 1 Dingfuzhuang South ST, Chaoqiang distinct Beijing 10024,P.R.China e-mail: zhanggs0804@yahoo.com.cn Key Columns Key columns: ◆ general system theory ◆ system science andengineering ◆ uncertainty system ◆ transportation information and safty ◆ biological engineering ◆ environmental science ◆ image processing ◆ interdisciplinary research Guidelines for Authors Submissions guide Submissions tips contributor tips Advances in Systems Science and Applications(ASSA) aims to promote prompt exchange with worldwide universities and academic institutions. It mainly reflects the latest academic achievements have been and is being made recently in many disciplines ofscientific research in the world. Authors are welcome to submit manuscripts on recent researches that have not beenpublished, nor are intended to be published elsewhere.ASSA owns the copy right of the articles once published in it. The paper relative system science will be received, and following articles are especially welcome : generalsystem theory, system science andengineering, uncertainty system, transportation information and safty, biological engineering, environmental science, image processingand interdisciplinary research. . function resize(img,limitwidth) { if(img.widthlimitwidth) { img.height=img.height*limitwidth/img.width; img.width=limitwidth; } } Submissions statement The manuscript should include the following: title, author's name(s) and biography, company or institute, abstract and key words. The main parts of the manuscript should consist of introduction, materials and methods, results and discussion, conclusion, figures and tables with captions and descriptions, in which detailed quantity, amount and unit will be given. Abstract condenses mainly for the objective, material and methods, key results and conclusion, preferably no less than 300 words in total. Key words should consist of 3-8 words or phrases. All technical measuring units must be in accordance with international standard ( IS). Citation should be listed in accordance with the sequence of quoting at the related part from earlier to later. The format of literatures quoted please refer toASSA already published. Manuscripts should be prepared and submitedin MS Word, however, the editor reserves the right to revise some expressions in the manuscript when it is philologically necessary. Authors who tend not to accept such revision should declare in advance. Contribute notes Notice to contributors Advances in Systems Science and Applications(ASSA) aims to promote prompt exchange with worldwide universities and academic institutions. It mainly reflects the latest academic achievements have been and is being made recently in many disciplines of scientific research in the world. Authors are welcome to submit manuscripts on recent researches that have not been published, nor are intended to be published elsewhere.ASSA owns the copy right of the articles once published in it. The paper relative system science will be received, and following articles are especially welcome : general system theory, system science andengineering, uncertainty system, transportation information and safty, biological engineering, environmental science, image processingand interdisciplinary research. The manuscript should include the following: title, author's name(s) and biography, company or institute, abstract and key words. The main parts of the manuscript should consist of introduction, materials and methods, results and discussion, conclusion, figures and tables with captions and descriptions, in which detailed quantity, amount and unit will be given. Abstract condenses mainly for the objective, material and methods, key results and conclusion, preferably no less than 300 words in total. Key words should consist of 3-8 words or phrases. All technical measuring units must be in accordance with international standard (IS). Citation should be listed in accordance with the sequence of quoting at the related part from earlier to later. The format of literatures quoted please refer toASSA already published . Manuscripts should be prepared and submited in MS Word , however, the editor reserves the right to revise some expressions inthe manuscript when it is philologically necessary. Authors who tend not to accept such revision should declare in advance. . Contact Us Editor-in-chief Jeffrey Yi-Lin Forrest Department of Mathematics Pennsylvania State System of Higher Education Slippery Rock, PA 16057, U.S.A. e-mail: Jeffrey.forrest@sru.edu Associate Editors Tadeusz Kaczorek Electrical Engineering Bialystok University of Technology Bialystok, Poland e-mail: kaczorek@ee.pw.edu.pl Kyoich Kijima Graduate School of Decision Science and Technology Tokyo Institute of Technology 2-12-1 Ookayama , Meguro-ku Tokyo. 152-8552, Japan e-mail: kijima@valdes.titech.ac.jp Associate/Managing Editor Dejun Chen School of Information Engineering Wuhan University of Technology 122 LuoShi Road, Wuhan 430070, China e-mail: mrchendj@163.com Office Online Referee Login Editor-in-chief Login Editor Login Advertisement For Advertiser Ad Query Ad Fast Retrieval ASSA logo
http://www.chemistryviews.org/details/education/2709461/Tips_for_Writing_Better_Science_Papers_Titles_2.html Have you ever struggled to write up your results into a publishable paper only to get it rejected? Richard Threlfall, Managing Editor, Asian Journal of Organic Chemistry , gives some insider tips on how to improve each section of your article and increase your chances of getting published. Titles We're going to start right at the top with the title of your manuscript! The title of a paper is important because it is one of the first things that an editor/reviewer/reader sees when they look at your manuscript. Therefore, it is important to grab their attention right away and give them an idea of why your paper is a scientific breakthrough! Be specific, not too technical, and concise. The other thing to consider is that internet and scientific search tools often search by manuscript title, so if you want to get your paper read and cited, it is important to get some of the key aspects of the research into the title. A good tip is to think which search terms you would use to find your own paper through a web search. For a basic example, consider a (fictional) manuscript entitled "Effect of Metal Catalyst on the Outcome of Reactions with Aryl Alcohols". What is the effect? Which metal? What reaction? What type of aryl alcohols? The editor/reviewer/reader get nothing but questions out of this title! Much better might be: "Ruthenium Trichloride is the Most Efficient Catalyst for C–H Activation with 2,4-Disubstituted Aryl Alcohols". The editor/reviewer/reader immediately knows what the paper is about and will want to read more. Plus, someone who types in terms like "ruthenium", "C–H activation", or "2,4-disubstituted" into a search engine has a much higher chance of finding the second manuscript, but does not get any matches with the title of the first one. Finally, avoid adding every detail from the paper into the title—the title shouldn't be confused with or replace an abstract. The most read and most cited articles often have short and simple titles.
UCREL publishes a series of fully-refereed Technical Papers, under the general editorship of Andrew Wilson and Tony McEnery . These papers fall into two categories: (1) articles dealing with corpora and computational linguistics and (2) corpus manuals. Electronic versions of some of the volumes are available here for free download as PDF format. Simply click on the appropriate PDF icon. Prices refer to hardcopy by post. You can download the free Acrobat Reader from Adobe. Current List of Titles: Database Design for Corpus Storage: The ET10-63 Data Model. Tony McEnery and Beatrice Daille. 1993. 2.50 Corpora and Translation: Uses and Future Prospects. Tony McEnery and Andrew Wilson. 1993. 2.50 Towards an Integration of Content Analysis and Discourse Analysis: The Automatic Linkage of Key Relations in Text. Andrew Wilson. 1993. 2.50 Special Issue. Corpora in Language Education and Research: A Selection of Papers from Talc94 . Edited by Andrew Wilson and Tony McEnery. 10.00 Combined Approach for Terminology Extraction: Lexical Statistics and Linguistic Filtering. Béatrice Daille. 1995. 3.50 'Only Connect'. Critical Discourse Analysis and Corpus Linguistics . Gerlinde Hardt-Mautner. 1995. 2.50 The Evaluation of Multiple Post-Editors: Inter-Rater Consistency in Correcting Automatically Tagged Data. John Paul Baker. 1995. 2.50 Special Issue. Approaches to Discourse Anaphora: Proceedings of the Discourse Anaphora and Resolution Colloquium (DAARC96), edited by Simon Botley, Julia Glass, Tony McEnery and Andrew Wilson. 40.00 . Special Issue. Proceedings of Teaching and Language Corpora 1996. ( TALC96 ) eds. Simon Botley, Julia Glass, Tony McEnery and Andrew Wilson. 280 pages. 1996. ISBN 186220 013 1. 40.00 A Study of Text Typology: Multi-Feature and Multi-Dimensional Analyses. Kaoru Takahashi . 1997. 60 pages. ISBN 1 86220 035 1, 4.50 Special Issue. New Approaches to Discourse Anaphora: Proceedings of the Second Colloquium on Discourse Anaphora and Anaphor Resolution (DAARC2), edited by Simon Botley and Tony McEnery. 1998. 40.00 . Special Issue. Proceedings of the Discourse Anaphora and Reference Resolution Conference (DAARC2000), edited by Paul Baker, Andrew Hardie, Tony McEnery and Anna Siewierska. 2000. 40.00 . Special issue. Proceedings of the Corpus Linguistics 2001 conference, edited by Paul Rayson, Andrew Wilson, Tony McEnery, Andrew Hardie and Shereen Khoja . ISBN 1 86220 107 2. 2001. 40.00 . This is also available as a CDRom (containing PDF versions of the hardcopy) for 6.00 . Special issue. Proceedings of the Workshop on Corpus-Based and Processing Approaches to Figurative Language. Held in conjunction with Corpus Linguistics 2001 edited by John Barnden, Mark Lee and Katja Markert ISBN 1 86220 108 0. 2001. 10.00 The prosody of Please-requests: a corpus based approach. Anne Wichmann 2002. 24 pages. 3.50 Special issue. Proceedings of the Corpus Linguistics 2003 conference, edited by Dawn Archer, Paul Rayson, Andrew Wilson and Tony McEnery . ISBN 1 86220 131 5. 2003. 45.00 . This is also available as a CDRom (containing PDF versions of the hardcopy) for 10.00 . Special issue. Proceedings of the The Workshop on Shallow Processing of Large Corpora (SProLaC 2003) held in conjunction with the Corpus Linguistics 2003 conference, edited by Kiril Simov and Petya Osenova . ISBN 1-86220-134-X 2003. 5.00 . This volume is also available electronically via the organiser's website . The cover and contents page are also included there. Special issue. Proceedings of the Interdisciplinary Workshop on Corpus-Based Approaches to Figurative Language held in conjunction with the Corpus Linguistics 2003 conference, edited by John Barnden, Sheila Glasbey, Mark Lee, Katja Markert and Alan Wallington . ISBN 1-86220-147-1 2003. 5.00 . Printed and bound copies of these Technical Papers can be obtained, at the prices listed (plus postage), from: Technical Papers c/o Paul Rayson Director of UCREL Computing Department Infolab21, South Drive, Lancaster University LANCASTER, LA1 4WA United Kingdom Email: paul at comp.lancs.ac.uk Tel: +44 1524 510357 Fax: +44 1524 510492 Cheques in UK currency should be made payable to "Lancaster University". Some volumes are not out-of-print. We will aim to provide electronic versions instead, if this is suitable. Please contact the same address given above for up-to-date details of titles and availability, or e-mail, in this regard only, to one of the general editors: Andrew Wilson or Tony McEnery . or WATCH THIS SPACE! Abstracts Gerlinde Hardt-Mautner. 'Only Connect'. Critical Discourse Analysis and Corpus Linguistics. 1995.The methodology traditionally used in critical discourse analysis (CDA) is mainly qualitative and hence unwieldy to apply to larger corpora. Standard forms of quantification, on the other hand, involve elaborate classification and coding procedures that destroy the coherence of the original discourse. On the basis of examples from a research project dealing with newspaper language, this paper assesses the potential of concordancing as a research tool for CDA. It is argued that computer-aided analysis enables researchers to blend together qualitative and quantitative views of the data, and to look at a more representative corpus than they can when working manually. John Paul Baker. The Evaluation of Multiple Post-Editors: Inter-Rater Consistency in Correcting Automatically Tagged Data. 1995.The experiment investigated the hypothesis that using human post-editors to check automatically tagged corpora would introduce inconsistencies in the data. Nine experienced post-editors were given sentences of written and spoken data, which had previously been tagged by CLAWS, and asked to remove errors from the output. Once ambivalent words had been removed from the data, mean rater accuracy was found to be higher than the accuracy of CLAWS output (98.7% to 95.3%), while overall consistency between post-editors was 98%. As a result of the experiment, ambivalent cases were resolved through the incorporation of new guidelines. It was also found that if subjects made a slip, it would be highly likely to involve substituting or leaving a noun tag in the place of the correct tag. Kaoru Takahashi. A Study of Text Typology: Multi-Feature and Multi-Dimensional Analyses. 1997.This paper is concerned with text typology. The LOB Corpus, which is a million-word collection of British English texts, is addressed for the study of characterizing text types and identifying linguistic characteristics in each text type. By means of multivariate analysis, the variation of the occurrence of the assigned linguistic features among genre categories yields the classification and systematization of genre categories, and also makes it explicit to specify the characteristics of linguistic features among classified groups. The criteria of the classification are exclusively based on the dimensions which are statistically revealed by the multivariate analysis, and afterwards the groupings are interpreted linguistically. As a result of the analysis, two main dimensions, i.e., ``narrative versus non-narrative concern" and ``specification of content versus generalization of content" enable the classification of three groups among genre categories in the LOB Corpus. As the second stage of this paper, focussing on the tag sequences in the LOB Corpus, the research on text types shifts to the syntactic level. This is carried out by a similar statistical methodology, whereby the syntactic distinction between contrastive linguistic groups, i.e., fiction and exposition is made explicit. Lastly, I touch upon discourse analysis. The linguistic features concerning semantics, e.g., proper nouns, common nouns etc., enable more sophisticated classification of text types macroscopically. This paper concludes with a future plan of research concerning a multi-feature and multi-dimensional approach.
The Lancet, Volume 379, Issue 9818 , Page 787, 3 March 2012 Francis Chan a , Jin Ling Tang a , Sian Griffiths a , Joseph Sung a , Michael R Phillips b c , Helena Wang d Health-care reform in China remains high on the political agenda as moves are made to develop the role of primary care and improve the quality of care. 1 Whilst good progress is being made, 2 large discrepancies still exist between standards of care in rural and urban areas of China. Recognised challenges include the need for investment in community-based care, a shortage of appropriately trained health-care workers, and the promotion of evidence-based prescribing practice and control of prescribing. The Lancet continues to support clinical researchers and health professionals in China, and today publishes its latest issue themed around China's health-care reform and clinical research. The Lancet 's 2013 China themed issue will provide a further opportunity to present some of the outstanding public health and clinical research being carried out in China, and review progress on implementation of the health-care reform programme. The 2013 China issue will be published to coincide with a symposium to be held in Hong Kong in June, 2013 as part of the fiftieth anniversary of the Chinese University of Hong Kong. In addition to advances in clinical practice, major themes including food safety, migration, and the effect of social policies on people's livelihood will be addressed. We invite submissions of high-quality research from China or from research teams working on health in China. Priority will be given to reports of randomised trials that advance the evidence-base of prevention and clinical treatment of disease, and to articles about research on health-system evaluation. Reports on progress in tackling non-communicable diseases, as well as improving care for the elderly, will be welcome. Other studies that have the potential to change clinical and public health practice in China and other countries in the region are also welcome. Please submit manuscripts online before Nov 22, 2012, and mention in your cover letter that the submission is in response to this call for papers. a Chinese University of Hong Kong, Hong Kong, China b Suicide Research and Prevention Centre, Shanghai Mental Health Centre, Shanghai Jiaotong University School of Medicine, Shanghai Jiaotong University, Shanghai, China c Global Health Institute, Emory University, Atlanta, GA, USA d The Lancet, Beijing 100738, China References 1 Liu Q , Wang B , Kong Y , Cheng KK . China's primary health care reform . Lancet 2011 ; 377 : 2064-2066 . Full Text | PDF(531KB) | CrossRef | PubMed 2 Yip WC-M , Hsiao W , Chen W , Hu S , Ma J , Maynard A . Early appraisal of China's huge and complex health-care reforms . Lancet 2012 ; 379 : 833-842 . Summary | Full Text | PDF(162KB) | CrossRef | PubMed
Call for Papers for the International Conference on Virtual Reality and Visualization (ICVRV’12) Qinhuangdao, China, 9/14-9/15, 2012 http://icvrv2012.csp.escience.cn/ About the ICVRV Conference The ICVRV conference, now at its second year, will be hosted by YanShan University, in Qinhuangdao, China from September 14-15, 2012. We are seeking original, high-quality papers in all areas related to virtual reality and visualization, including but not limited to the following topics: · Visualization · 3D interaction for VR · VR systems and toolkits · Modeling and Simulation · User studies and evaluation · Presence and cognition · Augmented and mixed reality · Computer graphics techniques · Tele-presence and Tele-immersion · Applications of AR/MR/VR/Visualization · Haptics, audio, and other non-visual interfaces At the conference the researchers, practitioners and artists from both academia and industry who work in the broad fields of virtual reality and visualization technology will come together to exchange ideas, study development strategy, promote the commercialization of research findings, and work together to boost the development and application of virtual reality and visualization technology. The conference will also invite renowned VR experts to give keynote speeches, hold exhibition for the latest scientific and technology achievements and provide a platform for the researchers as well as companies to show their products. Sponsors: l VR committee of China Society of Image and Graphics l VR and Visualization Committee of China Computer Federation l VR Committee of the China System Simulation Association l IEEE Computer Society ( to be finalized ) Paper Submission: ICVRV categorizes accepted papers in the long (8 pages max) and short (6 pages max) tracks, the difference of the two tracks are mainly contribution size and not the importance/impace of contributions. All submitted papers will be subject to a blind review process by three TPC members. Authors do not need to choose the track at submission time. Papers must be in IEEE conference compliant format and submitted electronically at: https://www.easychair.org/conferences/?conf=icvrv12 The Proceedings will be published by IEEE CPS, and the papers in the proceedings will be indexed by EI. The papers in the proceedings of ICVRV2011 have been indexed by EI. Selected papers will be recommended to journal publications including International Journal of Virtual Reality (English version) and Springer Transaction on Edutainment (EI). General co-chairs: l Tom DeFanti, UCSD, USA l Zhigeng Pan, Hangzhou Normal University, China l Wei Wu, Beihang University, China Technical Program Committee Co-Chairs: l Xun Luo, Qualcomm Inc. l Daniel Thalmann, Nanyang Technological University, Singapore and EPFL, Switzerland l Daniel Acevedo, King Abdullah University of Science and Technology Local Organization Co-Chairs: l Yong Tang, Yanshan University, China l Huagen Wan, Zhejiang University, China Important Dates l Submission Deadline:May 1th,2012 l Notification of acceptance: June 15th, 2012 l Final paper Submission: June 30th, 2012
Description: Special Papers, first published in 1934, were originally developed for articles that were too long to be published in the society’s journal, The Geological Society of America Bulletin. The series has evolved over the years and now includes monographs, symposium-based volumes, and longer, multi-author volumes with dedicated volume editors. Special Papers present state-of-the-art treatments of rapidly evolving subjects, the results of which may be altered or augmented by subsequent research. Many Special Papers have made lasting and significant contributions to the science, and all are vetted by science editors , who choose proposals and completed volumes that are of high quality and broad interest. A wide range of topics is covered from regions throughout the world. GSA's Special Papers have been selected for inclusion in Thomson Reuter's new Book Citation Index. Beginning in November 2011, our book content will begin appearing in the Web of Science. Adapted from http://specialpapers.gsapubs.org/
http://news.sciencenet.cn/htmlnews/2010/12/241357.shtm 生物学领域2010年TOP5文章出炉 据《科学家》网站报道,从合成基因组到砷基生命,今年夺人眼球的研究论文着实不少,但最重要的论文来自对于生命分子基础的研究。近日2010年生物学各领域最重要的5篇论文排名出炉。以下为倒序排名: 5,发现力学信号传导蛋白 论文: Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels 发表期刊及时间:《科学》,1 October 2010 4,血小板在炎性关节炎中的作用 论文: Platelets amplify inflammation in arthritis via collagen-dependent microparticle production 发表期刊及时间:《科学》,29 January 2010 3,呼吸链第一种酶结构确定 论文: The architecture of respiratory complex I 发表期刊及时间:《自然》,27 May 2010 2,纤毛如何交谈 论文: A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution 发表期刊及时间:《科学》,23 July 2010 1, 免疫反应充当病原菌帮凶 论文: Gut inflammation provides a respiratory electron acceptor for Salmonella 发表期刊及时间:《自然》,23 September 2010 更多阅读 《科学家》网站相关报道(英文) http://www.the-scientist.com/news/display/57858/ 3 comments Comment on this news story By Megan Scudellari Top 5 papers of 2010 The most highly ranked articles in all of biology, according to the Faculty of 1000 This was a year of headline science news: the first cell with a synthetic genome, a new human-Neanderthal ancestor and, recently, alien life. Oh, wait...that was just bacteria growing on arsenic. Never mind. iStockphoto.com But, according to scientists, this year's most important papers were not those that made the front page of international newspapers, but the quiet and persistent investigations of the molecular foundations of life. From the long-awaited structure of a bacterial enzyme to how Salmonella grows in the gut, presented here in ascending order are the five most important papers in biology of 2010, as reviewed and ranked by members of the Faculty of 1000. 5. Mechanotransduction proteins found The paper: B. Coste, et al., Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels, Science, 330:55-60, 2010. A new family of proteins, characterized in a mouse cell line, shines new light on the previously mysterious molecular basis of mechanosensation in mammals. Called Piezos, these proteins have been identified as a critical molecular component in mechanically activated ion channels, which make possible several sensations, such as hearing, touch and pain. 4. Inflammation amplification The paper: E. Boilard, et al., Platelets amplify inflammation in arthritis via collagen-dependent microparticle production, Science, 327:580-83, 2010. Researchers identify platelet microparticles -- tiny vesicles that bud from the membranes of activated platelets -- in the fluid of inflamed joints, which rarely contain blood. Importantly, depleting the microparticles using an antibody seemed to cure arthritis in mice. The discovery, published in a January issue of Science, demonstrates the previously unappreciated role of platelets in inflammatory arthritis. Read the full story here. 3. Complex I enzyme revealed The paper: R.G. Efremov, et al., The architecture of respiratory complex I, Nature, 465:441-5, 2010. The long-awaited structure of a bacterial complex I enzyme -- first in line in the energy-producing respiratory chain -- reveals important mechanics of this ubiquitous protein. Specifically, the structure shows how the enzyme hustles electrons and protons across membranes. The structure, published by Nature in May, is one of the largest protein membrane complexes ever solved. 2. How cilia talk The paper: Q. Hu, et al., A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution, Science, 329:436-39, 2010. Primary (nonmotile) cilia -- sensory organelles in eukaryotic cells that act as antennae -- rely on membrane proteins to send and receive extracellular signals. New findings, published in the July issue of Science, show how cilia retain those membrane proteins -- a barrier at the base of cilia made up of proteins called septins. Septins, originally identified as cell division mutants in yeast, localize at the base of the cilium where they maintain a barrier to control the localization of membrane proteins. The discovery solves the long-standing mystery of how signaling proteins are retained in the primary cilium. One of the paper's corresponding authors, Elias Spiliotis, is this month's Scientist to Watch. You can read more about septins, and how they may also help protect yeast from the effects of aging, in our October cover story by Yves Barral. 1. Immune response feeds parasite The paper: S.E. Winter, et al., Gut inflammation provides a respiratory electron acceptor for Salmonella, Nature, 467:426-9, 2010. Salmonella is able to out-compete resident gut microbes by deriving energy from the immune response that is supposed to combat the pathogen, according to a study published in September in Nature. Inflammation in a mouse gut generates a sulfur-based molecule called tetrathionate, which Salmonella uses during respiration for enhanced growth. Read the full news story here. This is a snapshot of the highest ranked biology articles from the previous year on Faculty of 1000, as calculated on December 2, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com. Related stories: Top 7 papers in cell biology Top 7 hidden jewels The five hottest biology papers of 2009 Read more: Top 5 papers of 2010 - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/news/display/57858/#ixzz17f0PUxUQ
http://www.the-scientist.com/news/display/57854/ Top 7 papers in cell biology Just in time for ASCB -- see the cell biology articles most highly ranked by F1000 1. Immune response feeds parasite Color-enhanced scanning electron micrograph showing Salmonella typhimurium (red) invading cultured human cells. Image: Wikimedia commons, NIAID, NIH Salmonella is able to outcompete resident gut microbes by deriving energy from the inflammatory immune response that is supposed to combat the pathogen. S.E. Winter, et al., Gut inflammation provides a respiratory electron acceptor for Salmonella, Nature , 467:426-9, 2010. Evaluated by Matam Vijay-Kumar and Andrew Gewirtz, Emory University; David Alpers, Washington University School of Medicine; Alexei Kurakin and Roya Khosravi-Far, Beth Israel Deaconess Medical Center; Michael Hensel, University of Osnabrck; Yvonne Sun and Mary O'Riordan, University of Michigan Medical School; Wolf-Dietrich Hardt, Swiss Federal Institute of Technology; James Moir, University of York; Victor Nizet, University of California, San Diego. Free F1000 evaluation 2. Piezos for pain A family of proteins, called Piezos, may be components of mechanically activated ion channels which make possible several senses, such as hearing, touch and pain sensation. B. Coste, et al., Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels, Science , 330:55-60, 2010. Evaluated by M. Moran D. Kimball, Hydra Biosciences; J. Garcia-Anoveros, Northwestern University; F. Viana, UMH Instituto de Neurociencias; P. Garrity, Brandeis Univ; B. Nilius, KU Leuven. Free F1000 evaluation 3. New function for noncoding RNAs Long noncoding RNAs, previously known to silence expression of certain genes, also play a role in gene activation. U.A. rom, et al., Long noncoding RNAs with enhancer-like function in human cells, Cell , 143(1):46-58, 2010. Evaluated by L. Ringrose, Inst of Molecular Biotechnology GmbH; A. Clery, Dominik Theler F. Allain, ETH; J. Abrams, U of Texas Southwestern Med Cen at Dallas; H. Steinbeisser, Univ of Heidelberg; E. Lara-Pezzi N. Rosenthal, EMBL. Free F1000 evaluation 4. Proficient pluripotency Researchers created synthetic mRNAs that boost the efficiency of human cell reprogramming, marking a significant advance in induced pluripotent stem (iPS) cell technology. L. Warren, et al., Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA, Cell Stem Cell , 7(5):618-30, 2010. Evaluated by R. Juliano, Univ North Carolina; B. Aranda-Orgilles I. Aifantis, HHMI/NYU School of Med; K. Maass G. Fishman, NYU Langone Med Cen; A. Kriegstein, UCSF. Free F1000 evaluation 5. Details of cell division A complex of proteins crucial for the alignment and separation of chromosomes in dividing cells is directed to the centromeres by the phosphorylating actions of a specific kinase, revealing an important mechanism of cell division that has long escaped scientists. F. Wang, et al., Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis, Science , 2010 Aug 12 doi: 10.1126/science.1189435. Evaluated by W. Earnshaw, Univ of Edinburgh; E. Avvedimento, Univ Federico II; S. Ems-McClung C. Walczak, Indiana Univ; R. Medema, Univ. Med Cen Utrecht, Netherlands; K. Lee, NIH. Free F1000 evaluation 6. Color processing connections Multi-electrode recordings of macaque retinal ganglia allow scientists to map the neural pathways underlying color vision at single-cone resolution, providing insights regarding the functional connectivity of the retinal circuit. G.D. Field, et al., Functional connectivity in the retina at the resolution of photoreceptors, Nature , 467:673-7, 2010. Evaluated by Richard Born, Harvard Medical School; Bruce Cumming, NEI; Christina Joselevitch and David Zenisek, Yale University School of Medicine; David P Wolfer, University of Zurich. Free F1000 evaluation 7. Better nuclei isolation Researchers streamlined a method for tagging nuclei from specific cell types in plants, and purifying them to measure gene expression and chromatin-modification across a variety of tissue types. R.B. Deal and S. Henikoff, A simple method for gene expression and chromatin profiling of individual cell types within a tissue, Dev Cell , 18:1030-40, 2010. Evaluated by E.S. Dennis, CSIRO; E. Lam, Rutgers Univ; D. Chamovitz, Tel Aviv Univ; K. Schneitz, Technische Univ Munchen; P. Kaufman, U Mass Med School. Free F1000 evaluation The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Cell Biology, as calculated on December 3, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com. Related stories: Top 7 immunology papers Top 7 papers in medicine Top 7 genetics papers Read more: Top 7 papers in cell biology - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/news/display/57854/#ixzz17TTy9xiY
http://www.the-scientist.com/news/display/57810/ Top 7 papers in medicine A snapshot of the most highly ranked articles in medicine, from Faculty of 1000 1. To stent or not? A large randomized trial demonstrates that stenting and surgical clearing of arteries are safe and equally effective ways of treating the narrowing of the carotid arteries, called stenosis. T.G. Brott et al., N Engl J Med, 363:11-23, 2010. Evaluated by G. Tang and J. Matsumura, University of Wisconsin; M. Alberts, Northwestern University, M. Nishikawa and T. Milhorat, North Shore University Hospital; P. Pagel C. J. Zablocki, VA Medical Center; P. Newfield, California Pacific Medical Center; B. Norrving, Lund University Hosp; S. Kumar S. Bangalore, Brigham Women's Hospital; Z. Anastasian E. Heyer, Columbia University; N. Hertzer, The Cleveland Clinic. Free F1000 Evaluation 2. Drug helps - not hurts - in serious lung disease Doctors have hesitated to give neuromuscular blocking agents to patients with the life-threatening lung condition called acute respiratory distress syndrome, out of fear the drugs could cause muscle weakness. But a clinical trial found patients who took a neuromuscular blocker were more likely than those on a placebo to survive 90 days, and showed no increase in muscle weakness. (Some faculty members, however, disagreed with the paper's conclusions, arguing narcotics are more appropriate in these patients.) L. Papazian et al, N Engl J Med, 363:1107-16, 2010. Evaluated by M. Gropper, University of California, San Francisco; R. Basner, Columbia University College of Physicians and Surgeons; J. Sellares and A. Torres, Hospital Clinic de Barcelona; M. Gama de Abreu, Clinic Carl Gustav Carus; J. Neely A. Vuylsteke, Papworth Hospital; G. Martin, Emory University; M. O'Connor, University of Chicago; P. Fassbender M. Eikermann, Massachusetts General Hospital. Free F1000 Evaluation 3. Early palliative care helps in advanced cancer Patients with inoperable, metastatic non-small-cell lung cancer may benefit from early palliative care, reporting a better quality of life, and less depression than those who did not receive palliative care. Median survival also improved in those receiving early palliative care, even though they were less likely to receive aggressive treatment at the end of their lives. J.S. Temel et al, N Engl J Med, 363:733-42, 2010. Evaluated by F. Ajaz and R. ZuWallack, St Francis Hospital; D. Spiegel, Stanford University School of Medicine; P. Lee, National University Hospital, Singapore; M. Rodin, St. Louis University Medical School; N. Chao, Duke University Medical Center; H. Klepin, Wake Forest University School of Medicine. Free F1000 Evaluation 4. Key element of bone marrow stem cell niche spotted Researchers have struggled to characterize the cellular components of the hematopoietic stem cell niche in bone marrow, but one has been newly pegged: the other bone marrow stem cell (mesenchymal stem cell), capable of differentiating into cartilage- and bone-forming cells, appears to organize and regulate the stem cell niche in bone marrow, the authors note. S. Mendez-Ferrer, Nature, 466:829-34, 2010. Evaluated by Y. Pang T. Cheng, University of Pittsburgh; N. Bazhanov D. Prockop, Texas AM Health Sciences Center; M. Riminucci P. Bianco, University of Rome La Sapienza; Y. Matsumoto and T. Suda, Keio University. Free F1000 Evaluation 5. Genes behind patchy hair loss A genome-wide association study provides clues to the mysterious pathogenesis of alopecia areata (AA), a common autoimmune disease in which hair falls out in patches, affecting an estimated 2 percent of the population. The paper reveals more than 100 SNPs associated with AA, involved in both innate and adaptive immunity. L. Petukhova et al, Nature, 466:113-7, 2010. Evaluated by S. Inui S. Itami, Osaka University; Y. Ramot A. Zlotogorski, Hadassah-Hebrew University Medical Center; R. Sinclair, University of Melbourne. Free F1000 Evaluation 6. Don't wake me, please The brain doesn't passively transition between consciousness and unconsciousness during anesthesia, based simply on how much of the drug is present, as previously thought, a new study in mice and Drosophila reports. These findings suggest the brain has a tendency to resist such transitions, and may provide insights in sleep regulation and disorders. E.B. Friedman et al, PLoS One, 5(7):e11903, 2010. Evaluated by M. Perouansky, University of Wisconsin; E. Whitlock M. Avidan, Washington University; M. Sahinovic A. Absalom, University Medical Center Groningen. Free F1000 Evaluation 7. Pain relief for the addicted In patients with a dependence on opiates, pain relief is tough to achieve, but those who received ketamine, an N-methyl-d-aspartate receptor antagonist, with anesthesia during back surgery reported less pain and needed less morphine during recovery. R.W. Loftus, et al, Anesthesiology, 113:639-46, 2010. Evaluated by C. Rivat P. Richebe, University of Washington; L. Le-Wendling A. Boezaart, University of Florida College of Medicine; A. Barreveld D. Correll, Brigham Women's Hospital; A. Lynn, Children's Hospital, Seattle; D. Gupta, Feinberg School of Medicine Northwestern University. Free F1000 Evaluation The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Medicine, as calculated on November 11, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com. Related stories: Top 7 hidden jewels Top 7 papers in biochemistry Top 7 papers in neuroscience Read more: Top 7 papers in medicine - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/news/display/57810/#ixzz15TALmWLn
Call for Papers Workshop Proposals Eighth International Conference on Complex Systems (ICCS 2011) Host: New England Complex Systems Institute June 26 - July 1, 2011 Boston Marriott Quincy, MA, USA Click here to register This is the eighth in a series of conferences with two major aims: first, to investigate those properties or characteristics that appear to be common to the very different complex systems now under study; and second, to encourage cross fertilization among the many disciplines involved. ICCS TOPICS: UNIFYING THEMES IN COMPLEX SYSTEMS Sessions will be structured around both themes and systems. The themes are: Emergence The relationship of component to collective behavior; the relationship of internal structure to external influence; multiscale structure and dynamics; self-similarity and fractals. Complexity Information Defining complexity; characterizing the information necessary to describe complex systems; structuring, storing, accessing, distributing, visualizing and analyzing information describing complex systems; the dynamics of information and its computational characterization. Dynamics Self-Organization Time series analysis and prediction; chaos; temporal correlations; the time scale of dynamic processes; spatio-temporal patterns; dynamic scaling; pattern formation; evolution, development and adaptation; interaction between internal dynamics and external inputs; programmability of self-organization. Networks Complex network topologies; small-world and scale-free networks; connectivity and centrality; motifs, cliques and communities; dynamical networks; adaptive networks; network modeling and analysis; modularity, degeneracy, redundancy, and substructure; visualization of networks. Methodology Computer simulation; agent-based modeling; data-driven research methods; analytical methods; nonlinear statistics; soft computing; methods and tools for complex systems education. The system categories are: Physical Chemical Systems Non-equilibrium processes; hydrodynamics; glasses; non-linear chemical dynamics; complex fluids; molecular self-organization; information and computation in quantum and classical physical systems; spatio-temporal patterns in physical systems from subatomic to astrophysical. Bio-Molecular Cellular Systems Systems biology; protein and DNA folding; bio-molecular informatics; membranes; cellular response and communication; genetic regulation; gene cytoplasm interactions; development; cellular differentiation; primitive multicellular organisms; the immune system; origins of life. Physiological Psychological Systems Nervous system; sensorimotor systems; computational models of neural and cognitive function; perception, cognition and action; psychological dysfunction; pattern recognition; learning and development; human machine interaction; autonomous mental development; neurocognitive networks. Organisms Populations Population biology; ecosystems; ecology; ecological networks; speciation; evolution. Human Social Economic Systems Social networks; corporate and social structures and dynamics; organizational behavior and management; markets; urban development; the global economy; military systems; global conflict; interactions between human and natural systems. Engineered Systems Design and manufacturing; nano-technology; bioengineering; modified and hybrid biological organisms; computer based interactive systems; multi-agent systems; artificial life; artificial intelligence; robots; communication networks; the Internet; traffic systems; distributed control; self organizing artifacts; complex systems engineering; biologically inspired engineering; sensor networks. ABSTRACT SUBMISSION AND PROCEEDINGS PUBLICATION: For presentation at the conference, authors should submit an abstract through the conference website. All the accepted abstracts will be published in the online proceedings on the conference website. Authors of accepted abstracts may submit full papers for inclusion in the online proceedings. Full paper submission is optional. Note to Authors If you plan to submit an abstract/paper to the conference, please follow the link on the conference website to the pre-submission page AS SOON AS POSSIBLE. You can update your submission's title, abstract, authors and paper at any time until the submission deadline. This pre-submission process will help the organizers estimate the number of incoming submissions and develop the conference program and other logistics efficiently. WORKSHOPS There will be several time slots available during the conference for organizing workshops on specific topics. All the accepted abstracts/papers for the workshop will be included in the conference proceedings as well. If you are interested in organizing a workshop, email the following information to sayama@binghamton.edu by December 20, 2010: Name(s) and contact information of the workshop organizer(s) Title of the workshop A short description of the workshop: (aim, scope, target audience, format and expected outcome) A list of confirmed and prospective speakers IMPORTANT DATES AND DEADLINES Workshop proposal: December 20, 2010 Abstract submission: February 28, 2011 Notification to authors: April 1, 2011 Early registration: April 15, 2011 Camera-ready abstract full paper submission: (full paper submission is optional) April 30, 2011 Conference: June 26 - July 1, 2011 Register at http://necsi.edu/events/iccs2011/ Space is limited, so register early. LOCATION AND ACCOMMODATIONS The conference will be held at the Boston Marriott Quincy in Quincy, Massachusetts, 8 miles south of downtown Boston. Reservations can be made directly with Marriott reservations at (866) 449-7387 or (617) 472-1000, or online at: www.quincymarriott.com . A block of rooms has been reserved at a conference discount rate of $159 + tax per night (single or double). Internet access is included. These rooms are available on a first-come, first-served basis. To receive the discount rate identify yourself as a member of ICCS 2011. The group code for making reservations online is NECNECA. These rates are available until Friday, May 27, 2011. Cancellations may be made up to 48 hours in advance without penalty. ORGANIZATION Executive Committee Founding Chair: Yaneer Bar-Yam (New England Complex Systems Institute, USA) General Chair: Ali A. Minai (University of Cincinnati, USA) General Co-Chair: Dan Braha (University of Massachusetts at Dartmouth, USA) Program Chair: Hiroki Sayama (Binghamton University, SUNY, USA) Program Committee Albert-Lszl Barabsi (Northeastern University, USA) Ginestra Bianconi (Nothestern University, USA) Philippe Binder (University of Hawaii, USA) Eric Bonabeau (Icosystem Corporation, USA) Josh Bongard (University of Vermont, USA) Seth Bullock (University of Southampton, UK) Guido Caldarelli (INFM, Rome, Italy) Iain Couzin (Princeton University, USA) Marcus de Aguiar (IFGW - UNICAMP, Brazil) Fred Discenzo (Rockwell Automation, USA) Ren Doursat (Complex Systems Institute, Paris, France) Margaret J. Eppstein (University of Vermont, USA) Carlos Gershenson (Univ. Nacional Autonoma de Mexico, Mexico) Robert Ghanea (British Telecom, UK) Thilo Gross (Max Planck Institute for the Physics of Complex Systems, Germany) Helen Harte (Community Health Plan, USA) Alfred Hubler (University of Illinois at Urbana-Champaign, USA) Mark Klein (Massachusetts Institute of Technology, USA) Juergen Kluever (University of Duisburg Essen, Germany) May Lim (University of the Philippines, Philippines) Czeslaw Mesjasz (Karakow University of Economics, Poland) Lilianne R Mujica-Parodi (Stony Brook University, SUNY, USA) Chrystopher Nehaniv (University of Hertfordshire, UK) Lael Parrott (Universit de Montral, Canada) Daniel Polani (University of Hertfordshire, UK) Christina Stoica (University of Duisburg Essen, Germany) Bill Sulis (McMaster University, Canada) Irina Trofimova (McMaster University, Canada) Len Troncale (California State University Pomona, USA) Jonathan Vos Post (Computer Futures, USA) Richard Watson (University of Southampton, UK) Janet Wiles (University of Queensland, Australia) Ian Wilkinson (University of New South Wales, Australia) David Wolpert (NASA Ames Research Center, USA) More PC members TBA FOR MORE INFORMATION Check the conference website: http://necsi.edu/events/iccs2011/ Contact us at iccs@necsi.edu cx-web@necsi.org
http://www.the-scientist.com/news/display/57800/ Top 7 papers in neuroscience A snapshot of the highest-ranked articles in neuroscience and related fields, as ranked by F1000 1. Mechanotransduction proteins found A family of proteins, called Piezos, has been identified as important players in mechanically activated ion channels, which make possible several senses, such as hearing, touch and pain sensation. B. Coste, et al., Science, 330:55-60, 2010. Evaluations by M. Moran and D. Kimball, Hydra Biosciences; J. Garcia-Anoveros, Northwestern University; F. Viana, UMH Instituto de Neurociencias; P. Garrity, Brandeis Univ; B. Nilius, KU Leuven. Free F1000 Evaluation 2. Epigenetics in mind Mouse litter Seweryn Olkowicz The body's tendency to silence the expression of one parental allele in favor of the other -- a practice known as genomic imprinting -- is much more widespread in the brain than scientists have believed, according to a new genome-wide study in mice. Surprisingly, more than 1300 genes in the mouse brain appear to exhibit parent-of-origin epigenetic effects. C. Gregg, et al., Science, 329:643-8, 2010. Evaluations by R. Sapolsky, Stanford University; M.E. Carter and L. de Lecea, Stanford Univ; J. Messing, Rutgers University; Y. Ikeuchi and A. Bonni, Harvard Medical School; D. Sweatt, University of Alabama at Birmingham. Free F1000 Evaluation 3. Translation goes local Protein synthesis is a complicated game, but for the first time researchers have shown direct interaction between a transmembrane receptor, called DCC, with translational machinery in neurons, a step that likely facilitates localized protein manufacture. J. Tcherkezian, et al., Cell, 141:632-44, 2010. Evaluations by R. Darnell, Rockefeller Univ; K. Kwan and C.B. Chien, Univ Utah; J. Heraud and M. Kiebler, Ctr for Brain Res, Med Univ Vienna, Austria; W. Kroeze and B. Roth, Univ North Carolina; L. Desgroseillers, Univ Montreal, Canada; L. Columbus, Univ Virginia. Free F1000 Evaluation 4. What makes neurons dependent Neurons in the peripheral nervous system need specific secretory molecules to survive during development while neurons in the central nervous system do not, and researchers now know why. Neurons in the PNS express two neurotrophin receptors, TrkA and TrkC, that induce cell death in absence of their ligands, while neurons in the CNS express receptor TrkB, which does not. V. Nikoletopoulou, et al., Nature, 467:59-63, 2010. Evaluations by A.M. Davies, Cardiff University; M. Bothwell, University of Washington; H. Nakamura, Tohoku University, Japan. Free F1000 Evaluation 5. How the cortex interprets context New findings illustrate the physiological underpinnings of animals' ability to change their response to external stimulus depending on the context of the situation. The firing activity of neurons in the brain is context-dependent -- when monkeys are confronted with identical visual stimuli, their neuronal activity varies depending on which of two different perceptual tasks they perform. M.R. Cohen, et al., Neuron, 60:162-73, 2010. Evaluations by M. Carandini, University College London; B. Cumming, NEI; D. Angelaki, Washington University School of Medicine. Free F1000 Evaluation 6. Fusion in a snap Fewer SNARE complexes -- bundles of SNAP receptors that mediate vesicle fusion -- are required for vesicle-membrane fusion during exocytosis than previously believed. Past estimates ranged up to eleven SNARES, but fast fusion requires as few as three and slow fusion may need as few as one, according to new evidence. R. Mohrmann, et al., Science, 330:502-5, 2010. Evaluations by L. Tamm, University of Virginia; Y. Xu and D. Tommre, Yale University School of Medicine; D. Stevens and J. Rettig, Universitaet des Saarlandes. Free F1000 Evaluation 7. The value of diversity Neuronal diversity -- variability in the electrophysiological properties of neurons -- is not just chance imprecision but a valuable feature of the nervous system. Diverse populations of neurons in the mouse olfactory bulb code more information than their homogeneous counterparts, researchers find. K. Padmanabhan, et al., Nat Neurosci, 13:1276-82, 2010. Evaluations by B. Brembs, Freie Universitat Berlin; R. Wilson, Harvard Medical School. Free F1000 Evaluation The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Neuroscience, as calculated on November 8, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com/. Related stories: Top 7 genetics papers Top 7 hidden jewels Read more: Top 7 papers in neuroscience - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/news/display/57800/#ixzz14pmpMIg4
http://www.the-scientist.com/news/display/57794/ A snapshot of the highest-ranked articles in genetics and related areas in the past 30 days 1. Mapping transcriptomes While mapping every transcriptional start site and operon of Helicobacter pylori at single-nucleotide resolution, the authors identify novel small RNAs, reveal the widespread nature of antisense transcription, and unveil a new technique to investigate the genomic complexities of other important pathogens, such as Salmonella and Mycobacterium tuberculosis. CM Sharma et al, Nature, 464:250-5, 2010. Evaluated by N. Ahmed, Institute of Life Sciences, India; M. Hensel, Friedrich-Alexander University Erlangen-Nuremberg (FAU); S. Ho Sui and F. Brinkman, Simon Fraser University; S. Vogt and T. Raivio, University of Alberta; A. Danielli and V. Scarlato, University of Bologna. Free F1000 Evaluation DNA Image: Wikimedia commons, Zephyris 2. Epigenetics in mind The body's tendency to silence the expression of one parental allele in favor of the other -- a phenomenon known as genomic imprinting -- is much more widespread in the brain than scientists have believed, according to a new genome-wide study in mice. Surprisingly, more than 1300 genes expressed in the mouse brain appear to exhibit parent-of-origin epigenetic effects. C. Gregg, et al., Science, 329:643-8, 2010. Evaluations by R. Sapolsky, Stanford University; ME Carter and L. de Lecea, Stanford University; J. Messing, Rutgers University; Y Ikeuchi and A Bonni, Harvard Medical School; D Sweatt, University of Alabama at Birmingham. Free F1000 Evaluation 3. Translation goes local Protein synthesis is a complicated game, but for the first time researchers have shown direct interaction between a transmembrane receptor, called DCC, and the translational machinery in rodent neurons, a step that likely facilitates localized protein production. J. Tcherkezian, et al., Cell, 141:632-44, 2010. Evaluations by K Kwan and CB Chien, University of Utah; J Heraud and M Kiebler, Center for Brain Research, Medical University of Vienna, Austria; W Kroeze and B Roth, University of North Carolina; L Desgroseillers, University of Montreal, Canada; L Columbus, University of Virginia. Free F1000 Evaluation 4. No RNA dark matter? Most of the DNA that's transcribed into RNA in fact codes for proteins, a finding that disputes previous studies that suggested that the majority of mammalian transcripts are non-coding dark matter. H. van Bakel et al. PLoS Biol, May; 8(5):e1000371, 2010. A Siepel, Cornell University; S Macdonald, University of Kansas; A Sellam and A Nantel, National Research Council of Canada; D Reines, Emory University School of Medicine. Free F1000 Evaluation 5. Super E. Coli The mother cell of E. coli maintains a constant growth rate throughout its replicative life (hundreds of cell divisions), despite accumulating damage and an increased probability of death, suggesting that growth and aging are decoupled, unlike all other studied aging models. P. Wang et al., Curr Biol, 2010 May 26, 20:1099?1103. Evaluated by R Kishony, Harvard University; T Meier, Max Planck Inst Biophysics; Yves Barral, ETH. Free F1000 Evaluation 6. How autophagosomes form Under conditions of starvation, autophagosomes form to resupply the cell by bringing nutrients from the cytosol or other organelles to the lysosomes, ensuring the cell's survival. New findings reveal an essential ingredient to this mysterious process: the outer membrane of mitochondria. DW Hailey et al. Cell, 141:656-67, 2010. Evaluated by R Gross, University of Wuerzburg, Germany; M Markaki and N Tavernarakis, Foundation for Research and Technology-Hellas, Greece; Y Xiang and Y Wang, University of Michigan, E Lau and Z Ronai, The Burnham Institute. Free F1000 evaluation 7. New tumor targets? A scan of 1800 megabases of DNA from 441 tumors reveals more than 2500 somatic mutations, providing the mutation spectra for cancers, including protein kinases and G-protein-coupled receptors, some of which may serve as druggable targets. Z. Kan et al, Nature, 466:869-73, 2010. Evaluated by T Ried, National Cancer Institute; D Nierlich, University of California, Los Angeles; S Gutkind, National Institute of Dental and Craniofacial Research. Free F1000 evaluation The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Genomics Genetics, as calculated on October 28, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com. Related stories: Top 7 hidden jewels Top 7 papers in biochemistry Top 7 papers in neuroscience Read more: Top 7 genetics papers - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/news/display/57794/#ixzz14AgI6xh0
http://www.the-scientist.com/article/display/57722/ Volume 24 | Issue 10 | Page 26 Date: 2010-01-10 Reprints | Issue Contents var addthis_config = { services_exclude: 'print,printfriendly', services_custom: { name: "Print", url: "http://www.the-scientist.com/article/print/57600", icon: "http://images.the-scientist.com/graphics/interface/print.gif"} }; Comment on this article Top 7 From F1000 1. How fat causes diabetes There are new molecular links between obesity and diabetesa high-fat diet in mice activates proteins associated with obesity, but these changes can be reversed by a well-known diabetes drug, suggesting the same pathway may also cause insulin-resistance. J.H. Choi et al., Nature , 466:451-56, 2010. Evaluated by L. Hamann, Novartis; M. Andresen, OHSU; P. Webb, TMHRI. Free F1000 Evaluation Related Articles Waterbirds: A Slideshow Bird Sex Gene Found Splitting Two Birds with One Gene 2. A new metabolism A novel metabolic pathway in the malaria parasite differs significantly from the classic Krebs cycle taught in textbooks, providing evidence that carbon metabolism can evolve. K.L. Olszewski et al., Nature , 466:774-78, 2010. Evaluated by P. Roepe, Georgetown; R. Abraham, Pfizer. Free F1000 Evaluation 3. Double-edged gene Two gene variants found commonly in African genomes, which appear to explain why African Americans have higher rates of kidney disease than European Americans, may have been selected for because they confer resistance to a parasite that causes African sleeping sickness. G. Genovese et al., Science , 329:841-45, 2010. Evaluated by W. Gibson, Univ Bristol; M. Breyer, Lilly Res Lab; C. Clayton, Univ Heidelberg; M. Parsons, Seattle Biomed. Free F1000 Evaluation 4. Focal structure For the first time, researchers have described the three-dimensional molecular structure of focal adhesions, providing insights into how they secure cells to the extracellular matrix and participate in mechanosensory events. I. Patla et al., Nat Cell Biol , 12:909-15, 2010. Evaluated by R. Zaidel-Bar, Nat Univ Singapore; M. Himmel and S. Linder, UKE. Free F1000 Evaluation 5. How neurons grow Theres another layer of complexity in the developing nervous system: Spontaneous neuronal activity can regulate the differentiation of neurons, affecting swimming behavior in frog larvae. M. Demarque et al., Neuron , 67:321-34, 2010. Evaluated by K. Sillar, Univ St Andrews; J.S. Eisen, Univ Oregon; A. Mar?n-Burgin and A. Schinder, Leloir Inst. Free F1000 Evaluation 6. Retinal roles Photosensitive ganglion cells, which were only discovered in the mammalian retina in the early 1990s, play a greater role in visual function than previously believed. J.L. Ecker, Neuron , 67:49-60, 2010. Evaluated by R. Hardie, Univ Cambridge; S. Reppert, UMass Med. Free F1000 Evaluation 7. How cilia talk Primary (nonmotile) cilia need membrane proteins to send and receive extracellular signals as part of their role as a coordinator of signaling pathways, and new findings show how cilia retain those membrane proteinsa barrier at the base of cilia made up of proteins called septins. Q. Hu et al., Science , 329:436-39, 2010. Evaluated by Y. Barral, ETH; M. Wirschell and W. Sale, Emory; H. Folsch, Northwestern; Y. Yamashita, UMich; M. Bettencourt-Dias, IGC; S. Feng and W. Guo, UPenn; M. Labouesse, CNRS; J. Axelrod, Stanford. Free F1000 Evaluation The F1000 Top 7 is a snapshot of the highest-ranked articles from a 30-day period on Faculty of 1000 Biology. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com/ . Read more: Top 7 From F1000 - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/article/display/57722/#ixzz13narYQ3m
http://www.the-scientist.com/news/display/57753/ Comment on this news story By Cristina Luiggi Top 7 papers in biochemistry Check out the highest F1000-ranked articles in biochemistry and related areas 1. How cilia talk Primary (nonmotile) cilia need membrane proteins to send and receive extracellular signals as part of their role as a coordinator of signaling pathways, and new findings show how cilia retain those membrane proteins -- a barrier at the base of cilia made up of proteins called septins. Materialscientist Wikimedia Commons Q. Hu et al., Science , 329:436-39, 2010. Evaluated by Y. Barral, ETH; M. Wirschell and W. Sale, Emory; H. Folsch, Northwestern; Y. Yamashita, UMich; M. Bettencourt-Dias, IGC; S. Feng and W. Guo, UPenn; M. Labouesse, CNRS; J. Axelrod, Stanford. Free F1000 Evaluation 2. Nickel allergy explained Allergy to nickel plated jewelry is initiated because Toll-like receptor 4 (TLR4) binds and recognizes nickel in much the same way that it recognizes lipopolysaccharides, a component of the bacterial cell wall. M. Schmidt et al., Nat Immunol , 11:814-9, 2010. Evaluated by Marc Rothenberg, Cincinnati Children's Hosp Med Center; Caetano Reis e Sousa, Cancer Research UK; Michael Maroney, Univ of Massachusetts. Free F1000 Evaluation 3. Third one's the charm By comparing the three conformations in the crystal structure of a key microbacterial transporter protein, researchers propose a model for how the protein -- similar to those involved in mammalian neurotransmission -- moves substrates across the membrane. T. Shimamura, et al., Science, 328:470-3, 2010. Evaluations by Louis De Felice, Virginia Commonwealth Univ; Baruch Kanner, Hebrew Univ Hadassah Medical School, Israel; Robert Vandenberg, Univ of Sydney, Australia; Gary Rudnick, Yale Univ School of Medicine. Free F1000 Evaluation 4. Source of mechanotransduction? Researchers pinpoint the molecular identity of a mechanosensitive channel in C. elegans, suggesting a possible starting point for the hunt for mechanotransduction channels mediating hearing, touch, and propioception in mammals. L. Kang, et al., Neuron, 67:381-91, 2010. Evaluations by Rachel Wilson, Harvard Medical School; Andy Groves, Baylor College of Medicine; Paul Garrity, Brandeis Univ; Roger Hardie, Univ of Cambridge. Free F1000 Evaluation 5. Shining new light on fMRI A new approach strengthens the technical validity of functional Magnetic Resonance Imaging (fMRI) -- which measures changes in blood oxygen levels in the brain as a proxy for neuronal activity -- by combining it with a system that activates specific types of neurons using pulses of light. J.H. Lee, et al., Nature , 465:788-92, 2010. Evaluations by Aina Puce, Indiana Univ.; Atsushi Iriki, RIKEN Brain Science Institute; Luis de Lecea, Stanford Univ. Free F1000 Evaluation 6. The many mutations of cancer Lung carcinoma Wikimedia Commons A comprehensive analysis of 441 tumor samples of human breast, lung, ovarian, and prostate cancers revealed strikingly diverse mutational backgrounds among cancer types and subtypes while identifying potential novel drug targets. Z. Kan, et al., Nature , 466:869-73, 2010. Evaluations by Thomas Ried, National Cancer Institute; Donald Nierlich, UCLA; Silvio Gutkind, National Institute of Dental and Craniofacial Research. Free F1000 Evaluation 7. Guidance proteins in action Researchers have finally described the detailed crystal structure of signaling proteins, called semaphorins, interacting with their receptors (plexins), affording insights that may help target drugs to ailing nervous, cardiovascular or immune systems, where the binding partners regulate development and functioning. H. Liu, et al., Cell , 142:749-61, 2010. Evaluations by Yuxiao Wang and Xuewu Zhang, Univ of Tex Southwestern Med Ctr; Prasanta Hota and Matthias Buck, Case Western Res Univ; Guido Serini and Giulio Gabbiani, Univ Geneva. Free F1000 Evaluation The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Biochemistry, as calculated on October 14, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com/. Related stories: Top 7 papers in neuroscience Top 7 in developmental biology Top 7 immunology papers Read more: Top 7 papers in biochemistry - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/news/display/57753/#ixzz1346I2A7N
Emergent Nature Inspired Algorithms for Multi-Objective Optimization Guest Edited by Jos Rui Figueira and El-Ghazali Talbi Submission Deadline: November 2010 Multiple criteria Decision Making in Emergency Management Guest Edited by Yi Peng and Lean Yu Submission Deadline: 31 December 2010 Operations Research for health care delivery Guest Edited by Angela Testi, Elena Tanfani and Roberto Aringhieri Submission Deadline: December 2010 Grasp and Path Relinking Guest Edited by Mauricio G. C. Resende, Celso C. Ribeiro and Rafael Mart Submission Deadline: 31 January 2011 Hierarchical Optimization and its Application in Engineering Guest edited by Georgios K.D. Saharidis, Antonio J. Conejo and Steven Gabriel Submissions Accepted After: 1 January 2011 Submission Deadline: 31 December 2011
http://www.the-scientist.com/news/display/57753/ Top 7 papers in biochemistry Check out the highest F1000-ranked articles in biochemistry and related areas 1. How cilia talk Primary (nonmotile) cilia need membrane proteins to send and receive extracellular signals as part of their role as a coordinator of signaling pathways, and new findings show how cilia retain those membrane proteins -- a barrier at the base of cilia made up of proteins called septins. Materialscientist Wikimedia Commons Q. Hu et al., Science , 329:436-39, 2010. Evaluated by Y. Barral, ETH; M. Wirschell and W. Sale, Emory; H. Folsch, Northwestern; Y. Yamashita, UMich; M. Bettencourt-Dias, IGC; S. Feng and W. Guo, UPenn; M. Labouesse, CNRS; J. Axelrod, Stanford. Free F1000 Evaluation 2. Nickel allergy explained Allergy to nickel plated jewelry is initiated because Toll-like receptor 4 (TLR4) binds and recognizes nickel in much the same way that it recognizes lipopolysaccharides, a component of the bacterial cell wall. M. Schmidt et al., Nat Immunol , 11:814-9, 2010. Evaluated by Marc Rothenberg, Cincinnati Children's Hosp Med Center; Caetano Reis e Sousa, Cancer Research UK; Michael Maroney, Univ of Massachusetts. Free F1000 Evaluation 3. Third one's the charm By comparing the three conformations in the crystal structure of a key microbacterial transporter protein, researchers propose a model for how the protein -- similar to those involved in mammalian neurotransmission -- moves substrates across the membrane. T. Shimamura, et al., Science, 328:470-3, 2010. Evaluations by Louis De Felice, Virginia Commonwealth Univ; Baruch Kanner, Hebrew Univ Hadassah Medical School, Israel; Robert Vandenberg, Univ of Sydney, Australia; Gary Rudnick, Yale Univ School of Medicine. Free F1000 Evaluation 4. Source of mechanotransduction? Researchers pinpoint the molecular identity of a mechanosensitive channel in C. elegans, suggesting a possible starting point for the hunt for mechanotransduction channels mediating hearing, touch, and propioception in mammals. L. Kang, et al., Neuron, 67:381-91, 2010. Evaluations by Rachel Wilson, Harvard Medical School; Andy Groves, Baylor College of Medicine; Paul Garrity, Brandeis Univ; Roger Hardie, Univ of Cambridge. Free F1000 Evaluation 5. Shining new light on fMRI A new approach strengthens the technical validity of functional Magnetic Resonance Imaging (fMRI) -- which measures changes in blood oxygen levels in the brain as a proxy for neuronal activity -- by combining it with a system that activates specific types of neurons using pulses of light. J.H. Lee, et al., Nature , 465:788-92, 2010. Evaluations by Aina Puce, Indiana Univ.; Atsushi Iriki, RIKEN Brain Science Institute; Luis de Lecea, Stanford Univ. Free F1000 Evaluation 6. The many mutations of cancer Lung carcinoma Wikimedia Commons A comprehensive analysis of 441 tumor samples of human breast, lung, ovarian, and prostate cancers revealed strikingly diverse mutational backgrounds among cancer types and subtypes while identifying potential novel drug targets. Z. Kan, et al., Nature , 466:869-73, 2010. Evaluations by Thomas Ried, National Cancer Institute; Donald Nierlich, UCLA; Silvio Gutkind, National Institute of Dental and Craniofacial Research. Free F1000 Evaluation 7. Guidance proteins in action Researchers have finally described the detailed crystal structure of signaling proteins, called semaphorins, interacting with their receptors (plexins), affording insights that may help target drugs to ailing nervous, cardiovascular or immune systems, where the binding partners regulate development and functioning. H. Liu, et al., Cell , 142:749-61, 2010. Evaluations by Yuxiao Wang and Xuewu Zhang, Univ of Tex Southwestern Med Ctr; Prasanta Hota and Matthias Buck, Case Western Res Univ; Guido Serini and Giulio Gabbiani, Univ Geneva. Free F1000 Evaluation The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Biochemistry, as calculated on October 14, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com/. Related stories: Top 7 papers in neuroscience Top 7 in developmental biology Top 7 immunology papers Read more: Top 7 papers in biochemistry - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/news/display/57753/#ixzz12vlKkEZ1
http://www.the-scientist.com/news/display/57742/ Top 7 papers in neuroscience A snapshot of the highest-F1000-ranked articles in neuroscience and related areas 1. Epigenetics in mind The body's tendency to silence the expression of one parental allele in favor of the other -- a practice known as genomic imprinting -- is much more widespread in the brain than scientists have believed, according to a new genome-wide study in mice. Surprisingly, more than 1300 genes in the mouse brain appear to exhibit parent-of-origin epigenetic effects. Kessa Ligerro Wikimedia Commons C. Gregg, et al., Science, 329:643-8, 2010. Evaluations by Matt E. Carter and Luis de Lecea, Stanford Univ; Joachim Messing, Rutgers Univ; Yoshiho Ikeuchi and Azad Bonni, Harvard Medical School; David Sweatt, University of Alabama at Birmingham. Free F1000 Evaluation 2. Mechanotransduction proteins found A family of proteins, called Piezos, has been identified as important players in mechanically activated ion channels, which make possible several senses, such hearing, touch and pain sensation. B. Coste, et al., Science, 330:55-60, 2010. Evaluations by Felix Viana, UMH Instituto de Neurociencias; Paul Garrity, Brandeis Univ; Bernd Nilius, KU Leuven. Free F1000 Evaluation 3. Translation goes local Protein synthesis is a complicated game, but for the first time researchers have shown direct interaction between a transmembrane receptor, called DCC, with translational machinery in neurons, a step that likely facilitates localized protein manufacture. J. Tcherkezian, et al., Cell, 141:632-44, 2010. Evaluations by Kristen Kwan and Chi-Bin Chien, Univ Utah; Jacki Heraud and Michael Kiebler, Ctr for Brain Res, Med Univ Vienna, Austria; Wes Kroeze and Bryan Roth, Univ North Carolina; Luc Desgroseillers, Univ Montreal, Canada; Linda Columbus, Univ Virginia. Free F1000 Evaluation 4. Third one's the charm By comparing the three conformations in the crystal structure of a key microbacterial transporter protein, researchers propose a model for how the protein -- similar to those involved in mammalian neurotransmission -- moves substrates across the membrane. T. Shimamura, et al., Science, 328:470-3, 2010. Evaluations by Louis De Felice, Virginia Commonwealth Univ; Baruch Kanner, Hebrew Univ Hadassah Medical School, Israel; Robert Vandenberg, Univ of Sydney, Australia; Gary Rudnick, Yale Univ School of Medicine. Free F1000 Evaluation 5. Source of mechanotransduction? Researchers pinpoint the molecular identity of a mechanosensitive channel in C. elegans, suggesting a possible starting point for the hunt for mechanotransduction channels mediating hearing, touch, and propioception in mammals. L. Kang, et al., Neuron, 67:381-91, 2010. Evaluations by Rachel Wilson, Harvard Medical School; Andy Groves, Baylor College of Medicine; Paul Garrity, Brandeis Univ; Roger Hardie, Univ of Cambridge. Free F1000 Evaluation 6. Two receptors explain MS? Rare, dual-receptor T-cells activated by a viral infection may be at the root of multiple sclerosis, providing a possible explanation for how other autoimmune diseases are initiated as well. Q. Ji, et al., Nat Immunol, 11:628-34, 2010. Evaluations by E. Charles Snow, Univ. of Kentucky Medical Center; Nick Gascoigne, The Scripps Research Institute; Barry Rouse, Univ of Tennessee; Ken Coppieters and Matthias von Herrath, La Jolla Institute for Allergy and Immunology. Free F1000 Evaluation 7. Hear and now Colored scanning electron micrograph of a section through the human inner ear. G. Brederg/Photo Researchers, Inc. Researchers coaxed embryonic stem cells and reprogrammed adult mouse cells into becoming the sensory hair cells that normally reside in the mammalian inner ear, thus demonstrating the steps necessary to regenerate the notoriously irreplaceable regulators of hearing and balance. K. Oshima, et al., Cell, 141:704-16, 2010. Evaluations by Nicolas Daudet and Azel Zine, INSERM U583; Ajay Chitnis, NICHD/NIH; Andy Groves, Baylor Coll of Med. Free F1000 Evaluation The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Neuroscience, as calculated on October 7, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com/. Related stories: Top 7 in developmental biology Top 7 immunology papers Read more: Top 7 papers in neuroscience - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/news/display/57742/#ixzz12HWYulHU
http://www.the-scientist.com/news/display/57742/ Top 7 papers in neuroscience Check out the hottest papers in neuroscience and related fields, as ranked by F1000 1. Epigenetics in mind The body's tendency to silence the expression of one parental allele in favor of the other -- a practice known as genomic imprinting -- is much more widespread in the brain than scientists have believed, according to a new genome-wide study in mice. Surprisingly, more than 1300 genes in the mouse brain appear to exhibit parent-of-origin epigenetic effects. Kessa Ligerro Wikimedia Commons C. Gregg, et al., Science, 329:643-8, 2010. Evaluations by Matt E. Carter and Luis de Lecea, Stanford Univ; Joachim Messing, Rutgers Univ; Yoshiho Ikeuchi and Azad Bonni, Harvard Medical School; David Sweatt, University of Alabama at Birmingham. Free F1000 Evaluation 2. Mechanotransduction proteins found A family of proteins, called Piezos, has been identified as important players in mechanically activated ion channels, which make possible several senses, such hearing, touch and pain sensation. B. Coste, et al., Science, 330:55-60, 2010. Evaluations by Felix Viana, UMH Instituto de Neurociencias; Paul Garrity, Brandeis Univ; Bernd Nilius, KU Leuven. Free F1000 Evaluation 3. Translation goes local Protein synthesis is a complicated game, but for the first time researchers have shown direct interaction between a transmembrane receptor, called DCC, with translational machinery in neurons, a step that likely facilitates localized protein manufacture. J. Tcherkezian, et al., Cell, 141:632-44, 2010. Evaluations by Kristen Kwan and Chi-Bin Chien, Univ Utah; Jacki Heraud and Michael Kiebler, Ctr for Brain Res, Med Univ Vienna, Austria; Wes Kroeze and Bryan Roth, Univ North Carolina; Luc Desgroseillers, Univ Montreal, Canada; Linda Columbus, Univ Virginia. Free F1000 Evaluation 4. Third one's the charm By comparing the three conformations in the crystal structure of a key microbacterial transporter protein, researchers propose a model for how the protein -- similar to those involved in mammalian neurotransmission -- moves substrates across the membrane. T. Shimamura, et al., Science, 328:470-3, 2010. Evaluations by Louis De Felice, Virginia Commonwealth Univ; Baruch Kanner, Hebrew Univ Hadassah Medical School, Israel; Robert Vandenberg, Univ of Sydney, Australia; Gary Rudnick, Yale Univ School of Medicine. Free F1000 Evaluation 5. Source of mechanotransduction? Researchers pinpoint the molecular identity of a mechanosensitive channel in C. elegans, suggesting a possible starting point for the hunt for mechanotransduction channels mediating hearing, touch, and propioception in mammals. L. Kang, et al., Neuron, 67:381-91, 2010. Evaluations by Rachel Wilson, Harvard Medical School; Andy Groves, Baylor College of Medicine; Paul Garrity, Brandeis Univ; Roger Hardie, Univ of Cambridge. Free F1000 Evaluation 6. Two receptors explain MS? Rare, dual-receptor T-cells activated by a viral infection may be at the root of multiple sclerosis, providing a possible explanation for how other autoimmune diseases are initiated as well. Q. Ji, et al., Nat Immunol, 11:628-34, 2010. Evaluations by E. Charles Snow, Univ. of Kentucky Medical Center; Nick Gascoigne, The Scripps Research Institute; Barry Rouse, Univ of Tennessee; Ken Coppieters and Matthias von Herrath, La Jolla Institute for Allergy and Immunology. Free F1000 Evaluation 7. Hear and now Colored scanning electron micrograph of a section through the human inner ear. G. Brederg/Photo Researchers, Inc. Researchers coaxed embryonic stem cells and reprogrammed adult mouse cells into becoming the sensory hair cells that normally reside in the mammalian inner ear, thus demonstrating the steps necessary to regenerate the notoriously irreplaceable regulators of hearing and balance. K. Oshima, et al., Cell, 141:704-16, 2010. Evaluations by Nicolas Daudet and Azel Zine, INSERM U583; Ajay Chitnis, NICHD/NIH; Andy Groves, Baylor Coll of Med. Free F1000 Evaluation The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Neuroscience, as calculated on October 7, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com/. Related stories: Top 7 in developmental biology Top 7 immunology papers Read more: Top 7 papers in neuroscience - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/news/display/57742/#ixzz12BrGXx5v
http://www.the-scientist.com/blog/display/57662/ News: Top 7 papers in neuroscience Posted by Jef Akst Comment on this news story 1. How neurons grow There's another layer of complexity in the developing nervous system: Spontaneous neuronal activity can regulate the differentiation of neurons, which can in turn affect swimming behavior in frog larvae. M. Demarque et al., Neuron 2010 Jul 29 67(2):321-34. Eval by Keith Sillar, University of St Andrews; Judith S Eisen, University of Oregon; Antonia Marin-Burgin and Alejandro Schinde, Leloir Institute ID: 4525956 2. Big role for astrocytes Neurons transfected with a disease- associated huntingtin protein Image: Wikimedia commons, Dr. Steven Finkbeiner, Gladstone Institute of Neurological Disease Once thought to be mere supporting cells, astrocytes in the brainstem are highly chemosensitive and appear to play a role in breathing. A.V. Gourine et al., Science 2010 Jul 30 329(5991):571-5. Eval by Tom Finger, Univ. Colorado Denver Sch. Medicine; Matt E Carter and Luis de Lecea, Stanford University ID: 4672017 3. Retina, redux Photosensitive ganglion cells, which were only discovered in the mammalian retina in the early 1990s, play a greater role in visual function than previously believed, suggesting that the current understanding of retinal physiology may need to be revisited. J.L. Ecker et al., Neuron 2010 Jul 15 67(1):49-60. Eval by Roger Hardie, University of Cambridge; Steven Repper, University of Massachusetts Medical School ID: 4242997 4. Addiction answers Drug addiction may be caused by a loss in synaptic plasticity, which inhibits new learning and makes drug use more compulsive. F. Kasanetz et al., Science 2010 Jun 25 328(5986):1709-12. Eval by Charles Pickens, Donna Calu and Yavin Shaham, National Institute on Drug Abuse; Rainer Spanagel, Central Institute of Mental Health, Germany Pharmacology Drug Discovery ID: 4077956 5. Source of mechanotransduction? Researchers pinpoint the molecular identity of a mechanosensitive channel in C. elegans, suggesting a possible starting point for the hunt for mechanotransduction channels mediating hearing, touch, and propioception in mammals. L. Kang et al., Neuron 2010 Aug 12 67(3):381-391. Eval by Roger Hardie, University of Cambridge; Paul Garrity, Brandeis University ID: 4765957 6. How huntingtin hurts New clues have emerged to how a defective form of the huntingtin protein may cause the deadly changes that lead to Huntington's disease -- by potentially disrupting the process of neurogenesis, thereby decreasing neural progenitor cells. J.D. Godin et al., Neuron 2010 Aug 12 67(3):392-406. Eval by Monte Gates, Keele University; Mark Fortini, National Cancer Institute ID: 4903959 7. Mass migration in vivo Using a novel technique, researchers discover clues about what guides the migration of neural crest cells in a developing embryo, providing insights into both embryogenesis and cancer metastasis, where collective cell migration also plays a role. E. Theveneau et al., Dev Cell 2010 Jul 20 19(1):39-53. Eval by Ravi Desai and Christopher Chen, University of Pennsylvania; Tina Schwabe and Thomas Clandinin, Stanford University ID: 4576956 The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Neuroscience, as calculated on August 27, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com. Related stories: Top 7 immunology papers Top 7 papers in neuroscience Top 7 papers in neuroscience Read more: Top 7 papers in neuroscience - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/blog/display/57662/#ixzz0yEasO420
Derong Liu's Top Ten Papers F. Y. Wang, N. Jin, D. Liu , and Q. Wei, Adaptive dynamic programming for finite horizon optimal control of discrete-time nonlinear systems with epsilon-error bound, IEEE Transactions on Neural Networks , accepted for publication. D. Liu , Z. Pang, and Z. Wang, Epileptic seizure prediction by a system of particle filter associated with a neural network, EURASIP Journal on Advances in Signal Processing , vol.2009, article ID 638534, 10 pages, 2009. doi:10.1155/2009/638534. D. Liu and Y. Cai, Taguchi method for solving the economic dispatch problem with nonsmooth cost functions, IEEE Transactions on Power Systems , vol. 20, no. 4, pp. 2006-2014, Nov. 2005. D. Liu , Y. Zhang, and H. Zhang, A self-learning call admission control scheme for CDMA cellular networks, IEEE Transactions on Neural Networks , vol.16, no.5, pp.1219-1228, Sept. 2005. D. Liu and A. Molchanov, Asymptotic stability of a class of linear discrete systems with multiple independent variables, Circuits, Systems and Signal Processing, vol.22, no.3, pp.307-324, May-June 2003. D. Liu , E. I. Sara, and W. Sun, Nested auto-regressive processes for MPEG-encoded video traffic modeling, IEEE Transactions on Circuits and Systems for Video Technology , vol.11, no.2, pp.169-183, Feb. 2001. D. Liu and Z. Lu, A new synthesis approach for feedback neural networks based on the perceptron training algorithm, IEEE Transactions on Neural Networks, vol.8, no.6, pp.1468-1482, Nov. 1997. D. Liu and A. N. Michel, Sparsely interconnected neural networks for associative memories with applications to cellular neural networks, IEEE Transactions on Circuits and Systems-II: Analog and Digital Signal Processing, vol.41, no.4, pp.295-307, Apr. 1994. D. Liu and A. N. Michel, Stability analysis of state-space realizations for two-dimensional filters with overflow nonlinearities, IEEE Transactions on Circuits and Systems-I: Fundamental Theory and Applications, vol.41, no.2, pp.127-137, Feb. 1994. D. Liu and A. N. Michel, Asymptotic stability of discrete-time systems with saturation nonlinearities with applications to digital filters, IEEE Transactions on Circuits and Systems-I: Fundamental Theory and Applications, vol.39, no.10, pp.798-807, Oct. 1992.
http://www.the-scientist.com/blog/display/57574/ News: Top 7 papers in neuroscience Posted by Megan Scudellari Comment on this news story #1 Neurons complete hippocampus loop There's a new, important function for a once-obscure cell population in the brain: CA2 pyramidal neurons, a subset of cells in the hippocampus, form a link between electrical inputs and outputs in the hippocampus. V. Chevaleye et al., Strong CA2 pyramidal neuron synapses define a powerful disynaptic cortico-hippocampal loop, Neuron, 66:560-72, 2010. Eval by Stephen Fitzjohn and Graham Collingridge, MRC Centre for Synaptic Plasticity, UK; Johannes Hell, University of California, Davis. Neurons in the mouse brain Image: Wikimedia Commons, Neurollero #2 Non-overlapping neurons The medial entorhinal cortex, a hub for memory and navigation in the brain, consists of two tangled but functionally separate networks that have different long-range axonal targets, and thus may be involved in different functions in the brain. The finding offers insights to how neural networks function, and -- in conditions like epilepsy -- dysfunction. C. Varga et al., Target-selective GABAergic control of entorhinal cortex output, Nat Neurosci, 13:822-4, 2010. Eval by Edvard Moser, Norwegian University of Science and Technology, Norway; Jeff Isaacson, University of California, San Diego. #3 We're going to need a bigger model In a detailed mathematical analysis, researchers analyze the capacity of computational models to model neuronal oscillations -- the repetitive rise and fall of membrane potentials. They find that current single-cell oscillation models are not adequate, and there is a need for additional computational models to assess this mechanism. M.W. Remme et al., Democracy-independence trade-off in oscillating dendrites and its implications for grid cells, Neuron, 66:560-72, 2010. Eval by Lisa Giocomo and Edvard Moser, Norwegian University of Science and Technology, Norway; Neil Burgess, University College London. #4 Key step to making dendrites For the first time, researchers demonstrate that a protein that fuses membranes instructs the development of dendrites in C. elegans. The protein, EFF-1, causes overlapping branches to fuse together, a novel control mechanism for the poorly understood morphogenesis of dendrites. M. Oren-Suissa et al., The fusogen EFF-1 controls sculpting of mechanosensory dendrites, Science, 328:1285-8, 2010. Eval by Tina Schwabe and Thomas Clandinin, Stanford University, California; Andrew Chisholm, University of California, San Diego. #5 How amyloid kills synapses New findings suggest an explanation for why amyloid causes synapses to fail in Alzheimer's and other diseases: The binding of amyloid beta oligomers causes glutamate receptors in synaptic membranes to form clusters, resulting in increased intracellular calcium and eventual deterioration of the synapse. M. Renner et al., Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5, Neuron, 66:739-54, 2010. Eval by Joel Bockaert, Institute of Functional Genomics, France; Hui-Chen Lu and Kenneth Mackie, Indiana University. #6 New mechanism for synaptic plasticity Researchers have uncovered another key mechanism behind one of the most important processes in learning and memory, synaptic plasticity. Specifically, two signaling molecules, BRAG2 and Arf6, trigger endocytosis of AMPA receptors in the brain, inducing long-term depression (LTD), a long-lasting reduction in the sensitivity of neurons and a well-known form of synaptic plasticity. R. Scholz et al., AMPA receptor signaling through BRAG2 and Arf6 critical for long-term synaptic depression, Neuron, 66:768-80, 2010. Eval by Stephen Fitzjohn and Graham Collingridge, MRC Centre for Synaptic Plasticity, UK; Johannes Hell, University of California, Davis. #7 Cell division affects cell fate Through live imaging of a zebrafish embryo, researchers show that asymmetrical cell division is important in establishing cell fate in the vertebrate central nervous system. P. Alexandre et al., Neurons derive from the more apical daughter in asymmetric divisions in the zebrafish neural tube, Nat Neurosci, 13:673-9, 2010. Eval by Judith Eisen, University of Oregon; Caren Norden and William Harris, University of Cambridge, UK. The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Neuroscience, as calculated on July 22, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com. Related stories: Top 7 immunology papers Top 7 cell biology papers Read more: Top 7 papers in neuroscience - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/blog/display/57574/#ixzz0v1W0PMgy
Comment on my papers in arxiv.org, please! Dear Sir or Madam: Comment on my papers in arxiv.org, please! Any criticism is welcome! English and Chinese are limited for you, because I cannot read other languages. Sorry! Thank you very much for your criticisms and comments! Yours sincerely Zheng-Ling YANG
http://www.the-scientist.com/blog/display/57552/ News: Top 7 cell biology papers Posted by Jef Akst Comment on this news story #1 Gene for autoimmunity Rare genetic variants in the protein sialic acid acetylesterase (SASE) are linked to common human autoimmune diseases, including type 1 diabetes, arthritis, and Crohn's disease. In mice, defects in the protein have been linked to problems in B-cell signaling and the development of auto-antibodies. I. Surolia, et al., Functionally defective germline variants of sialic acid acetylesterase in autoimmunity, Nature , 466:243-7. Epub 2010 Jun 16. Eval by Mark Anderson, UCSF Diabetes Center; Anthony DeFranco, University of California, San Francisco; Takeshi Tsubata, Tokyo Medical University, Japan. Mouse cingulate cortex neurons Image: Wikimedia commons, Shushruth #2 Cell mobility illuminated Using light to activate a the protein Rac in a single cell, researchers show how the protein can induce a group of epithelial cells to polarize en masse, suggesting that these cells can sense movement as a group. X. Wang, et al., Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo, Nat Cell Biol , 12:591-7. Epub 2010 May 16. Eval by Susan Hopkinson and Jonathan Jones, Northwestern University Medical School; Ekaterina Papusheva and Carl-Phillip Heisenberg, Max-Plank-Institute for Molecular Cell Biology and Genetics; Jonathan Chernoff, Fox Chase Cancer Center. #3 How the brain communicates Reproducing the electrical activity of the neurons in the mouse cortex, researchers demonstrate how different layers of the brain communicate to piece together information from a wide range of sensory inputs -- a process that many neuroscientists consider a major mystery in the field. H. Adesnik and M. Scanziani. Lateral competition for cortical space by layer-specific horizontal circuits, Nature , 464:1155-60, 2010. Eval by Aguan Wei and Jan-Marino Ramirez, University of Washington; James Cottam and Michael Hausser, University College London. #4 Backwards-working neurons Normally neurons respond strongly to synapses located closer to the cell's center and weakly to those located on the cell's tips. But the authors found that certain neurons important in spatial memory react more strongly to the distant brain signals than those from nearby neurons. V. Chevaleyre and SA Siegelbaum. Strong CA2 pyramidal neuron synapses define a powerful disynaptic cortico-hippocampal loop, Neuron , 66:560-72, 2010. Eval byStephen M Fitzjohn and Graham Collingridge, MRC centre for Synaptic Plasticity; Johannes Hell, University of California, Davis. #5 Cell-swallowing proteins Researchers identify two proteins vital to -- and perhaps responsible for initiating -- the way eukaryotic cells take up ligands bound to the surface receptors into membrane-bound vesicles, a process essential for a vast number of cellular functions, including nutrient uptake, receptor signaling, pathogen entry, and drug delivery. WM Henne, et al., FCHo proteins are nucleators of clathrin-mediated endocytosis, Science , 328:1281-4, 2010. Eval by Martin Lowe, University of Manchester; Pekka Lappalainen, Institute of Biotechnology, Finland. #6 Less genetic dark matter In opposition to the idea that much of the mammalian genome is uselessly transcribed into non-functional RNA molecules, researchers demonstrate that there is relatively little RNA derived from the expanses of DNA in between functional genes. H van Bakel et al., Most 'dark matter' transcripts are associated with known genes, PLoS Biol , 2010 May 18;8(5):e1000371. Eval by Daniel Reines, Emory University School of Medicine; Adnane Sellam and Andre Nantel, National Reseasrch Council of Canada. #7 Death receptor helps cancer live The apoptosis receptor DC95 that induces cell death may also promote cancer growth, providing a new possible target for cancer therapies. L. Chen et al., CD95 promotes tumour growth, Nature , 465:492-6, 2010. Eval by Sharad Kumar, Centre for Cancer Biology, Austrailia; Astar Winoto, University of California, Berkeley. The F1000 Top 7 is a snapshot of the highest ranked articles from a 30-day period on Faculty of 1000 Biochemistry, as calculated on July 8, 2010. Faculty Members evaluate and rate the most important papers in their field. To see the latest rankings, search the database, and read daily evaluations, visit http://f1000.com. Jennifer Welsh contributed to this article. Related stories: Top 7 biochemistry papers Top 7 From F1000 Top 7 From F1000 Read more: Top 7 cell biology papers - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/blog/display/57552/#ixzz0tbXO8p00
May 27, 2010 Top 7 from F1000 See the highest ranked papers from F1000 Biology By The Scientist Staff Naturally selected Ninety thousand ways to make you smarter By Sarah Greene Is this life? We're opening up our archives, and returning to our 2006 article on the progress and challenges of synthetic biology, in honor of last week's landmark announcement By Jack Lucentini How can I be sure? The Faculty's recent picks: sex and the single cell; mile high club; physician, heal thyself By Richard Grant miRNA makes cancer cells slick A miRNA associated with breast cancer inhibits E-cadherin expression, causing increased cell motility and invasiveness, yielding new insights into how the cancer spreads. Ma et al. 2010 Nat Cell Biol . Evaluated by A Migliaccio F Auricchio The diversity maker How a single transcription factor, Ste12, binds to DNA is behind the variation in phenotype that drives individual diversity in yeast. Gibson et al. 2010 Science . Evaluated by S Zeller B Schmid 10 retractions and counting A Mayo Clinic immunology lab has pulled 10 papers so far, with about five more expected, and cancelled a clinical trial By Jef Akst Senior Lancet editor sacked The cause, she says: Violating the confidentiality policy by distributing the draft version of a published (and edited) editorial By Bob Grant Death star A fax that Michael Hengartner sent to his mentor helped turn apoptosis into a Nobel Prize-winning pathway By Karen Hopkin Oil spill is boon to bacteria Effects of microbial proliferation up the food chain unknown By Bob Grant Data after death Most scientists don't think about what will happen to a lab after its PI dies until, tragically, they must By Jef Akst Misconduct case drags on Blood researcher fights to be reinstated at the University of Washington after a 7-year investigation By Jef Akst News in a nutshell DNA directs mutations; top 10 new species; CSI: dog poop By Alison McCook Billion-dollar babies The story of scientists who came up with ideas that recently convinced Pharma to give them millions of dollars By Jef Akst Digital upgrade How to choose your lab's next electronic lab notebook By Amber Dance
ScienceWatch.com has tracked the following New Hot Papers which had the highest percentage increase in citations in Essential Science Indicators SM from Thomson Reuters from the sixth bimonthly period of 2009 to the first bimonthly period of 2010, a total of 1,885 hot papers were identified, of which 1,248 (66.2%) were new. Some papers have comments sent in by the author(s) of the paper which may include images and descriptions of their work. 详细请见 http://sciencewatch.com/dr/nhp/2010/10maynhp/
The Red-Hot Research Papers of 2009 Rank Paper Citations 1 E. Komatsu, et al. , Five-year Wilkinson Microwave Anisotropy Probe observations: Cosmological interpretation, Astrophys. J. Suppl. Ser. , 180(2): 330-76, February 2009. 659 2 J. Dunkley, et al. , Five-year Wilkinson Microwave Anistropy Probe observations: Likelihoods and parameters from the WMAP data, Astrophys. J. Suppl. Ser. , 180(2): 306-29, February 2009. 274 3 O. Adriani, et al. , An anomalous positron abundance in cosmic rays with energies 1.5-100 GeV, Nature , 458(7238): 607-9, 2 April 2009. 173 4 W. Duckworth, et al. , Glucose control and vascular complications in veterans with type 2 diabetes, New Engl. J. Med. , 360(2): 129-39, 8 January 2009. 172 5 G. Hinshaw, et al. , Five-year Wilkinson Microwave Anisotropy Probe observations: Data processing, sky maps, and basic results, Astrophys. J. Suppl. Ser. , 180(2): 225-45, February 2009. 171 6 F.H. Schrder, et al. , Screening and prostate-cancer mortality in a randomized European study, New Engl. J. Med. , 360(13): 1320-8, 26 March 2009. 148 7 Novel Swine-Origin Influenza A ( H1N1 ) Virus Investigation Team (F.S. Dawood, et al. ), Emergence of a novel swine-origin influenza A (H1N1) virus in humans, New Engl. J. Med. , 360(25): 2605-15, 18 June 2009. 141 8 N. Arkani-Hamed, et al. , A theory of dark matter, Phys. Rev. D , 79(1): No. 015014, January 2009. 137 9 G.L. Andriole, et al. , Mortality results from a randomized prostate-cancer screening trial, New Engl. J. Med. , 360(13): 1310-9, 26 March 2009. 130 10 J.L. Mega, et al. , Cytochrome P-450 polymorphisms and response to clopidogrel, New Engl. J. Med. , 360(4): 354-62, 22 January 2009. 120 11 S. Finfer, et al. , Intensive versus conventional glucose control in critically ill patients, New Engl. J. Med. , 360(13): 1283-97, 26 March 2009. 109 12 O. Adriani, et al. , New measurement of the antiproton-to-proton flux ratio of up to 100GeV in the cosmic radiation, Phys. Rev. Lett. , 102(5): No. 051101, 6 February 2009. 108 13 K.S. Kim, et al. , Large-scale pattern growth of graphene films for stretchable transparent electrodes, Nature , 457(7230): 706-10, 5 February 2009. 102 14 S.M. Lippman, et al. , Effect of selenium and vitamin E on risk of prostate cancer and other cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT), JAMA , 301(1): 39-51, 7 January 2009. 102 15 D.C. Elias, et al. , Control of graphenes properties by reversible hydrogenation: Evidence for graphane, Science , 323(5914): 610-3, 30 January 2009. 96 16 Z. Ahmed, et al. , Search for weakly interacting massive particles with the first five-tower data from the Cryogenic Dark Matter Search at the Soudan Underground Laboratory, Phys. Rev. Lett. , 102(1): No. 011301, 9 January 2009. 95 17 M. Cirelli, Model-independent implications of the e(+/-), P (over-bar) cosmic ray spectra on properties of Dark Matter, Nucl. Phys. B , 813(1-2): 1-21, 21 May 2009. 95 18 C. Fraser, et al. , Pandemic potential of a strain of influenza A (H1N1): Early findings, Science , 324(5934): 1557-61, 19 June 2009. 93 19 C.J. Willer, et al. , Six new loci associated with body mass index highlight a neuronal influence on body weight regulation, Nature Genetics , 41(1): 25-34, January 2009. 91 20 A. Gustavsson, Algebraic structures on parallel M2 branes, Nucl. Phys. B , 811(1-2): 66-76, 11 April 2009. 89 21 T. Simon, et al. , Genetic determinants of response to clopidogrel and cardiovascular events, New Engl. J. Med. , 360(4): 363-75, 22 January 2009. 85 22 M.R. Nolta, et al. , Five-year Wilkinson Microwave Anisotropy Probe observations: Angular power spectra, Astrophys. J. Suppl. Ser. , 180(2): 296-305, February 2009. 84 23 K. Woltjen, et al. , piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells, Nature , 458(7239): 766-70, 9 April 2009. 83 24 P.M. Ho, et al. , Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome, JAMA , 301(9): 937-44, 4 March 2009. 81 25 A.A. Abdo, et al. , Measurement of the cosmic ray e + + e - spectrum from 20 GeV to 1 TeV with the Fermi Large Area Telescope, Phys. Rev. Lett. , 102(18): No. 181101, 8 May 2009. 80 26 V. Cvetkovic, et al. , Multiband magnetism and superconductivity in Fe-based compounds, EPL , 85(3): No. 37002, February 2009. 80 27 P. Horava, Quantum gravity at a Lifshitz point, Phys. Rev. D , 79(8): No. 084008, April 2009. 77 28 P.W. Serruys, et al. , Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease, New Engl. J. Med. , 360(10): 961-72, 5 March 2009. 77 29 M. Paez-Ribes, et al. , Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis, Cancer Cell , 15(3): 220-31, 3 March 2009. 77 30 S.H. Park, et al. , Bulk heterojunction solar cells with internal quantum efficiency approaching 100%, Nature Photonics , 3(5): 297-302, May 2009. 70 31 G. Thorleifsson, et al. , Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity, Nature Genetics , 41(1): 18-24, January 2009. 70 32 K. Kaji, et al. , Virus-free induction of pluripotency and subsequent excision of reprogramming factors, Nature , 458(7239): 771-5, 9 April 2009. 69 33 P.L. Alireza, et al. , Superconductivity up to 29 K in SrFe 2 As 2 and BaFe 2 As 2 at high pressures, J. Physics- Condensed Matter , 21(1): No. 012208, 7 January 2009. 69 34 A. Reina, et al. , Large area, few-layer graphene films on arbitrary substrates by chemical vapor deposition, Nano Letters , 9(1): 30-5, January 2009. 69 35 F. Soldner, et al. , Parkinsons disease patient-derived induced pluripotent stem cells free of viral reprogramming factors, Cell , 136(5): 964-77, 6 March 2009. 68 36 J.Y. Yu, et al. , Human induced pluripotent stem cells free of vector and transgene sequences, Science , 324(5928): 797-801, 8 May 2009. 67 37 J.M.L. Ebos, et al. , Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis, Cancer Cell , 15(3): 232-9, 3 March 2009. 66 38 A. Garber, et al. , Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomized, 52-week, phase III, double-blind, parallel-treatment trial, Lancet , 373(9662): 473-81, 7 February 2009. 65 39 R.J. Garten, et al. , Antigenic and genetic characteristics of the swine-origin 2009 A(H1N1) influenza viruses circulating in humans, Science , 325(5937): 197-201, 10 July 2009. 64 40 F. Wang, et al. , Functional renormalization-group study of the pairing symmetry and pairing mechanism of the FeAs-based high-temperature superconductor, Phys. Rev. Lett. , 102(4): No. 047005, 30 January 2009. 64 41 J. Tol, et al. , Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer, New Engl. J. Med. , 360(6): 563-72, 5 February 2009. 63 42 T.E. Klein, et al. , Estimation of the warfarin dose with clinical and pharmacogenetic data, New Engl. J. Med. , 360(8): 753-64, 19 February 2009. 62 43 J.P. Collet, et al. , Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study, Lancet , 373(9660): 309-17, 24 January 2009. 61 44 B.C. Fellstrom, et al. , Rosuvastatin and cardiovascular events in patients undergoing hemodialysis, New Engl. J. Med. , 360(14): 1395-1407, 2 April 2009. 60 SOURCE: ISI Web of Knowledge from Thomson Reuters (Citations recorded as of late December 2009). http://sciencewatch.com/ana/fea/10maraprFea/
H1N1 Flu - September 2009 Top Papers - 10 years | 2 years The baseline time span for this database is 1999-June 30, 2009 (third bimonthly period 2009). The resulting database contained 8,611 (10 years) and 3,521 (2 years) papers. To construct the top 20 papers lists for the past decade and the past two years, the papers were further narrowed down by the topic OR title keywords: (influenza A) OR Topic=(swine AND flu) OR Title=(swine AND influenza). This adjustment resulted in the top 20 papers being selected from a pool of 162 (10 years) and 109 (2 years) papers. ***Article 1 Total Cites: 73 Article Title: The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo Authors: Ives, JAL, Carr, JA, Mendel, DB, Tai, CY, Lambkin, R, Kelly, L, Oxford, JS, Hayden, FG, Roberts, NA Journal: ANTIVIRAL RESEARCH Volume: 55 Page: 307-317 Year: 2002 Addresses: ROCHE PROD LTD, Welwyn Garden City, England GILEAD SCI INC, Foster City, CA, USA UNIV LONDON QUEEN MARY WESTFIELD COLL, Retrosceen Virol Ltd, London, England UNIV VIRGINIA, Sch Med, Charlottesville, VA, USA Roche Prod Ltd, 40 Broadwater Rd, Welwyn Garden City, England ***Article 2 Total Cites: 59 Article Title: Evaluation of trivalent, live, cold-adapted (CAIV-T) and inactivated (TIV) influenza vaccines in prevention of virus infection and illness following challenge of adults with wild-type influenza A (H1N1), A (H3N2), and B viruses Authors: Treanor, JJ, Kotloff, K, Betts, RF, Belshe, R, Newman, F, Iacuzio, D, Wittes, J, Bryant, M Journal: VACCINE Volume: 18 Page: 899-906 Year: 1999 Addresses: UNIV ROCHESTER, Sch Med, Dept Med, Infect Dis Unit, Rochester, NY, USA UNIV MARYLAND, Dept Med, Baltimore, MD, USA ST LOUIS UNIV, Dept Med, St Louis, MO, USA NIAID, Div Microbiol Infect Dis, NIH, Bethesda, MD, USA STAT COLLABORAT, Washington, DC, USA AVIRON, Mt View, CA, USA Univ Rochester, Sch Med, Dept Med, Infect Dis Unit, Rochester, NY, USA ***Article 3 Total Cites: 53 Article Title: Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide Authors: Deyde, VM, Xu, XY, Bright, RA, Shaw, M, Smith, CB, Zhang, Y, Shu, YL, Gubareva, LV, Cox, NJ, Klimov, AI Journal: J INFECT DIS Volume: 196 Page: 249-257 Year: 2007 Addresses: CTR DIS CONTROL PREVENT, Influenza Div, Natl Ctr Immunizat Resp Dis, Atlanta, GA, USA Natl Inst Viral Dis Control Prevent, State Key Lab Dis Prevent Control, Beijing, Peoples R China Ctr Dis Control Prevent, Influenza Div, Natl Ctr Immunizat Resp Dis, Mail Stop G-16,1600 Clifton Rd, Atlanta, GA, USA ***Article 4 Total Cites: 44 Article Title: Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: An experiment of nature Authors: Epstein, SL Journal: J INFECT DIS Volume: 193 Page: 49-53 Year: 2006 Addresses: US FDA, Lab Immunol Dev Biol, Div Cellular Gene Therapies, Off Cellular Tissue Gene Therapies,Ctr Biol Eva, Rockville, MD, USA US FDA, OCTGT, CBER, DCGT, Rockville, MD, USA ***Article 5 Total Cites: 40 Article Title: Antigenic and genetic diversity among swine influenza A H1N1 and H1N2 viruses in Europe Authors: Marozin, S, Gregory, V, Cameron, K, Bennett, M, Valette, M, Aymard, M, Foni, E, Barigazzi, G, Lin, Y, Hay, A Journal: JOURNAL OF GENERAL VIROLOGY Volume: 83 Page: 735-745 Year: 2002 Addresses: NATL INST MED RES, London, England UNIV LYON 1, Virol Lab, Lyon, France IST ZOOPROFILATT SPERIMENTALE LOMBARDIA EMILIA, Parma, Italy Natl Inst Med Res, Mill Hill, London, England ***Article 6 Total Cites: 39 Article Title: Estimating efficacy of trivalent, cold-adapted, influenza virus vaccine (CAIV-T) against influenza A (H1N1) and B using surveillance cultures Authors: Halloran, ME, Longini, IM, Gaglani, MJ, Piedra, PA, Chu, H, Herschler, GB, Glezen, WP Journal: AM J EPIDEMIOL Volume: 158 Page: 305-311 Year: 2003 Addresses: EMORY UNIV, Rollins Sch Publ Hlth, Dept Biostat, Atlanta, GA, USA TEXAS AM UNIV, Sect Pediat Infect Dis,Coll Med, Dept Pediat,Scott Sherwood Brindley Fdn, Scott White Mem Hosp Clin, Temple, TX, USA BAYLOR COLL MED, Dept Mol Virol Microbiol, Houston, TX, USA BAYLOR COLL MED, Dept Pediat, Houston, TX, USA Emory Univ, Rollins Sch Publ Hlth, Dept Biostat, 1518 Clifton Rd NE, Atlanta, GA, USA ***Article 7 Total Cites: 38 Article Title: Direct and total effectiveness of the intranasal, live-attenuated, trivalent cold-adapted influenza virus vaccine against the 2000-2001 influenza A(H1N1) and B epidemic in healthy children Authors: Gaglani, MJ, Piedra, PA, Herschler, GB, Griffith, ME, Kozinetz, CA, Riggs, MW, Fewlass, C, Halloran, ME, Longini, IM, Glezen, WP Journal: ARCH PEDIAT ADOL MED Volume: 158 Page: 65-73 Year: 2004 Addresses: TEXAS AM UNIV, Coll Med, Scott White Mem Hosp Clin,Syst Hlth Sci Ctr, Dept Pediat,Sect Pediat Infect Dis, Temple, TX, USA BAYLOR COLL MED, Dept Mol Virol, Houston, TX, USA BAYLOR COLL MED, Dept Microbiol, Houston, TX, USA BAYLOR COLL MED, Dept Pediat, Houston, TX, USA EMORY UNIV, Rollins Sch Publ Hlth, Dept Biostat, Atlanta, GA, USA Texas AM Univ, Coll Med, Scott White Mem Hosp Clin,Syst Hlth Sci Ctr, Dept Pediat,Sect Pediat Infect Dis, Temple, TX, USA ***Article 8 Total Cites: 32 Article Title: Detection and subtyping of swine influenza H1N1, H1N2 and H3N2 viruses in clinical samples using two multiplex RT-PCR assays Authors: Choi, YK, Goyal, SM, Kang, SW, Farnham, MW, Joo, HS Journal: J VIROL METHODS Volume: 102 Page: 53-59 Year: 2002 Addresses: UNIV MINNESOTA, Dept Clin Populat Sci, St Paul, MN, USA UNIV MINNESOTA, Dept Vet Diagnost Med, St Paul, MN, USA UNIV MINNESOTA, Dept Anim Sci, St Paul, MN, USA Univ Minnesota, Dept Clin Populat Sci, 385 Anim Sci Vet Med,1988 Fitch Ave, St Paul, MN, USA ***Article 9 Total Cites: 26 Article Title: Systemic and mucosal immune responses to H1N1 influenza virus infection in pigs Authors: Larsen, DL, Karasin, A, Zuckerman, F, Olsen, CW Journal: VETERINARY MICROBIOLOGY Volume: 74 Page: 117-131 Year: 2000 Addresses: UNIV WISCONSIN, Sch Vet Med, Dept Pathobiol Sci, Madison, WI, USA UNIV ILLINOIS, Coll Vet Med, Dept Vet Pathobiol, Urbana, IL, USA Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, 2015 Linden Dr W, Madison, WI, USA ***Article 10 Total Cites: 25 Article Title: Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations Authors: Abed, Y, Goyette, N, Boivin, G Journal: ANTIMICROB AGENTS CH Volume: 49 Page: 556-559 Year: 2005 Addresses: UNIV LAVAL, CHUQ, Res Ctr Infect Dis, Quebec City, Canada UNIV LAVAL, Quebec City, Canada CHU Laval, CHUQ, Res Ctr Infect Dis, Room RC-709,2705 Blvd Laurier St Foy, Quebec City, Canada ***Article 11 Total Cites: 25 Article Title: Characterization of avian H3N3 and H1N1 influenza A viruses isolated from pigs in Canada Authors: Karasin, AI, West, K, Carman, S, Olsen, CW Journal: JOURNAL OF CLINICAL MICROBIOLOGY Volume: 42 Page: 4349-4354 Year: 2004 Addresses: UNIV WISCONSIN, Dept Pathobiol Sci, Sch Vet Med, Madison, WI, USA UNIV SASKATCHEWAN, Dept Vet Microbiol, Saskatoon, Canada UNIV GUELPH, Hlth Anim Lab, Lab Serv Div, Guelph, Canada Univ Wisconsin, Dept Pathobiol Sci, Sch Vet Med, 2015 Linden Dr, Madison, WI, USA ***Article 12 Total Cites: 21 Article Title: Frequency of amantadine-resistant influenza A viruses during two seasons featuring cocirculation of H1N1 and H3N2 Authors: Saito, R, Sakai, T, Sato, I, Sano, Y, Oshitani, H, Sato, M, Suzuki, H Journal: JOURNAL OF CLINICAL MICROBIOLOGY Volume: 41 Page: 2164-2165 Year: 2003 Addresses: NIIGATA UNIV, Grad Sch Med Dent Sci, Dept Publ Hlth, Niigata, Japan Yoiko Pediat Clin, Niigata, Japan SANO CLIN, Niigata, Japan Niigata Univ, Grad Sch Med Dent Sci, Dept Publ Hlth, 1-757 Asahimachi Dori, Niigata, Japan ***Article 13 Total Cites: 19 Article Title: A simple restriction fragment length polymorphism-based strategy that can distinguish the internal genes of human H1N1, H3N2, and H5N1 influenza A viruses Authors: Cooper, LA, Subbarao, K Journal: JOURNAL OF CLINICAL MICROBIOLOGY Volume: 38 Page: 2579-2583 Year: 2000 Addresses: CTR DIS CONTROL PREVENT, Influenza Branch, Div Viral Rickettsial Dis, Natl Ctr Infect Dis, Atlanta, GA, USA Ctr Dis Control Prevent, Influenza Branch, Div Viral Rickettsial Dis, Natl Ctr Infect Dis, Atlanta, GA, USA ***Article 14 Total Cites: 19 Article Title: Efficacy of vaccination of pigs with different H1N1 swine influenza viruses using a recent challenge strain and different parameters of protection Authors: Van Reeth, K, Labarque, G, De Clercq, S, Pensaert, M Journal: VACCINE Volume: 19 Page: 4479-4486 Year: 2001 Addresses: GHENT UNIV, Fac Med Vet, Virol Lab, Merelbeke, Belgium State Univ Ghent, Fac Med Vet, Virol Lab, Salisburylaan 133, Merelbeke, Belgium ***Article 15 Total Cites: 18 Article Title: Identification of human H1N2 and human-swine reassortant H1N2 and H1N1 influenza a viruses among pigs in Ontario, Canada (2003 to 2005) Authors: Karasin, AI, Carman, S, Olsen, CW Journal: JOURNAL OF CLINICAL MICROBIOLOGY Volume: 44 Page: 1123-1126 Year: 2006 Addresses: UNIV WISCONSIN, Sch Vet Med, Dept Pathobiol Sci, Madison, WI, USA UNIV GUELPH, Lab Serv Div, Anim Hlth Lab, Guelph, Canada Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, 2015 Linden Dr, Madison, WI, USA ***Article 16 Total Cites: 18 Article Title: Comparison of colorimetric, fluorometric, and visual methods for determining anti-influenza (H1N1 and H3N2) virus activities and toxicities of compounds Authors: Smee, DF, Morrison, AC, Barnard, DL, Sidwell, RW Journal: J VIROL METHODS Volume: 106 Page: 71-79 Year: 2002 Addresses: UTAH STATE UNIV, Inst Antiviral Res, Dept Anim Dairy Vet Sci, Logan, UT, USA Utah State Univ, Inst Antiviral Res, Dept Anim Dairy Vet Sci, Logan, UT, USA ***Article 17 Total Cites: 17 Article Title: A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus Authors: Abed, Y, Goyette, N, Boivin, G Journal: ANTIVIRAL THERAPY Volume: 9 Page: 577-581 Year: 2004 Addresses: UNIV LAVAL, CHUQ, Res Ctr Infect Dis, Quebec City, Canada UNIV LAVAL, Quebec City, Canada CHU Laval, CHUQ, Res Ctr Infect Dis, Quebec City, Canada ***Article 18 Total Cites: 15 Article Title: Comparative analytical sensitivities of six rapid influenza A antigen detection test kits for detection of influenza A subtypes H1N1H3N2 and H5N1 Authors: Chan, KH, Lam, SY, Puthavathana, P, Nguyen, TD, Long, HT, Pang, CM, Chan, KM, Cheung, CY, Seto, WH, Peiris, JSM Journal: JOURNAL OF CLINICAL VIROLOGY Volume: 38 Page: 169-171 Year: 2007 Addresses: UNIV HONG KONG, Dept Microbiol, Hong Kong, Peoples R China Sriraj Hosp, Dept Microbiol, Bangkok, Thailand NATL INST VET RES, Hanoi, Vietnam NATL INST HYG EPIDEMIOL, Hanoi, Vietnam Univ Hong Kong, Dept Microbiol, Univ Pathol Bldg,Queen Mary Hosp Compound, Hong Kong, Peoples R China ***Article 19 Total Cites: 15 Article Title: Antigenic and molecular heterogeneity in recent swine influenza A(H1N1) virus isolates with possible implications for vaccination policy Authors: de Jong, JC, Heinen, PP, Loeffen, WLA, van Nieuwstadt, AP, Claas, ECJ, Bestebroer, TM, Bijlsma, K, Verweij, C, Osterhaus, ADME, Rimmelzwaan, GF, Fouchier, RAM, Kimman, TG Journal: VACCINE Volume: 19 Page: 4452-4464 Year: 2001 Addresses: ERASMUS UNIV ROTTERDAM, Natl Influenza Ctr, Dept Virol, Rotterdam, Netherlands RIVM, Natl Inst Publ Hlth Environm, Res Lab Infect Dis, Bilthoven, Netherlands ID Lelystad, Dept Mammalian Virol, Lelystad, Netherlands ANIM HLTH SERV, Boxtel, Netherlands Erasmus Univ, Natl Influenza Ctr, Dept Virol, POB 1738,Dr Molewaterplein 50, Rotterdam, Netherlands ***Article 20 Total Cites: 15 Article Title: Protection against a European H1N2 swine influenza virus in pigs previously infected with H1N1 and/or H3N2 subtypes Authors: Van Reeth, K, Gregory, V, Hay, A, Pensaert, M Journal: VACCINE Volume: 21 Page: 1375-1381 Year: 2003 Addresses: GHENT UNIV, Virol Lab, Fac Med Vet, Merelbeke, Belgium NATL INST MED RES, Ridgeway, London, England State Univ Ghent, Virol Lab, Fac Med Vet, Salisburylaan 133, Merelbeke, Belgium ***Article 21 Total Cites: 14 Article Title: Detection of human influenza A (H1N1) and B strains with reduced sensitivity to neuraminidase inhibitors Authors: Escuret, V, Frobert, E, Bouscambert-duchamp, M, Sabatier, M, Grog, I, Valette, M, Lina, B, Morfin, F, Ferraris, O Journal: JOURNAL OF CLINICAL VIROLOGY Volume: 41 Page: 25-28 Year: 2008 Addresses: UNIV LYON 1, CNRS, FRE 3011, Lyon, France Ctr Biol Est, Hospices Civils Lyon, CNR Virus Influenza France Sud, Bron, France OpenRome, GROG, Paris, France Univ Lyon 1, CNRS, FRE 3011, 7 Rue Guillaume Paradin, Lyon, France ***Article 22 Total Cites: 12 Article Title: Dose-dependent antibody response to influenza H1N1 vaccine component in elderly nursing home patients Authors: Remarque, EJ, de Jong, JMA, van der Klis, RJ, Masurel, N, Lighthart, GJ Journal: EXPERIMENTAL GERONTOLOGY Volume: 34 Page: 109-115 Year: 1999 Addresses: LEIDEN UNIV, Med Ctr, Sect Gerontol, Dept Gen Internal Med, Leiden, Netherlands Dutch Council Resp Viruses Particular Influenza, Rotterdam, Netherlands Leiden Univ, Med Ctr, Sect Gerontol, Dept Gen Internal Med, Leiden, Netherlands ***Article 23 Total Cites: 12 Article Title: Investigations of the efficacy of European H1N1- and H3N2-based swine influenza vaccines against the novel H1N2 subtype Authors: Van Reeth, K, Van Gucht, S, Pensaert, M Journal: VETERINARY RECORD Volume: 153 Page: 40069 Year: 2003 Addresses: GHENT UNIV, Fac Med Vet, Virol Lab, Merelbeke, Belgium State Univ Ghent, Fac Med Vet, Virol Lab, Salisburylaan 133, Merelbeke, Belgium ***Article 24 Total Cites: 11 Article Title: Infection of human airway epithelia with H1N1, H2N2, and H3N2 influenza A virus strains Authors: Slepushkin, VA, Staber, PD, Wang, GS, Mccray, PB, Davidson, BL Journal: MOLECULAR THERAPY Volume: 3 Page: 395-402 Year: 2001 Addresses: UNIV IOWA, Coll Med, Dept Internal Med, Iowa City, IA, USA UNIV IOWA, Coll Med, Dept Pediat, Iowa City, IA, USA UNIV IOWA, Coll Med, Dept Physiol Biophys, Iowa City, IA, USA UNIV IOWA, Coll Med, Dept Neurol, Iowa City, IA, USA UNIV IOWA, Coll Med, Program Gene Therapy, Iowa City, IA, USA Univ Iowa, Coll Med, Dept Internal Med, Iowa City, IA, USA ***Article 25 Total Cites: 10 Article Title: Antigenic and genetic characterization of 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来自: Department of Computer Science(Princeton University) Two Princeton Papers Recognized as ACM SIGPLAN Research Highlights October 20, 2008 In September 2008, ACM SIGPLAN , the ACM chapter dedicated to programming languages and compilers, nominated five research papers for consideration as research highlights to appear in Communications of the ACM. These five papers were selected from amongst all papers appearing at the top programming language and compilers conferences over the past 3 years. The selection committee was composed of the current and past ACM SIGPLAN chairs and the program chairs of the top SIGPLAN conferences. Remarkably, two of the five papers were from the Princeton computer science department: The next 700 data description languages appeared at POPL 06 and was co-authored by Kathleen Fisher (ATT Research), Yitzhak Mandelbaum, and David Walker. It formed the centerpiece of Yitzhak Mandelbaum's 2007 Princeton Ph.D. thesis. Yitzhak has since been hired by ATT research and continues his work on programming languages for data processing at ATT. Fault-Tolerant Typed Assembly Language appeared at PLDI 07 and was co-authored by Frances Perry, Lester Mackey, George A. Reis, Jay Ligatti, David I. August, and David Walker. The theoretical components of this paper formed the core of Frances Perry's 2008 Ph.D. thesis, while the implementation components were analyzed in George A. Reis' 2008 Ph.D. thesis. Both Frances and George are continuing their research after graduation at Google. Lester Mackey, an exceptional undergraduate from Princeton, is now in graduate school at Berkeley and Jay Ligatti, another former Princeton Ph.D., is now faculty at the University of South Florida. The next 700 data description languages Fault-Tolerant Typed Assembly Language