青蒿素的研究充分体现了当时全国一盘棋,大会战的特色。单纯的归功于某一个或者某几个人是不合适的。 老人们经常回忆起当年搞青蒿素的情形,基本上半个中国的力量都动用了。 听中药所的同行说过一些情况,当时屠教授的一些研究不是她完成的——她也没这个能力完成,是所长书记出面协调,请动某些大佬搞的,中药所加实验药厂为了青蒿素搞攻关会战,人人参与。 结果,最后,光荣属于一个人。屠做人上也不是没有缺陷,据说青蒿素被她视为禁脔,不许别人研究。不说国内其他单位,就是本单位对她不满的人也很多。 她评院士,评过两次,每次消息传来,老人们都会说,她得罪的人太多,不可能评上。果然! 评院士不是评水平,而是“”评得罪的人多少”。 你也承认屠教授没评上院士,不是因为她的贡献和水平,而是得罪了你们这帮人。 换句话,如果她把成就拱手相让,那么早就是院士了。什么逻辑! 她曾几次获院士提名 默默无闻多年后得到这么多关注,是“时来运转”吗?非也。 青蒿素类抗疟药是中国唯一被世界承认的原创新药。 当年青蒿素类抗疟药最主要的一群发现者,如今无一人做大官,无一人成富翁,无一人当院士。 屠呦呦教授也曾经几次被提名院士,但始终没有当选。 不过为“五二三”付出的心血,她始终无怨无悔。 http://blog.sina.com.cn/s/blog_65674ed00100i3k1.html Artemisia annua L and Artemisinin Medicines – A Scientific White Paper in Anti-Malaria History 《青蒿及青蒿素类药物》 - 一本抗疟史上的科技白皮书 - Artemisinin (青蒿素)博客 Artemisia annua L and Artemisinin Medicines authored by Professor You You Tu and published by China Chemical Industry Press records the details of how Artemisinin ( 青蒿素 pronounced as Qinghaosu in Chinese) – a potent anti-malaria compound was discovered by professor Tu in 1972 and a series of medicines derived from Artemisinin had beendeveloped by Professor Tu’s team and other scientists in China since its discovery. The book, based on sound scientific evidence, tells the world a true, yet mystery discovery history and highlights the successful outcomes of exploring ancient Traditional Chinese Medicine legacy through wisdom and hard workcontributed bycontemporary Chinese pharmaceutical scientists. The book covers wide range of scientific information, including Botany, Phytochemistry, Synthetic Chemistry, Analytical Chemistry around Artemisia annua L and Artemisinin Medicines as well as detailed data package generated during the course of new drug development. Professor Tu was the first scientist who established that a mixture extractedfrom Artemisia annua L leave byher unique isolation technique provided an effective therapy to animal models contrasted with multi-drug resistant strains of falciparum malaria. She then successfully purified artemisinin, a potent compound from the extracts in 1972. In 1986, based on her findings, she and her team launched Artemisinin as an innovative anti-malaria medicine in China after a thorough and lengthy development process. Late in 1992, she developed and launched another potent medicine Dihydroartemisinin, an Artemisinin derivative in the simplest format but yet the most effective compound among Artemisinin derivatives. Professor Tu’s achievement is well recognized both nationally and internationally. Recently, a Special Issue "Artemisinin (Qinghaosu): Commemorative Issue in Honor of Professor Youyou Tu on the Occasion of her 80th Anniversary" was published by Journal Molecules in which a number of top researchers in the fields offered their papers. It’s worth to comment that without Professor Tu’s breakthrough discovery, Human beings as a whole would have lost our battles against malaria, especially the multi-drug resistant falciparum malaria. Her achievement deserves more and much distinguishedinternational awards. Professor Tu is currently a professor and director of Qinghaosu (Artemisinin) Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical sciences. She also serves as a fellow of China Association of Invention. 《青蒿及青蒿素类药物》由屠呦呦教授编著,中国化工出版社出版,详细记录了屠教授于 1972 年发现青蒿素的经过以及她的团队和其他中国科学家在她发现青蒿素以后所做的工作。 本书以大量的科学证据告诉了世界一段真实而神奇的历史 - 一个用中国药物科学家的智慧和努力成功开拓中华医学遗产的范例。本书覆盖了大量的资料,包括围绕植物青蒿及青蒿类药物的植物学、植物化学、合成化学、分析化学资料以及新药开发过程中大量的研究数据。 屠教授是首位发现青蒿(黄花蒿)提取物有强抗疟活性的科学家。又是她于 1972 年首先分离出有效单体 - 青蒿素。 1986 年,根据她的发现和深入开发,她和她的团队首先将青蒿素作为新药在中国上市。 1992 年,她和她的团队又将另一新药 - 双氢青蒿素,一个结构最简单但最有效的青蒿素衍生物在中国上市。 屠教授的贡献被中国及国际社会公认。最近 , 《分子学杂志》为祝贺她的贡献,在她 80 岁生日时出版了《青蒿素专辑》。许多该领域的顶尖专家为专辑供稿。 值得一提的是, 如果没有屠教授突破性发现,全人类将惨败于抗疟战场。她的成就值得更多、更高的国际嘉奖。 屠教授目前是中国中医科学院中药研究所终身研究员,青蒿素研究中心主任及中国发明协会理事 。 青蒿素的故事,考验和教育了中国科学家 http://blog.sciencenet.cn/home.php?mod=spaceuid=280034do=blogid=486631