科学网

 找回密码
  注册
科学网 标签 Ash

tag 标签: Ash

相关帖子

版块 作者 回复/查看 最后发表

没有相关内容

相关日志

美国血液学年会见闻
qianggong 2015-12-12 07:11
· 检测 NK 细胞 killing activity 用 chromium-51release assay ( Ohio Stat Univ ) · AML : 克隆数越多预后越差; NPM1 突变可作为预后指标( Yale ) · B 细胞发育与 VDJ 重排: HPC- LPC - D/J 重排 - Pro-B - V/DJ 重排 -Pre-B - 轻链重排 - Naïve B (t-gen) · 相比于 ABC-DLBCL , GNA13 通路变异在 GCB-DLBCL 中更显著, P2RY8,GNA13 和 ARHGEF1 都有显著差异 · 斯坦福大学研究组开发的 CAPP-Seq 可用于检测外周血 ctDNA ,通过数学建模甚至可以估算克隆大小;数学模型包含淋巴瘤细胞生长速度(分裂速度 – 死亡速度)和 ctDNA 增长速度( ctDNA 生成 – ctDNA 降解) · 对 2000 病例调查显示, MyeloidNeoplasm 中有高频 DDX41 突变,且在亚洲人群中频率更好(亚洲: 4.1% ;高加索: 1.5% ) · Mir-155 靶基因: CEBP-beta, SOCS, SHIP-1, Jarid2,PU.1 · MYD88 和 CD79B 激活突变可作为 ABC-DLBCL 对 ibrutinib 抗性的预后指标( Abstract#2759 ) · Flow cytometry 结果显示 PTCL-NOS 全部为 CD8 阴性,其中一半为 CD4 阳性; AITL 中 83% 为 CD4+CD8- , 11% 为 CD4-CD8+ , 6% 双阴性(是否是诊断问题?) · 来自 Pharmacyclics LLC 的 Ibrutinib 治疗病人靶向测序分析( Abstract#2642 )调查了 cooperativemutated genes , ABC-DLBCL 中比较显著的有 CD79B/MYD88, BCL6/MYD88,CCND3/CD79B, CCND3/CDKN2B, CCDN3/MYD88, CD79B/NOTCH1, BCL6/CD79B, CDKN2B/MYD88,CDKN2A/CDKN2B, BCL6/MLL2, CDKN2A/PIM1 · 调查 8334 正常人基因组作为对照,以解决 DLBCL 缺少 normal 的问题(假阳性率每 Mb 基因组区域 3 个)( Dana-Farber ) · STAT6 在滤泡性淋巴瘤( FL )突变率为 13% ,其中 D419 为其热点; D419 突变可提高 CD23 转录水平 · GATA-3 、 T-bet 和 Ki-67 表达水平可作为 PTCL-NOS 分类指标( #3889 ) · DLBCL 的 stroma cell 中可见 clonal 的 T 细胞受体 · 剪切体包含多个因子,这些因子的突变常常是互斥的 (mutuallyexclusive) ( Yoshida et al, Nature, 2011, 478:64-9 ) · 用 ATAC-seq 研究 enhancer 貌似不错,只需要很少的细胞数
个人分类: 内功|3981 次阅读|0 个评论
Umbrella of American paleobotany 101-Sidney Roy Ash(1928--)
livingfossil 2015-5-1 06:46
Story of Paleobotany Series (No.343) Umbrella of American paleobotany—101- Sidney Roy Ash (1928--) 美国资深古植物学家 — Sidney Roy Ash(1928--) American paleobotanist-- Sidney Roy Ash (1928--) 20 世纪 60 年代,美国古植物学家 Sidney Roy Ash (1928- -) 曾在英国雷丁大学 (The University of Reading) 师从英国皇家学会院士、著名古植物学家 Thomas Maxwell Harris 教授 ( 1903---1983) 。 1966 年, Sidney Roy Ash 获得博士学位回美国工作。所以, Sidney Roy Ash 不仅是“ Umbrella of American paleobotany” 中的一员,也是“ Seward umbrella of world paleobotany ”中的一员。 The portrait of Sidney Roy Ash (1928- -) cited from Lyons, Morey Wagner (1995) ∮1 教育背景 1951 : BA, Midland Lutheran College; 1957 : BA, University of New Mexico; 1961 : MA, University of New Mexico; 1966 : PhD, University of Reading, England. Sidney Roy Ash 在 The University of Reading 完成的博士学位论文题目是:“ The Upper Triassic Chinle flora of the south-western United States ”。相关信息如下: Personal author: Ash, Sidney R. (Sidney Roy), 1928- Title: The Upper TriassicChinle flora of the south-western United States. Publishing information: Reading, 1966. General note/s: Thesis (PhD.) -University of Reading, Department of Botany. Available to download from EThOS (registration required) Local note/s: EThOS persistent id:uk.bl.ethos.496632 Added corporate author: University of Reading. Department of Botany. Electronic access: Click here to login to EThOS to download this thesis. https://rdg.ent.sirsidynix.net.uk/client/en_GB/library/search/detailnonmodal/ent:$002f$002fSD_ILS$002f809$002fSD_ILS:809686/one?qu=Sidney+R.+Ashlm=EXCL_LR2 ∮ 2 研究领域 主要研究美国西南部晚三叠纪植物化石 ∮3 工作经历 1970--1997 年主要供职学术机构: Department of Geology, Weber State University, Ogden, Utah 84408 退休后供职于: Department of Earth Planetary Sciences , University of New Mexico , Albuquerque, NM, United States ∮4 部分论著 Sidney Roy Ash 部分论著目录: Ash, S. R. 1972. Plant megafossils ofthe Chinle Formation. In W. J. Breed and C. S. Breed , Investigations inthe Triassic Chinle Formation. Mus. Nor. Arizona Bull. 47: 23–43. Ash, S. R. Plant megafossils. In S. R.Ash , Geology, paleontology, and paleoecology of a Late Triassic lake,western New Mexico. Brigham Young Univ. Geol. Stud. 1978. 25(2): 23–42. Ash, S. R. 1985. First record of theGondwana plant Schizoneura (Equisetales) in the Upper Triassic of NorthAmerica, pp. 59–65. In R. Weber , 3rd Congreso Latinoamericano dePaleontologia, Simposio sobre floras del Triasico Tardio, su fitogeografia ypaleoecologia . Universidad Nacional Autonoma Mexico, Instituto Geologia,Memoria. Ash, S. R. 2005. A new Upper Triassicflora and associated invertebrate fossils from the basal beds of the ChinleFormation, near Cameron, Arizona. Paleobios. 25: 17–34. Ash, S. R. 2006. Chilbinia gen.nov., an archaic seed fern in the Late Triassic Chinle Formation of Arizona,USA. Palaeontology 49: 237–245. Ash, S. R. 2009. A Late Triassic floraand associated invertebrate fossils from the basal beds of the Chinle Formationin Dinnebito Wash, east-central Arizona, USA. Palaeontogr. ABT B. 283:1–37. Ash, S. R. 2010. Stop one: Summary ofthe Upper Triassic flora of the Newspaper Rock Bed and its paleoclimaticimplications, pp. 59–71. In A. Trendell , Paleosols and Soil SurfaceSystem Analogs. SEPM-NSF Research Conference and Workshop, Petrified ForestNational Park, Arizona, USA . Baylor University, Waco, TX. Ash, S. R. 2014. Contributions to the Upper Triassic Chinle Flora in the American Southwest. Palaeobiogeog. Palaeoenviron .DOI 10.1007/s12549-014-0150-3 ------------------------ 孙启高 2015 年 4 月 30 日整理 本期编目 古植物学的故事 343 期 Story of Paleobotany Series (No.343) Umbrella of American paleobotany—101- Sidney Roy Ash (1928--) 美国资深古植物学家 — Sidney Roy Ash(1928--) American palaeobotanist-- Sidney Roy Ash (1928--) http://blog.sciencenet.cn/blog-225931-886574.html 2015-5-1 06:46 ===================== 参见 : 古植物学的故事 228 期 Story of Palaeobotany Series (No.228) Umbrella of American palaeobotany--1: An unfinished list of American palaeobotanists http://blog.sciencenet.cn/blog-225931-826366.html 2014-9-10 05:45 古植物学的故事 240期 Story of Palaeobotany Series (No.240) Seward umbrella of world palaeobotany http://blog.sciencenet.cn/blog-225931-845010.html 2014-11-2100:13 英国古植物学名师 T. M. Harris教授] Story of Palaeobotany Series (88): An interesting palaeobotanical lineage in the UK (PartIII)-- Thomas Maxwell Harris (FRS, 1903---1983) http://blog.sciencenet.cn/blog-225931-399059.html http://www.sciencetimes.com.cn/blog/user_content.aspx?id=399059 发表于 2010-12-30 12:29:29 Lyons P. C., Morey E. D. Wagner R. H. (eds.), 1995. Historical Perspective of Early Twentieth Century Carboniferous Paleobotany in North America (W. C. Darrah volume), Geological Society of America Memoir 185,Boulder, Colorado. ======================================
个人分类: 古植物学的故事-Story of Palaeobotany Ser ...|3127 次阅读|0 个评论

Archiver|手机版|科学网 ( 京ICP备07017567号-12 )

GMT+8, 2024-4-27 00:41

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社

返回顶部