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[转载]利用Matlab中的fdatool设计滤波器(低通、高通、带通)
wxs4ever 2019-10-20 04:33
数字滤波器的设计是数字信号处理技术的一个核心问题,除了众多的滤波器设计函数之外,Signal Processing Toolbox还提供一个带交互式界面的滤波器设计工具—FDATool。用户可以通过对话框的方式给出滤波器设计要求,然后使用FDATool对滤波器进行直接设计。对于设计完成的滤波器,在FDATool中可以对其进行分析,绘制幅频曲线、相位响应、零极点图等,并且将设计结果保存到工作空间中,同时,也可将其保存为mat文件、文本文件,或者直接生成C语言的头文件等。 Simulink内启动方式: Signal ProcessingBlockset-Filtering-Filter Designs-Digital Filter Design。将模块拖入,然后双击便会出现FDATool设置界面。总体来说,这个工具应该是直观易用的,应该在掌握基础知识的基础上,配合帮助文档,才能很快的熟悉该工具。 本处链接: https://blog.csdn.net/Reason_Lee/article/details/80525292 ———————————————— FDATool工具的主界面(已配置好参数)如下所示: FDATOOL(Filter Design Analysis Tool)是MATLAB信号处理工具箱里专用的滤波器设计分析工具。 FDATOOL界面如图所示,总共分两大部分:一部分是Design Filter,在界面的下半部,用来设置滤波器的设计参数;另一部分则是特性区,在界面的上半部分,用来显示滤波器的各种特性。 Design Filter部分主要分为Response Type(滤波器类型)选项和Design Method(设计方法),其中Response Type选项包括Lowpass(低通)、Highpass(高通)、Bandpass(带通)、Bandstop(带阻)和特殊的FIR滤波器;Design Method包括IIR滤波器的Butterworth(巴特沃斯)法、Chebyshev type I(切比雪夫I型)法、Chebyshev type II(切比雪夫II型)法、Elliptic(椭圆滤波器)法和FIR滤波器的Equiripple法、Least-Squares(最小均方)法、Window(窗函数)法。 Filter Order(滤波器阶数)选项定义滤波器的阶数,包括Specify Order(指定阶数)和Minimum Order(最小阶数)。在Specify Order中填入所要设计的滤波器的阶数(对于n阶滤波器,Specify Order=n-1);如果选中Minimum Order选项选项,MATLAB则根据所选择的滤波器类型自动使用最小阶数。 Frenquency Specifications选项可以详细定义频带的各参数,包括采样频率Fs和频带的截止频率。它的具体选项种类由Filter Type选项和Design Method选项决定,例如Bandpass(带通)滤波器需要定义Fstop1(下阻带截止频率)、Fpass1(通带下限截止频率)、Fpass1(通带上限截止频率)、Fstop2(上阻带截止频率),而Lowpass(低通)滤波器只需要定义Fstop1、Fpass1。采用窗函数设计滤波器时,由于过渡带是由窗函数的类型和阶数所决定的,所以只需要定义通带截止频率,而不定义阻带参数。 Magnitude Specifications选项可以定义幅度值衰减的情况。例如,设计带通滤波器时,可以定义Wstop1(频率Fstop1处的幅值衰减)、Wpass(通带范围内的幅值衰减)、Wstop2(频率Fstop2处的幅值衰减)。当选取采用窗函数设计时,Window Specifications选项可定义,它包含了各种可选的窗函数。 ———————————————— 版权声明:本节为CSDN博主「yundanfengqing_nuc」的原创文章,遵循 CC 4.0 BY-SA 版权协议,转载请附上原文出处链接及本声明。 原文链接:https://blog.csdn.net/yundanfengqing_nuc/article/details/70510838 (一)设计一个低通滤波器 打开matlab,键入fdatool后,会弹出该工具的对话框。然后按照下图设置相关参数,参数列表中的Fs应该是采样频率,Fc是截止频率,即幅频特性曲线-3dB对应的频率。点击“Design Filter”后,幅频特性曲线会被更新。 然后切换到下面这个页面,点击“Realize Model”后,会进入simulink的页面。 点击simulink页面中的模型,就可以看到对应的z变换模型,如下图所示。 (二)设计一个高通滤波器 其设计过程与低通滤波器类似,不再赘述。 ———————————————— 版权声明:本节为CSDN博主「Ronnie_Hu」的原创文章,遵循 CC 4.0 BY-SA 版权协议,转载请附上原文出处链接及本声明。 原文链接: https://blog.csdn.net/Ronnie_Hu/article/details/79938333 (三)设计一个带通滤波器 现设计一带通Butterworth滤波器,滤除输入信号源为100Hz正弦波和一个随机噪声信号中的随机噪声。具体步骤如下: 1、打开FDATool的滤波器设计及分析界面,如上图所示。 2、在滤波器设计参数指定区域中,将滤波器(Filter Type)设置为带通(Bandpass);设计方法(Design Method)设置为IIR类中的Butterworth滤波器;滤波器阶数设置为2阶。 3、指定所需设计的滤波器的频率参数。首先,需要给出频率单位(Units),可以是模拟频率(包括Hz、kHz、MHz、GHz几种单位),采用这种方式给出频率指标需要给出采样频率Fs,本例中为2000Hz。 4、最后,需要指定滤波器允许的通带; 5、在完成以上设置后,点击Design Filter,将在FDATool界面上的“Magnitude Response”区域以图形的方式清楚的显示出用户所要求的滤波器的理想频响的性状,每个设计指标也在图中进行了清楚的标注。 6,设计一个包含100Hz正弦波和一个随机噪声的输入信号的simulink仿真模型,使用设计好的滤波器模块滤除其中一个输入信号,并用示波器观察滤波效果。 7、设置正弦波参数如下:幅度1,频率100Hz,采样时间1/2000秒,一帧256个采样值。 8、设置随机噪声信号参数如下:采样时间1/2000秒,一帧256个采样值。其余保持默认值。 9、设置向量示波器参数如下:勾选Display Properties下的Channel legend。 Simulink建模如下: 运行后观察示波器,得到下图结果,可以发现该滤波器较好的滤除了正弦信号中混杂的噪声。 ———————————————— 版权声明:本节为CSDN博主「Reason_Lee」的原创文章,遵循 CC 4.0 BY-SA 版权协议,转载请附上原文出处链接及本声明。 原文链接: https://blog.csdn.net/Reason_Lee/article/details/80525292
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[转载]【源码】便捷飞行器设计软件Aircraft Intuitive Design (AID) version 1.2.0.0
lcj2212916 2018-11-16 08:59
通过将用户友好交互的飞机建模与快速空气动力学分析相结合,本程序直观地描述了 各种设计参数如何影响飞机的飞行方式 。 By interfacing user-friendly aircraftmodeling with rapid aerodynamic analysis, this program visually depicts howvarious design parameters affect the way an airplane flies. MathWorks 网站上验证该代码的视频网址如下: A video demonstrating some of the code'scapabilities can be found on the MathWorks website at https://www.mathworks.com/videos/matlab-and-simulink-robotics-arena-building-interactive-design-tools-1509569729395.html. 除了在调整飞机模型时更新的内置线性稳定近似值之外,程序还支持与下列软件进行接口,以便进行更高级的分析: In addition to built-in, linearizedstability approximations that are updated every time the aircraft model isadjusted, the program interfaces with the following software for more advancedanalysis: 1. Digital DATCOM –U.S.Air Force 2. Tornado Vortex Lattice Method –Tomas Melin (KTH Royal Institute of Technology) 3. AVL (Athena Vortex LatticeMethod) – Mark Drela and Harold Youngren (MIT) 本代码还可以通过以下开源软件获得附加的其它功能: 1. DATCOM Plot InterpolationFunctions – Prof. Glenn Greiner and Lenny Gartenberg (ERAU, Daytona Beach, FL) 2. AVL Input/Output Functions –Joseph Moster (Mathworks File Exchange) 3. Datcomimport – MathWorksAerospace Toolbox – loads DATCOM for006.dat file 4. NACA456 – Ralph Carmichael(PDAS) – calculates NACA 6-series airfoil ordinates 工具箱插件下载地址: \0 http://page5.dfpan.com/fs/clcbj2c21e29f16c9e1/ 更多精彩文章请关注微信号: \0
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[转载]Design and development of CSP techniques for finding robust
lcj2212916 2018-8-30 17:03
Design and development of CSP techniques for finding robust solutions in job-shop scheduling problems with operations Master Thesis in Artificial Intelligence, Pattern Recognition and Digital Imaging September 2012 Supervised by: Dr. Miguel á. Salido Gregorio Dr. Federico Barber Sanchís Presented by: Joan Escamilla Fuster 下载地址: http://putpan.com/fs/3lc6j23217290162634/
801 次阅读|0 个评论
For memory of Dr. Offer Shai
DCC08 2016-7-16 04:18
I am terribly sorry to tell you that Offer has passed away tonight. ------- A tragic news i got in Berlin on july 14th. He said he would attend ADCP2016 if his health condition was good enough for a long journey. Wish he were there. I would say thanks to him for his kind talks, discussions, lectures and visits for adcp seminars and lectures.
2147 次阅读|0 个评论
Journal of Mountain Science Promotion Flyer Design
waterlilyqd 2015-7-12 15:10
Generally we commisioned professional art designer for journal promotion materials design. I designed two pages of flyer for our journal with microsoft publisher. This software provides many color pattens and background selections. It makes the design become simple. The follows are several designs I tried to do . The first two design are almost the same but only the background is different. In your mind which one is better? Or what are your suggestions? Design 1 Design 2 Design 3 中文版式
个人分类: JMS信息|2463 次阅读|0 个评论
竹盐与纳爱斯牙膏包装创新的对比分析——钱安明
热度 2 qiananming 2014-2-25 00:18
参考文献引用 钱安明,陆小彪,殷石.竹盐与纳爱斯牙膏包装创新的对比分析 .包装工程,2014,02:114-116+121. QIAN An-ming,LU Xiao-biao,YIN Shi.Comparative analysis of the bamboo salt with NICE toothpaste packaging innovation . Packaging Engineering,2014,02:114-116+121. 竹盐与纳爱斯牙膏包装创新的对比分析_钱安明_陆小彪_殷石.pdf 竹盐与纳爱斯牙膏包装创新的对比分析 钱安明 1,2 ,陆小彪 2 ,殷石 2 ( 1. 苏州大学 艺术学院,江苏 苏州 215123; 2. 安徽农业大学 轻纺工程与艺术学院,安徽 合肥 230036) 摘 要 : 目的 研究两种牙膏包装中的微创新和设计心理学。 方法 以竹盐和纳爱斯牙膏内包装的设计为例,基于两种牙膏产品的文化内涵、品牌定位、材料与技术的革新,围绕产品包装造型本体特性以及膏体外观所呈现的视觉性特点展开分析。 结果 两种牙膏盖的微创新及其包装细节都着重消费者在牙膏使用过程中的体验,纳爱斯牙膏的设计更合于大众使用心理和操作习惯。 结论 综合论证了创意思维和设计心理学在牙膏包装与创新设计实践中的应用意义。 关键词: 牙膏包装;包装创新; 牙膏盖;设计心理学 中图分类号 : TB472 文献标识码 : A 文章编号: 1001-3563 ( 2014 ) 02-0114-03 Comparative analysis of the bamboo salt with NICEtoothpaste packaging innovation QIAN An- ming1 , LUXiao-biao 2 , YIN Shi 2 ( 1. School of Art, Soochow University, Suzhou 215123,China; 2. College ofLight- textile Engineering and Art, Anhui Agricultural University, Hefei230036, China ) Abstract : Objective Study two kinds of toothpaste packagingmicro-innovation and design psychology. Methods Contrast Bamboo salt and NICE inner packaging design, for example,based on two kinds of toothpaste products, culture, brand positioning,materials and technology innovation, focusing on product characteristics andthe package body styling. Expand analysis on paste visual appearancecharacteristics presented. Results Twokinds of toothpaste cap micro-innovation and its packaging details are focusedconsumers experience , during use toothpaste, toothpaste NICE design is more fit for publicuse and operation of mental habits. Conclusion Comprehensive demonstrates the creative thinking and designpsychology in toothpaste packaging and innovative design application inpractice significance. Key words: toothpaste packaging; packaging innovations;toothpaste cap; design psychology 牙膏虽然是普通日用化学产品,其推广上市的过程与时尚工业中的服装、箱包、香水造势并无二致 。围绕牙膏产品的周边设计与研究包括平面视觉、包装工程与品牌营销。线上线下的工作也如此分工和具体展开。当企业的形象与品牌已确定,特定产品的品类形态也为大众所熟知,过分大胆的“创新” 反而干扰消费者的习性,挑战用户有关某种产品固定用法习惯的“创意”不仅极为有害,也是产生相反作用的蹩脚设计 。 作为快消品的牙膏是消费者不得不买但又并不十分在意其品质的一种生活必需品,消费者对于牙膏的品牌忠诚度并不高 ,消费者经常在一管牙膏用完之后购买另一种口味完全不同的新牙膏,而不是坚持一种牙膏长期使用。事实上,牙医也经常建议消费者定期更换牙刷并且交叉使用不同类型的牙膏。由此观之,牙膏产品的创新就显得十分必要,不仅要注重讲究视觉效果的外包装设计,内包装结构的贴心设计也是十分重要的举措。 1 以竹盐和纳爱斯为例 1.1 对比样本研究概述 家化、洗化类产品似乎离不开大众传媒打品牌,纳爱斯和竹盐也不例外。竹盐牙膏是韩国 LG 公司旗下的产品,纳爱斯是中国浙江的一家主打洗化产品的品牌公司,这些年异军突起,在宝洁、联合利华两大巨头的夹缝中顽强生存了下来。竹盐在韩国家喻户晓,但在中国市场上产品所占有的份额以及品牌知名度并不高。纳爱斯牙膏没有历史名声可以凭借,占领市场不是仅凭看不见摸不着的广告知名度,而是产品本身的设计赢得了消费者并创造了新的价值 。 1.2 竹盐牙膏的文化内涵 竹盐的特色之处在于商品名称,“竹筒里的盐” 通过内外包装的插画展现其独特的产品风貌。竹子在亚洲以及中华文化圈里都是高洁的象征,竹与盐的结合不会产生误解和歧义,内涵清晰、明确。《红楼梦》里写到过大户人家用炒过的青盐和茶水洁齿、漱口,盐和牙膏本来就有着莫大的关系。竹盐牙膏以盐为产品切入点,让消费者自然联想起洁净牙齿之物的历史、传统和文化。“每日之盐”也时时提醒人们在洗漱之间加强和加深对产品的认知和印象。 1.3 纳爱斯牙膏的重新定位 产品的差异性是消费者个性化消费的关键,纳爱斯的产品理念差异,使其创新设计出“维 C 营养牙膏”,显然在牙膏的功能诉求上有别于仅关注清洁、清凉的同类产品。缺少维生素 C ,牙齿牙龈容易出血,严重的还会得败血症,这似乎也是普通消费者在中小学时代就获知的生物学常识。“营养”二字让人在刷牙同时不禁莞尔,是否真有营养,老百姓大概也不会深究,毕竟这种漱口之后就吐掉的清洁产品能在短暂的时间里给牙齿牙龈补充什么营养?事实上这种补益的功效并不重要,重要的是“营养”这个与食物有关的词汇与牙膏相结合,使得民众剥离了原先将牙膏当药品的旧观念,消费体验也就更加良好,实际使用的心理感觉就转变为每天与食品接触而不是和药物打交道 ,人们对日常日用化学品的恐惧感也就大为降低。 2 牙膏膏体创新的设计思维 2.1 围绕 产品本体展开设计 牙膏的主要作用就是清洁和美白牙齿,单从这一点上考虑具有有效配方的类似药膏的白色膏体是最适当的“诚实”产品设计。可是消费者对于牙膏的态度并没有上升到药物的理性高度,传统的白色、透明的绿色以及彩条牙膏膏体已经很常见。牙膏配方的改变不仅不容易被消费者发现,还会带来很大的新产品推广风险。产品在包装造型上的细节改变,相比之下简单却有效的多。过分朴素甚至类似药品的产品包装并不适合每天一两次接触牙膏的消费者的使用心理。 2.2 牙膏膏体的视觉性设计 纳爱斯牙膏全透明的管体突破了“闷葫芦”的传统,消费者不仅可以直观的欣赏到透明、诱人的水果色牙膏膏体,更可以一手掌握牙膏的使用状况——牙膏的使用进度在使用者的视觉掌控之中。“明白消费”的使用过程让用户感受到了牙膏膏体本体功能之外的精神享受,这是更高层次的用户产品体验设计。竹盐牙膏的膏体也和纳爱斯一样,注重个性。淡紫色半透明的竹盐牙膏给人以薰衣草的视觉观感,人们在使用过程中自然也会感觉到满口芬芳。 2.3 牙膏使用中的心理学体验 牙膏的膏体与人们日常的食物相关联是有效的创新设计之路。牙膏本身的化学成分不做任何改变的前提之下,仅仅在产品呈现方式上有些许改变也可以唤起消费者的全新体验。膏体的成分、成色以及最终呈现在世人眼前的稳定状态是化学家们的“设计”。产品走向市场过程中的包装才是设计师的工作重心,包装二字本身也可以被看作是设计的代名词。因此在消费对普通牙膏的色彩已厌倦的前提下,竹盐牙膏的淡紫色,纳爱斯的橙色牙膏还是让人有意外的惊喜。不同膏体色彩的技术实现应该不是太大的难题,之所以大多数厂家坚持本色产品不动摇,个中缘由一则是对创新的惰性,另一则是思维上的惯性。 3 牙膏内包装结构的创新思路 3.1 材料与技术影响下的新设计 牙膏管的材料选择使得灌装在其中的产品带给人不同的观感和消费体验 。早期的牙膏皮通常由柔软的轻质金属充当 。在铝材大行其道之前,牙膏管主要由锡皮甚至铅皮组成。铅金属有毒自然要被弃用,即使无毒的锡和铝也会使洁白的牙膏染上一层金属色的银灰,让人产生不想取之入口的厌恶情绪。无毒的塑料管是非常适当的牙膏管材,但塑料立即回弹的特性也不十分有利于“挤”牙膏 。如今大多数厂家都采用铝基材料与塑胶复合 ,复合材料兼具两种材料的特性,塑料表面易于彩印,帮助其实现广告价值。不过合成材料的价格稍贵,加之金属的存在也就不可能实现透明,化学家精心设计的美丽的牙膏膏体色彩要在挤出之后才能被看见。 3.2 基于 “格式塔”心理的分析 人们在牙膏的使用中,直接与产品内包装发生关系,刷牙前的准备工作首先就是要拧开牙膏管上的牙膏盖。大多数人都有过拧不开盖子或者不小心将小小的盖子掉到脏兮兮的地板上的闹心经历。甚至于手一滑,牙膏盖子直接掉进洗脸池的下水管内,让人懊恼不已。牙膏是通过挤压的方式将膏体附着在牙刷上的,牙膏的保护性软包装结构开口很小,即便没有牙膏盖的保护,膏体也不会迅速干结。可是牙膏毕竟是要入口的口中之物,使用之前的膏体敞口放置总不会让人放心,加上人们天生的“格式塔” (Gestalt) 心理作用,丢失了牙膏盖的牙膏总是不完美的,不完美的产品保护结构会让人纠结与不安。 3.3 牙膏盖的微创新 设计思维的自由有时只是一定范围内的无拘无束,在单支牙膏的重量、体积大小相对固定的市场规则中,微创新同样能够产生令人眼前一亮的亮点设计。竹盐和纳爱斯牙膏内包装结构的微创新,首先体现在小小的牙膏盖上,他们共同的设计策略就是增大了盖子的体积,这种创新设计解决了以往牙膏使用中容易让人烦恼的问题。 为消费者设计就要允许用户犯错,而不是强求使用者迁就设计的缺陷。唐纳德·诺曼( Donald Arthur Norman )在其著作《设计心理学》( The Design of Everyday Things )中如是说。大盖子的设计从根本上解决了这一难题,虽然小心使用产品的人会注意保护像牙膏盖这样的小配件不至于使之丢失,可是晨起的人们在睡意朦胧的生活中都要处处小心,工作的压力就太大了。 3.4 两种盖子设计的细节对比 仔细对比两种牙膏盖的细节差异。纳爱斯牙膏盖借用了洗面奶的盖子设计,底面更平,竖着放置时更为平稳,竹盐稍小的盖子显然在竖放时不十分妥当。纳爱斯牙膏的盖子的拧开方式并无“创新”,是传统的旋转打开。竹盐的牙膏盖是一种运用材料特性的“弹性设计” ,利用塑料本身的特点,使用手指的压力而不必借助螺纹将盖子卡在管口或拔出来。这项设计让人惊异,但不是惊喜。笔者第一次不知道如何打开这个盖子,下一次基于以往的使用习惯,旋转几次无果之后才想起来正确的开启方式。消费者在日常的个人护理过程中遭遇“输错密码”的尴尬,产品使用的特殊“乐趣”并不会让大多数消费者欣然接受。 4 结语 产品的设计包括产品的本体设计和包装设计,牙膏包装包括兼具保护性的内包装结构和注重视觉效果的广告营销用的外包装。本体设计就比如牙膏的膏体设计,但为保护产品而存在的内外包装有其独立存在的设计价值。事实上产品的包装结构的成败,关系到消费者的产品使用体验。从人机工程学和“以消费者为中心”的设计原则去审视牙膏盖的改进,不应该违背消费者使用习惯追求差异性的概念,应藉由设计促使人们迈进节约、绿色和生态的理想生活之路。 参考文献 潜铁宇 , 陶洁 , 裘以斌 . 包装设计的创新 . 包装工程 , 2007(10):75-77. QIANTie-yu,TAO Jie,QIU Yi-bin. Packaging DesignInnovation . Packaging Engineering, 2007 (10) :75-77. 陆小彪 , 钱安明 . 设计思维 . 合肥 : 合肥工业大学出版社 , 2006. LU Xiao-biao,QianAn-ming. Design Thinking . Hefei: HefeiUniversity of Technology Press, 2006. 何佳 , 钱安明 , 殷石 , 等 . 广告设计 . 合肥 : 合肥工业大学出版社 , 2009. HE Jia,QIANAn-ming, YIN Shi. Advertising Design . Hefei: HeFei University of Technology Press, 2009. 陈香 , 王雪莹 . 产品设计的价值创新与战略制定 . 包装工程 , 2012(20):106-109. CHEN Xiang,WANG Xue-ying. Value of the Product DesignInnovation and Strategy Formulation . . Packaging Engineering, 2012 (20):106-109, 殷石 . 食品包装中图形的设计心理沟通 . 长春理工大学学报 , 2011(5):100-101. YIN Shi. Psychological Communication in Food PackagingGraphic Design . Journal of Changchun University of Science andTechnology, 2011 (5) :100-101. 赵鹏 , 曹乐 . 牙膏包装发展探讨 . 包装工程 , 2010(4):117-119. ZHAOPeng, CAO Le. Explore the Toothpaste PackagingDevelopment . Packaging Engineering, 2010 (4) :117-119. 亦是园 . 牙膏包装的革命性变化 . 上海包装 , 1996(3):33. YI Shi-yuan. The Toothpaste Packaging Revolutionary Change . Shanghai Packaging, 1996 (3): 33. 张琰 , 黄伟 . 单支牙膏包装保护能力的测试及探讨 . 口腔护理用品工业 , 2012(4):20-22. ZHANGYan, HUANG Wei. Explore and Test Single ToothpastePackaging ability of protect . Toothpaste Industry, 2012 (4) :20-22. 陈玉明 , 陈学康 . 铝塑复合软管牙膏包装若干问题的分析与探讨 . 口腔护理用品工业 , 2010(6):28-31. CHEN Yu-Ming,CHEN Xue-kang. Analysis and Discussion about Plastic Composite Hose Toothpaste Packaging . Toothpaste Industry, 2010 (6) :28-31. 钱安明 , 李东 , 张琛 , 等 . 工业产品造型设计 . 合肥 : 合肥工业大学出版社 , 2009. QIAN An-ming, LI Dong, ZHANG Chen, Industrial Product Form Design . Hefei:HeFei University of Technology Press, 2009. 收稿日期: 2013-03-12 基金项目:安徽省教育厅人文社会科学研究项目( SK2012B168 );安徽 省教育厅高校省级优秀青年人才基金一般项目 ( 2012SQRW041 );安徽农业大学繁荣发展哲学社会科学基金重点立项项目( 2011zxshzd1) Fund: ; Education Department of Anhui Provincial Humanities andsocial science research projects (SK2012B168);Education Department of AnhuiProvincial Higher young talents Fund Project (2012SQRW041); Prosperity anddevelopment of philosophy and social science fund project in Anhui AgriculturalUniversity(2011zxshzd1) 作者简介:钱安明( 1980- ),男,安徽人,苏州大学艺术学院博士生。安徽农业大学轻纺工程与艺术学院讲师。主要研究艺术设计思维方法与设计心理学。 Author: QIAN An-ming (1980 -), Male, Doctor, Lecturer. Soochow University. College of Textile Engineering and Arts, AnhuiAgricultural University. Hefei 230036, China. E-mail: qiananming@163.com
个人分类: design thinking|6700 次阅读|8 个评论
LifestyleDesign---Day 4
dymseu 2014-2-18 10:48
2/17/2014 Monday 9:44:22 PM Lifestyle Design---Day Four Mylife in the United States Welcome to day 4! John10:10-11 The thief does not come except to steal and kill and destroy; Ihave come that they may have life and may have it abundantly. I am the goodShepherd; the good Shepherd lays down His life for the sheep. The Gospel of John is a book of life, and the life is simply the Triune God Himself.Life always has an issue. All Living things bring forth fruit. Surely the divinelife will have a divine result. Lord Jesus, did I bear a spiritual fruit today?May Your life gain in me more and more each day, Lord Jesus. Nearly spend the whole day finishing the assignment of structural dynamics, a tough task! Anyhow, thanks Lord, He leads me through. Read a wonderful article this evening, just think about the following statements: “The average person, in as little as three to five years, can become recognized as aworld-class expert in a topic of his or her choice just by focusing on the subject for one hour a day.” The Productivity Handbook, Donald E. Wetmore. Sound a little far-fetched, right?But we always underestimate the effect of small steps, such as an hour a day,since we fail to see the big picture, the cumulative effect. An hour a day, is 350 hours a year. Surely an hour won’t make one an expert in anything, but anhour for a year will make a difference. As I read this, I am relating the statement to my future challenge, the rest of mylife. This is Day 4 of my commitment to post to the blog in English. Actually, the real “challenge” to myself is not somuch in the “blogging” as it is in the “Communicating.” I want to be competent in academic knowledgeand English communication. I should be seeing or feeling a sense of momentum bynow in my English. I have spent far morethan an hour a day on English. So after 30days or 365 days, am I picking up skill in my English? Can I see expertise as a counselor in myfuture? Yes or no? Up to now, I have just been winging it one day at a time. Sometimes I sit down with a vague notion of what I plan to write about, and sometimes I wondering around, should I first learnt how to write first, maybe start with somereading? But knowing and doing are two different things. I am having to learn to just “go for it,” to write anything just come to my mind, not write like a celebrated writer at the keyboard, maybe someday ;-). Just start with a few sentences, think about it, backspace, rewrite, read again,backspace, and revise, and so on. I really enjoy the writing process… 6 Simple Steps to Strategic Innovative Thinking:
个人分类: My Life in the United States|2461 次阅读|0 个评论
Lifestyle Design---Day 3
dymseu 2014-2-17 11:40
2/16/2014 Sunday 10:41:25 PM Lifestyle Design---Day Three My life in the United States “I’ve found that small wins, smallprojects, small differences often make huge differences.” – Rosabeth Moss Kanter Now comes the third day, small wins, well done! Try to hang on and I already see the differences! Today is Lord’s Day. I am not fully enjoyed in the gathering, may Lord forgive me. The past week is totally busy, and my daily schedule was thrown out…Many things were distracting me from Life. “That He would grant you, according to theriches of His glory, to be strengthened with power through His Spirit into theinner man,” (Ephesians 3:16) The coming week will still remain challenge. May Lord grant me His daily grace! Lord Jesus, at the end of theweek, I still turn to You, and I consecrate the coming week to You, Lord Jesus,the week is Yours, Lord You lead me walk in the path of life, no panic, nocomplain, no excuse, no delay, no negative thought. Besides, finishing the daily schedule, four major tasks in the following week is: Revise the draft paper for adviser toreview---due on Friday; Discuss the project topic with group member----dueon Tuesday; Complete the assignments of three coursesand review structural dynamics and soil engineering, make up quite a lot ofleeway, other you’ll fall behind-----Saturday Start the first road test practice with David, at least two hours! Come on, the test is inthe next week. Getting results in today’s landscape is noteasy, and sometimes may tough. The worldchanges faster than we can keep up. Evenworsen is that we don’t always have the best practices for focus, managing ourtime, managing our energy, or even our personal productivity. Matt Cutts, asoftware engineer in Google, may give you some assistance with how to manageyour life more efficient. http://www.ted.com/talks/matt_cutts_try_something_new_for_30_days.html Also, in the book, Unlimited Power: The New Science of Personal Achievement, TonyRobbins shares the keys to getting whatever you want, by asking moreeffectively. According to Tony Robbins here are the steps get whatever youwant: Ask specifically Ask someone who can help you Create value for the person you’re asking Ask with focused, congruent belief Ask until you get what you want
个人分类: My Life in the United States|1431 次阅读|0 个评论
Lifestyle Design-----Day 1
热度 1 dymseu 2014-2-15 12:57
My life in the United States 2/14/2014 Friday 11:55:21 PM New Year, new atmosphere, new goals! Come on man! “So then if anyone is in Christ, he is anew creation. The old things have passed away; behold, they have become new.” (Corinthians5:17) Here we are at the beginning of a new year.Another opportunity to look backwards and learn, another chance to look forward and stretch. “I do not account of myself to have laidhold; but one thing I do: Forgetting the things which are behind and stretchingforward to the things which are before” (Philippians 3:13) Time was cracking on, seven months had gone, since I first arrived in the United States on August, 20th ,2013. One of the most important things I learned is that if you want to survivehere, language is the first obstacle you have to overcome. The truth is my English hasn’t been greatly improved in the last months. Pretty rubbish at the beginning, somewhat frustrating… “And looking upon them, Jesus said to them,With men this is impossible, but with God all things are possible.” (Matthew19:26) So, it is never too late to clear up thepast and begin resolution! Good language environment, learning methodand enough time absolutely count, but, my experience tells, practice, eventually,makes perfect. My challenge in this following days is—youguessed it—to be fluent in English. Start from now, practice in trifles and details,read extensively, speak and read more and grasp language rules of English proficiently and even blog in English, and that’s my first English blog! For the world, I am determined to complete the thing. You’ll hear more about it as I see the end in sight. Good nigth, tomorrow is another day ! I'm looking forward to it !
个人分类: My Life in the United States|1783 次阅读|2 个评论
时尚之外的服装设计反思
qiananming 2014-1-23 14:09
引用本论文: 钱安明,吴蓉.时尚之外的服装设计反思 .安徽农业大学学报:社会科学版,2010(1):132-135. 时尚之外的服装设计反思 钱安明 , ,吴 蓉 2 ( 1. 苏州大学 艺术学院,江苏 苏州 215123 ) ( 2. 安徽农业大学 轻纺工程与艺术学院 ,安徽 合肥 230036 ) 摘要: “衣、食、住、行”之中所述及到的服装的重要性再怎么强调也不为过。然而服装设计所要设计的却不是一般意义上的服装,更多的工作却是非同寻常的潮流创造——在英文当中的服装设计就是时尚设计。基于服装设计在实际教学中的困惑,在此阐述了一些方向性的思考,并作出初步的结论,即当代的服装教育体系应着眼于产业的发展要求。 关键词 : 服装设计;教学思考;时尚设计;服装产业 中图分类号:TS41文献标识码:A 文章编号:1009-2463(2010)01-0132-04 Reflection of the Designing in Costumes outside Fashion QIAN An-ming 1 , 2 , WU Rong 2 ( 1. School of Art of Soochow University, Suzhou, 215123,Jiangsu ) (2. Collegeof Light- textile Engineering and Art,Anhui AgricultureUniversity, Hefei,230036, Anhui) Abstract: “The basic necessities of life” arereferred to the importance of clothing no matter how much it is be overstated.However, costume design by designer do not want a general sense on clothes,more times is actually the unusual trend of creating - in English dressdesigning is the fashion design. Based on the actual teaching costume design atthe confusion, elaborated some directive ponder,and make a preliminary conclusion thatthe educational system of contemporary apparel industry should focus on therequirements of the development. Keywords: costumes design; reflection; fashion design; apparel industry “衣、食、住、行”,在国人的语言里,衣服的地位是高过“天” 的。事实也的确如此,除了在极为艰难的战争年代,人们为了备战而不得不节衣缩食之外,平常的日子里,一日三餐之余总会想着去装扮自己的。服饰的社会属性应该源于个体的共通心理,这或许也正是服装虽然作为产品,却从来都不只遵循“功能性”的评判标准,甚至服装的“原始功能性” 总是有意无意的就被时尚界专家甚至全体大众都忽视了。 一、服装之外的设计 服装是物,没错的。然而今天的消费者购买服装时往往并不只是看中了其物质属性,消费者消费的不是服装本身。他们,又或者说我们,购买的从来都不是“服装”。我们目迷五色在色彩斑斓的大小店铺里找寻的是一种符号——能够代言自己的个性的或大众的身份认同象征物。不是穿上奢侈品才算“炫耀性的消费” ,事实上任何“不穿寻常衣”的普罗大众追求的都是一种“炫耀性的自我”。从这个意义上出发,常年身着长衫或洗白的中山装的大学教授不但不是游离于时尚之外,而是更为张扬的个性的本质外化显现。 紧追 80 年代以来的西方社会由生产主导型社会( production-oriented society )向消费主导型社会 (consumption-oriented society) 的全面转变的大潮流,当代中国各阶层的不同层次的消费问题也越来越为业界和学界所关注,服装的消费问题是这其中最容易为人所注意的。今天“反潮流”、“无装饰”的所谓反流行的流行性话题不断地、反复的、换着法儿“推陈出新”的涌现出来——这就是流行,这就是“文明的轮回” 。 服装设计,在今天看来,或许早已脱离了功能性设计的本质。“设计就是创新,创造非凡是设计工作的全部意义之所在” 。宋代诗人陆游云:“汝果欲学诗,功夫在诗外。”国画大师齐白石老人也说过:“如果做画,功夫在画外。”服装设计的“教”和“学”的着力点都应部分在专业之外,至于我们应该着重关注的是哪些方面的内容,下文将从服装的溯源、时尚到平常的过程、单体服装设计与服装产业竞争力的相互关系等几方面展开思考。 二、服装实现的进程 爱美是人的天性,尤其以女孩子为甚。所以服装设计也是以女装为核心的。服装设计当然是以服装为主体,不过箱包、鞋帽作为服装的附属物通常也属于服装设计的范畴——这也是通常意义上的服饰的含义。 服装其实并不都是需要设计的,服装设计师设计的“作品”的创意立足点从通常意义上观照,应是非实用性的艺术化创造,即,表演性服装和高级时装。用做表演的服装主要包括戏剧舞台角色的“外包装”以及影视剧里略带夸张的服装设计;另一类就是我们所熟知的模特秀( show ),即模特在 T 形台上走猫步,穿着以“抢眼”为目的的具表演服性质的服装,很多时候大抵这些就是我们理解的“时”装了。高级时装设计所针对的对象是高收入人群,即所谓的“多数人向往,少数人拥有”一类。这里的“高级”并不一定是因为材料的高成本,“高”主要是高在由著名的时装设计师量体裁衣所定做的独一无二的个性化服装。也许这就是历史的反讽吧:曾几何时,我们每一位普通百姓都曾穿着“高级时装”、享受过“专属”裁缝的贴体服务——当然那是在我国市场化发育程度还远未成熟的年代。商品经济不繁荣,商店里无衣可选,人们不得不求助小作坊的手工制作。今天面对堆的满满的衣橱,真想要挑出一、两件手工缝制的服装却实非易事。 如今批量化大生产的服装从概念到真实的被穿在百姓身上,其过程又是怎样的呢? 服装,从学科的归属上来推导,是艺术(确切的说来应属实用艺术)。那么从一般艺术学的角度来看:最“前卫”的服装应该首先是存在于艺术家的想象之中,是观念中的服装,其表达方式是语言、是文字。接下来视觉艺术家会以可识别的图形图像将创新的设计思想展现出来。这两个阶段的“服装”其实都还只是无形的“纯艺术” ,既然不可触摸,自然只能归为只供欣赏的艺术范畴。只有设计师的介入,将思想变成图纸(不是绘画);工程师的加盟,将图纸变成样衣——服装才真正的被创造了出来。 再次重复我们的观点:普通的服装是不用设计的。正如农耕时代,人们都自建房,不需要建筑师一样。设计的出现是因为人们对“普通”的不满,更高层次的“美的自我包装”的心理追求。所以我们学习服装发展史就会发现:服装风格的每一次革新的直接动因几乎绝少是为了使穿着者感觉更加舒适,很多时候服装潮流已经被异化为“时尚至死” 的纯粹虚荣。如今许多大众的语言都日渐以娱乐性方式出现,并成为一种“新新文化”的精神。同样的,大众面对铺天盖地的时尚广告、潮流服装也逐渐丧失了自我……个性既已不存在,服装品味的引导权又回到了设计师的手中,当然这种权力的威力显现还在于传播媒体的推波助澜。 服装设计也可以说就是时装设计。不断追求新款的消费者左右着设计师,或“天才”的设计师创造了新风尚,引领着新潮流。一台时装 show 的少数几款会成为贵妇身上的时髦洋装,当这种时尚的样式为大多数人所接受,许多厂家可以通过流水线大批量的生产的时候——此时的产品已不再是时装而是成衣,也才是大众所理解的一般意义上的服装了。 设计师所做的工作不是做一件能够遮体的“布衣”,而是一件让穿着者从内心感到振奋的“华服”。从务虚的层面上阐述:服装设计的核心任务不是为了创造服装新产品,而在于呈现给世人引领时尚潮流的新风貌( new look )…… 三、创新服装的高度和基础 “大牌”的服装设计师着力点往往只在大的方向的把握上,并不拘泥于特定的单体服装设计上。作为时尚的引导者应注重以品牌服装的构建和服装品牌的管理——这是每一位刚入行的职业服装设计师的大方向。当然也不能忘了提高个人的实作技能及核心竞争力,毕竟不是每个服装设计师最终都能够成为服装管理者。 今天我们的服装设计教育的目标是为了培养未来一线的新锐设计师,然而课程中所选用的依然是只提供服装基础理论知识的一般性教科书,教师们讲述的也都还是基本的服装设计理念和一般服装设计流程,并不能为学生们展现可供深层次学习的学科框架和实践平台。 当然实际的教学过程却又是漫长的,实实在在、平平淡淡。古人的经典画论告诫我们:“从无法到有法,再从有法到无法,无法是为至法”。设计更是如此!年轻的学生上来就学大师任意挥洒“概念”时装效果图,结果却可能会离大师越来越远。学习是一个长期的“渐悟”过程,尽管我们都期待早一天“顿悟”,然而欲速而不达。时尚需要拥有一种敏锐的感觉,这种感觉却也是可以培养的。没有人是天才,只有学习才可以将人变为人才。 有学者撰文:中国这些年没能出现设计大师就是因为当代中国学生所不得不承受太重的历史负担……时尚人士就该高于现实生活一点,超脱尘世之外才能有创造性的发挥。诚然,这一观点有一定道理。饭都没法吃饱,偏要和别人学芭蕾,怕是站都站不稳的。我们当然不会板着面孔强行要求学生们都以振兴中国服装产业为己任,然而在现实的土壤里成长,到底不能只将设计当做个人美美的化妆品。 换个角度看,当代中国有很多有才华的青年设计师最终没有能够从事服装设计而转行其他,才使得中国服装业(尤其是服装前期概念设计这一部分)并没有随着中国经济发展而走到世界的前列。专业角色的转换要看个人的能力和个人的兴趣能否适应,我们更希望服装设计师能做好本职工作,即做好设计而不是把更多的精力放在服装之外。大环境的营造仍需时间,整个服装产业的发展需要专业人材来完善这个链条。若我们的青年服装设计师都不屑做具体的服装设计工作而改行做老板,何来源头创意? 四、服装教育体系的分合 服装设计作为一个专业应该是而且可以是自成体系的,然而在中国高校中服装设计的专业地位却十分尴尬。在纺织类院校中服装设计往往被当作是大纺织专业下的分支学科,而在某些仅设有艺术设计专业的院校,服装设计又被当作是艺术设计的专业方向之一。上世纪 70~80 年代,有些专家教授甚至认为服装设计应纳入工业设计的范畴,理由是服装也是需要工业化大生产的设计类型。 我们不妨将服装设计与工业设计进行比较。和中国的许多艺术设计专业方向相似,服装设计也包括强调艺术美学的服装设计专业和强调结构设计的服装工程专业。这和工业设计在中国的地位非常类似,工业设计的主要内容涉及产品的外观设计,强调产品的美学特性和使用上的便利性,这和机械设计专业涵盖的产品设计不同。工业设计公司的设计师的职位设置,通常也分为艺术设计和工程结构设计两大部分 。服装设计也是如此,非工程专业背景的服装设计师主要负责服装外观款式,其工作是设计服装的新概念,完成效果图和简明的款式图。结构设计、精确制图和打版等事务往往交由工程设计人员完成。 一个学科是否完善、是否科学并不是看这个学科是否包罗万象,而是看这个学科大的框架体系是否科学。现今的服装艺术设计和服装工程设计已共同构建了完整的服装设计系。其中服装表演、面料设计等都是在服装设计前期和后期提供延伸服务的相关专业。 服装设计(又或者说是时尚设计)需要服装设计师对时尚的感觉超越常人的敏锐,并能够对这一市场有很好地把握,同时通晓服装史和服装设计的实践技术和服装市场化运作的基本知识。高校里学习服装设计的优势就在于能够得到了多位老师的帮助,同时有机会与所就读学校的同学互相学习而共同进步。 “分久必合,合久必分”,三国演义里的开篇导言用在服装学科的发展上,尽管不很合适,却也在一定程度上反映了数十年来的服装学科发展态势。在今天新的历史条件下,笔者期待“大服装” 概念的整合,而不再是眼前的分野。《易经•系辞》曰:“形而上者谓之道,形而下者谓之器。”道不离器,犹影不离形……“是故形而上者谓之道,形而下者谓之器,化而裁之谓之变,推而行之谓之通,举而错(措)之天下之民,谓之事业”。没有服装设计和服装工程的截然分工,完全的服装设计教学体系建立的优势就将显现在:完成一项既定的任务,可以系统的进行活动组织、计划、安排,而决非如今的简单的项目分割、叠加。 结语 中国已经是世界上最大的服装制造大国,但还不是服装设计强国,很多时候我们所做的工作还只在低水平重复。“中国只有卖出八亿件衬衫才能进口一架空客 A380 ”的告诫依然在耳边回响,没有原创设计的服装产业发展很艰难。 中国服装业曾经是、现在是、将来还有可能是国家的经济支柱,然而我们希望的中国服装的命运应该与今日不同——我们希望我们出口的不只是廉价的代工( OEM )衣服,我们希望我们卖出去的每一件服装除了作为物质的产品之外还包括高附加价值的自主品牌。服装设计就是“新”服装设计,原创设计很重要。这条道路任重而道远,这需要我们一线的服装设计师、服装专业的教师和年轻的服装设计学生共同努力,我们期待我们的国家成为真正的服装大国的那一天的到来。 注释: 收稿时间: 2009-3-24 钱安明( 1980- ),男,汉族,安徽天长人,安徽农业大学讲师。苏州大学艺术学院博士生。 吴 蓉( 1979- ),女,汉族,安徽合肥人,安徽农业大学讲师。武汉理工大学硕士研究生。 俗语说:民以食为天。 这里所述及的“原始功能性”并非是原始人的服装的功能性,而是特指服装的防寒、保暖等基本的物质性功能。 炫耀性消费 (ConspicuousConsumption) ,通常指的是上层阶级所购买的物品的超出了其本身的实用性价值和生存所必需,实则是一种浪费性、奢侈性的非理性消费,其目的是向他人炫耀和展示自己的金钱财力或特殊的社会地位,以及这种地位所带来的荣耀、声望和名誉。索尔斯坦·魏伯伦(又译为:凡勃伦)于 1899 年出版了《有闲阶级论 —— 关于制度的经济研究》一书中首创了“炫耀性消费”这一名词。 语出诸葛铠先生服装研究专著《文明的轮回——中国服饰文化的历程》的书名。中国纺织出版社 2007 版。 所谓“纯艺术”大概算是中国特有的说法了,这种提法的由来是为了与“工艺美术”也就是现在的“艺术设计”相区分,主要指强调艺术家个性创造的绘画、雕塑等等。 “时尚至死”是本文作者仿照(美)尼尔 ・ 波兹曼《娱乐至死》的书名所生造出来的一个术语,呼应波兹曼书中所述及的有关“我们成了一个娱乐至死的物种”的论断。 “大服装”概念的引导者是东华大学博士生导师张渭源教授,其概念的缘由应受已故著名视觉艺术家陈逸飞的“大美术”的启发。两者相似之处都强调学科交叉和相关专业的融合。 参考文献: 陆小彪,钱安明 . 设计思维 . 合肥:合肥工业大学出版社, 2006. 钱安明 . 包豪斯对中国设计教育影响浅谈 .(2002-05-08). http://www.dolcn.com/d/digest/20020508000648.html 袁金龙,钱安明,程雅娟,等 . 服装画技法 . 合肥:合肥工业大学出版社, 2009. 袁金龙,钱安明,张刚,等 . 服装设计 . 合肥:合肥工业大学出版社, 2009. 张纪文,苗勇,钱安明 . 服装市场营销 . 合肥:合肥工业大学出版社, 2009. 张纪文,闫学玲,钱安明 . 服饰手工艺 . 合肥:合肥工业大学出版社, 2009. 张纪文,张翔,钱安明,等 . 服装表演组织与编导 . 合肥:合肥工业大学出版社, 2009. 时尚之外的服装设计反思.pdf
个人分类: fashion design|3798 次阅读|2 个评论
[转载]International Journal of Design 国际设计杂志简介
qiananming 2014-1-16 19:35
International Journal of Design ISSN: 1994-036X (online); 1991-3761 (print) The International Journal of Design is a peer-reviewed, open-access journal devoted to publishing research papers in all fields of design, including industrial design, visual communication design, interface design, animation and game design, architectural design, urban design, and other design related fields. It aims to provide an international forum for the exchange of ideas and findings from researchers across different cultures and encourages research on the impact of cultural factors on design theory and practice. It also seeks to promote the transfer of knowledge between professionals in academia and industry by emphasizing research in which results are of interest or applicable to design practices. Abstracting/Indexing: Science Citation Index Expanded ( SCI-E ), Social Science Citation Index ( SSCI ), Arts Humanities Citation Index ( AHCI ), Scopus, ProQuest ABI INFORM, ProQuest Design Applied Arts Index (DAAI), Ergonomics Abstracts, EBSCO Computers and Applied Sciences Database Archiving: Web Archives of The United States Library of Congress
个人分类: design|2199 次阅读|1 个评论
Introduction to the Filter Design and Analysis Tool (FDATool
xiaoxinghe 2013-9-23 09:27
Introduction to the Filter Design and Analysis Tool (FDATool) fdatool .pdf fdatool Open the Filter Design and Analysis Tool.pdf Using FDATool.pdf
个人分类: Filter technique|0 个评论
[转载]Building Bulletin 93: Acoustic design in schools
jerrycueb 2013-8-28 13:27
Archive - Building Bulletin 93: Acoustic design in schools This publication has been archived. The summary text below was correct when the item was first published. It has been made available for reference use but should not be considered to reflect current policy or guidance. PLEASE NOTE: The September 2012 update document below (Acoustic performance standards for the priority schools building programme) should be used in place of Section 1 of the Building Bulletin 93 as the acoustic performance standards for the Priority Schools Building Programme (PSBP). For the purposes of Building Regulations submissions, any variations from the existing BB93 should be taken as Alternative Performance Standards approved by the Education Funding Agency for this programme. The constructional standards for acoustics for new school buildings are required to be achieved under the Building Regulations. Unfortunately a large number of classrooms in the UK currently suffer from poor acoustics. This Building Bulletin guides architects, acousticians, building control officers and building services engineers through the process of the acoustic design of schools in the context of the various types of spaces and activities. It contains performance standards, acoustic principles, good design practice, calculation procedures, case studies on existing schools and an example submission to a Building Control Body. Includes: Specification of acoustic performance Noise control Insulation from external noise The design of rooms for speech The design of rooms for music Acoustic design and equipment for pupils with hearing requirements Case studies · Building Bulletin 93: Acoustic design in schools This document guides architects, acousticians, building control officers and building services engineers through the process of the acoustic design of schools in the context of the various types of spaces and activities. It contains performance standards, acoustic principles, good design practice, calculation procedures, case studies on existing schools and an example submission to a Building Control Body. Publication 27 February 2004 · Building Bulletin 101 - Ventilation of School Buildings This Building Bulletin provides the regulatory framework in support of the Building Regulations for the adequate provision of ventilation in schools. It deals with the design of school buildings to meet the ventilation requirements of both The School Premises Regulations and the Building Regulations Part F (Ventilation). Publication 05 July 2006 · Fire safety design guidance - Building Bulletin 100 Information about 'Building Bulletin 100 (BB100) - design for fire safety in schools', including an option to download the guidance. General article 26 April 2012 · Building Bulletin 100: Design for fire safety in schools This is a design guide which shows clearly how the requirements for life safety, contained in the Building Regulations, can be met in the design of a new school or an extension. It brings together guidance on how to make schools even safer places for children to be in, with guidance on how to protect the continuity of their education. Publication 29 September 2007 http://webarchive.nationalarchives.gov.uk/20130401151715/https://www.education.gov.uk/publications/standard/publicationDetail/Page1/BB93
个人分类: 文献备份|2404 次阅读|0 个评论
[转载]Rules of siRNA design for RNA interference (RNAi)
Huitian 2013-8-20 21:47
General Guidelines siRNA targeted sequence is usually 21 nt in length. Avoid regions within 50-100 bp of the start codon and the termination codon Avoid intron regions Avoid stretches of 4 or more bases such as AAAA, CCCC Avoid regions with GC content 30% or 60%. Avoid repeats and low complex sequence Avoid single nucleotide polymorphism (SNP) sites Perform BLAST homology search to avoid off-target effects on other genes or sequences Always design negative controls by scrambling targeted siRNA sequence. The control RNA should have the same length and nucleotide composition as the siRNA but have at least 4-5 bases mismatched to the siRNA. Make sure the scrambling will not create new homology to other genes. Tom Tuschl's rules Select targeted region from a given cDNA sequence beginning 50-100 nt downstream of start condon First search for 23-nt sequence motif AA(Nsub19). If no suitable sequence is found, then, Search for 23-nt sequence motif NA(Nsub21) and convert the 3' end of the sense siRNA to TT Or search for NAR(Nsub17)YNN Target sequence should have a GC content of around 50% A = Adenine; T = Thymine; R = Adenine or Guanine (Purines); Y = Thymine or Cytosine (Pyrimidines); N = Any. Rational siRNA design By experimentally analyzing the silencing efficiency of 180 siRNAs targeting the mRNA of two genes and correlating it with various sequence features of individual siRNAs, Reynolds et al at Dharmacon, Inc identified eight characteristics associated with siRNA functionality. These characteristics are used by rational siRNA design algorithm to evaluate potential targeted sequences and assign scores to them. Sequences with higher scores will have higher chance of success in RNAi. The table below lists the 8 criteria and the methods of score assignment. Criteria Description Score Yes No 1 Moderate to low (30%-52%) GC Content 1 point 2 At least 3 A/Us at positions 15-19 (sense) 1 point /per A or U 3 Lack of internal repeats (Tm*20C) 1 point 4 A at position 19 (sense) 1 point 5 A at position 3 (sense) 1 point 6 U at position 10 (sense) 1 point 7 No G/C at position 19 (sense) -1 point 8 No G at position 13 (sense) -1 point A sum score of 6 defines the cutoff for selecting siRNAs. All siRNAs scoring higher than 6 are acceptable candidates. *Tm = 79.8 + 18.5*logsub10( ) + (58.4 * GC%/100) + (11.8 * (GC%/100) 2 ) - (820/Length) For example, the Tm can be calculated as follows for the siRNA UUCUCCAGCUUCUAAAAUA Tm = 79.8 + 18.5*logsub10(0.05) + (58.4 * 31.6/100) + (11.8 * (31.6/100) 2 ) - (820/19) Tm = 32.19 There are two siRNA design tools which implement this siRNA design algorithm: one is offered by Dharmacon, Inc; the other is a downloadable Excel template, written by Maurice Ho at http://boz094.ust.hk/RNAi/siRNA. References Elbashir SM et al. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411:494-498. Elbahir SM et al. (2001). Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20:6877-6888. Elbashir SM et al. (2002). Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods. 26:199-213. Reynolds A, Leake D, Boese Q, Scaringe S, Marshall WS, Khvorova A. Rational siRNA design for RNA interference. Nat Biotechnol. 2004 Mar;22(3):326-30. http://www.basic.northwestern.edu/biotools/oligocalc.html Maurice Ho, Rational siRNA Design http://www.protocol-online.org/prot/Protocols/Rules-of-siRNA-design-for-RNA-interference--RNAi--3210.html
个人分类: ncRNA|2366 次阅读|0 个评论
[转载]siRNA Design
Huitian 2013-8-20 21:41
Rules for selecting siRNA targets on mRNA sequences : Targets should be located 50-100 nt downstream of the start codon (ATG). Search for sequence motif AA(N 19 )TT or NA(N 21 ), or NAR(N 17 )YNN, where N is any nucleotide, R is purine (A, G) and Y is pyrimidine (C, U). Target sequences should have a G+C content between 35-60%. Avoid stretches of 4 or more nucleotide repeats. Avoid 5'URT and 3'UTR, although siRNAs targeting UTRs have been shown to successfully induce gene silencing. Avoid sequences that share a certain degree of homology with other related or unrelated genes. How to obtain a mRNA or cDNA sequence for target selection: Before picking siRNA target on the gene of your interest, first you have to obtain its mRNA sequence from a nucleic acids database or sequence accession number as some siRNA design tools can take accession number as input. It is recommended to use the gene's RefSeq from NCBI , since the RefSeq represents non-redundant, curated and validated, thus most correct, sequences. RefSeq mRNA sequences have unique accession numbers which start with NM or XM, followed by 6 digits. For example, NM_123456 (curated mRNA sequence) or XM_0123456 (model mRNA sequence predicted by genome sequence analysis). There are several ways of searching and retrieving a RefSeq. Search the NCBI Gene database (Entrez Gene) by gene name or symbol at http://www.ncbi.nlm.nih.gov/gene/ and select the right gene of desired organism, go to the page of the gene, scroll down to the mRNA and Protein(s) section and look for mRNA sequences with a accession number started with NM or XM. Search Nucleotide database using Entrez query tool at http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Nucleotide and use Entrez Limits settings to restrict your query to the RefSeq database only select RefSeq from the Only from menu, this restricts the query to the RefSeq collection select mRNA from the Molecule menu, this restricts the query to mRNA RefSeq records Homology search The siRNA targets on the mRNA sequence of a gene should not share significant homology with other genes or sequences in the genome, therefore, homology search is essential for preventing off-target effects. Although most siRNA design tools provide BLAST search option, some simply use NCBI's BLAST tools which sometimes are quite slow. Here are some BLAST tools for homology search. NCBI Blast tool: Nucleotide-nucleotide BLAST (blastn) or Search for short, nearly exact matches Blat tool on UCSC Genome Website http://genome.ucsc.edu/cgi-bin/hgBlat Ensembl Blast http://www.ensembl.org/Multi/blastview Examples of RNAi target selection References Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001 May 24;411(6836):494-8. Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 2001 Jan 15;15(2):188-200. Reynolds A, Leake D, Boese Q, Scaringe S, Marshall WS, Khvorova A. Rational siRNA design for RNA interference. Nat Biotechnol. 2004 Mar;22(3):326-30. Tuschl Lab, The siRNA user guide . http://www.rnaiweb.com/RNAi/siRNA_Design/index.html
个人分类: ncRNA|2242 次阅读|0 个评论
[转载]实验室网络模拟实验室 Virtual Fab for Nano Device Design
chnfirst 2013-5-16 14:59
Virtual Fab for Nano Device Design http://amber.kist.re.kr/VirtualLab/ 注册页: http://amber.kist.re.kr/VirtualLab/signup.php
个人分类: 材料、专业|1 次阅读|0 个评论
[转载]【新书LAMMPS】Molecular Modeling for the Design of
chnfirst 2013-4-2 20:38
http://www.crcnetbase.com/doi/book/10.1201/b11590 本书的CRC出版信息 http://www.amazon.cn/Molecular-Modeling-for-the-Design-of-Novel-Performance-Chemicals-and-Materials/dp/1439840784 MolecularModelingfortheDesignofNovelPerformanceChemicalsandMaterials 出版日期: 2012年3月23日 Molecularmodeling(MM)toolsoffersignificantbenefitsinthedesignofindustrialchemicalplantsandmaterialprocessingoperations.WhiletheroleofMMinbiologicalfieldsiswellestablished,inmostcasesMMworksasanaccessoryinnovelproducts/materialsdevelopmentratherthanatoolfordirectinnovation.Asaresult,MMengineersandpractitionersareoftenseizedwiththequestion:HowdoIleveragethesetoolstodevelopnovelmaterialsorchemicalsinmyindustry?MolecularModelingfortheDesignofNovelPerformanceChemicalsandMaterialsanswersthisimportantquestionviaasimpleandpracticalapproachtotheMMparadigm.Usingcasestudies,ithighlightstheimportanceandusabilityofMMtoolsandtechniquesinvariousindustrialapplications.Thebookpresentsdetailedcasestudiesdemonstratingdiverseapplicationssuchasmineralprocessing,pharmaceuticals,ceramics,energystorage,electronicmaterials,paints,coatings,agrochemicals,andpersonalcare.Thebookisdividedintothemedchapterscoveringadiverserangeofindustrialcasestudies,frompharmaceuticalstocement.Whilenotgoingtooin-depthintofundamentalaspects,thebookcoversalmostallparadigmsofMM,andreferencesareprovidedforfurtherlearning.Thetextincludesmorethan100colorillustrationsofmolecularmodels. 显示更多 显示更少 ComputingTransportinMaterials ,M.Pinto,V.G.R.Palla,A.Nandgaonkar,chapter10 EditedbyBeenaRai,CRCPress2012,ISBN:978-1-4398-4078-8.
个人分类: LAMMPS|0 个评论
[转载]R and Analysis of Variance ( Mixed design)
ljxue 2013-3-22 21:40
http://personality-project.org/r/r.anova.html Mixed (between and Within) designs Now it's time to get serious. Appendix V contains the data of an experiment with 18 subjects, 9 males and 9 females. Each subject is given one of three possible dosages of a drug. All subjects are then tested on recall of three types of words (positive, negative and neutral) using two types of memory tasks (cued and free recall). There are thus 2 between-subjects variables: Gender (2 levels) and Dosage (3 levels); and 2 within-subjects variables: Task (2 levels) and Valence (3 levels). Get the data from the file and run the following analysis: aov.ex5 _ aov(Recall~(Task*Valence*Gender*Dosage)+Error(Subject/(Task*Valence))+(Gender*Dosage),ex5) Notice that you must segregate between- and within-subjects variables in your command. In the above example, I have put the within-subjects factors first with the within-subjects error term, followed by the between-subjects factors. datafilename=http://personality-project.org/r/datasets/R.appendix5.data data.ex5=read.table(datafilename,header=T) #read the data into a table data.ex5 #show the data aov.ex5 = aov(Recall~(Task*Valence*Gender*Dosage)+Error(Subject/(Task*Valence))+(Gender*Dosage),data.ex5 ) summary(aov.ex5) print(model.tables(aov.ex5,means),digits=3) #report the means and the number of subjects/cell boxplot(Recall~Task*Valence*Gender*Dosage,data=data.ex5) #graphical summary of means of the 36 cells boxplot(Recall~Task*Valence*Dosage,data=data.ex5) #graphical summary of means of 18 cells Should result in the following (extensive) output: datafilename=http://personality-project.org/r/datasets/R.appendix5.data data.example5=read.table(datafilename,header=T) #read the data into a table data.example5 #show the data Obs Subject Gender Dosage Task Valence Recall 1 1 A M A F Neg 8 2 2 A M A F Neu 9 3 3 A M A F Pos 5 4 4 A M A C Neg 7 5 5 A M A C Neu 9 6 6 A M A C Pos 10 7 7 B M A F Neg 12 8 8 B M A F Neu 13 9 9 B M A F Pos 14 10 10 B M A C Neg 16 ... SNIP .... 100 100 Q F C C Neg 17 101 101 Q F C C Neu 19 102 102 Q F C C Pos 19 103 103 R F C F Neg 19 104 104 R F C F Neu 17 105 105 R F C F Pos 19 106 106 R F C C Neg 22 107 107 R F C C Neu 21 108 108 R F C C Pos 20 aov.ex5=aov.ex5 = aov(Recall~(Task*Valence*Gender*Dosage)+Error(Subject/(Task*Valence))+(Gender*Dosage),data.example5 ) summary(aov.ex5) Error: Subject Df Sum Sq Mean Sq F value Pr(F) Gender 1 542.26 542.26 5.6853 0.03449 * Dosage 2 694.91 347.45 3.6429 0.05803 . Gender:Dosage 2 70.80 35.40 0.3711 0.69760 Residuals 12 1144.56 95.38 --- Signif. codes: 0 `***' 0.001 `**' 0.01 `*' 0.05 `.' 0.1 ` ' 1 Error: Subject:Task Df Sum Sq Mean Sq F value Pr(F) Task 1 96.333 96.333 39.8621 3.868e-05 *** Task:Gender 1 1.333 1.333 0.5517 0.4719 Task:Dosage 2 8.167 4.083 1.6897 0.2257 Task:Gender:Dosage 2 3.167 1.583 0.6552 0.5370 Residuals 12 29.000 2.417 --- Signif. codes: 0 `***' 0.001 `**' 0.01 `*' 0.05 `.' 0.1 ` ' 1 Error: Subject:Valence Df Sum Sq Mean Sq F value Pr(F) Valence 2 14.685 7.343 2.9981 0.06882 . Valence:Gender 2 3.907 1.954 0.7977 0.46193 Valence:Dosage 4 20.259 5.065 2.0681 0.11663 Valence:Gender:Dosage 4 1.037 0.259 0.1059 0.97935 Residuals 24 58.778 2.449 --- Signif. codes: 0 `***' 0.001 `**' 0.01 `*' 0.05 `.' 0.1 ` ' 1 Error: Subject:Task:Valence Df Sum Sq Mean Sq F value Pr(F) Task:Valence 2 5.389 2.694 1.3197 0.2859 Task:Valence:Gender 2 2.167 1.083 0.5306 0.5950 Task:Valence:Dosage 4 2.778 0.694 0.3401 0.8482 Task:Valence:Gender:Dosage 4 2.667 0.667 0.3265 0.8574 Residuals 24 49.000 2.042 print(model.tables(aov.ex5,means),digits=3) #report the means and the number of subjects/cell Tables of means Grand mean 15.62963 Task C F 16.6 14.7 rep 54.0 54.0 Valence Neg Neu Pos 15.3 15.5 16.1 rep 36.0 36.0 36.0 Gender F M 17.9 13.4 rep 54.0 54.0 Dosage A B C 14.2 13.5 19.2 rep 36.0 36.0 36.0 Task:Valence Valence Task Neg Neu Pos C 16.00 16.72 17.00 rep 18.00 18.00 18.00 F 14.56 14.22 15.28 rep 18.00 18.00 18.00 Task:Gender Gender Task F M C 18.93 14.22 rep 27.00 27.00 F 16.81 12.56 rep 27.00 27.00 Valence:Gender Gender Valence F M Neg 17.67 12.89 rep 18.00 18.00 Neu 17.44 13.50 rep 18.00 18.00 Pos 18.50 13.78 rep 18.00 18.00 ... snip .... , , Gender = M, Dosage = B Valence Task Neg Neu Pos C 10.00 11.67 12.33 rep 3.00 3.00 3.00 F 8.33 8.67 11.00 rep 3.00 3.00 3.00 , , Gender = F, Dosage = C Valence Task Neg Neu Pos C 20.67 21.67 21.33 rep 3.00 3.00 3.00 F 19.67 18.67 20.33 rep 3.00 3.00 3.00 , , Gender = M, Dosage = C Valence Task Neg Neu Pos C 18.00 19.00 19.00 rep 3.00 3.00 3.00 F 17.33 17.33 17.33 rep 3.00 3.00 3.00
2090 次阅读|0 个评论
[转载]IBM SOI technology: Cu-45HP
whyhoo 2013-1-30 22:55
A new breed of custom logic With Cu-45HP, you can leverage all the advantages of SOI technologyin a proven IBM custom logic offering. The design system capitalizeson IBM’s six generations of experience in SOI design and ongoingleadership in delivering high-performance custom silicon solutions fornetworking and storage applications. Cu-45HP is designed to provide apowerful platform for developing innovative semiconductor solutionsfor aerospace and defense, communications and performance-drivenapplications in other market segments. Performance, delivered The Cu-45HP design system is based on IBM’s sophisticated 45-nmSOI technology. This technology offers significant intrinsic perform-ance advantages over bulk CMOS-based semiconductors because of thedecreased junction capacitance provided by the oxide layer in SOI.Advanced strained silicon techniques, such as embedded silicon germa-nium and dual strain liners, enhance the inherent SOI performancebenefits.Cu-45HP leverages dual logic oxide technology. The design system’s12-angstrom logic devices enable you to trade off performance andpower; its 25-angstrom logic devices can help you effectively managehigher I/O voltage while still providing performance advantages overcorresponding 65-nm devices.Because SOI leverages buried oxide isolation and floating bodies in lieuof well contacts, extremely high levels of integration are possible inCu-45HP. Backed by IBM’s record of success in implementing large,complex semiconductors, you can confidently exploit this densityadvantage in developing high-performance, sophisticated system-on-a-chip (SoC) solutions. Building blocks for differentiation Cu-45HP offers an array of compilable eDRAM options thatfeature deep trench capacitors for superior soft error ratecharacteristics. Density-optimized options are designed toprovide high bandwidth; performance-optimized options aredesigned to provide fast random cycle times. The introduc-tion of the fast random-cycle time eDRAMs gives you theflexibility of replacing small blocks of embedded SRAM orlow bit-count embedded SRAMs with eDRAM for leakageand area benefits, while still maintaining high performance.Other memory options, including a broad spectrum of com-pilable SRAMs, provide you with the ability to make trade-offs for active and standby current, area, bandwidth, latencyand performance. The variety of possible memory configura-tions enables extensive customization for optimized memorysolutions across a wide range of applications.Additional design flexibility is available through a broad port-folio of intellectual property (IP) that includes: ●IBMHSS cores that support a broad range of industrystandards and offer superior jitter and equalization characteristics ●IBMPowerPCembedded processors for performance andscalability advantages in SoC designs ●The Ready for SOI Technology portal (offered by the SOIIndustry Consortium) for design building blocks that youcan use to harness the benefits of SOI technology ●Other industry-leading design building blocks availablethrough an extended ecosystem of IBMBusiness PartnersBy leveraging proven IP, you can reduce design time and risk while differentiating your design—differentiation thatcan help you remain competitive in a dynamic business environment. A shared goal—first-pass design success Cu-45HP is designed to help you achieve first pass designsuccess. Statistical timing techniques, holistic designapproaches and the ability to leverage both industry-standard and innovative IBMtools and models provide you with amyriad of options to overcome the challenges of designingwith advanced technologies. The IBMend-to-end designphilosophy, with advances such as concurrent chip and pack-age design, an integrated noise- and power-analysis environ-ment and at-speed structural test, can enable you to verifydesign performance and design around potential pitfallsbefore they become issues in system-level hardware. Cu-45HP is here, and it’s SOI SOI technology opens up new avenues for innovation, deliv-ering performance and power advantages that bulk CMOStechnologies cannot easily match. Yet the SOI manufacturingprocess is competitive with bulk-based CMOS manufacturingprocesses, where bulk isolation and other processes continueto grow in complexity—and costs—with scaling. Take advantage of IBM’s technology leadership and engineer-ing expertise with IBM Cu-45HP, an innovative custom logicsolution built on a proven technology base—the kind of pio-neering technology that offers you the potential to take yoursemiconductor design performance to new heights. Features and specifications Cu-45HP features: ●Dual logic oxide technology, with 12-angstrom logicdevices for significant performance advantages and 25-angstrom logic devices for I/O features ●Multiple Vtdesign libraries (ultra high, super high, highand regular, with the ultra high Vtlibrary offering the low-est leakage and the regular Vtlibrary offering the highestperformance) ●Support for both 9-track and 12-track design libraries fordensity or performance advantages, respectively ●Up to a seven times reduction in the soft error rate (due tothe smaller size of the well area between the drain andsource of SOI-based transistors compared with bulk CMOSdevices) ●A broad range of packaging options 原文见 http://public.dhe.ibm.com/common/ssi/ecm/en/tgd03009usen/TGD03009USEN.PDF
个人分类: 科学|1698 次阅读|0 个评论
[转载]IBM HKMG SOI technology: Cu-32
whyhoo 2013-1-30 22:47
Accelerate network performance with an application- tuned 32 nm, HKMG custom logic design system It’s never ending. The communications infrastructure must evolve and adapt to stay ahead of exponentially growing numbers of internet-connected devices and skyrocketing volumes of data traffic. Semiconductor solutions targeted for this space must deliver more performance, better power efficiency and added function in less circuit area. Gaining and sustaining a competitive advantage in this environment means implementing advanced semiconductor technology that offers tan-gible differentiation and delivers predictable results. IBM’s 32 nm custom logic offering, Cu-32, is designed to help you meet all these challenges. Achieve higher throughput at system level The IBM Cu-32 design system takes advantage of a breakthrough in the way semiconductor chips are manufactured: silicon-on-insulator (SOI), high-k metal gate (HKMG) technology. The technology is optimized to help you achieve new levels of performance, power efficiency and integration in your designs for higher throughput at the system level. For example, compared with 45 nm SOI technology, IBM HKMG SOI technology offers: ●Up to 25 percent improvement in chip performance ●Up to 30 percent lower power ●Up to 50 percent area savings for logic and memory Built on the seventh generation of IBM SOI technology, Cu-32 enables you to draw on IBM leadership in developing and manufacturing advanced semiconductor technology. You can leverage a proven technology platform designed to meet the demands of solutions for smarter communications. And you can do it today. Differentiate your silicon IBM Cu-32 features application-optimized embedded memories and high-speed SERDES (HSS) cores designed to deliver tangible differentiation. The Cu-32 intellectual property (IP) portfolio includes: ●Algorithmic multiport (AMP) memories. The Cu-32 AMP memory compiler enables you to create a broad range of memory subsystems that improve on the memory-operations-per-second of the underlying single- and multi-ported embedded SRAMs (eSRAMs) or embedded DRAMs (eDRAMs) that are used to build them. The AMP memory structures are multi-ported memories that are lower power and higher density compared to conventional physical multi-ported memories, which carry the power and area overhead of additional circuits. ●Trench-capacitor-based eDRAMs. IBM’s innovative eDRAM technology is optimized to deliver high performance and low power, and enables you to incorporate over one gigabit of memory in SoC designs. IBM eDRAMs feature significantly lower soft error rates than eSRAM alternatives, and can provide up to a 3-fold density improvement and up to a 20-fold reduction in leakage power compared with eSRAMs. More than 3,000 configurations are possible with the Cu-32 eDRAM compiler. ●High performance, low power ternary CAMs (TCAMs). Cu-32 features one of the industry’s fastest, lowest-power ternary TCAMs to accelerate lookups for high speed routers, switches and networking hardware used in cloud computing. ●A broad portfolio of HSS cores. IBM’s HSS cores deliver superior jitter performance and equalization properties across a wide range of interface standards. The Cu-32 HSS offerings include an advanced 28G backplane core supporting the 32G Fibre Channel standard. Additional IP building blocks and design enablement resources are available through IBM and third party suppliers. Boost performance with unique packaging architectures Packaging solutions for IBM Cu-32 are designed to boost performance beyond silicon scaling alone and benefit from pioneering research, close collaboration with industry leaders and integration of advanced materials. The Cu-32 packaging portfolio comprises a wide range of options that take advantage of chip/package co-design, which enables package optimization to support high link rates and density.IBM Cu-32 packaging options include a low-loss carrier and die stacking. The low loss carrier provides improved signal integrity. The unique die stacking architecture, using 3D through silicon vias (TSV), provides the ability to mix and match logic, memory and technology nodes and delivers significantly increased functional density, lower power and higher performance. Die stacking is a semi-custom offering, available now on a limited basis and planned for general availability in 2013. 原文见 http://public.dhe.ibm.com/common/ssi/ecm/en/tgd03018usen/TGD03018USEN.PDF
个人分类: 科学|1949 次阅读|0 个评论
[惊悚][杀生][高清1280版BD-RMVB.国语中字][2012最新黄渤、任达
lcj2212916 2012-12-25 18:22
◎译  名 杀生 ◎片  名 Design Of Death ◎年  代  2012 ◎国  家 中国 ◎类  别 剧情/ 喜剧 /悬疑/惊悚 ◎语  言 普通话 ◎字  幕  中文 ◎IMDB评分 N/A ◎IMDB链接 www.imdb.com/title/tt2290645 ◎文件格式  高清 1280版BD-RMVB ◎视频尺寸 1280 x 564 ◎文件大小 1CD 1.14GB ◎片  长 1h 48mn ◎导  演 管虎 Hu Guan ◎主  演 黄渤 Bo Huang ....牛结实   任达华 Simon Yam ....医生“我”   余男 Nan Yu ....马寡妇   苏有朋 Alec Su ....长寿镇牛医生   马精武 Jingwu Ma ....长寿镇镇长   梁静 Jing Liang ....长寿镇接生婆   王迅 Xun Wang ....长寿镇油漆匠   胡继光 Ji-guang Hu ◎简  介    中国西南、与世隔绝、群山环抱中有个寨子,是个人皆长寿、规矩自成之地,清时皇帝赐名“长寿镇”。某日突爆传染病,地方官派医生(任达华 饰)前往诊治,他在镇子外发现奄奄一息的牛结实(黄渤 饰)。进寨后,往日温厚的村民一反常态,不仅对牛结实拒施援手、避若瘟疫,更迁怒于医生多管闲事,老镇长(马精武 饰)亲自带着长寿镇医生(苏有朋 饰)和接生婆(梁静 饰)、油漆匠,老族长等人千万百计的阻挠医生对牛结实的救援,牛结实最终没能被救活,医生也找不到此人暴毙的原因。镇民们对医生的不欢迎不合作态度,令医生很沮丧,正当他准备离开的时候,无意中发现了一个被全镇民众一起隐藏在山崖上的一个秘密,带着重重疑惑医生决定暗中走访长寿镇,直到他偶遇一个男孩,长寿镇迷案的真相才一步步揭开……   该片改编自陈铁军的中篇小说《设计死亡》。 下载地址 : http://www.ctdisk.com/file/14234993 http://radarew.5d6d.net/thread-1077-1-1.html
3821 次阅读|0 个评论
Some Basic Optical System Design specifications
robinmartin 2012-12-5 19:00
Optical Designers may be ed by various parameters in the system, even forget the basic request. When U counter these situations, the list below may awake u from the miscellaneous data. The Optical system purpose: Resolve a specified minimum-sized object over a desired field of view.(1.5 line pairs may acquire , 4 line pairs to recognize and 7 line pairs to identify an object.) The system may consist two parts: the optical element and the detector. The smallest desired resolution element should match the detector's Nyquist Frequency, and the field and the resolution should be the optical problem. There exist other parameters: Basic system parameters: Object distance Image distance Object to Image total track focal length F-number(infinity project) and numerical aperture( finite project) Entrance pupil diameter Wavelength band(for monochromatic system the pressure and nature broaden should also be considered) Wavelength and weights for 3 or 5 lamdas Full field view of view(ambiguous when refer to diagonal or horizontal) Magnification(finite conjugate but entanglement with the infinite project by beam compress factor) Zoom ratio Image surface size and shape Detector type Optical Performance: Transmission Relative illumination(vignetting) Encircled energy MTF as a function of line pairs/mm) Distortion Field curvature Lens System Number of elements Glass versus plastic Aspheric surfaces Diffractive surfaces Coatings Sensor Sensor type Full diagonal Number of pixels(horizontal and vertical) pixel pitch(horizontal and vertical) Nyquist frequency at sensor line pairs/mm Packaging Object to image total track Entrance and exit pupil location and size Back focal distance Maximum diameter Maximum length Weight Environment Thermal soak range to perform over Thermal soak range to survive over vibration shock other(condensation, humidity, sealing,etc) Illumination source type Power Radiometry issues source relative illumination illumination method veiling glare and ghost image Radiometry issues, image Transmission(L-H invariant n*h*Sin == n'*h'* Sin ) relative illumination stray light attenuation Schedule and cost Number of systems required initial delivery date target cost goal
个人分类: 设计参考|24 次阅读|0 个评论
[转载]PFRED: Open Source siRNA and ASO Design Tool
genesquared 2012-11-12 09:59
PFRED http://pfred.org/ Launch PFRED Source Code (coming soon...) Key FeaturesOligo enumeration Property calculations Cross-species homology GC content SNPs Intron-exon boundary Duplex thermodynamics Efficacy prediction Off-target matches Oligo visualization An Open Source siRNA and ASO Design Tool Introduction PFRED stands for Pf izer R NAi E numeration and D esign. PFRED is a client-server software system designed for selecting potent and specific siRNAs or RNase H-dependent antisense (ASO) agents. Highly effective sequences for post transcriptional gene regulation are chosen in PFRED using bioinformatics algorithms built upon careful mining of the sequence-activity relationships found in public datasets as well as internal collections. The tool provides researchers with a user friendly interface where the only required input is the gene ID information for the target being studied. It returns a list of properties that might contribute to the effectiveness of an siRNA or ASO; these properties include human transcripts and cross-species homology, GC content, SNPs, intron-exon boundary, duplex thermodynamics, efficacy prediction score and off-target matches. An automated oligonucleotide selection procedure is available in PFRED to quickly select one potential set of sequences with an appropriate property profile. The selection protocol can be customized by the user through changes of the selection cutoffs or the addition of alternate design parameters and algorithms References HELM: A Hierarchical Notation Language for Complex Biomolecule Structure Representation. Tianhong Zhang*, Hongli Li, Simon Xi, Robert V. Stanton and Sergio H. Rotstein, JCIM, In Press PFRED: A Computational Tool for siRNA and Antisense Design. Simon Xi, Qing Cao, Christine Lawrence, Tianhong Zhang, Simone Sciabola, Sergio Rotstein, Jason Hughes, Daniel Caffrey and Robert Stanton, Submitted For further information, please e-mail "biomolecule.toolkit at gmail.com" A Biomolecule Toolkit Application
个人分类: siRNA|1931 次阅读|0 个评论
美国的垃圾期刊
xupeiyang 2012-11-7 12:23
近三年从来未被引用或被引用才几次,或H指数为零和极低的期刊。 每种期刊的详细数据,请你在底下的“数据来源”分析平台查看。 Title SJR H index Total Docs. (2011) Total Docs. (3years) Total Refs. Total Cites (3years) Citable Docs. (3years) Cites / Doc. (2years) Ref. / Doc. Country 5401 Surface Design Journal 0,100 1 76 124 0 0 117 0,00 0,00 5402 Synthesis Lectures on Antennas 0,106 2 0 5 0 0 4 0,00 0,00 5403 Synthesis Lectures on Computer Science 0,126 1 2 1 80 0 1 0,00 40,00 5404 Synthesis Lectures on Electrical Engineering 0,104 0 4 7 270 0 7 0,00 67,50 5405 Synthesis Lectures on Technology, Management and Entrepreneurship 0,126 0 1 1 17 0 1 0,00 17,00 5406 Synthesis project. Research synthesis report, The 0,000 0 1 0 0 0 0 0,00 0,00 5407 TAPPI European PLACE Conference 0,100 2 76 59 10 0 57 0,00 0,13 5408 Technical Report - University of Texas at Austin, Center for Research in Water Resources 0,101 0 8 25 590 0 25 0,00 73,75 5409 Television Quarterly 0,101 1 0 26 0 0 15 0,00 0,00 5410 Texas nursing 0,102 2 3 13 0 0 13 0,00 0,00 5411 Theater 0,100 2 16 57 56 0 48 0,00 3,50 5412 Theoria: A Journal of Social and Political Theory 0,000 0 9 0 0 0 0 0,00 0,00 5413 Theory in Action 0,000 0 1 0 0 0 0 0,00 0,00 5414 Thomas Wolfe Review 0,101 1 0 43 0 0 34 0,00 0,00 5415 Toxicity report series 0,000 1 2 0 0 0 0 0,00 0,00 5416 Translation Review 0,101 1 0 39 0 0 36 0,00 0,00 5417 Uncoverings 0,126 0 7 1 0 0 1 0,00 0,00 5418 University of Pennyslvania Working Papers in Linguistics 0,000 1 23 0 0 0 0 0,00 0,00 5419 Urban Habitats 0,000 0 9 0 300 0 0 0,00 33,33 5420 USDA Forest Service - General Technical Report RMRS-GTR 0,100 5 13 48 1.532 0 48 0,00 117,85 5421 USDA Forest Service - Research Note PNW-RN 0,104 1 0 7 0 0 7 0,00 0,00 5422 USDA Forest Service - Research Note RMRS-RN 0,103 1 6 9 203 0 9 0,00 33,83 5423 USDA Forest Service - Research Papers PNW-RP 0,101 1 2 17 69 0 17 0,00 34,50 5424 USDA Forest Service - Research Papers RMRS 0,102 3 6 15 325 0 15 0,00 54,17 5425 USDA Forest Service - Resource Bulletin PNW-RB 0,105 1 3 5 47 0 5 0,00 15,67 5426 US Department of Agriculture, Forest Service - Resource Bulletin 0,106 2 0 4 0 0 4 0,00 0,00 5427 Veterinary Economics 0,100 2 131 409 0 0 143 0,00 0,00 5428 Veterinary heritage : bulletin of the American Veterinary History Society 0,101 1 2 21 0 0 21 0,00 0,00 5429 Victorian Newsletter 0,101 2 18 26 352 0 23 0,00 19,56 5430 VII: An Anglo-American Literary Review 0,000 0 5 0 0 0 0 0,00 0,00 5431 Virginia Quarterly Review 0,100 2 42 130 0 0 114 0,00 0,00 5432 Visible Language 0,000 0 13 0 0 0 0 0,00 0,00 5433 VM+SD Visual Merchandising and Store Design 0,000 0 28 0 0 0 0 0,00 0,00 5434 Voices - Journal of New York Folklore 0,101 0 16 45 25 0 8 0,00 1,56 5435 Wallace Stevens Journal 0,100 3 0 50 0 0 43 0,00 0,00 5436 Watermark (Archivists and Librarians in the History of the Health Sciences) 0,102 1 0 12 0 0 12 0,00 0,00 5437 Water Resources Research Institute News of the University of North Carolina 0,101 0 15 32 34 0 25 0,00 2,27 5438 Western American Literature 0,101 2 15 38 377 0 35 0,00 25,13 5439 Western Journal of Emergency Medicine 0,000 2 134 0 2.422 0 0 0,00 18,07 5440 Wildlife Society Bulletin 0,000 49 75 0 2.746 0 0 0,00 36,61 5441 Windows in time 0,106 1 2 4 0 0 4 0,00 0,00 5442 Word of Mouth 0,101 1 23 40 125 0 40 0,00 5,43 5443 Working Paper of the Helen Kellogg Institute for International Studies 0,101 1 6 27 305 0 27 0,00 50,83 5444 Working Papers in Educational Linguistics 0,000 0 6 0 0 0 0 0,00 0,00 5445 World Medical and Health Policy 0,000 3 34 0 903 0 0 0,00 26,56 数据来源: http://www.scimagojr.com/journalrank.php?category=0area=0year=2011country=USorder=tcmin=0min_type=cdpage=108
个人分类: 引证分析|2623 次阅读|0 个评论
Springer新书-基于网络药理学的个体化治疗与药物组合理性设计
热度 1 phenome 2012-10-15 14:18
在Springer出版的新书《Systems Biology in Cancer Research and Drug Discovery》中贡献了一个章节: The Principle of Rational Design of Drug Combination and Personalized Therapy Based on Network Pharmacology (基于网络药理学的个体化治疗与药物组合理性设计原理) The Principle of Rational Design of Drug Combination and Personalized Therapy Ba.pdf
个人分类: 网络药理学|3023 次阅读|1 个评论
2nd ICMTRFDM - CALL FOR PAPERS
majian 2012-9-13 12:46
原定10月初召开的第二届轨道交通设计及管理国际会议现推迟至12月3日举行。 会议已经邀请包括UIUC, UCL, STANFORD等国际名校相关专家参会做特邀报告,诚邀国内外同行与会,会议在香港召开,仅收取800港币注册费。 The 2nd International Conference on Mass Transit Rail Facilities Design and Management City University of Hong Kong, Hong Kong, on December 3 rd , 2012 The topics include but are not limited to: • Pedestrian and passenger flow studies for rail and mass transit facilities; • Performance-based fire safety engineering, conditional health monitoring mass transit rail system; • Planning, development and facilities management in subway/ mass transit rail services; • Signal, train control, equipment, video surveillance and infrastructure for subway/ mass transit rail system; • Security, safety, evacuation and emergency response study for subway/ mass transit rail system; • Quality, Reliability, Risk Analysis and Maintainability Engineering and Management for mass transit rail services. • Energy saving, renewable energy consumption for subway/ mass transit rail services Other topics relating to mass transit facilities and etc. Abstract Submission Due Date: October 15 th , 2012 Notification of Acceptance: October 20 th , 2012 Full Paper received: November 10 th , 2012 Conference Date: December 3 rd , 2012 • attend the conference only • attend the conference present a paper For those who intend to present his or her works in the conference, please submit a short abstract (approximate 250 words) and biographical information to the organizing committee by email to ICMTRFDM@gmail.com A Registration Fee of HK$800 is required for attending the workshop/ conference and presenters and participants are responsible for all of their own traveling, meals and other expenses . If you have any questions, please feel free to contact us at ICMTRFDM@gmail.com .
个人分类: 百家|3091 次阅读|0 个评论
Two-year resolution
EUVplasma 2012-8-7 02:47
1. X-ray application (absorption, diffraction...) 2. Molecular spectroscopy 3. Chamber design 4. LabView 5. Matlab
2789 次阅读|0 个评论
如何解决男性小便池的问题?
热度 2 liwei999 2012-7-21 01:07
如何解决男性小便池的问题? 作者: mirror (*) 日期: 07/20/2012 06:53:32 对镜某“家里有个男孩,厕所就要遭殃了”的说法,有些知音有共鸣了。尿到外边的大问题是气味不好。 如何能解决这个难题? Quote 有朋友跟帖说: 男厕小便池的问题,我想过,也观察过很多。发现有办法解决的: 在有的男厕里,小便池前是个台阶。有了这个台阶,大家就潜意识地觉得站在上面才算到位。不站上面,离着小便池太远,别扭。这个台阶,就起到了很好的定位作用。 改进的办法:台阶做成网状、格状(比如浴室、泳池边上那种)可漏液体的各种材质。这样,“收尾”时就算有漏到外面的,也不明显,不会影响到之后的人的心理。台阶的强迫性还是很大地。 这样的解决方案有个很大的问题。也是设计人员常犯的错误:把解决问题当成了目的,破坏了整个厕所的卫生、美观的初始目的。目前的设计,容易清扫。只要清扫勤一些就可以解决问题。只是成本高些。 做台阶是为了让人们前进一步。这个思考比贴“请进一步”的标语要好。但是进一步的“发挥”,是原来还不错的方案走入了绝境。有台阶的设计原本是为了不漏、少漏。如果这个方案奏效的话,把“台阶做成网状、格状(比如浴室、泳池边上那种)可漏液体的各种材质”的思考就会失效。因为没有那么多漏可接了。这个设计好像是“进一步”的措施,可惜与原来的设计不匹配。网状、格状的设计增加的表面积,增大了清扫的难度。 怎么办?思路有几类。1)不(让)漏,2)虽有漏,但不味儿,3)虽有漏,勤打扫。 大尿池的设计,看上去是简单了。但是由于放尿区域的面积增大,反而不好清扫,维持清洁。也是一类失败的设计。 ---------- 就“是”论事儿,就“事儿”论是,就“事儿”论“事儿”。 其实废弃的暖瓶(竹子的那种最好)就是非常好的夜壶, 作者: 立委 日期: 07/20/2012 12:11:26 大小合适,不漏,有盖,没味,隐秘。 当年十冬腊月的夜晚复习备考,这种夜壶不知 道解了多少急。 唯一的缺点是平日朋友进来口渴了,或者自己备考糊涂了,一不小心用它冲茶就尴尬万分了。
个人分类: 镜子大全|4804 次阅读|3 个评论
Fly-Buck Design
tinghai89922 2012-7-2 17:01
Fly-Buck Design
!!! Excerpted from TI The Fly-Buck Design Calculator Tool assists designers with routine calculations for the 2W TPS55010 isolated DC/DC Converter. Two versions are available to support a single or a dual output configuration. The tool helps the user select a transformer, the sense resistors, and the power diode as well as the input, output, compensation, and primary capacitors. All equations used in the tool are shown with the corresponding datasheet equation. Primary and secondary waveforms of the voltage and current are also displayed. Fly-Buck Design Calculator Tool : TPS55010Tool_DualOutput.xls and TPS55010Tool_SingleOutput.xls TPS55010: DC/DC Converter (Integrated Switch), 2.95V To 6V Input, 2W, Isolated DC/DC Converter with Integrated FETS tps55010.pdf Other useful documents: slvu494.pdf and slvu459.pdf topology
5554 次阅读|0 个评论
[转载]控制推荐经典资料
热度 2 onewaystreet 2012-5-19 18:32
线性系统: 属陈启宗的《Linear sysytem thoery and design》和凯拉斯的《Linear systems》。 最优控制理论从运筹学等数学理论发展过来,推荐一本《The robust maximum principle》,这本书理论起点较高,几乎囊括了最优控制的所有精华。 系统辨识的经典是瑞典的L.荣,在此基础上的自适应控制的经典是Goodwin的《自适应预测,滤波和控制》。 关于鲁棒控制的经典力作,无可厚非当属周克敏教授的《鲁棒与最优控制》,是美国各大研究生院的指定教材,据不完全统计周教授的SCI论文和这本书已被引用六千余次,这是我们搞鲁棒控制的偶像! 关于非线性控制著作:Hassan K. Khalil 写的曾获IFAC控制工程教材奖的《非线性系统》有中译版的。
个人分类: 控制|4645 次阅读|3 个评论
Research on the Conversion from Design Features to Machining
bshen 2012-3-30 10:10
Huabing Ouyang ,B.Shen. Research on the Conversion from Design Features to Machining Features Faced on STEP-NC. IEEE Conference of 2011 3rd International Conference on Measuring Technology and Mechatronics Automation(ICMTMA),2011,3:103-106 .(EI: 20111313853572), EI : 20111313853572
个人分类: 学术论文|2730 次阅读|0 个评论
基于EZ-USB芯片的通用USB控制器硬件设计方法
bshen 2012-3-30 09:25
沈斌、邵四维.基于 EZ-USB 芯片的通用 USB 控制器硬件设计方法.制造技术与机床, No.6,2009:28~30 Universal USB Controller Hardware Design Method Based on EZ-USB Chip.MANUFACTURING TECHNOLGY MACHINE TOOL,No.6, 2009:28~30 CSCD
个人分类: 学术论文|2153 次阅读|0 个评论
* Nanoscale Res. Lett. 6 (2011)0422
jlkou 2012-3-28 21:30
* Nanoscale Res. Lett. 6 (2011)0422
Title: Optimizing the design of nanostructures for improved thermal conduction within confined spaces, Nanoscale Res. Lett. 6 (2011)0422 Authors: Jianlong Kou, Huiguo Qian, Hangjun Lu, Yang Liu, Yousheng Xu, Fengmin Wu, Jintu Fan 2011-6-422(Nanoscale Res.Lett.).pdf Figure 1 The design sketch of the total heat conduction structure. This desgin is from the interior of an electronic device to micro space, which includes two sections: I represents the composite stru ...
5048 次阅读|0 个评论
Design of high strength Fe-(P, C)-based bulk metallic glass
sfguo 2012-2-13 21:27
Design of high strength Fe-(P, C)-based bulk metallic glasses with Nb addition Sheng-feng GUO a , , , Ye SHEN b Abstract Bulk metallic glass (BMG) rods Fe 71 Mo 5- x Nb x P 12 C 10 B 2 ( x =1, 2, 3, 4 and 5) with diameter of 1 or 2 mm were synthesized by copper mold casting. The effects of Nb substitution for Mo on the structure, thermal and mechanical properties of Fe 71 Mo 5- x Nb x P 12 C 10 B 2 alloys were studied by X-ray diffraction, differential scanning calorimetry and compressive testing. The results show that the substitution of Nb for Mo leads to a decreased glass forming ability, but with plasticity of 1.0%, the fracture strength of Fe 71 Mo 2 Nb 3 P 12 C 10 B 2 alloy increases up to 4.0 GPa. The improvement of the fracture strength is discussed in terms of the enhancement of atomic bonding nature and the favorite formation of a network-like structure due to the substitution of Nb for Mo. http://www.sciencedirect.com/science/article/pii/S1003632611610327
个人分类: 非晶前沿|3468 次阅读|0 个评论
2004MATLAB simulations for radar systems design
lcj2212916 2012-2-3 17:09
共686页。 网盘直接下载地址: http://www.ctdisk.com/file/4465777
2120 次阅读|0 个评论
[转载]REGRESS Multiple linear regression using least squares
ppthelion 2011-11-8 20:55
. B = REGRESS(Y,X) returns the vector B of regression coefficients in the linear model Y = X*B. X is an n-by-p design matrix, with rows corresponding to observations and columns to predictor variables. Y is an n-by-1 vector of response observations. REGRESS 多元线性回归——用最小二乘估计法 B = REGRESS(Y,X) , 返回值为线性模型Y = X*B的回归系数向量 X ,n-by-p 矩阵,行对应于观测值,列对应于预测变量 Y ,n-by-1 向量,观测值的响应(即因变量,译者注) = REGRESS(Y,X) returns a matrix BINT of 95% confidence intervals for B. BINT,B的95%的置信区间矩阵 = REGRESS(Y,X) returns a vector R of residuals. R,残差向量 = REGRESS(Y,X) returns a matrix RINT of intervals that can be used to diagnose outliers. If RINT(i,:) does not contain zero, then the i-th residual is larger than would be expected, at the 5% significance level. This is evidence that the I-th observation is an outlier. RINT,区间矩阵,该矩阵可以用来诊断异常(即发现奇异观测值,译者注)。 如果RINT(i,:)所定区间没有包含0, 则第i个残差在默认的5%的显著性水平比我们所预期的要大, 这可说明第i个观测值是个奇异点 (即说明该点可能是错误而无意义的,如记录错误等,译者注) = REGRESS(Y,X) returns a vector STATS containing the R-square statistic, the F statistic and p value for the full model, and an estimate of the error variance. STATS,向量,包括R方统计量,F统计量,总模型的p值(还不清楚) 和方差的一个估计(还不清楚) = REGRESS(Y,X,ALPHA) uses a 100*(1-ALPHA)% confidence level to compute BINT, and a (100*ALPHA)% significance level to compute RINT. 用100*(1-ALPHA)%的置信水平来计算BINT, 用(100*ALPHA)%的显著性水平来计算RINT X should include a column of ones so that the model contains a constant term. The F statistic and p value are computed under the assumption that the model contains a constant term, and they are not correct for models without a constant. The R-square value is one minus the ratio of the error sum of squares to the total sum of squares. This value can be negative for models without a constant, which indicates that the model is not appropriate for the data. X应该包含一个全“1”的列,这样则该模型包含常数项。 F统计量和p值是在模型有常数项的假设下计算的, 如果模型没有常数项,则计算得的F统计量和p值是不正确的。 the R-square value is one minus the ratio of the error sum of squares to the total sum of squares.(此句无法把握,请高手帮忙~~!) 若模型没有常数项,则这个值可以为负值,这也表明这个模型对数据是不合适的。 (即数据不适合用多元线性模型,译者注)If columns of X are linearly dependent, REGRESS sets the maximum possible number of elements of B to zero to obtain a "basic solution",and returns zeros in elements of BINT corresponding to the zero elements of B.如果X的列是线性相关的,则REGRESS将使B的元素中“0”的数量尽量多,以此获得一个“基本解”并且使B中元素“0”所对应的BINT元素为“0”。REGRESS treats NaNs in X or Y as missing values, and removes them.REGRESS 将X或者Y中的NaNs当作缺失值处理,并且移除它 rcoplot(r,rint) displays an errorbar plot of the confidence intervals on the residuals from a regression. The residuals appear in the plot in case order. Inputs r and rint are outputs from the regress function. he interval around the first residual, shown in red, does not contain zero. This indicates that the residual is larger than expected in 95% of new observations, and suggests the data point is an outlier. 这是个画残差的函数,红色的表示超出期望值的数据 圆圈代表残差的值,竖线代表置信区间的范围
个人分类: Study_little_thing|1772 次阅读|0 个评论
Introduction to Molecular Epidemiology and Study Design (Ι)
molecularepi 2010-9-20 13:11
个人分类: 分子流行病学介绍(Introduction to Molecular Epide|8 次阅读|0 个评论
[转载]找书备忘:Experimental Design for the Life Sciences
cranelover 2010-3-31 13:12
转一下一个读者的读书笔记 http://book.douban.com/review/1450874/ 原文在:   http://lijuan.yo2.cn /2008/07/22/reading- experimental-design- for-the-life-science s-chapter1-why-you-n eed-to-care-about-de sign/   http://lijuan.yo2.cn /2008/07/23/reading- experimental-design- for-the-life-science s-chapter2-starting- with-a-well-defined- hypothesis/   http://lijuan.yo2.cn /2008/07/23/reading- experimental-design- for-the-life-science s-chapter3-between-i ndividual-variation- replication-and-samp ling/   http://lijuan.yo2.cn /2008/07/25/reading- experimental-design- for-the-life-science s-chapter4-different -experimental-design s/   还有一个flowchart在:   http://lijuan.yo2.cn /2008/07/25/reading- experimental-design- for-the-life-science s-flowchart/      Chapter 1 Why you need to care about design       * Experimental design is more about common sense, biological insight and careful planning.    * Poor experimental designs waste time and money, also have ethical issues.    * Every statistical test have slightly different assumptions, so it is essential to decide in advance how you will analyse your data when you have collected them.    * The two major goals of designing experiments are to minimise random variation and account for confounding factors.         下面是新手们经常有的两个认识误区:   Myth1 It does not matter how you collect your data, there will always be a statistical 'fix' that will allow you to analyse them.   Myth2 If you collect lots of data something interesting will come out, and you'll be able to detect even very subtle effects.      Chapter 2 Starting with a well-defined hypothesis      A hypothesis is a clear statement articulating a plausible candidate explanation for observations.It should be constructed is such a way as to allow gathering of data that can be used to either refute or support this candidate explanation.      For example:       1. Questions: why does chimp activity vary during the day?    2. Hypotheses: Chimp activity pattern is affected by feeding regime.    3. Predictions: The fraction of time that a chimp spends moving around will be higher in the hour aroung feeding time than at other times of day.      Make sure that your experiment allows you to give the clearest and strongest evidence for or against the hypothesis.   Make sure that you can interpret all possible outcomes of your experiment.      Pilot study: Exploration of the study system conducted before the main body of data collection in order to refine research aims , data collection and analysis techniques.      Correlational study's advantages:       * we handle them with much less time;    * We do not affect other functions;    * We are dealing with biologically relevant variation      Manipulative experiment's advantages:       * without third variables;    * without reverse causation;      A more efficient approach might be to begin with a large correlational study to see which factors seem to be important. Once potentially influential factors had been found, manipulative studies could be used to confirm and refine these findings.      There is no perfect study, but a little care can produce a good one instead of a bad one.      Chapter 3 Between-individual variation,replication and sampling      Whenever we carry out an experiment, we are trying to find ways to remove or reduce the effects of random variation, so that the effects that we care about can be seen more clearly.      Replication involves making the same manipulations and taking the same measurements on a number of different experimental subjects. Replication is a way of dealing with the between-individual variation due to the random variation that will be present in any life science experiment.      Replicate measures must be independent of each other: Techinicallly, statisticians talk about there being no correlation between the deviations of individuals within a group.If this is the case, this will have the important effect of meaning that if we examine a group of independent individuals their deviations will tend to cancel out, and the mean of the sample will close to the mean of the population.      Pseudoreplication is a problem that has to be addressed by biologists and not by statisticians.   Accept that sometimes pseudoreplication is unavoidable, so the key if you can't replicate fully is to be aware of the limitations of what you can conclude from your data.      Number of replicates: It should be big enough to give you confidence that you will be able to detect any biologically meaningful effects that exist, but not so big that some sampling was unnecessary.       * Educated guesswork: reference on previous similar studies.    * Formal power analysis: statistical power is the probability that a particular experiment will detect a difference assuming that there really is a difference to be detected. (there are many computer programs that can help you)         Randomisation simply means drawing random sanmples for study from the wider population of all the possible individuals that could be in your sample. Proper randomisation means that any individual experimental subject has the same chance of finding itself in each experimental group.      The power of an expeiment will be affected by three main things: the effect size, the amount of random variation and the number of replicates.      Chapter 4 Different experimental designs      The control group must be that it differs from the treatment group in no way except for the treatment being tested.      A blind procedure is one in which the person measuring experimental subjects has no knowledge of which experimental manipulation they have experienced or which treatment group they belong to.   In experiments with humans, we may use a double-blinded procedure in which the experimental subjects too are kept ignorant of which treatment group they belong to.   The procedures are design to remove the perception that unconscious bias might taint the results of a study.   后面讲的paired-design, cross-over design, split-plot design就不如直接看统计书了。      Chapter 5 Taking measures      Calibrate your measuring instruments(including human observers.)   Adopt clear definitions to reduce subjective decision-making during measurement taking.   Watch out for observer drift, intra-observaer variability and inter-observer variability.   Watch out for observer effects, where measuring a system influence its behaviour.      Recording data effectively is a skill that you must acquire.       1. Don't try and record too much information at once;    2. Beware of shorthand codes.    3. Keep more than one copy of your data.    4. Write out your experimental protocol formally and in detail, and keep a detailed field journal or lab work.    5. Don't overwork.      Chapter 6 Final thoughts
个人分类: 科研笔记|322 次阅读|0 个评论
Design Expert V7.1与响应面优化法
wangshilei 2009-12-14 17:16
在Design Expert V7.1中进行实验设计和数据处理,具体效果如何,参见: Design-Expert软件在响应面优化法中的应用(图片) http://bbs.sciencenet.cn/showtopic-73785.aspx 因为博客的附件没有论坛里大,就放到论坛里了。 里面是个人理解,仅供参考! 2010.1.27上传附件,见下面,方便下载: 王世磊-Design-Expert软件在响应面优化法中的应用(外发).pdf
个人分类: Design-experiment软件学习系列|8444 次阅读|1 个评论
[转载]How to Design Effective Experiments for an Economics Class
xiaoyanbabe 2009-10-7 13:54
Most economic's courses are filled with explanations like the one above. This article will dicuss hand's on activities instructor's can use. This article will discuss some successful hand' s on economic's experiments I have used in my undergraduate courses as well as guidelines for designing a successful economic's experiment to be used for demonstration in college classroom, boardroom, or other teaching environment. Instructions Things You'll Need: Creative Mind Something to sketch out your ideas Group of non-economists to test a designed experiment to ensure success. (If applicable i.e. you designed a new experiment and are not sure if it will work.) Step 1 Guidelines to Follow. 1. Experiments should be quick, simple and timely. I have found that one receives the best results after a concept has been explained and the experiment is used to reinforce the material. Using an experiment to introduce an idea may confuse students and take much more time since there will be a lengthy discussion about the concept and then the rules of the game. It is best to explain the concept and use the experiment to follow up the lecture. Experiments need to be conducted on the same day the concept is introduced. Holding an experiment after the fact results in having to go through another explanation and may not flow with current lecture material. 2. Rules and the payoff you desire. Make sure these are compatible. If one has constructed a poorly thought out experiment the rules used will result in payoffs but not necessarily the ones you wanted. 3. Make sure you test the experiment on non-economists before conducting the experiment to assure that the outcome is the one that you are going to get. Undergraduates do not always look at the simple payoff matrix or result as their sole goal. Fairness or class social status may play a role in outcomes that are not modeled by the game. Well constructed games should work to minimize this. 4. Incentives. Make sure that there are adequate incentives to encourage participation. Step 2 Sample experiment 1 Concept: Diminishing marginal productivity Experiment: Popping Popcorn I have conducted this experiment a couple of different ways. The simplest way is to use a microwave. I found myself teaching economics in a physics lab and had one available. Alternatively one can use a hot plate and a disposable metal pan of popcorn (these are sold at most supermarkets next to the microwavable popcorn). The basic idea is that if one input is fixed as more and more of the other inputs are added total productivity goes up but at a decreasing rate. As the popcorn pops our productivity (popped corn) increases but is going to increase at a slower rate until it stops popping altogether. Here the capital good is fixed (metal pan, microwave or hotplate and kernels) while labor and other inputs such as electricity are variable. Allowing students to eat the popcorn afterwards also wins some instructor brownie points. Step 3 Sample experiment 2 Concept: Diminishing marginal utility Experiment: Eating bite size snickers bars Purchase a large bag of bite sized snickers. Have a student volunteer come to the front of the classroom. Next offer them one snicker's bite sized bar at a time and then ask them to rate their satisfaction after each snicker's bar is eaten on a scale of 1 to 10. Very soon the ratings of satisfaction will start to go down which demonstrates diminishing marginal utility. Step 4 Sample experiment 3 Concept: Tragedy of the commons Experiment: Collecting change from the communal coffers For this experiment I draw one large circle on a desk for each group and two smaller circles on either side. Each group is divided up into groups of two that will each take their turn at collecting change using one finger to pull one item of change from the large circle to their respective smaller circle. Everyone is told that at the end of the timed round (30 seconds is plenty of time) 10% of the remaining value of the change left in the large circle will be added. One dollar in various small domination change is placed in the large circle and the first group is allowed to start at the signal I give them. Of course the players in the first group collect all the change from the large circle and there is nothing left to gain any interest for the second group to collect. This demonstrates the tragedy of over harvesting a common resource which is rival but non-excludable.
个人分类: 未分类|3722 次阅读|0 个评论
How to Design Programs
huangfuqiang 2009-7-9 12:17
The Book the complete text Problem Sets additional problem sets not found in the book Companion hints on how to use DrScheme Teachpacks if you encounter bugs in your Teachpacks Known Mistakes known typos and mistakes DrScheme programming environment TeachScheme! our educational outreach effort
个人分类: 计算机软件理论与工程|3546 次阅读|0 个评论

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