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[转载]Nature Structural & Molecular Biology Contents: June 2010 Volume #17 pp 641
xupeiyang 2010-6-5 06:27
NATURE STRUCTURAL MOLECULAR BIOLOGY June 2010 Volume 17 Number 6, pp 641 - 778 Visit Nature Structural Molecular Biology online to browse the journal. Now available at http://links.ealert.nature.com/ctt?kn=103m=34950080r=NDU1MzI2NDEwMAS2b=2j=NzUwNjE5MjQS1mt=1rt=0 Please note that you need to be a subscriber to enjoy full text access to Nature Structural Molecular Biology online. To purchase a subscription, please visit: http://links.ealert.nature.com/ctt?kn=69m=34950080r=NDU1MzI2NDEwMAS2b=2j=NzUwNjE5MjQS1mt=1rt=0 Alternatively, to recommend a subscription to your library, please visit http://links.ealert.nature.com/ctt?kn=28m=34950080r=NDU1MzI2NDEwMAS2b=2j=NzUwNjE5MjQS1mt=1rt=0
个人分类: 信息资源|1877 次阅读|0 个评论
[转载]Nature Cell Biology contents: June 2010 Volume 12 Number 6, pp 521 - 625
xupeiyang 2010-6-2 07:16
NATURE CELL BIOLOGY June 2010 Volume 12 Number 6, pp 521 - 625 Visit Nature Cell Biology online to browse the journal. Now available at http://links.ealert.nature.com/ctt?kn=94m=34937704r=NDU1MzI2NDA5NgS2b=2j=NzQ4NzMzNTUS1mt=1rt=0 Please note that you need to be a subscriber to enjoy full text access to Nature Cell Biology online. To purchase a subscription, please visit: http://links.ealert.nature.com/ctt?kn=19m=34937704r=NDU1MzI2NDA5NgS2b=2j=NzQ4NzMzNTUS1mt=1rt=0 Alternatively, to recommend a subscription to your library, please visit http://links.ealert.nature.com/ctt?kn=135m=34937704r=NDU1MzI2NDA5NgS2b=2j=NzQ4NzMzNTUS1mt=1rt=0
个人分类: 信息资源|1489 次阅读|0 个评论
[转载]Nature Reviews Molecular Cell Biology contents June 2010 Volume 11 Number 6
xupeiyang 2010-5-25 06:22
NATURE REVIEWS MOLECULAR CELL BIOLOGY June 2010 Volume 11 Number 6 Visit Nature Reviews Molecular Cell Biology online to browse the journal. Now available at http://links.ealert.nature.com/ctt?kn=11m=34914366r=NDU1MzI2NDEwOAS2b=2j=NzQ0MjE0MjES1mt=1rt=0 Please note that you need to be a subscriber to enjoy full text access to Nature Reviews Molecular Cell Biology online. To purchase a subscription, please visit: http://links.ealert.nature.com/ctt?kn=35m=34914366r=NDU1MzI2NDEwOAS2b=2j=NzQ0MjE0MjES1mt=1rt=0 Alternatively, to recommend a subscription to your library, please visit http://links.ealert.nature.com/ctt?kn=70m=34914366r=NDU1MzI2NDEwOAS2b=2j=NzQ0MjE0MjES1mt=1rt=0 ********************************************************************* Nature Reviews Molecular Cell Biology Impact Factor: 35.423* *2008 Journal Citation Report (Thomson Reuters, 2009)
个人分类: 信息资源|1918 次阅读|0 个评论
Nature Chemical Biology Contents: June 2010 Volume 6 pp. 385 - 470
xupeiyang 2010-5-18 09:46
应读者要求，我选择和推荐的期刊信息。许培扬 NATURE CHEMICAL BIOLOGY June 2010 Volume 6 Number 6, pp 385 - 470 Visit Nature Chemical Biology online to browse the journal. Now available at http://links.ealert.nature.com/ctt?kn=56m=34892649r=NDU1MzI2NDE1NgS2b=2j=NzM5NTIzOTIS1mt=1rt=0 Please note that you need to be a subscriber to enjoy full text access to Nature Chemical Biology online. To purchase a subscription, please visit: http://links.ealert.nature.com/ctt?kn=79m=34892649r=NDU1MzI2NDE1NgS2b=2j=NzM5NTIzOTIS1mt=1rt=0 Alternatively, to recommend a subscription to your library, please visit http://links.ealert.nature.com/ctt?kn=116m=34892649r=NDU1MzI2NDE1NgS2b=2j=NzM5NTIzOTIS1mt=1rt=0
个人分类: 信息资源|1721 次阅读|0 个评论
Molecular Systems Biology - New articles published 11 May 2010
xupeiyang 2010-5-13 07:32
MOLECULAR SYSTEMS BIOLOGY 11 May 2010 ********************************************************************** What if you could use 25 ng or less of total RNA for labeling in an expression experiment? Agilent announces the launch of the new Low Input Quick Amp Labeling Kit. Obtain the same high sensitivity performance you expect, but conserve your precious sample, all at the same time. Find out how to use this new product at http://links.ealert.nature.com/ctt?kn=11m=34876418r=Mzg0ODUxNzc1NQS2b=2j=NzM1ODkwMjkS1mt=1rt=0
个人分类: 开放获取|1892 次阅读|0 个评论
研究热点分析：网络生物学 Network biology 1938 - 2010
xupeiyang 2010-5-12 10:59
http://www.gopubmed.org/web/gopubmed/2?WEB01wk71quvwwbp3I5rIafI00h01000j100200010 13,628 documents semantically analyzed 后基因组生物医学研究目标的关键是系统地编目所有分子和在一个活细胞内它们的交互作用。因此显然需要理解在孤立和当被其他细胞环绕时这些分子状态和它们如何相互作用决定了这个巨大的复杂机制。快速发展的 网络生物学 预示了 细胞网络是被普遍的规律控制的 ,并且提议了一个新的可能潜在变革在21世纪的 生物学和疾病病理学的观点 的 概念框架 。 绝大多数生物特性起因于' 细胞内众多委托人 ，例如蛋白质、DNA、RNA和小分子之间的复杂相互作用。因此在21世纪生物学的关键挑战是了 解复杂细胞内的' 交互网络结构 和 动力学 ，这些能为活细胞的结构和功能作出贡献。 随着广泛利用微阵列,高通量的数据收集技术的发展能够同时并发地研究细胞成分的状态。另外, 新技术平台 ,例如蛋白质片（PROTEIN CHIPS）或半自动化的酶两-杂交筛选（YEAST TWO-HYBRID SCREENS）,都 有助于决定这些分子如何和何时与其他作用 。 从这些交互作用的总合中已浮现了 多种交互网络类型 (包括蛋白质-蛋白质交互、代谢作用、信号、和转录-调控网络)。这些网络无一是独立的，而是形成了一个大网络中的网络（network of networks）， 这些网络对细胞的行为负责 。当代生物学的主流挑战是为了控制细胞的行为要绘制，理解和以可量化术语条目（terms）模拟各种网络的拓扑性质和动力学性质，要驾驭 有理论 的和 有试验 的 综合程序 。 遵循在过去几年迅速发展的,统治着各种复杂的技术网络和社会网络形成和进化的复杂网络理论的这条路，会有助于揭露网络的组织原则。这个研究现在已经对细胞生物学产生了重要影响。它已经引导了更大程度地共享其他复杂系统的底层结构(例如因特网、计算机芯片和社会)来实现细胞内分子交互网络的底层结构。这个意想不到的普遍性指出了相似法则可能统治了自然界中绝大多数的复杂网络,这样就能够允许用来自非生物学系统的更大程度和更好映射的专门技术来特征化内部交织在一起地统治着细胞功能的关联。 1 2 3 Top Years Publications 2009 1,951 2008 1,593 2007 1,421 2006 1,226 2005 1,017 2004 982 2010 721 2003 691 2002 613 2001 511 2000 393 1999 304 1998 283 1997 258 1995 242 1996 219 1993 199 1994 195 1992 168 1990 123 1 2 3 1 2 3 ... 6 Top Countries Publications USA 5,850 Germany 1,098 United Kingdom 858 Canada 733 Japan 571 Italy 402 China 374 France 295 Spain 289 Netherlands 270 Switzerland 209 Sweden 203 Australia 196 Israel 164 India 127 Singapore 126 South Korea 122 Belgium 119 Taiwan 108 Denmark 104 1 2 3 ... 6 1 2 3 ... 51 Top Cities Publications Toronto 384 New York 328 Boston 285 Heidelberg 234 Bethesda 226 Cambridge, USA 210 London 192 Chicago 160 San Diego 156 Pasadena, CA, USA 152 Berkeley 152 Cambridge 142 Philadelphia 142 Singapur 126 Beijing 125 Los Angeles 124 Tokyo 122 Seattle 121 Houston 115 Berlin 112 1 2 3 ... 51 1 2 3 ... 108 Top Journals Publications J Biol Chem 338 Bioinformatics 299 Bmc Bioinformatics 260 P Natl Acad Sci Usa 258 J Cell Biol 223 J Cell Sci 165 Nucleic Acids Res 156 Plos One 154 Mol Biol Cell 147 J Mol Biol 138 Science 137 Proc Natl Acad Sci U S A 131 Dev Biol 130 Plos Comput Biol 129 Nature 128 Bmc Syst Biol 126 Development 110 J Neurosci 108 Biochemistry-us 102 Cell 99 1 2 3 ... 108 1 2 3 ... 1198 Top Terms Publications Animals 6,323 Proteins 5,518 Humans 5,263 Genes 4,316 Biology 2,409 Computational Biology 2,107 signal transduction 2,066 Models, Biological 1,848 Genomics 1,749 Signal Transduction 1,730 Mice 1,707 Genome 1,654 Membranes 1,600 membrane 1,596 gene expression 1,475 Gene Expression 1,463 Algorithms 1,380 Mutation 1,372 Gene Regulatory Networks 1,337 Metabolism 1,303 1 2 3 ... 1198 1 2 3 ... 2436 Top Authors Publications Palsson B 44 Davidson E 44 Simons K 39 Bonifacino J 34 Marder E 27 Ramrez J 25 Hong W 23 Dick J 22 Staehelin L 21 Katoh M 20 Bahar I 20 Calabrese R 20 Borisy G 20 Gerstein M 18 Casadio R 18 Fariselli P 18 Westerhoff H 17 Fuchs E 17 Alon U 17 Goldman R 17 1 2 3 ... 2436
个人分类: 热点前沿|2085 次阅读|0 个评论
[转载] Nature WEB FOCUS Synthetic systems biology
热度 1 xupeiyang 2010-3-6 10:30
请连接 http://www.nature.com/nature/focus/syntheticsytemsbiology/ Synthetic systems biology In this focus Editorial News Current Research Archive Podcast Video Links Synthetic biology goes beyond classic genetic engineering as it attempts to engineer living systems to perform new functions not found in nature. Ten years ago this week, Nature published a pair of seminal papers that stimulated 'systems biology' thinking in the field. This web focus gathers these two papers together with papers more recently published by Nature in the same spirit. Image: Tal Danino, Octavio Mondragn-Palomino, Lev Tsimring Jeff Hasty Top of page Editorial Editorial Ten years of synergy Free access Nature 463 , 269270 (21 January 2010) :10.1038/463269b :10.1038/463269b Full Text | Top of page News News Feature Bioengineering: Five hard truths for synthetic biology