原帖地址: http://www.mitbbs.com/article_t1/WaterWorld/2191293_0_1.html 新浪微博有人爆料,诺贝尔奖获得者Sudhof老婆是踹了中国原配找美国老头的中国 裔女留学生: @walnut姐姐:他Lp和她的前lg是国内大学同学双飞,后来俩人经过奋斗成为某校ap ,那时她的前lg给她挂了很多文章。后来她搭上了sudhof,离婚又结婚又生女,然后就迅 速得了某个行内特大的奖得了tenure,她前lg现在还是个ap,一个女人是怎么成功的 我解说一下,今年的诺贝尔生物及医学奖奖获得者Sudhof,他的老婆叫做陈路,是 无锡人,毕业于无锡二中(今辅仁中学)、无锡一小、无锡机关幼儿园。 陈路1989年考入中科大,后来去美国留学,她的原配老公也是中国人,叫做包绍文。 这是她原配老公的网站:http://baolab.org 她的原配老公包绍文是很牛的人,发CNS的主(CNS是生物医学领域最高的三个期刊 的首字母),给了她很大的帮助,给她挂了很多论文。 后来因为陈路要来加州大学伯克利分校读书,他老公放弃找正式教职的机会,跟着 她一起来伯克利陪她读书,找了个non-tenure track(临时工性质的非正式教职)。 她老公给他帮了极大的忙,有人查了她的论文,水木社区网友lauv查到了一堆论文 都是夫妻档,疑似老公帮忙的。 1. Chen C, Kano M, Abeliovich A, Chen L, Bao S, Kim JJ, Hashimoto K, Thompson RF and Tonegawa S. (1995). Impaired motor coordinationcorrelates with persistent multiple climbing fiber innervation inPKC-gama mutant mice. Cell, 83, 1233-1242. 2. Chen L, Bao S,Kim JJ, Lockard J and Thompson RF. (1996). Impaired classical eyeblinkconditioning in cerebellar lesion and Purkinje cell degeneration mutantmice. Journal of Neuroscience, 16, 2829-2838. 3. Shibuki K, Gomi H, Chen L, Bao S, Kim JJ, Wakatsuki H, Fujisaki T, Fujimoto K, Ikeda T, Chen C, Thompson RF and Itohara S. (1996).Deficient cerebellar long-term depression, impaired eyeblinkconditioning and normal motor coordination in GFAP mutant mice. Neuron,16, 587-599. 4. Thompson RF, Bao S, Chen L, Cipriano B,Grethe JS, Kim JJ, Thompson JK , Tracy J, Weninger MS and Krupa DJ.(1996). Associative learning. In: The Cerebellum and Cognition,151-189.(Eds. J. D. Schmahmann), Academic Press, New York. 5. KimJJ, Chen L, Bao S, Sun W and Thompson RF. (1996). Genetic dissection ofthe cerebellar circuitry involved in classical eyeblink conditioning.In: Gene Targeting and New Development in Neurobiology, 3-15. ( Eds. S.Nakanishi et al.), Japan Scientific Societies Press, Tokyo. 6. Kim JJ, Shih JC, Chen K, Chen L, Bao S, Maren S, Anagnostaras SG, Fanselow MS, Maeyer ED, Seif I and Thompson RF. (1997). Selectiveenhancement of emotional, but not motor learning in monoamine oxidaseA-deficient mice. PNAS, 94, 5929-5933. 7. Bao S, Chen L andThompson RF. (1998). Classical eyeblink conditioning in two strains ofmice: conditioned responses, sensitization and spontaneous eyeblinks.Behavioral Neuroscience, 112, 714-718. 8. Bao S, Chen L,Qiao X and Thompson RF. (1998). Impaired classical eyeblink conditioningin waggler, a mutant mouse with localized BDNF deficit in thecerebellum. Learning and Memory, 5, 355-364. 9. Qiao X, ChenL, Gao H, Bao S, Hefti H, Thompson RF and Knusel B. (1998 ). Cerebellarbrain-derived neurotrophic factor-TrkB defect associated with impairmentof eyeblink conditioning in stargazer mutant mice. Journal ofNeuroscience, 18, 6990-6999. 10. Chen L, Bao S and ThompsonRF. (1999). Bilateral lesions of the interpositus nucleus completelyprevent eyeblink conditioning in Purkinje cell degeneration mutant mice.Behavioral Neuroscience, 113, 204-210. 11. Bao S, Chen L,Qiao X and Thompson RF. (1999). Transgenic brain- derived neurotrophicfactor modulates a developing cerebellar inhibitory synapse. Learningand Memory, 6, 276-283. 12. Chen L, Bao S, Qiao X andThompson RF. (1999). Impaired cerebellar synapse maturation in thewaggler, a mutant mouse with a disrupted neuronal calcium channel gammasubunit. PNAS, 96, 12132-12137. 13. Bao S, Chen L andThompson RF. (2000). Learning- and cerebellum- dependent neuronalactivity in the lateral pontine nucleus. Behavioral Neuroscience, 114,254-61. 14. Bao S, Chen L, Kim JJ and Thompson RF. (2002).Cerebellar cortical inhibition and classical eyeblink conditioning.PNAS, 99, 1592-1597. 15. Bao S and Chen L. (2002). Geneticsubstrates of memory: cerebellum. In Learning and Memory: MacmillanPsychology Reference Series. Volume 2. (Ed. Byrne, J. H.). MacMillan,Farmington Hills. 她拿到那个麦克阿瑟天才奖,也不是什么功绩,一方面靠老公给挂名的论文,另一 方面水木社区网友conti说:在berkeley的都知道,macarthur foundation专门favor MCB的 女faculty,基本只要有还过得去的新进的女PI,稳给,这些年多少了 从Lu Chen,到Nicole King,到Lin He 陈路被包绍文捧起来后,搭上了sudhof这个大牛。 她飞速地把包绍文踹掉了,嫁给了sudhof这个老头。sudhof比她大17岁(sudhof是 1955年出生的,陈路是1972年出生的)。 sudhof似乎也是和黄脸婆离婚和她结婚的,具体情况不清楚。 嫁给了sudhof这个老头后,陈路迅速发迹了,很快就拿到了副教授的位置。 可怜她老公现在还是临时性的教职。 现在无锡和中科大开始得意了,诺贝尔奖获得者是无锡的女婿,中科大的女婿。 尤其是无锡,高兴坏了。 另外,饶毅很早以前就曾经鄙视过陈路,现在已经有人翻出饶毅当年的鄙视话语, 洋洋得意地抽饶毅。
老婆第一篇SCI文章正式发表于《The Journal of Immunology》上,影响因子为5.788,热烈祝贺! Mitogen-Activated Protein Kinase Kinase 3 Potentiates Chlamydia HSP60-Induced Inflammatory Response through Distinct Activation of NF-kB ( pdf ) Chlamydia pneumonia (C. pneumonia) remains one of the leading causes of bacterial pneumonia and has been implicated in the pathogenesis of some inflammation-related diseases, such as asthma, chronic obstructive pulmonary disease, and vascular diseases.Heat shock protein 60 is one of the pathogenic components of C. pneumonia that is closely associated with the inflammatory disorders. However, the molecular basis for the immunopathologic property of chlamydial heat shock protein (cHSP60) has not been elucidated. In this article, we report that MAPK kinase 3 (MKK3) is essential for cHSP60-induced lung inflammation,because MKK3-knockout mice displayed significantly reduced lung neutrophil accumulation and decreased production of proin- flammatory mediators, correlating with the alleviated inflammatory response in lung tissues. Mechanistically, p38 kinase was selectively activated by MKK3 and activated NF-kB by stimulating the nuclear kinase, mitogen- and stress-activated protein kinase 1. The specific knockdown of mitogen- and stress-activated protein kinase 1 in macrophages resulted in a defective phosphorylation of NF-kB/RelA at Ser276 but had no apparent effect on RelA translocation. Furthermore, TGF-b–activated kinase 1 was found to relay the signal to MKK3 from TLR4, the major receptor that sensed cHSP60 in the initiation of the inflammatory response. Thus, we establish a critical role for MKK3 signaling in cHSP60 pathology and suggest a novel mechanism underlying C. pneumonia–associated inflammatory disorders. http://www.jimmunol.org/content/early/2013/05/31/jimmunol.1300481
那些怕老婆的男人们 ( Henpecked men) 什么样算是怕老婆? 如果一个家庭里的男人不得不容忍一个女人改变自己的人格和其所信奉的生活哲学,那么这样的男人就是怕老婆的男人! If a man allows a woman to not let him be him and change his personality and his philosophy of life then he can be considered henpecked. 怕老婆怕到什么程度? 女人见男人不听从指挥,就上下其手,大扇男人耳光! I have a brother in law who is so hen pecked I saw his ex wife slap him across the face like a child when he didn't do what she asked of him. 为什么怕老婆? 有人认为在一个家庭里,比男人挣钱多的女人会自动占据主导的位置,那么这个家庭的男人自然就成为从属角色。怕老婆。 Depends on who is making the most money in the relationship. Money trumps all! If the man is not bringing home the income to provide for his family then women have no other option but to lead. That might hurt but it's the truth. 男人怕老婆?没影儿事!那是“爱”老婆! There is nothing sexier than a man who is strong enough to be soft with his family. that's not hen-pecked, that's love. 你怕老婆?还是爱老婆? 我觉得这是您自己的事情!别人无权干涉你的内政! 但你是否怕老婆?还是爱老婆?关键还是要你自问:我是不是觉得不是那么心甘情愿?还是你觉得这是周瑜打黄盖的事情?
芒果台的宫廷青春大戏宫·锁珠帘正在热播中,好火啊 ,收视率高居各台之首,老婆大人被TA迷得整晚抱着电视机不放手 ,吸引的连女儿也迷上TA了。 想想自己不能总是处于被边缘化,孤立无援的境地 ,因此我也毅然加入了观看宫·锁珠帘的光荣行动中了。不看也罢, 陪着老婆和女儿看了看之后,倒还真的被吸引住了 ,虽是古装打扮,但却帅哥美女无数;既有功夫打斗,又有柔情缠绵;勾心斗角,阴谋诡计中还颇有几分乐趣! 呵呵,不错,这已经陆陆续续看了很多集,里面的聪明女子真不少,她们不光貌美如花,而且勾心斗角,使绊子设套,都是高手;但是结果却发现, 像怜儿这样,没心没肺,傻傻愣愣的倒是活的最幸福,并且最终还能得到成功。 想想以前陪女儿和老婆看的《功夫熊猫》,似乎也是这样的,熊猫阿宝,最是没心没肺,傻傻愣愣,整天因为煮不好面条被妈妈臭骂,却没想到最终学会了最为高深莫测的功夫。 还记得,最早时候看《阿甘正传》,阿甘的名言是:Life is just like a box of chocolates, you neverknowwhat you're gonna get.呵呵,阿甘就是这样一个人,别人都认为他是最傻的,是最没出息的,却没想到他、他是一个真正伟大的人。 阿甘,阿宝,怜儿,他们其实本质上都是一类人......
科学网上的博士们,你们其实可以不娶老婆的。不信?你们看看这三位天才都没有娶老婆。 1、 尼古拉·特斯拉 (Nikola Tesla 1856-1943),他的科学创作超前了同期水平300年,甚至超越1000年以上。而且他还能用落后一百年的设备去提前展现出一百年后的成果表现,简直是不可思议。一般人能了解到他的作品全是四十岁以前,只有实证派科学家才有机会涉猎到他四十岁以后的少数作品。他晚年四十五年间的作品全部被列入绝对机密,至今仍无从得知细节。由于他的手稿及绝密数据必定被永久封存在地窖,势必如同达文西当年的情况,直到二百年后的人类才能开始慢慢看到资料。但是,吾人在此先将他定位完毕,不必如同达文西的悲惨命运得等待五百年后才能重新被定位。 2、 李奥纳多·达文西 (Leonardo di ser Piero da Vinci 1452-1519),他的科学创作超前了同期水平200年到500年。一般人以为他是艺术家,因为他创作的《蒙娜莉萨》、《最后的晚餐》很有名气。事实上达文西是人类史上非常伟大的科学家,且他是典型的实证派,不是理论派。他的艺术天份正如同尼古拉·特斯拉具备极高的音乐造诣,差异在于尼古拉·特斯拉在音乐及诗词这方面的极高艺术,也被美国政府列入绝对机密,没有在民间流传,其中也包含了哲学都被列入绝密。诸如尼古拉·特斯拉与达文西此类伟大的天才科学家,活在同时代的人们是无福洞悉其智慧的,只能留给数百年后的人类去享用,面向此类怪异的现象,从三千年前的古文明到今日依旧不变,正是「因缘法」的奥妙,「自然演化」的安全机制,不必遗憾。 3、 艾萨克·牛顿 (Sir Isaac Newton 1643-1727),人类史上对科学界贡献最大的人,无疑地就是牛顿。主要在于他的贡献是全面且广泛的,且他在作品方面的治学极其严谨,实为学术典范,无论从低层到高层次的科学界,通通受用无穷。 这三位,无论从艺术还是科学,都称得上大家了,他们都可以不娶老婆,你们为什么不行?既然打算为科学献身,就天天搞科研好了,老婆哪里比得上科研重要?对吧!所以我是鼓励你们不娶老婆,一心科研,为中国科技进步做出小小的牺牲,我相信是值得的。你们都很忙,都是天才,天才其实不需要老婆的。 顺便 解释一下:特斯拉就是传说中的“人造地震”之父,物理学家,发明家, 达文西就是达芬奇,牛顿还是那个牛顿。 相关博文 男博士,还要不要上非诚勿扰