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Hepatology2013年最受关注文章
WileyChina 2014-2-25 16:41
美国肝病研究学会( American Association for the Study of Liver Diseases ) 官方期刊 Hepatology 对其 2013 年发表的文章进行了回顾总结,向读者推荐其中按引用次数排名前 10 位的文章和按全文下载次数排名前 10 位的文章,相关领域的朋友值得关注一下: 一、按引用次数排名前10位 1. Global Epidemiology of Hepatitis C Virus Infection: New Estimates of Age-Specific Antibody to HCV Seroprevalence Hanafiah, Khayriyyah Mohd; Groeger, Justina; Flaxman, Abraham D.; et al. Volume 57, Issue 4 2. Characterization of Gut Microbiomes in Nonalcoholic Steatohepatitis (NASH) Patients: A Connection Between Endogenous Alcohol and NASH Zhu, Lixin; Baker, Susan S.; Gill, Chelsea; et al. Volume 57, Issue 2 3. IL28B Polymorphisms Predict Interferon-related Hepatitis B Surface Antigen Seroclearance in Genotype D Hepatitis B e Antigen–negative Patients with Chronic Hepatitis B Lampertico, Pietro; Vigano, Mauro; Cheroni, Cristina; et al. Volume 57, Issue 3 4. Anemia During Treatment with Peginterferon Alfa-2b/ribavirin and Boceprevir: Analysis from the Serine Protease Inhibitor Therapy 2 (SPRINT-2) trial Sulkowski, Mark S.; Poordad, Fred; Manns, Michael P.; et al. Volume 57, Issue 3 5. Association of AKI With Mortality and Complications in Hospitalized Patients With Cirrhosis Belcher, Justin M.; Garcia-Tsao, Guadalupe; Sanyal, Arun J.; et al. Volume 57, Issue 2 点击查看完整列表 二、按全文下载次数排名前10位 1. Introduction to the revised American Association for the Study of Liver Diseases Practice Guideline management of adult patients with ascites due to cirrhosis 2012 Bruce A. Runyon Volume 57, Issue 4 2. The nutritional management of hepatic encephalopathy in patients with cirrhosis: International society for hepatic encephalopathy and nitrogen metabolism consensus Piero Amodio, Chantal Bemeur, Roger Butterworth, Juan Cordoba, Akinobu Kato, Sara Montagnese, Misael Uribe, Hendrik Vilstrup and Marsha Y. Morgan Volume 58, Issue 1 3. Long noncoding RNAs associated with liver regeneration 1 accelerates hepatocyte proliferation during liver regeneration by activating Wnt/β-Catenin signaling Dan Xu, Fu Yang, Ji-hang Yuan, Ling Zhang, Hai-shan Bi, Chuan-chuan Zhou, Feng Liu, Fang Wang and Shu-han Sun Volume 58, Issue 2 4. Long-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection Tetsuya Hosaka, Fumitaka Suzuki, Masahiro Kobayashi, Yuya Seko, Yusuke Kawamura, Hitomi Sezaki, Norio Akuta, Yoshiyuki Suzuki, Satoshi Saitoh, Yasuji Arase, Kenji Ikeda, Mariko Kobayashi and Hiromitsu Kumada Volume 58, Issue 1 5. Efficacy of tenofovir disoproxil fumarate at 240 weeks in patients with chronic hepatitis B with high baseline viral load Stuart C. Gordon, Zahary Krastev, Andrzej Horban, Jörg Petersen, Jan Sperl, Phillip Dinh, Eduardo B. Martins, Leland J. Yee, John F. Flaherty, Kathryn M. Kitrinos, Vinod K. Rustgi and Patrick Marcellin Volume 58, Issue 2 点击查看完整列表
个人分类: Health Science|2238 次阅读|0 个评论
Liver International特刊:第六届巴黎肝炎大会论文集
WileyChina 2013-8-23 10:44
第六届巴黎肝炎大会于 2013 年 1 月成功举行,来自全球 60 多个国家的 1000 多位专家聚集在巴黎,带来了如何治疗和管理乙型或丙型肝炎病人的最新信息,并分享了最新的数据和临床应用进展。 每年都有许多新药问世,有许多新的治疗手段诞生,如此飞速的发展使得治疗和管理肝炎携带病人变得愈发复杂和个性化。因此,让临床从业者及时了解最新发展动态对于他们更有效地治疗和管理病人非常重要。 为了配合此次大会,期刊 LiverInternational 特意出版了一期增刊,收录了许多综述型文章,原始内容均来自大会上专家们分享的最新临床研究信息,是当前全球最新的与治疗乙型和丙型肝炎相关的临床研究。 以下为部分文章列表,感兴趣的朋友请访问 http://onlinelibrary.wiley.com/doi/10.1111/liv.2012.33.issue-s1/issuetoc 阅读完整刊物,所有文章都可以免费阅读。 Treatment ofviral hepatitis: a new era (pages 1–2) Patrick Marcellin andTarik Asselah Article first publishedonline: 3 JAN 2013 | DOI: 10.1111/liv.12086 Abstract Full Article (HTML) PDF(92K) References Optimaltreatment with boceprevir for chronic HCV infection (pages 14–22) Benjamin Maasoumy andMichael P. Manns Article first publishedonline: 3 JAN 2013 | DOI: 10.1111/liv.12070 Abstract Full Article(HTML) PDF(213K) References How to optimizeHCV therapy in genotype 1 patients: predictors of response (pages 23–29) Salvatore Petta andAntonio Craxì Article first publishedonline: 3 JAN 2013 | DOI: 10.1111/liv.12053 Abstract Full Article(HTML) PDF(173K) References HCV therapy inHIV-infected patients (pages 63–67) Mark S. Sulkowski Article first publishedonline: 3 JAN 2013 | DOI: 10.1111/liv.12082 Abstract Full Article (HTML) PDF(125K) References New therapeuticstrategies in HCV: second-generation protease inhibitors (pages 80–84) Virginia C. Clark, JoyA. Peter and David R. Nelson Article first publishedonline: 3 JAN 2013 | DOI: 10.1111/liv.12061 Abstract Full Article (HTML) PDF(116K) References Optimal managementof chronic hepatitis B patients with treatment failure and antiviral drugresistance (pages 116–124) Fabien Zoulim andStephen Locarnini Article first publishedonline: 3 JAN 2013 | DOI: 10.1111/liv.12069 Abstract Full Article (HTML) PDF(162K) References Why do I treatHBeAg-positive chronic hepatitis B patients with a Nucleoside analogue (pages133–136) Hong Ma and Jidong Jia Article first publishedonline: 3 JAN 2013 | DOI: 10.1111/liv.12065 Abstract Full Article (HTML) PDF(116K) References Optimalmanagement of HBV infection during pregnancy (pages 188–194) Teerha Piratvisuth Article first publishedonline: 3 JAN 2013 | DOI: 10.1111/liv.12060 Abstract Full Article (HTML) PDF(189K) References Hope for theeradication of HCV worldwide (pages 198–199) Jean-François Delfraissy Article first publishedonline: 3 JAN 2013 | DOI: 10.1111/liv.12077 Abstract Full Article (HTML) PDF(97K)
个人分类: Health Science|2574 次阅读|0 个评论
Wiley论文被引次数排名Top5—肝病学(2010-2012年)
WileyChina 2013-1-15 17:09
我们将 2010 年至 2012 年发表在 Wiley 肝病学期刊上的论文,按照 ISI 被引频次排名,得到排名前五的文章如下: 1. ManagementofHepatocellularCarcinoma:AnUpdate 作者: Bruix,Jordi;Sherman,Morris 所属期刊: HEPATOLOGY ISI 被引频次: 261 原文地址: http://onlinelibrary.wiley.com/doi/10.1002/hep.24199/abstract 摘要: SincethepublicationoftheAmericanAssociationfortheStudyofLiverDiseases(AASLD)practiceguidelinesonthemanagementofhepatocellularcarcinoma(HCC)in2005,newinformationhasemergedthatrequiresthattheguidelinesbeupdated.ThefullversionofthenewguidelinesisavailableontheAASLDWebsiteat http://www.aasld.org/practiceguidelines/Documents/Bookmarkedpercnt;20Practice%20Guidelines/HCCUpdate2010.pdf .Here,webrieflydescribeonlyneworchangedrecommendations. 2. ObesityandNonalcoholicFattyLiverDisease:Biochemical,Metabolic,andClinicalImplications 作者: Fabbrini,Elisa;Sullivan,Shelby;Klein,Samuel 所属期刊: HEPATOLOGY ISI 被引频次: 138 原文地址: http://onlinelibrary.wiley.com/doi/10.1002/hep.23280/abstract 摘要: Obesityisassociatedwithanincreasedriskofnonalcoholicfattyliverdisease(NAFLD).Steatosis,thehallmarkfeatureofNAFLD,occurswhentherateofhepaticfattyaciduptakefromplasmaanddenovofattyacidsynthesisisgreaterthantherateoffattyacidoxidationandexport(astriglyceridewithinverylow-densitylipoprotein).Therefore,anexcessiveamountofintrahepatictriglyceride(IHTG)representsanimbalancebetweencomplexinteractionsofmetabolicevents.Thepresenceofsteatosisisassociatedwithaconstellationofadversealterationsinglucose,fattyacid,andlipoproteinmetabolism.Itislikelythatabnormalitiesinfattyacidmetabolism,inconjunctionwithadiposetissue,hepatic,andsystemicinflammation,arekeyfactorsinvolvedinthedevelopmentofinsulinresistance,dyslipidemia,andothercardiometabolicriskfactorsassociatedwithNAFLD.However,itisnotclearwhetherNAFLDcausesmetabolicdysfunctionorwhethermetabolicdysfunctionisresponsibleforIHTGaccumulation,orpossiblyboth.UnderstandingtheprecisefactorsinvolvedinthepathogenesisandpathophysiologyofNAFLDwillprovideimportantinsightsintothemechanismsresponsibleforthecardiometaboliccomplicationsofobesity. 3. NonalcoholicFattyLiverDiseaseandHepatocellularCarcinoma:AWeightyConnection 作者: Starley,BradQ.;Calcagno,ChristopherJ.;Harrison,StephenA. 所属期刊: HEPATOLOGY ISI 被引频次: 137 原文地址: http://onlinelibrary.wiley.com/doi/10.1002/hep.23594/abstract 摘要: Hepatocellularcarcinoma(HCC)isacommonanddeadlymalignancythatisincreasinginincidenceindevelopedcountries.TheemergenceofhepatitisCvirus(HCV)accountsforabouthalfofthisincreaseinHCC,althoughtheetiologyofHCCin15%-50%ofnewHCCcasesremainsunclear.Themostcommonformofchronicliverdiseaseindevelopedcountriesisnonalcoholicfattyliverdisease(NAFLD),whichencompassesabroadspectrumofhistopathology.TheprevalenceofNAFLD,includingthemoreaggressivenonalcoholicsteatohepatitis(NASH),isincreasingwiththegrowingepidemicsofdiabetesandobesity.NASHcanprogresstocirrhosisanditsrelatedcomplications.GrowingevidencesuggeststhatNASHaccountsforalargeproportionofidiopathicorcryptogeniccirrhosis,whichisassociatedwiththetypicalriskfactorsforNASH.HCCisarare,althoughimportantcomplicationofNAFLD.DiabetesandobesityhavebeenestablishedasindependentriskfactorsforthedevelopmentofHCC.NewevidencealsosuggeststhathepaticirondepositionincreasestheriskofHCCinNASH-derivedcirrhosis.MultiplecasereportsandcasereviewsofHCCinthesettingofNASHsupporttheassociationsofdiabetesandobesitywiththeriskofHCC,aswellassuggestageandadvancedfibrosisassignificantrisks.InsulinresistanceanditssubsequentinflammatorycascadethatisassociatedwiththedevelopmentofNASHappeartoplayasignificantroleinthecarcinogenesisofHCC.ThecomplicationsofNASH,includingcirrhosisandHCC,areexpectedtoincreasewiththegrowingepidemicofdiabetesandobesity. 4. DiagnosisandManagementofAutoimmuneHepatitis 作者: Manns,MichaelP.;Czaja,AlbertJ.; Gorham,JamesD.; Krawitt,EdwardL.; Mieli-Vergani,Giorgina;Vergani,Diego;Vierling,JohnM. 所属期刊: HEPATOLOGY ISI 被引频次: 114 原文地址: http://onlinelibrary.wiley.com/doi/10.1002/hep.23584/abstract 摘要: Clinicalpracticeguidelinesaredefinedas‘‘systematicallydevelopedstatementstoassistpractitionerandpatientdecisionsaboutappropriateheathcareforspecificclinicalcircumstances.’’(AllreferencesareavailableintheSupportingInformation.)Theseguidelinesonautoimmunehepatitisprovideadata-supportedapproachtothediagnosisandmanagementofthisdisease.Theyarebasedonthefollowing:(1)formalreviewandanalysisoftherecently-publishedworldliteratureonthetopic ;(2)AmericanCollegeofPhysiciansManualforAssessingHealthPracticesandDesigningPracticeGuidelines;(3)guidelinepolicies,includingtheAASLDPolicyontheDevelopmentandUseofPracticeuidelinesandtheAmericanGastroenterologicalAssociationPolicyStatementonGuidelines;and(4)theexperienceoftheauthorsinthespecifiedtopic. 5. HighlyEfficientGenerationofHumanHepatocyte-LikeCellsfromInducedPluripotentStemCells 作者: Si-Tayeb,Karim; Noto,FallonK.; Nagaoka,Masato; Li,Jixuan;Battle,MicheleA.;Duris,Christine;North,PaulaE.;Dalton,Stephen;Duncan,StephenA. 所属期刊: HEPATOLOGY ISI 被引频次: 113 原文地址: http://onlinelibrary.wiley.com/doi/10.1002/hep.23354/abstract 摘要: Thereexistsaworldwideshortageofdonorliversavailablefororthotropiclivertransplantationandhepatocytetransplantationtherapies.Inadditiontotheirtherapeuticpotential,primaryhumanhepatocytesfacilitatethestudyofmolecularandgeneticaspectsofhumanhepaticdiseaseanddevelopmentandprovideaplatformfordrugtoxicityscreensandidentificationofnovelpharmaceuticalswithpotentialtotreatawidearrayofmetabolicdiseases.Thedemandforhumanhepatocytes,therefore,heavilyoutweighstheiravailability.Asanalternativetousingdonorliversasasourceofprimaryhepatocytes,weexploredthepossibilityofgeneratingpatient-specifichumanhepatocytesfrominducedpluripotentstem(iPS)cells.Conclusion:WedemonstratethatmouseiPScellsretainfullpotentialforfetalliverdevelopmentanddescribeaprocedurethatfacilitatestheefficientgenerationofhighlydifferentiatedhumanhepatocyte-likecellsfromiPScellsthatdisplaykeyliverfunctionsandcanintegrateintothehepaticparenchymainvivo.
个人分类: Health Science|2874 次阅读|0 个评论
胃肠病学与肝病学研究优秀国际论文 by F1000 Factor
xupeiyang 2010-8-8 09:17
详细信息见 http://f1000medicine.com/browse/GASTRO 国际医学专家按F1000 Factor评出的胃肠病学与肝病学研究国际优秀论文,你可以选择查阅近一周至近五年发表的优秀论文。 可按以下分类进行检索查阅: Gastroenterology Hepatology Biliary Tract Clinical Nutrition Colon Rectum Disorders of Neurogastroenterology Motility Endoscopy Esophagus Gastrointestinal Cancers Gastrointestinal Infections Inflammatory Bowel Disease Liver Biology Pathobiology Liver Failure Liver Disease Pancreas Small Intestine Stomach Duodenum
个人分类: 肝脏病学|4235 次阅读|0 个评论

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