《自然》杂志预测2011年科研热点 http://news.sciencenet.cn//htmlnews/2011/1/242378.shtm 干细胞研究：整装待发 科学家知道如何将人体细胞重编程为诱导多功能干细胞（iPS cell），并将iPS细胞转化成为其他细胞类型。接下来，从病人体内获取的iPS细胞将更多地应用到医学研究模型、潜在药物的筛选以及为何现存药物只对部分病人有用的研究上。 New year, new science http://www.nature.com/news/2010/101231/full/469012a.html Stem cells: ready for study Researchers have learned how to reprogram people's cells into induced pluripotent stem (iPS) cells, and on from that into other cell types: skin cells can be turned into nerve cells, for example. Patient-derived iPS cells will increasingly be used as models for studying medical conditions particularly those, such as psychiatric disorders, for which there are no good animal models, and little understanding of what is happening inside cells. They will also be used to screen potential drugs, and to probe why existing drugs help some patients but not others. http://www.gopubmed.org/web/gopubmed/1?WEB01lys5moqoa0ueIuI1lI0 2,051 documents semantically analyzed 1 2 Top Years Publications 2010 821 2009 428 2008 195 2007 73 2006 59 2005 51 2004 46 2003 36 2002 30 2000 26 2001 24 1998 23 1996 20 1999 19 1991 16 1995 15 1997 14 1994 14 1993 13 1987 12 1 2 1 2 3 Top Countries Publications USA 724 Japan 265 China 130 Germany 127 United Kingdom 120 Canada 54 Spain 45 France 44 Italy 42 South Korea 35 Israel 34 Singapore 31 Australia 24 Netherlands 20 Sweden 18 Switzerland 16 Belgium 14 Taiwan 13 India 12 Iran 12 1 2 3 1 2 3 ... 20 Top Cities Publications Boston 65 Los Angeles 59 Kyoto 59 Tokyo 55 Cambridge, USA 41 New York City 35 London 32 Singapore, Singapore 31 Baltimore 30 San Francisco 28 Shanghai, China 28 Beijing, China 28 Cambridge 27 Toronto 25 Philadelphia 23 Seoul, South Korea 22 Barcelona 20 Berlin, Germany 19 Guangzhou 19 Stanford 19 1 2 3 ... 20 1 2 3 ... 31 Top Journals Publications Stem Cells 99 Cell Stem Cell 63 Nature 48 Plos One 45 Stem Cells Dev 44 J Biol Chem 41 Blood 41 Proc Natl Acad Sci U S A 35 Regen Med 30 Nat Biotechnol 27 Stem Cell Rev 26 Cell 23 J Cell Physiol 22 Exp Hematol 22 Curr Stem Cell Res Ther 22 Development 20 J Cell Biochem 20 Biochem Biophys Res Commun 20 Differentiation 20 Cell Res 18 1 2 3 ... 31 1 2 3 ... 432 Top Terms Publications Stem Cells 1,939 stem cell differentiation 1,890 stem cell development 1,889 Pluripotent Stem Cells 1,576 Animals 1,269 Humans 1,067 Embryonic Stem Cells 1,032 Mice 1,005 Cell Differentiation 973 Genes 711 Cell Line 552 Cells, Cultured 456 Transcription Factors 455 Tissues 441 Proteins 425 Fibroblasts 415 Adult 401 Gene Expression 322 generative cell differentiation 320 POU domain, class 5, transcription factor 1 320 1 2 3 ... 432 1 2 3 ... 397 Top Authors Publications Hescheler J 12 Yamanaka S 8 Benvenisty N 8 Wobus A 7 Jaenisch R 6 Hochedlinger K 6 Andrews P 6 Seidel H 6 Tai A 5 Daley G 5 Sato C 5 Mizuno H 5 Sauer H 5 Wartenberg M 5 Young H 5 Black A 5 Turhan A 5 Visani G 5 McBurney M 5 Izpisa-Belmonte J 4 1 2 3 ... 397
http://news.sciencenet.cn/htmlnews/2010/9/237025.shtm 《自然》社论：干细胞研究亟待立法解禁 http://www.gopubmed.org/web/gopubmed/1?WEB1mOWEB10O00d000j10020001000h00100090000 stem-cell research and law and Public Policy and Bioethics 56 documents semantically analyzed Top Years Publications 2004 8 2003 8 2005 7 2001 7 2002 6 2009 5 1999 4 2006 3 2000 3 2008 2 2007 2 2010 1 Top Countries Publications USA 23 Canada 4 United Kingdom 4 Germany 2 Japan 2 Belgium 1 Austria 1 Australia 1 Singapore 1 France 1 1 2 Top Cities Publications Baltimore 4 Toronto 2 Hopkins 2 Tokyo 2 Ghent 1 New York City 1 Rochester, MN, USA 1 New Haven 1 Madison 1 Kansas City 1 Wien 1 Sydney 1 Edmonton 1 Singapore, Singapore 1 St. Louis 1 Chicago 1 Princeton 1 Bochum 1 Sheffield 1 Charlottesville 1 1 2 1 2 Top Journals Publications Science 6 Kennedy Inst Ethics J 5 Perspect Biol Med 4 Bioethics 4 Reprod Biomed Online 2 Am J Bioeth 2 Natl Cathol Bioeth Q 2 Lancet 2 J Law Med 2 J Law Med Ethics 1 Yale J Health Policy Law Ethics 1 J Mol Cell Cardiol 1 Policy Stud J 1 Int J Gynaecol Obstet 1 J Bioeth Inq 1 Genewatch 1 Nat Rev Genet 1 Hec Forum 1 N J Med 1 Transplant Proc 1 1 2 1 2 3 ... 13 Top Terms Publications Humans 56 Stem Cells 51 stem cell development 49 stem cell differentiation 49 Public Policy 46 Embryo Research 39 Bioethics 32 United States 29 Embryo, Mammalian 24 Embryonic Stem Cells 23 Advisory Committees 20 Cloning, Organism 19 Morals 17 Cell Line 16 Financing, Government 15 Government Regulation 15 Morale 14 Research 14 Research Support as Topic 13 Biomedical Research 11 1 2 3 ... 13 1 2 3 4 5 Top Authors Publications Siegel A 2 Gearhart J 2 Faden R 2 Dawson L 2 Bateman-House A 2 Bok H 2 Brock D 2 Chakravarti A 2 Greene M 2 King P 2 Sachs D 2 Schill K 2 Siegel A 2 Solter D 2 Suter S 2 Verfaillie C 2 Walters L 2 Vogel G 2 Marshall E 2 Pennings G 1 1 2 3 4 5
标签: 干细胞研究
