小柯机器人

科学家综述饮食调整可增强癌症治疗
2020-03-30 15:29

美国波士顿儿童医院Naama Kanarek研究组发表综述文章,饮食调整可增强癌症治疗。该研究于2020年3月25日发表于《自然》。

肿瘤的生长和生存依赖于宿主提供的营养。改变宿主的饮食可以改变肿瘤微环境中的营养供应,这可能是抑制肿瘤生长的潜在策略。饮食调整可以限制肿瘤的营养需求,改变针对肿瘤代谢易感性的某些营养需求或增强抗癌药物的细胞毒性。

最近的报道表明,饮食中几种营养素的改变会改变癌症治疗的功效,他们对这一快速发展领域中的一些最新进展进行综述。结果表明,在癌症研究和治疗期间必须考虑患者的饮食习惯和营养状况。

附:英文原文

Title: Dietary modifications for enhanced cancer therapy

Author: Naama Kanarek, Boryana Petrova, David M. Sabatini

Issue&Volume: 2020-03-25

Abstract: Tumours depend on nutrients supplied by the host for their growth and survival. Modifications to the host’s diet can change nutrient availability in the tumour microenvironment, which might represent a promising strategy for inhibiting tumour growth. Dietary modifications can limit tumour-specific nutritional requirements, alter certain nutrients that target the metabolic vulnerabilities of the tumour, or enhance the cytotoxicity of anti-cancer drugs. Recent reports have suggested that modification of several nutrients in the diet can alter the efficacy of cancer therapies, and some of the newest developments in this quickly expanding field are reviewed here. The results discussed indicate that the dietary habits and nutritional state of a patient must be taken into account during cancer research and therapy.

DOI: 10.1038/s41586-020-2124-0

Source: https://www.nature.com/articles/s41586-020-2124-0

Nature:《自然》,创刊于1869年。隶属于施普林格·自然出版集团,最新IF:43.07
官方网址:http://www.nature.com/
投稿链接:http://www.nature.com/authors/submit_manuscript.html


本期文章:《自然》:Online/在线发表

分享到:

0