美国冷泉港实验室Adam Kepecs小组发现,眶额皮层神经元编码信心的表现形式。该项研究成果于2020年6月5日在线发表在《细胞》杂志上。
Title: Behavior- and Modality-General Representation of Confidence in Orbitofrontal Cortex
Author: Paul Masset, Torben Ott, Armin Lak, Junya Hirokawa, Adam Kepecs
Issue&Volume: 2020-06-05
Abstract: Every decision we make is accompanied by a sense of confidence about its likely outcome.This sense informs subsequent behavior, such as investing more—whether time, effort,or money—when reward is more certain. A neural representation of confidence shouldoriginate from a statistical computation and predict confidence-guided behavior. Anadditional requirement for confidence representations to support metacognition isabstraction: they should emerge irrespective of the source of information and informmultiple confidence-guided behaviors. It is unknown whether neural confidence signalsmeet these criteria. Here, we show that single orbitofrontal cortex neurons in ratsencode statistical decision confidence irrespective of the sensory modality, olfactoryor auditory, used to make a choice. The activity of these neurons also predicts twoconfidence-guided behaviors: trial-by-trial time investment and cross-trial choicestrategy updating. Orbitofrontal cortex thus represents decision confidence consistentwith a metacognitive process that is useful for mediating confidence-guided economicdecisions.
DOI: 10.1016/j.cell.2020.05.022
Source: https://www.cell.com/cell/fulltext/S0092-8674(20)30617-6
本期文章:《细胞》:Online/在线发表