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基因组学前沿改善人类健康的战略构想
2020-10-31 20:35

美国国立卫生研究院Eric D. Green等研究人员讨论了基因组学前沿改善人类健康的战略构想。这一论文发表在2020年10月28日出版的国际学术期刊《自然》上。

据研究人员介绍,从三十年前启动人类基因组计划开始,一直到2003年完成之后,基因组学已逐渐在基础和转化研究中发挥核心作用。此外,越来越多的研究表明,基因组信息可如何有效地用于临床护理。在未来,技术发展、生物学见解和临床应用(以及其他方面)的预期进展将导致基因组学在生物医学研究几乎所有领域中得到更广泛的整合,并将基因组学纳入主流医学和公共卫生实践,此外,基因组学在日常生活中的重要性也与日俱增。
 
美国国家人类基因组研究院最近代表研究界完成了一项多年的战略参与过程,从而确定了人类基因组学的未来研究重点和机遇,其重点在于健康应用。研究人员描述了为人类基因组学的前沿研究而设想的最优先的要素,即“基因组学的前沿”。
 
附:英文原文

Title: Strategic vision for improving human health at The Forefront of Genomics

Author: Eric D. Green, Chris Gunter, Leslie G. Biesecker, Valentina Di Francesco, Carla L. Easter, Elise A. Feingold, Adam L. Felsenfeld, David J. Kaufman, Elaine A. Ostrander, William J. Pavan, Adam M. Phillippy, Anastasia L. Wise, Jyoti Gupta Dayal, Britny J. Kish, Allison Mandich, Christopher R. Wellington, Kris A. Wetterstrand, Sarah A. Bates, Darryl Leja, Susan Vasquez, William A. Gahl, Bettie J. Graham, Daniel L. Kastner, Paul Liu, Laura Lyman Rodriguez, Benjamin D. Solomon, Vence L. Bonham, Lawrence C. Brody, Carolyn M. Hutter, Teri A. Manolio

Issue&Volume: 2020-10-28

Abstract: Starting with the launch of the Human Genome Project three decades ago, and continuing after its completion in 2003, genomics has progressively come to have a central and catalytic role in basic and translational research. In addition, studies increasingly demonstrate how genomic information can be effectively used in clinical care. In the future, the anticipated advances in technology development, biological insights, and clinical applications (among others) will lead to more widespread integration of genomics into almost all areas of biomedical research, the adoption of genomics into mainstream medical and public-health practices, and an increasing relevance of genomics for everyday life. On behalf of the research community, the National Human Genome Research Institute recently completed a multi-year process of strategic engagement to identify future research priorities and opportunities in human genomics, with an emphasis on health applications. Here we describe the highest-priority elements envisioned for the cutting-edge of human genomics going forward—that is, at ‘The Forefront of Genomics’.

DOI: 10.1038/s41586-020-2817-4

Source: https://www.nature.com/articles/s41586-020-2817-4

Nature:《自然》,创刊于1869年。隶属于施普林格·自然出版集团,最新IF:43.07
官方网址:http://www.nature.com/
投稿链接:http://www.nature.com/authors/submit_manuscript.html


本期文章:《自然》:Online/在线发表

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