美国国立卫生研究院Eric D. Green等研究人员讨论了基因组学前沿改善人类健康的战略构想。这一论文发表在2020年10月28日出版的国际学术期刊《自然》上。
Title: Strategic vision for improving human health at The Forefront of Genomics
Author: Eric D. Green, Chris Gunter, Leslie G. Biesecker, Valentina Di Francesco, Carla L. Easter, Elise A. Feingold, Adam L. Felsenfeld, David J. Kaufman, Elaine A. Ostrander, William J. Pavan, Adam M. Phillippy, Anastasia L. Wise, Jyoti Gupta Dayal, Britny J. Kish, Allison Mandich, Christopher R. Wellington, Kris A. Wetterstrand, Sarah A. Bates, Darryl Leja, Susan Vasquez, William A. Gahl, Bettie J. Graham, Daniel L. Kastner, Paul Liu, Laura Lyman Rodriguez, Benjamin D. Solomon, Vence L. Bonham, Lawrence C. Brody, Carolyn M. Hutter, Teri A. Manolio
Abstract: Starting with the launch of the Human Genome Project three decades ago, and continuing after its completion in 2003, genomics has progressively come to have a central and catalytic role in basic and translational research. In addition, studies increasingly demonstrate how genomic information can be effectively used in clinical care. In the future, the anticipated advances in technology development, biological insights, and clinical applications (among others) will lead to more widespread integration of genomics into almost all areas of biomedical research, the adoption of genomics into mainstream medical and public-health practices, and an increasing relevance of genomics for everyday life. On behalf of the research community, the National Human Genome Research Institute recently completed a multi-year process of strategic engagement to identify future research priorities and opportunities in human genomics, with an emphasis on health applications. Here we describe the highest-priority elements envisioned for the cutting-edge of human genomics going forward—that is, at ‘The Forefront of Genomics’.