小柯机器人

美国哈佛大学Aravinthan D.T. Samuel、Vladislav Susoy和Vivek Venkatachalam团队合作发现，在秀丽隐杆线虫交配过程中，对自然环境的感知诱发不同的大脑活动。相关论文于2021年9月16日发表在《细胞》杂志上。

在本研究中，研究人员使用全脑神经元成像系统探究了雄性线虫交配时的整体行为。研究表明，随着交配在一系列组件行为中展开，大脑在每个组件之间具有相似的运行行为，但在不同组件之间存在明显的运行差异。当考虑完整的感官和行为背景时，每个神经元都发挥着独特作用。神经元之间的功能相关性不是固定的，而是随着行为动力学而变化。

从单个神经元到整体神经回路，该研究展示了线虫在对自然环境的感官知觉和运动动作整合过程中如何产生不同的大脑动态。

研究人员表示，自然目标导向行为通常与许多刺激触发成分的复杂序列有关。了解大脑回路如何组织这些行为需要绘制动物、环境和神经系统之间的相互作用图。

附：英文原文

Title: Natural sensory context drives diverse brain-wide activity during C. elegans mating

Author: Vladislav Susoy, Wesley Hung, Daniel Witvliet, Joshua E. Whitener, Min Wu, Core Francisco Park, Brett J. Graham, Mei Zhen, Vivek Venkatachalam, Aravinthan D.T. Samuel

Issue&Volume: 2021-09-16

Abstract: Natural goal-directed behaviors often involve complex sequences of many stimulus-triggeredcomponents. Understanding how brain circuits organize such behaviors requires mappingthe interactions between an animal, its environment, and its nervous system. Here,we use brain-wide neuronal imaging to study the full performance of mating by theC. elegans male. We show that as mating unfolds in a sequence of component behaviors, the brainoperates similarly between instances of each component but distinctly between differentcomponents. When the full sensory and behavioral context is taken into account, uniqueroles emerge for each neuron. Functional correlations between neurons are not fixedbut change with behavioral dynamics. From individual neurons to circuits, our studyshows how diverse brain-wide dynamics emerge from the integration of sensory perceptionand motor actions in their natural context.

DOI: 10.1016/j.cell.2021.08.024

Source: https://www.cell.com/cell/fulltext/S0092-8674(21)00998-3