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研究绘制出婴儿阶段人脑的多面图谱
2023-01-04 14:39

美国北卡罗来纳大学Pew-Thian Yap团队绘制出婴儿阶段人脑的多面图谱。这一研究成果于2022年12月30日在线发表在国际学术期刊《自然—方法学》上。

研究人员介绍了一组联合表面-体积图谱,以时空密集的方式描绘了人类大脑从两周到两岁的产后发育。这个特定月份图谱描绘了规范的模式,并捕捉了早期大脑发育的关键特征,因此有利于识别正常发育轨迹中的异常情况。这些图谱将提高人们对早期结构和功能发展的理解,因为它有助于将婴儿大脑的不同特征映射到一个共同的参考框架中,以便对皮层和皮层下的变化进行精确的多层面量化。
 
据悉,脑图谱是整合、处理和分析从不同个体、来源和规模收集的大脑特征的空间参考。
 
附:英文原文

Title: Multifaceted atlases of the human brain in its infancy

Author: Ahmad, Sahar, Wu, Ye, Wu, Zhengwang, Thung, Kim-Han, Liu, Siyuan, Lin, Weili, Li, Gang, Wang, Li, Yap, Pew-Thian

Issue&Volume: 2022-12-30

Abstract: Brain atlases are spatial references for integrating, processing, and analyzing brain features gathered from different individuals, sources, and scales. Here we introduce a collection of joint surface–volume atlases that chart postnatal development of the human brain in a spatiotemporally dense manner from two weeks to two years of age. Our month-specific atlases chart normative patterns and capture key traits of early brain development and are therefore conducive to identifying aberrations from normal developmental trajectories. These atlases will enhance our understanding of early structural and functional development by facilitating the mapping of diverse features of the infant brain to a common reference frame for precise multifaceted quantification of cortical and subcortical changes.

DOI: 10.1038/s41592-022-01703-z

Source: https://www.nature.com/articles/s41592-022-01703-z

Nature Methods:《自然—方法学》,创刊于2004年。隶属于施普林格·自然出版集团,最新IF:47.99
官方网址:https://www.nature.com/nmeth/
投稿链接:https://mts-nmeth.nature.com/cgi-bin/main.plex


本期文章:《自然—方法学》:Online/在线发表

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