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精神病学家Julien Mendlewicz的学术成就
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科研生涯与学术成就：
http://f1000medicine.com/member/1981940042108305
http://www.ulb.ac.be/rech/inventaire/chercheurs/2/CH762.html
Julien Mendlewicz
School of Medicine, University of Brussels, Belgium
主要论著与被引用情况：
http://scholar.google.com/scholar?q=Julien+Mendlewicz&hl=en&btnG=Search&as_sdt=2001&as_sdtp=on
P LINKOWSKI, J MENDLEWICZ, R … - Journal of Clinical …, 1985 - Endocrine Soc
Both unipolar and bipolar depressed patients had higher 24-h mean cortisol levels (P <
0.01) than normal men, but no significant difference in 24-h mean ACTH level was found. The
nadir of cortisol secretion occurred almost 3 h earlier in older normal subjects and ...
Cited by 345 - Related articles - All 6 versions
Both unipolar and bipolar depressed patients had higher 24-h mean cortisol levels (P <
0.01) than normal men, but no significant difference in 24-h mean ACTH level was found. The
nadir of cortisol secretion occurred almost 3 h earlier in older normal subjects and ...
Cited by 345 - Related articles - All 6 versions
[CITATION] Adoption study supporting genetic transmission in manic-depressive illness.
Cited by 321 - Related articles - All 4 versions
… , A Luxen, V De Maertelaer, P Hubain, J Mendlewicz … - Biological …, 1994 - Elsevier
The authors investigated brain glucose utilization using positron emission tomography (PET)
in 12 normal volunteers and 12 unipolar unmedicated depressed patients (six endogenous;
six nonendogenous) following injection of [18F]fluoro-deoxyglucose (FDG). Compared by ...
Cited by 164 - Related articles - All 5 versions
The authors investigated brain glucose utilization using positron emission tomography (PET)
in 12 normal volunteers and 12 unipolar unmedicated depressed patients (six endogenous;
six nonendogenous) following injection of [18F]fluoro-deoxyglucose (FDG). Compared by ...
Cited by 164 - Related articles - All 5 versions
J Mendlewicz, S Sevy, H Brocas, P Simon, F Charon, S … - The Lancet, 1987 - Elsevier
Heredity is an important factor in vulnerability to manic depression. A genetic linkage has been
demonstrated between manic depression and coagulation factor IX at Xq27 with a TaqI polymorphism
at the F9 locus in DNA samples from peripheral leucocytes of manic depressive probands ...
Cited by 145 - Related articles - All 5 versions
Heredity is an important factor in vulnerability to manic depression. A genetic linkage has been
demonstrated between manic depression and coagulation factor IX at Xq27 with a TaqI polymorphism
at the F9 locus in DNA samples from peripheral leucocytes of manic depressive probands ...
Cited by 145 - Related articles - All 5 versions
… , E Lindström, J Mendlewicz, G Racagni, LS … - European …, 1998 - Elsevier
The prevention of relapse in schizophrenia remains an enormous public health challenge worldwide
and improvements in this area can have tremendous impact on morbidity, mortality and quality
of life, as well as direct and indirect health care costs. Though there has been debate as ...
Cited by 141 - Related articles - All 5 versions
The prevention of relapse in schizophrenia remains an enormous public health challenge worldwide
and improvements in this area can have tremendous impact on morbidity, mortality and quality
of life, as well as direct and indirect health care costs. Though there has been debate as ...
Cited by 141 - Related articles - All 5 versions
J Mendlewicz, JL Fleiss, RR Fieve - Jama, 1972 - Am Med Assoc
Seven families were found in which manic-depressive illness and either protan or deutan color
blindness (X-linked recessive traits) occurred in successive generations. In these seven
families, as well as in two others previously reported in the literature, detailed analysis ...
Cited by 127 - Related articles - All 3 versions
Seven families were found in which manic-depressive illness and either protan or deutan color
blindness (X-linked recessive traits) occurred in successive generations. In these seven
families, as well as in two others previously reported in the literature, detailed analysis ...
Cited by 127 - Related articles - All 3 versions
… , E SHELLEY, J MENDLEWICZ, RR … - American Journal of …, 1973 - Am Psychiatric Assoc
The authors studied 52 manic-depressive patients who were assigned to either lithium or placebo
during their normal interval phases for periods up to 28 months. Patients receiving lithium had
fewer manic and depres- sive episodes per patient-year than placebo patients. However, ...
Cited by 120 - Related articles - All 2 versions
The authors studied 52 manic-depressive patients who were assigned to either lithium or placebo
during their normal interval phases for periods up to 28 months. Patients receiving lithium had
fewer manic and depres- sive episodes per patient-year than placebo patients. However, ...
Cited by 120 - Related articles - All 2 versions
J MENDLEWICZ, P LINKOWSKI, M … - Journal of Clinical …, 1985 - Endocrine Soc
Both unipolar and bipolar depressed patients secreted more GH than normal men (mean ±
SD, 441 ± 189 µg/24 h for unipolar depressed men; 357 ± 143 µg/24 h for bipolar depressed
men vs. 172 ± 101 µg/24 h for normal men (P < 0.01). This hypersecretion occurred ...
Cited by 101 - Related articles - All 3 versions
Both unipolar and bipolar depressed patients secreted more GH than normal men (mean ±
SD, 441 ± 189 µg/24 h for unipolar depressed men; 357 ± 143 µg/24 h for bipolar depressed
men vs. 172 ± 101 µg/24 h for normal men (P < 0.01). This hypersecretion occurred ...
Cited by 101 - Related articles - All 3 versions
J MENDLEWICZ, RR FIEVE, F … - American Journal of …, 1973 - Am Psychiatric Assoc
MOUNTING EVIDEKCE for the long-term stabilizing prop- erties of lithium in bipolar manic-depressive
illness is found in several controlled longitudinal studies (1-5): Al- though the time periods during
which the patients were studied are not always comparable in these reports and criticisms ...
Cited by 110 - Related articles - All 2 versions
MOUNTING EVIDEKCE for the long-term stabilizing prop- erties of lithium in bipolar manic-depressive
illness is found in several controlled longitudinal studies (1-5): Al- though the time periods during
which the patients were studied are not always comparable in these reports and criticisms ...
Cited by 110 - Related articles - All 2 versions
… , M Monclus, D Wikler, P Damhaut, J Mendlewicz, S … - Neuroscience …, 1996 - Elsevier
Serotonergic mechanisms are involved in gender-related behaviors and psychiatric conditions
like aggression, eating disorders, depression, impulsivity or suicide. We studied gender differences
in the living human brain type-2 serotonin receptor (5HT 2 r). Twenty-two healthy age- ...
Cited by 104 - Related articles - All 4 versions
Serotonergic mechanisms are involved in gender-related behaviors and psychiatric conditions
like aggression, eating disorders, depression, impulsivity or suicide. We studied gender differences
in the living human brain type-2 serotonin receptor (5HT 2 r). Twenty-two healthy age- ...
Cited by 104 - Related articles - All 4 versions
Partial response and nonresponse to antidepressant therapy: current approaches and treatment options
Background: Response to antidepressant drug therapy is less than optimal for a considerable
proportion of depressed patients; at present, however, few data exist to guide their rational therapeutic
management. This review describes general principles for the management of such ...
Cited by 106 - Related articles - BL Direct - All 3 versions
… , C Vizuete, I Morlán, J Bobes, J Mendlewicz - Journal of Psychiatric …, 1997 - Elsevier
We searched for regional cerebral metabolic disturbances in patients with borderline personality
disorder (BPD). Ten inpatients with BPD, no current DSM-IIIR Axis I diagnosis and free of any
psychotropic substances, were compared with 15 age-matched control subjects using ...
Cited by 99 - Related articles - All 4 versions
We searched for regional cerebral metabolic disturbances in patients with borderline personality
disorder (BPD). Ten inpatients with BPD, no current DSM-IIIR Axis I diagnosis and free of any
psychotropic substances, were compared with 15 age-matched control subjects using ...
Cited by 99 - Related articles - All 4 versions
nih.gov [PDF]J Mendlewicz, JD Rainer - American Journal of Human Genetics, 1974 - ncbi.nlm.nih.gov
INTRODUCTION Twin and family studies of manic-depressive (bipolar) illness strongly suggest
the presence of a genetic factor in the etiology of this disease. Concordance rates for the illness
in monozygotic twins are consistently greater than the rates found in dizygotic twins [1]. ...
Cited by 93 - Related articles - All 3 versions
INTRODUCTION Twin and family studies of manic-depressive (bipolar) illness strongly suggest
the presence of a genetic factor in the etiology of this disease. Concordance rates for the illness
in monozygotic twins are consistently greater than the rates found in dizygotic twins [1]. ...
Cited by 93 - Related articles - All 3 versions
… González-Torrecillas, J Mendlewicz … - International …, 2005 - Cambridge Univ Press
ABSTRACT. This study was made in an attempt todocument the effects of early treatment of poststroke
depression (including fluoxetine treatment) on neuro- psychological rehabilitation (including
cognitive function). Assessment mea- sures used included the Schedule for Affective ...
Cited by 89 - Related articles - BL Direct - All 2 versions
ABSTRACT. This study was made in an attempt todocument the effects of early treatment of poststroke
depression (including fluoxetine treatment) on neuro- psychological rehabilitation (including
cognitive function). Assessment mea- sures used included the Schedule for Affective ...
Cited by 89 - Related articles - BL Direct - All 2 versions
… , RC Kessler, J Mendlewicz, G Racagni, AY … - …, 2000 - content.karger.com
Epidemiological studies clearly indicate that posttraumatic stress disorder (PTSD) is becoming
a major health concern worldwide even if still poorly recognized and not well treated. PTSD commonly
co-occurs with other psychiatric disorders, and several symptoms overlap with major ...
Cited by 93 - Related articles - BL Direct - All 6 versions
Epidemiological studies clearly indicate that posttraumatic stress disorder (PTSD) is becoming
a major health concern worldwide even if still poorly recognized and not well treated. PTSD commonly
co-occurs with other psychiatric disorders, and several symptoms overlap with major ...
Cited by 93 - Related articles - BL Direct - All 6 versions
… , M Kerkhofs, D Bosson, J Mendlewicz, … - American Journal of …, 1993 - Am Physiological Soc
Twin study of the 24-h cortisol profile: ... PAUL LINKOWSKI, ANNE VAN ONDERBERGEN, MYRIAM
KERKHOFS, ... DANIELLE BOSSON, JULIEN MENDLEWICZ, AND EVE VAN CAUTER ... Sleep
Laboratory, Department of Psychiatry, Erasme Hospital, Institute of Interdisciplinary ...
Cited by 91 - Related articles - BL Direct - All 3 versions
Twin study of the 24-h cortisol profile: ... PAUL LINKOWSKI, ANNE VAN ONDERBERGEN, MYRIAM
KERKHOFS, ... DANIELLE BOSSON, JULIEN MENDLEWICZ, AND EVE VAN CAUTER ... Sleep
Laboratory, Department of Psychiatry, Erasme Hospital, Institute of Interdisciplinary ...
Cited by 91 - Related articles - BL Direct - All 3 versions
J Mendlewicz, P Linkowski, J Wilmotte - The British Journal of Psychiatry, 1980 - RCP
Heredity is known to be an important contributing factor in the vulnerability to manic-depressive
psychosis. Family, twin and adoptionstudiescorroboratethe geneticdia thesis for the illness, but
these studies do not elucidate the mode of transmission of manic depressive psychosis, ( ...
Cited by 83 - Related articles - All 6 versions
Heredity is known to be an important contributing factor in the vulnerability to manic-depressive
psychosis. Family, twin and adoptionstudiescorroboratethe geneticdia thesis for the illness, but
these studies do not elucidate the mode of transmission of manic depressive psychosis, ( ...
Cited by 83 - Related articles - All 6 versions
J Mendlewicz, M Baron - The British Journal of Psychiatry, 1981 - RCP
It has been the recent practice to discriminate between bipolar and unipolar affective
disorders. Bipolar patients have a cyclical manic-depressive course of illness while unipolar
patients only manifest depressions. Bipolar patients have more affective illnesses ...
Cited by 72 - Related articles - All 3 versions
It has been the recent practice to discriminate between bipolar and unipolar affective
disorders. Bipolar patients have a cyclical manic-depressive course of illness while unipolar
patients only manifest depressions. Bipolar patients have more affective illnesses ...
Cited by 72 - Related articles - All 3 versions
J Mendlewicz, JL Fleiss, M Cataldo, JD … - Archives of General …, 1975 - Am Med Assoc
We interviewed available spouses and first-degree relatives of 140 bipolar and unipolar probands
for current and past psychopathology, and assessed interrater reliability. Diagnoses based on
direct interviews of relatives were compared with those based on reports of the probands ...
Cited by 63 - Related articles - All 3 versions
We interviewed available spouses and first-degree relatives of 140 bipolar and unipolar probands
for current and past psychopathology, and assessed interrater reliability. Diagnoses based on
direct interviews of relatives were compared with those based on reports of the probands ...
Cited by 63 - Related articles - All 3 versions
J Mendlewicz, G Charles, JM Franckson - The British Journal of Psychiatry, 1982 - RCP
Summary: Plasma cortisol suppression after dexamethasone administration in 113 consecutively
hospitalized patients (54 patients with primary depression, 41 with secondary depression and
18 non-depressed controls) showed early morning hypersecretion of cortisol and cortisol ...
Cited by 61 - Related articles - All 3 versions
Summary: Plasma cortisol suppression after dexamethasone administration in 113 consecutively
hospitalized patients (54 patients with primary depression, 41 with secondary depression and
18 non-depressed controls) showed early morning hypersecretion of cortisol and cortisol ...
Cited by 61 - Related articles - All 3 versions
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