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愚人节Nature这一期关注人类的基因组,还配了一个Opinion,十年人的基因组(OPINION HUMAN GENOME at TEN)。有两篇文章很有意思,配套的图片很有趣:
Point: Hypotheses first
There is little to show for all the time and money invested in genomic studies of cancer, says Robert Weinberg — and the approach is undermining tried-and-tested ways of doing, and of building, science.
Counterpoint: Data first
Large, unbiased genomic surveys are taking cancer therapeutics in directions that could never have been predicted by traditional molecular biology, says Todd Golub.
十年前人的基因组被测序的时候,大家认为基因组时代的到来,今天大家同样认为是基因组时代的到来,但是真正解决的问题在哪,研究的出发点在哪,貌似还是迷糊,下一个十年又是什么样的情况呢?今天的布局能不能赢下一个十年?科学同样也有赌博的味道,为了下一个十年能赶在前面,现在就要出发。
今天虽然是愚人节,我想NATURE应该不会把人类基因组作为愚人的节目,把全世界又娱乐下。不过十年前人类基因组测序到有点愚人的味道,就现在看来。十年后呢?
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