博文
科学家 Bruce S McEwen（生理学）
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科研生涯与实验室：
http://www.rockefeller.edu/labheads/mcewen/mcewen-lab.php
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研究成果与论著：
http://www.rockefeller.edu/labheads/mcewen/publications.php
部分论著与科研绩效：
http://scholar.google.com/scholar?hl=en&q=Bruce+S+McEwen&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0
BS McEwen - The New England Journal of Medicine, 1998 - endo.gr
This article reviews the long-term effect of the physiologic response to stress, which I refer to
as allostatic load. 2 Allostasis — the ability to achieve stability through change 3 — is critical
to survival. Through allostasis, the autonomic nervous system, the hypothalamic–pituitary– ...
Cited by 2171 - Related articles - Cached - BL Direct - All 10 versions
RM Sapolsky, LC Krey, BS McEwen - Science's SAGE KE, 2002 - sageke.sciencemag.org
Abstract: Over the past 5 yr, we have examined some of the sharpest edges of the pathology
of aging. We have studied the capacity of aged organisms to respond appropriately to stress
and the capacity of stress to cumulatively damage aging tissue. The idea of a relationship ...
Cited by 1131 - Related articles - All 6 versions
Abstract: Over the past 5 yr, we have examined some of the sharpest edges of the pathology
of aging. We have studied the capacity of aged organisms to respond appropriately to stress
and the capacity of stress to cumulatively damage aging tissue. The idea of a relationship ...
Cited by 1131 - Related articles - All 6 versions
angelfire.com [PDF]BS McEwen - Annual review of neuroscience, 1999 - Annual Reviews
? Abstract The hippocampus is a target of stress hormones, and it is an especially plastic and
vulnerable region of the brain. It also responds to gonadal, thyroid, and adrenal hormones, which
modulate changes in synapse formation and dendritic structure and regulate dentate ...
Cited by 890 - Related articles - BL Direct - All 9 versions
? Abstract The hippocampus is a target of stress hormones, and it is an especially plastic and
vulnerable region of the brain. It also responds to gonadal, thyroid, and adrenal hormones, which
modulate changes in synapse formation and dendritic structure and regulate dentate ...
Cited by 890 - Related articles - BL Direct - All 9 versions
endojournals.org [HTML]BS McEwen, SE Alves - Endocrine reviews, 1999 - Endocrine Soc
GONADAL hormones affect the nervous system in ways that extend beyond their essential actions
of regulating gonadotropin and PRL secretion and modulating sexual behavior. For
example, estrogens and androgens have been reported to influence verbal fluency, ...
Cited by 849 - Related articles - BL Direct - All 8 versions
GONADAL hormones affect the nervous system in ways that extend beyond their essential actions
of regulating gonadotropin and PRL secretion and modulating sexual behavior. For
example, estrogens and androgens have been reported to influence verbal fluency, ...
Cited by 849 - Related articles - BL Direct - All 8 versions
pnas.org [HTML]… P Tanapat, BS McEwen, G Flügge, E … - Proceedings of the …, 1998 - National Acad Sciences
Although granule cells continue to be added to the dentate gyrus of adult rats and tree
shrews, this phenomenon has not been demonstrated in the dentate gyrus of adult primates.
To determine whether neurons are produced in the dentate gyrus of adult primates, adult ...
Cited by 748 - Related articles - BL Direct - All 15 versions
Although granule cells continue to be added to the dentate gyrus of adult rats and tree
shrews, this phenomenon has not been demonstrated in the dentate gyrus of adult primates.
To determine whether neurons are produced in the dentate gyrus of adult primates, adult ...
Cited by 748 - Related articles - BL Direct - All 15 versions
jneurosci.org [PDF]… , CS Woolley, M Frankfurt, BS McEwen - Journal of …, 1990 - Soc Neuroscience
... Elizabeth Gould, Catherine S. Woolley, Maya Frankfurt, and Bruce S. McEwen Laboratory
of Neuroendocrinology, The Rockefeller University, New York, New York 10021 Gonadal
steroids are known to influence hippocampal phys- iology in adulthood. ...
Cited by 710 - Related articles - All 5 versions
... Elizabeth Gould, Catherine S. Woolley, Maya Frankfurt, and Bruce S. McEwen Laboratory
of Neuroendocrinology, The Rockefeller University, New York, New York 10021 Gonadal
steroids are known to influence hippocampal phys- iology in adulthood. ...
Cited by 710 - Related articles - All 5 versions
BS McEwen, E Stellar - Archives of Internal Medicine, 1993 - Am Med Assoc
Objective This article presents a new formulation of the relationship between stress and the processes
leading to disease. It emphasizes the hidden cost of chronic stress to the body over long time
periods, which act as a predisposing factor for the effects of acute, stressful life events. It ...
Cited by 785 - Related articles - BL Direct - All 3 versions
Objective This article presents a new formulation of the relationship between stress and the processes
leading to disease. It emphasizes the hidden cost of chronic stress to the body over long time
periods, which act as a predisposing factor for the effects of acute, stressful life events. It ...
Cited by 785 - Related articles - BL Direct - All 3 versions
BS McEwen, RM Sapolsky - Current Opinion in Neurobiology, 1995 - Elsevier
Stress affects cognition in a number of ways, acting rapidly via catecholamines and more slowly
via glucocorticoids. Catecholamine actions involve beta adrenergic receptors and also availability
of glucose, whereas glucocorticoids biphasically modulate synaptic plasticity over hours ...
Cited by 755 - Related articles - All 5 versions
Stress affects cognition in a number of ways, acting rapidly via catecholamines and more slowly
via glucocorticoids. Catecholamine actions involve beta adrenergic receptors and also availability
of glucose, whereas glucocorticoids biphasically modulate synaptic plasticity over hours ...
Cited by 755 - Related articles - All 5 versions
cjb.net [HTML]E Gould, BS McEwen, P Tanapat, LAM Galea, … - Journal of …, 1997 - neuro.cjb.net
These studies were designed to determine whether adult neurogenesis occurs in the dentate
gyrus of the tree shrew, an animal phylogenetically between insectivores and primates, and to
explore the possibility that this process is regulated by stressful experiences and NMDA ...
Cited by 722 - Related articles - BL Direct - All 11 versions
These studies were designed to determine whether adult neurogenesis occurs in the dentate
gyrus of the tree shrew, an animal phylogenetically between insectivores and primates, and to
explore the possibility that this process is regulated by stressful experiences and NMDA ...
Cited by 722 - Related articles - BL Direct - All 11 versions
jneurosci.org [PDF]RM Sapolsky, LC Krey, BS McEwen - Journal of Neuroscience, 1985 - Soc Neuroscience
The hippocampus of the rat loses neurons with age, a loss which may eventuate in some of the
functional impairments typical of senescence. Cumulative exposure to cotticoster- one
(CORT) over the lifespan may be a cause of this neuronal loss, as it is prevented by ...
Cited by 667 - Related articles - All 5 versions
The hippocampus of the rat loses neurons with age, a loss which may eventuate in some of the
functional impairments typical of senescence. Cumulative exposure to cotticoster- one
(CORT) over the lifespan may be a cause of this neuronal loss, as it is prevented by ...
Cited by 667 - Related articles - All 5 versions
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