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咖啡与颈椎病基因与生物学研究的知识发现

已有 4890 次阅读 2010-12-10 16:23 |个人分类:知识发现|系统分类:论文交流|关键词:学者| 基因, 生物学, 知识发现, 咖啡, 颈椎病

博主:受周公朴的博文启发,刚才做了知识发现的分析,供大家研究参考。

[病例分析1]喝咖啡与颈椎病

周公朴的博客 http://www.sciencenet.cn/m/user_content.aspx?id=392236#t1

我的怀疑是:喝咖啡可能会引起颈椎疾病

        我以前不喝咖啡,大约5-6年前,第一次喝咖啡时,觉得颈项后面两侧有分别有两股“流”上冲,至头顶后侧的两边,人不是变精神了,而是发困,有一种被麻醉的感觉。以后再喝咖啡的时候,脖子后面有“流”(——也许是神经电流?)上冲的情况,慢慢就弱化了,现在基本没有了。这个不细说了。

       关键是,喝了几次,感觉到脖子转动颈椎骨头就开始嘎嘎作响。一直到现在,不喝咖啡就好些,喝了咖啡转脖子的响声就大些,骨头之间的阻力也大些。怀疑喝咖啡会引起钙的流失。呵呵。也许是疑心病。

本周开始决定不喝咖啡了,等一段时间,再看结果。

如果有人有同样的感受,或者你正在做这项研究。希望我的陈述对你有帮助。

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi

 

Start A-Literature C-Literature B-list Filter Literature
A-query: cervical spondylosis
C-query: Coffee
The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 0 articles appeared in both literatures. The results of this search are saved under id # 4234 and can be accessed from the start page after you leave this session. There are 242 terms on the current B-list (27 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin.

To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

Rank   Prob   B-term

Restrict by semantic categories?

 

咖啡与颈椎病 相关基因与生物学研究的知识发现(知识点),对科研选题和研究有重要参考价值。

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/view_b_txt.cgi?ID=4234

job id # 4234 started Fri Dec 10 04:00:52 2010
Max_citations: 50000
Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
4234 Search ARROWSMITH A
A_query_raw: cervical spondylosis Fri Dec 10 04:01:16 2010

A query = cervical spondylosis started Fri Dec 10 04:01:16 2010
A query resulted in 5754 titles
4234 Search ARROWSMITH C
C_query_raw: Coffee Fri Dec 10 04:01:55 2010

C: Coffee 7920

A: pubmed_query_A 5754

AC: ( cervical spondylosis ) AND ( Coffee ) 0

C query = Coffee started Fri Dec 10 04:01:55 2010
C query resulted in 7920 titles
A AND C query resulted in 0 titles
3247 B-terms ready on Fri Dec 10 04:02:54 2010

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
242 B-terms left after filter executed Fri Dec 10 04:04:31 2010

B-list on Fri Dec 10 04:06:06 2010
1 bone mineral density
2 moyamoya disease
3 twin
4 vitamin d receptor
5 diabetes
6 mri
7 ct
8 parkinson disease
9 bone mineral content
10 carpal tunnel syndrome
11 hip
12 e genotype
13 meta
14 diabetes mellitus
15 axis
16 neurofibromatosis
17 bph
18 apolipoprotein e
19 pain
20 cleft
21 estrogen receptor
22 nail
23 osteo
24 gtp binding protein
25 cord
26 kk
27 proteoglycan

咖啡与骨矿物质密度的关系;颈椎病与骨矿物质密度的关系的研究课题。

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/show_sentences.cgi

 

Start A-Literature C-Literature B-list Filter Literature

AB literature

B-term

BC literature

cervical spondylosis  颈椎病 bone mineral density 骨矿物质密度 Coffee  咖啡
1: High bone mineral density in pycnodysostotic patients with a novel mutation in the propeptide of cathepsin K. 2007
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2: Intra-individual variation in lumbar bone mineral density as a measure of spondylotic deformity in the elderly. 2003
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3: Inverse relation between osteoporosis and spondylosis in postmenopausal women as evaluated by bone mineral density and semiquantitative scoring of spinal degeneration. 2003
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4: [Separate measurement of radial trabecular and cortical bone mineral density by peripheral quantitative computed tomography (pQCT) in degenerative joint disease] 1999
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5: Degenerative lumbar listhesis and bone mineral density in elderly women. The study of osteoporotic fractures. 1999
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6: Correlation between bone mineral density and intervertebral disc degeneration. 1998
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1: Coffee consumption and CYP1A2 genotype in relation to bone mineral density of the proximal femur in elderly men and women: a cohort study. 2010
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2: Bone mineral density and perceived menopausal symptoms: factors influencing low back pain in postmenopausal women. 2009
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3: Coffee consumption and bone mineral density in dialysis patients. 2008
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4: Diet and lifestyle associated with increased bone mineral density: cross-sectional study of Japanese elderly women at an osteoporosis outpatient clinic. 2007
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5: Habitual tea drinking and bone mineral density in postmenopausal Turkish women: investigation of prevalence of postmenopausal osteoporosis in Turkey (IPPOT Study). 2007
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6: Effects of coffee consumption and smoking habit on bone mineral density. 2006
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7: Evaluation of methods for prediction of bone mineral density by clinical and biochemical variables in perimenopausal women. 2001
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8: Tea drinking and bone mineral density in older women. 2000
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9: Is caffeine associated with bone mineral density in young adult women? 2000
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10: [The effect of smoking tobacco and drinking of alcohol and coffee on bone mineral density of healthy men 40 years of age] 2000
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11: Bone mineral density and aortic calcification: the Study of Osteoporotic Fractures. 1997
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12: [A population survey on bone mineral density in a fishing village in Wakayama prefecture. (Part 1) Distribution of bone mineral density by sex and age based on a representative sample of the community] 1996
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