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多发性硬化症与视神经脊髓炎研究的知识发现

已有 3091 次阅读 2010-12-28 09:08 |个人分类:知识发现|系统分类:论文交流|关键词:学者| 知识发现, 多发性硬化症, 视神经脊髓炎

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi?refresh=T&ID=29705

Start A-Literature C-Literature B-list Filter Literature
  A-query: multiple sclerosis
C-query: neuromyelitis optica
The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 821 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 29705 and can be accessed from the start page after you leave this session. There are 580 terms on the current B-list (76 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin.

To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

job id # 29705 started Mon Dec 27 20:41:30 2010
Max_citations: 50000
Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
29705 Search ARROWSMITH A
A_query_raw: multiple sclerosisMon Dec 27 20:46:41 2010

A query = multiple sclerosis started Mon Dec 27 20:46:41 2010
A query resulted in 47517 titles
29705 Search ARROWSMITH C
C_query_raw: neuromyelitis optica Mon Dec 27 20:46:54 2010

C: neuromyelitis optica 925

A: pubmed_query_A 47517

AC: ( multiple sclerosis ) AND ( neuromyelitis optica ) 821

C query = neuromyelitis optica started Mon Dec 27 20:46:54 2010
C query resulted in 925 titles
A AND C query resulted in 821 titles
580 B-terms ready on Mon Dec 27 20:50:12 2010

B-list on Mon Dec 27 20:51:17 2010
1 fmri study
2 functional mri
3 antiphospholipid
4 aquaporin-4
5 brain mri
6 rituximab
7 mitoxantrone
8 transverse myelitis
9 experimental autoimmune encephalomyelitis
10 expression blood brain
11 spinal cord tumor
12 disseminated encephalomyelitis
13 aquaporin
14 myelitis
15 acute disseminated encephalomyelitis
16 demyelinating optic
17 autoimmune encephalomyelitis
18 chronic progressive myelopathy
19 htlv i
20 acute transverse
21 lymphotropic virus i
22 corpus callosum atrophy
23 optic neuritis
24 antiphospholipid antibody
25 neuromyelitis
26 anti aquaporin
27 demyelinating optic neuritis
28 tacrolimus
29 htlv
30 optic neuropathy
31 fmri
32 t lymphotropic virus
33 acute transverse myelitis
34 il-10
35 human t lymphotropic
36 demyelinating optic neuropathy
37 htlv i associated
38 cortical demyelination
39 autologous peripheral
40 cord tumor
41 stem cell transplantation
42 opticospinal
43 experimental autoimmune
44 brain magnetic resonance
45 aquaporin antibody
46 efficacy safety mitoxantrone
47 spinal cord barrier
48 recurrent optic neuritis
49 autoimmune encephalomyelitis rat
50 case demyelinating
51 optic neuritis a
52 internuclear ophthalmoplegia
53 hematopoietic stem cell
54 brain mri lesion
55 hematopoietic stem
56 immunodominant
57 compressive myelopathy
58 demyelination
59 varicella zoster
60 bilateral internuclear ophthalmoplegia
61 efns
62 t cell determinant
63 myelopathy
64 upregulation
65 devic syndrome
66 anti aquaporin antibody
67 tnf alpha il-10
68 demyelinating lesion
69 acute disseminated
70 mri lesion
71 dystrophin
72 neuritis
73 tnf alpha
74 myasthenia gravis
75 primary sjogren syndrome
76 autoimmunity

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/show_sentences.cgi

Start A-Literature C-Literature B-list Filter Literature

AB literature

 

B-term

 

BC literature

 

multiple sclerosis brain mri neuromyelitis optica
1: Brain MRI findings in long-standing and disabling multiple sclerosis in 84 patients. 2010
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2: [A case of immune-mediated encephalopathy showing refractory epilepsy and extensive brain MRI lesions associated with anti-glutamic acid decarboxylase antibody] 2010
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3: [Association analysis between candidate genes for multiple sclerosis and brain MRI parameters] 2010
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4: Recurrent epileptic seizures with multifocal brain MRI lesions after paternal lymphocyte immunization: A causal relationship to multiple sclerosis? 2010
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5: Multi-scale Amplitude Modulation-Frequency Modulation (AM-FM) Texture Analysis of Multiple Sclerosis in Brain MRI Images. 2010
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6: HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study. 2010
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7: [Approaches to segment multiple-sclerosis lesions on conventional brain MRI] 2009
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8: Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis. 2009
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9: Detection and measurement of coverage loss in interleaved multi-acquisition brain MRIs due to motion-induced inter-slice misalignment. 2009
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10: Pediatric optic neuritis: brain MRI abnormalities and risk of multiple sclerosis. 2009
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11: Efficacy of treatment of MS with IFNbeta-1b or glatiramer acetate by monthly brain MRI in the BECOME study. 2009
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12: Sorting through the pediatric MS spectrum with brain MRI. 2009
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13: Signal abnormalities on 1.5 and 3 Tesla brain MRI in multiple sclerosis patients and healthy controls. A morphological and spatial quantitative comparison study. 2009
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14: Brain MRI Lesion Load at 1.5T and 3T versus Clinical Status in Multiple Sclerosis. 2009
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15: A fuzzy region-based hidden markov model for partial-volume classification in brain MRI. 2009
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16: Retinal nerve fiber layer thickness is associated with brain MRI outcomes in multiple sclerosis. 2008
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17: Diagnostic value of contrast-enhanced fluid-attenuated inversion-recovery and delayed contrast-enhanced brain MRI in multiple sclerosis. 2008
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18: Acute transverse myelitis with normal brain MRI : long-term risk of MS. 2008
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19: Optic neuritis and the risk of multiple sclerosis--what can we learn from a brain MRI scan? 2008
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20: Once-weekly 22microg subcutaneous IFN-beta-1a in secondary progressive MS: a 3-year follow-up study on brain MRI measurements and serum MMP-9 levels. 2007
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21: Relation of vision to global and regional brain MRI in multiple sclerosis. 2007
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22: Unified approach for multiple sclerosis lesion segmentation on brain MRI. 2006
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23: Brain MRI in late-onset multiple sclerosis. 2005
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24: Optimizing brain MRI protocols in the follow-up of patients with multiple sclerosis T2-weighted MRI of the brain after the administration of gadopentetate dimeglumine. 2005
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25: Cardiovascular autonomic dysfunction correlates with brain MRI lesion load in MS. 2004
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26: [The contribution of automatic anatomical matching of sequential brain MRI scans in the monitoring of multiple sclerosis lesions] 2004
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27: Spontaneously T1-hyperintense lesions of the brain on MRI: a pictorial review. 2003
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28: The relation between brain MRI lesions and depressive symptoms in multiple sclerosis. 2003
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29: Serum cytokine levels do not correlate with disease activity and severity assessed by brain MRI in multiple sclerosis. 2002
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30: [Quantitative analysis techniques for brain MRI: applications in multiple sclerosis] 2002
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31: Quantitative diffusion characteristics of the human brain depend on MRI sequence parameters. 2002
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32: Brain MRI lesion load quantification in multiple sclerosis: a comparison between automated multispectral and semi-automated thresholding computer-assisted techniques. 2002
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33: [What can be expected from brain MRI in early-stage multiple sclerosis?] 2001
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34: Intra-observer, inter-observer and inter-scanner variations in brain MRI volume measurements in multiple sclerosis. 2001
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35: Correlations of brain MRI parameters to disability in multiple sclerosis. 2001
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36: Fatigue in MS: cross-sectional correlation with brain MRI. 2000
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37: Diagnostic brain MRI findings in primary progressive multiple sclerosis. 2000
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38: Interaction between HLA-DR2 and abnormal brain MRI in optic neuritis and early MS. Optic Neuritis Study Group. 2000
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39: Brain MRI lesions and atrophy are related to depression in multiple sclerosis. 2000
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40: Psychological stress and the subsequent appearance of new brain MRI lesions in MS. 2000
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41: Reproducibility of brain MRI lesion volume measurements in multiple sclerosis using a local thresholding technique: effects of formal operator training. 1999
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42: Short-term evolution of new multiple sclerosis lesions enhancing on standard and triple dose gadolinium-enhanced brain MRI scans. 1999
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43: High numbers of perforin mRNA expressing CSF cells in multiple sclerosis patients with gadolinium-enhancing brain MRI lesions. 1999
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44: Correlation between enhancing lesion number and volume on standard and triple dose gadolinium-enhanced brain MRI scans from patients with multiple sclerosis. 1999
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45: Brain MRI correlates of magnetization transfer imaging metrics in patients with multiple sclerosis. 1999
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46: Fatigue in multiple sclerosis: cross-sectional correlation with brain MRI findings in 71 patients. 1999
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47: Lesion load quantification on fast-FLAIR, rapid acquisition relaxation-enhanced, and gradient spin echo brain MRI scans from multiple sclerosis patients. 1999
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48: Multiple sclerosis: interobserver agreement in reporting active lesions on serial brain MRI using conventional spin echo, fast spin echo, fast fluid-attenuated inversion recovery and post-contrast T1-weighted images. 1999
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49: Effect of training and different measurement strategies on the reproducibility of brain MRI lesion load measurements in multiple sclerosis. 1998
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50: Intrathecal synthesis of virus-specific oligoclonal IgG, and of free kappa and free lambda oligoclonal bands in acute monosymptomatic optic neuritis. Comparison with brain MRI. 1998
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51: The prognostic value of brain MRI in clinically isolated syndromes of the CNS. A 10-year follow-up. 1998
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52: The effect of repositioning on brain MRI lesion load assessment in multiple sclerosis: reliability of subjective quality criteria. 1998
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53: A comparison between the sensitivities of 3-mm and 5-mm thick serial brain MRI for detecting lesion volume changes in patients with multiple sclerosis. 1998
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54: A longitudinal brain MRI study comparing the sensitivities of the conventional and a newer approach for detecting active lesions in multiple sclerosis. 1998
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55: How does brain MRI lesion volume change on serial scans in patients with multiple sclerosis? 1998
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56: Brain MRI lesion volume measurement reproducibility is not dependent on the disease burden in patients with multiple sclerosis. 1998
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57: A pyramidal approach for automatic segmentation of multiple sclerosis lesions in brain MRI. 1998
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58: Balo's concentric sclerosis: a clinical case study of brain MRI, biopsy, and proton magnetic resonance spectroscopic findings. 1997
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59: Interscanner variation in brain MRI lesion load measurements in MS: implications for clinical trials. 1997
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60: The influence of slice orientation on brain MRI lesion load measurement in multiple sclerosis. 1997
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61: Spinal MRI in patients with suspected multiple sclerosis and negative brain MRI. 1996
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62: Patterns of disease activity in multiple sclerosis patients: a study with quantitative gadolinium-enhanced brain MRI and cytokine measurement in different clinical subgroups. 1996
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63: Correlation between brain MRI lesion volume and disability in patients with multiple sclerosis. 1996
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64: Isolated optic neuritis and its prognosis for multiple sclerosis: a clinical and paraclinical study with evoked potentials. CSF examination and brain MRI. 1996
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65: Validity of brain MRI as the primary outcome criterion in multiple sclerosis phase II clinical trials. 1996
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66: [Brain MRI in multiple sclerosis] 1996
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67: A brain MRI study of different types of chronic-progressive multiple sclerosis. 1995
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68: Correlations between changes in disability and T2-weighted brain MRI activity in multiple sclerosis: a follow-up study. 1995
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69: Brain MRI correlates of cognitive impairment in primary and secondary progressive multiple sclerosis. 1995
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70: Intra- and inter-observer agreement of brain MRI lesion volume measurements in multiple sclerosis. A comparison of techniques. 1995
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71: Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis. 1994
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72: Relationship between bladder dysfunction and brain MRI in multiple sclerosis. 1991
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1: Brain MRI lesions characteristic of neuromyelitis optica and positive anti-aquaporin 4-antibody may predict longitudinal extensive myelitis and optic neuritis in Sjogren's syndrome. 2010
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