路透社消息：除非能很好的控制糖尿病,否则结核病将在世界范围内加速蔓延。糖尿病能削弱人体免疫力,从而增加这种肺病的患病风险。

WHO数据显示在全球结核病每年导致150万人丧生，这种细菌以休眠状态蛰伏在很多人体内。因肥胖导致糖尿病流行，糖尿病损害人体免疫力，从而使蛰伏的TB发病，呈现疾病共患状态。这并不是全球首次面对共患感染。HIV/AIDS流行摧毁了上百万人的系统免疫力，曾导致非洲有些国家TB发生率增长了四倍。如今，大夫们担心糖尿病导致这种状况再次在包括很多贫穷国家中发生。最大的担心是到2035年，10个大国中有6个将拥有最大数量的糖尿病患者，它们是中国，印度，巴西，印尼，巴基斯坦和俄罗斯，这些国家为WHO认定的TB高负担国家。

来自抗结核和肺病国际联盟（International Union Against Tuberculosis and Lung Disease）的Anthony Harries告诉路透社记者，他最担心的是印度和中国，印度TB发生率全球最高，中国紧随其后，而中国是全球糖尿病第一大国，印度则紧随其后。我们要警惕莫让历史在TB与糖尿病上重演。

多数属于2型糖尿病病例，该型糖尿病与西化饮食方式和静止的生活方式所致的肥胖有关。如不现在就动手应对，以防患于未然，我们将遭遇TB与糖尿病共患的大流行，将影响上百万人，并导致宝贵的公共健康系统资源枯竭，来自世界糖尿病基金会（World Diabetes Foundation）的Anil Kapur认为。

糖尿病并不象HIV所致AIDS-TB共患严重，这种病毒导致AIDS，增高患TB风险30倍，但世界上患糖尿病者则十倍于HIV病人，因此它们的影响类似。在巴塞罗那举办的国际性肺病研讨会上，Harries和Kapur研究组的联合报告释出的（这一）案例呼唤国际联合行动，以应对迫在眉睫的TB-糖尿病流行。这份报告打破了以往只关系单一感染性疾病的传统方式。应对这一挑战需要对TB病人检查糖尿病，对糖尿病患者检查TB，并提供对这两种疾病的处理方案，报告中说，而当前并未对两种疾病开展双向的协调检查。

原文：Experts sound alarm as diabetes fuels cases of TB

(Reuters) - Cases of tuberculosis are set accelerate worldwide unless action is taken to curb diabetes, a chronic condition that weakens the immune system and triples the risk a person will develop the lung disease, health experts warned on Wednesday.

Tuberculosis (TB), which killed an estimated 1.5 million people last year according to the World Health Organization (WHO), is caused by bacteria that lie dormant in many people.

However, diabetics TB become sick from latent TB infection far more often than other people because their immune systems are compromised -- a fact that could unleash an epidemic of co-infection as diabetes rates soar along with growing obesity.

It is not the first time that the world has been confronted with such co-infection. The HIV/AIDS pandemic, which destroyed the immune systems of millions, lead to a quadrupling of TB rates in many countries in Africa.

Now doctors fear a re-run of that scenario as diabetes takes hold around the world, including in many poorer countries.

The big worry is that six of the top 10 countries projected to have the greatest numbers of diabetics by 2035 -- China, India, Brazil, Indonesia, Pakistan, and Russia -- are classified as high TB burden countries by the WHO.

Anthony Harries of the International Union Against Tuberculosis and Lung Disease told Reuters he was most concerned about India and China, since India has the world's highest TB rate, followed by China, while for diabetes China has the most cases, followed by India.

"We want to raise an alarm that we don’t watch history repeat itself with TB-diabetes,” he said.

Diabetes affected 382 million people in 2013 and will increase to a projected 592 million by 2035, according to the International Diabetes Federation.

Most of the cases will be of Type 2 diabetes, the kind that is linked to obesity and is driven by the adoption of Western diets and more sedentary lifestyles.

"If we don’t act now to head this off, we’re going to experience a co-epidemic of TB-diabetes that will impact millions and sap public health systems of precious resources. The key is to prevent this from happening,” Anil Kapur of the World Diabetes Foundation said.

While diabetes is not as great a co-infection threat as HIV, the virus that causes AIDS raises the risk of TB by thirty fold, there are about 10 times as many cases of diabetes in the world as people living with HIV, so the overall impact is similar.

A joint report from Harries' and Kapur's groups presented at an international lung conference in Barcelona sets out the case for international action against the looming co-epidemic.

The report challenges the conventional approach of tackling independently infectious diseases, like TB, and chronic non-communicable diseases, like TB.

Fighting the threat will need a clear strategy of screening both diabetes patients for TB and TB patients for diabetes, as well as providing treatments for both diseases, the report says. Such "bi-directional" screening is at present patchy.

上文由群晓科苑翻译整理，科学推广，服务民众。他人或机构如需使用，请提供该原始链接地址。

北京群晓科苑生物技术有限公司主要经营生物医药领域的试剂、耗材和仪器。群晓生物致力于为用户提供优质的材料、技术和实验整体性解决方案，完美配合用户的科研创意和灵感。群晓生物立志把一流的产品、专业的技术和完善的售后服务献给广大用户。

北京群晓科苑生物技术有限公司

www.qbioscience.com

www.qbiotec.com

Tel: 010-84504282/64880108

qbioscience@126.com