可控制癌症基因开关的分子首次合成

http://news.sciencenet.cn/htmlnews/2010/9/238029.shtm

http://www.nature.com/nature/journal/vnfv/ncurrent/abs/nature09504.html

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi

 

Start A-Literature C-Literature B-list Filter Literature

A-query: bromodomain C-query: Epigenetic proteins The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 25 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 9291 and can be accessed from the start page after you leave this session. There are 264 terms on the current B-list (151 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

 

 

job id # 9291 started Mon Sep 27 02:24:36 2010
Max_citations: 50000
Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
9291 Search ARROWSMITH A
A_query_raw: bromodomain and extra-terminal Mon Sep 27 02:26:23 2010

A query = bromodomain and extra-terminal started Mon Sep 27 02:26:24 2010
A query resulted in 4 titles
9291 Search ARROWSMITH A
A_query_raw: bromodomain Mon Sep 27 02:27:26 2010

A query = bromodomain started Mon Sep 27 02:27:26 2010
A query resulted in 361 titles
9291 Search ARROWSMITH C
C_query_raw: Epigenetic proteins Mon Sep 27 02:27:35 2010

C: Epigenetic proteins 9242

A: pubmed_query_A 361

AC: ( bromodomain ) AND ( Epigenetic proteins ) 25

C query = Epigenetic proteins started Mon Sep 27 02:27:35 2010
C query resulted in 9242 titles
A AND C query resulted in 25 titles
1547 B-terms ready on Mon Sep 27 02:28:26 2010

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
264 B-terms left after filter executed Mon Sep 27 02:29:44 2010

B-list on Mon Sep 27 02:33:10 2010
1 e2f
2 wnt
3 mecp2
4 zinc finger protein
5 brca1
6 stat3
7 cancer testis antigen
8 swi snf
9 gcn5
10 interferon regulatory factor
11 sp1
12 ash1
13 kap1
14 creb binding protein
15 swi2
16 pcaf
17 mll
18 iswi
19 aurora b
20 retinoic acid receptor
21 chromatin remodeling
22 cbp
23 histone acetyltransferase
24 swi
25 h2ax
26 p300
27 creb
28 gene promoter
29 homeotic gene
30 eralpha
31 transporter gene
32 homeotic
33 c myc
34 myod
35 pml
36 brg1
37 hdac1
38 testis specific
39 histone acetylation gene
40 tif1alpha
41 p tefb
42 tefb
43 rdna
44 chaperone
45 e2f-1
46 rna polymerase i
47 containing gene
48 mek
49 acetylation gene
50 histone deacetylase
51 repressor
52 cbp p300
53 exon
54 snf
55 prb
56 phd finger
57 myb
58 genome reprogramming
59 transcription factor
60 histone h4
61 e2f1
62 genome wide
63 norc
64 e1a
65 tata binding protein
66 chromatin remodeling protein
67 erk
68 h2a
69 rbp2
70 novel gene
71 cyclin
72 wstf
73 snf2
74 tumor suppressor gene
75 rna polymerase
76 gene silencing
77 kap-1
78 c jun
79 ret
80 candidate tumor suppressor
81 tata
82 receptor tyrosine kinase
83 estrogen receptor
84 asf1
85 tyrosine kinase
86 myc
87 expression gene
88 ets
89 sumo
90 p53
91 dna binding
92 glycogen synthase
93 vdr
94 androgen receptor
95 intron
96 ribosomal gene
97 testis specific gene
98 tif1beta
99 oncogene
100 h2a z
101 h4
102 gene encoding
103 atf-2
104 high mobility group
105 cdna
106 brahma
107 brm
108 oncogene expression
109 glucocorticoid receptor
110 histone gene
111 tbp
112 gene chromosome 3p21
113 cell cycle progression
114 tat
115 tumor suppressor
116 nuclear localization signal
117 c fos
118 gene repression
119 bet
120 hmr
121 isoform
122 response element
123 orc
124 gene chromosome
125 gene acute myeloid
126 chromatin template
127 promoter
128 acetyltransferase
129 viral oncogene
130 ku
131 g1
132 c myb
133 gene associated
134 suppressor gene
135 rb
136 box
137 open reading frame
138 male genome reprogramming
139 reading frame
140 gene euchromatin
141 jun
142 gtpase
143 ras
144 phd
145 barr
146 genomic
147 gene involved
148 prostate cancer
149 human gene
150 nuclear protein
151 histone
152 acf

 

 

 

 

 

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